Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Liriodendron chinense
Species name
Liriodendron chinense is a species of flowering plant in the family Magnoliaceae (magnolia family).
Species info
Gene sequence info
Liriodendron_chinense.4CL.fa
Download
>Lchi04097
MEKSGYGKDGIYRSLRPPLIIPTDQNLSMVPFLFRNSSSYPQTLAIADADTGESLTFAAFKSTVNNVARGLFRLGIAKGDVVLIFAPNSLYFPLCFLGTVALGAIATTVNPLYTPTELSKQAVDSRPKLIVTVPQLWDKVKDLRLPAVIIGSRNHTPPIISNHKITYFEDLISGSLPDLPPVLIRQSDTAALLYSSGTTGISKGVILTHHNFISAALMVCADQENEGEGHNTFLCFLPLFHIFGLSVITYAQLQRGNSLVTMGRFDLEAVLRAVEKYRVTYLFVVPPVMIALAKQSITRKYDLSSLKKLGSGAAPLGKDIMEECAKNFPQALVVQEMPVKGFRRQSASEDVTRREKRQMEKSGYGKDGIYRSLRPPLIFPTDQNLSMVPFLFRNSSSYPQALAIADADTGESLTFAAFKSTVNNVARGLFRLGIAKGDVVLIFAPNSLYFPLCFFGTVALGAIATTVNPLYTHTELSKQAVDSRPKLIVTVPQLWDKVKDLRLPAVIIGSRNHTPPIISNHKITYFEDLISGPLPDLPPVLIRQSDTAALLYSSGTTGISKGVILTHRNFISAALMVCAYQENEGEGRNTFLCFLPLFHIFGLSVITYAQLQRGNSLVTMGRFDLEAVLRAVEKYRVTYLFVVPPVMIALAKQSITRKYDLSSLKLLGSGAAPLGKDIMEECAKNFPQAFIGQGYGLTESCGIVSLENPKGGVRHYGSAGTLVPGVESKIVSVDTLKPLPPNQLGEIWLQGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFDDEGRLYVVDRIKELIKYKGFQVAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSPKSSLTEEHVKEFIAKQVAPFKKLRRVTFVNSVPKSAAGKILRRELIEKVRSKL
>Lchi23417
LEVALRSFQEQGSDEFLLRGRTWLAEPECGLCCGREAVSEHVEPEVAQWVVFRTGLTGFRLELGYGMGLTRVSLAEFGLGIWGQSNTVALLFSSGTTSTSKGMVLTHHNFISASLMASTDQENDSEDRKS
>Lchi03598
MDAINDYIYRSKLPNIDIPAHLPLHSYCFQNMAEFQSKPCLINGATGDIYTYEEVDLIARKVAAGLDKIGIEQGHVIMLLLPNSPEFVFAFLGASHRGAMATTANPFYTANEIAKQARACSPRLIITQACYVEKVRDLAHGNDVKIMCIDSPPEGCLHFSELMEADENNIPAVDISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIVALMELVEKYKISIAPFVPPIVLAIAKSPVVDDYDLSSIRTVMSGAAPMGKELEDAVRVKLPNATLGQGYGMTEAGPVLSMCLAFAKDPFQIKSGSCGTVVRNAELKIVDPETGASLPRNQAGEICIRGAQIMKGYLNDPESTKKTIDKDGWLHTGDVGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLINNRDIADAAVVPMKDYLTGEIPVAFVVRSNGSKITEEEIKQYIAKQVVFYKKIHRVFFVDAIPKAPSGKILRKDLRAKLAAGFPN
>Lchi01200
MLSVASPDTQPPTPTPEGPPSETFIFRSRLPDISLSNHLPLHTYCFERALEFPDRPCLITGSNGRIYSYAETHLICQKTAAGLSKLGIKKGDVIMVLLQNSPEFVFSFMGASIIGAVTTAGNPFCTPAEIYKQFSSSAAKLVITHSQYVTKLRDAGEKFSTIGDELPVITIDDPPENCLHFSVISSADEREVPSVSIEPDDPVALPFSSGTTGFPKGVILTHKSLISSVAQQIDGENPNLQLTPEDVVLCVLPLFHIFSLNSVLLCSLRAVSGVLLMQKFEIGTLLDLIQRYRVSVAMVVPPLVLALAKNPTVENFDLSSIRIILSGAAPLGKELEDALRSRVPQATLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGFSLQHNQPGEICIRGPQIMKGYLNDPKATASTIDAEGWLHTGDIGYVDDDEEIYIVDRVKELIKFKGFQASSKDTFIYQVPPAELEALLVSHPSIADAAVVPQKDVAAGEVPVAFVVPSNGYDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPAGKILRKDLRAKLATSS
>Lchi03237
MEKQPQNSDFIYRSKLPDIEIPNDVLLHTYCFEKVAHFADRPCLIDGATGHIYTYADVDLTVRKVAAGLDKLGIEKGHVIMLLLPNTPEFVFAFFGASRRGATTTMANPFYTPNEVSKQAKACDARLIITQACYVDKVRDLAKESDIKIMTIDSPLDGCLHFSELLTADENQIPAVEISPDDVVALPYSSGTTGLPKGAMLTHKGQVTSVAQQVDGDNPNLYMHSEDVVLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFEIVALMELVQRYKVSIAAIVPPIMLAIAKSPVVDKYDLSSIRTIMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFAIKSGACGTVVRNAELKIVDPETGASLPRNQPGEICIRGAQIMKGYLNDPESTKITIDKDGWLHTGDIGLVDNDDELFIVDRLKEIIKYKGFQVAPAELEAMLIAHPKIADAAVVPMKDEAAGEIPVAFVIKSNGSDITEDEIKQYISKQVVFYKRIGRVFFVEAIPKAPSGKILRKDLRAKLAAGSPN
>Lchi35131
MATTANPFYTANEIAKQARACSPRLIITQACYVEKVRDLAHGNDVKIMCIDSPPEGCLHFSELMEADENNIPAVDISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIVALMELVEKYKISIAPFVPPIVLAIAKSPVVDDYDLSSIRTVMSGAAPMGKELEDAVRVKLPNATLGQGYGMTEAGPVLSMCLAFAKDPFQIKSGSCGTVVRNAELKIVDPETGASLPRNQAGEICIRGAQIMKDGWLHTGDVGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLINNRDIADAL
>Lchi10806
MSQPTFPPLLKPFPFSSHLPNTHMMEKQSHETSVQKQEEEYIFQSQFPAVPVPDNLTLPEFVLQEAELFADKVAIVEVVTGKEYTYKQVNRDTQRFAKALRSLGLRKGCVVVVALPNVAEYAIVALGIMSAGGVFSGANPQAHATEIQKQVEDSDAKLIVTNGSSYDKVKGLNLPIILVGDDRVAGAIYWDDLLAAAERAGTDTVDDAVNQNDLCALPYSSGTTGTSKGVMLTHRNLVANLCSSLFSVGPDMVGQVTILGLMPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLSALITHEVNFAPIVPPIMLALVKNPIVEEFDLHRLKLKTVMTAAAPLAP
>Lchi00400
MPVGQSDTAALLYSSGMTGINKGVVLTHHNFISASLMASVDQENDSLVSGLWSYEQLWSLVMRATLVSGYASSPGLWSLVMQAVLVSGLYSLIFGLWYMGSVEVDHDEECMEETSAYQLLSTASPDISGIYGDPQVPPRVGNEYQVEIPPLTTESGRLQPIRHPTDTKQMFDVDNSIQIGLPIPVMWVHDVVDQMKHEQLEFFGNMIVADTTRAIDSEVVGDEMDMDLSLQQLKMPSLDNKCESKGYIPVPGSLGGSWSDIEQESFILGLYIFGKNLIQVQRFVGSKDMGDVQSFYYGKFYRSEGHRRWSECRKMRSRRCIHGQRIFTGWRQHELLSRLLPHMSEESGNTLHETLGEGKVSLEEYVSTLKAMVGLNILVEAVGVGKGKHDLTGVAMEPVKANPPISTRSELPVGKACSSLSSAEIIKFLTGDFRLSKARSNDLFWEAVWPRLLASGWHSEQPKNNGYATSKASLVFLIPGIKKFSRRKLVKGNHYFDSVSDVLNKVAADPMLLEFEVEAVHGDRMKEENGPKNPSKERDDNDSSEDEPADEPASADKISNDQEDSFPTTFDDKKGMLIDGLDYAINLSKQGTVVGGLHDNCEDRYPDLLNKQHPRKSIKRQFSRRVESVRPKYLSPILKRRRLNACNREESRRCTNALPTGPHLNEEERQWQSHSLEASNTVVTEVVGPSQPKVSASSSGKGSADGSSGCILSENGFSISTVSETVSHDKPQKRALIDLNLPHLLPDFETDGPFIEAADSQEDFSTKGSSFPPESNQGHEDSWAPVTSNGMDSADLPVANSRRQSTRNRPLTTRVLEALECGFFNTRRRGRGTKAQPRGNLMPRPPRRRRGARDGVRVSDSGNAGTDITGFPGRWGG
>Lchi27732
MDWIIHEWAPPSYYNNNNNNNYKKKKKEREREGLPLDSQRPGDAAAQQGQPDPRIGTWHLRARSREWGTTEAVGTKVNDREFMPVGQSDTAALLYSSGMTGINKGVVLTHHNFISASLMASADQENDYLLISRWKELRQNERALGLATRFQHANSFSAVTSLILQYQHPIPVEQYDSARPSRATSSSVVSVLSASPSFSEAMTPTTGVSFLFGSYDSNYGFQFIMTHQRYYYAYRQPV
>Lchi05053
MDAINDYIYRSKLPNIDIPAHLPLHSYCFQNMAQFQSKPCLINGATGDIYTYEEVDLIARKVAAGLDKIGIEQGHVIMLLLPNSPEFVFAFLGASHRGAMATTANPFYTANEIAKQARACSPRLIITQACYVEKVRDLAHGNDVKIMCIDSPPEGCLHFSELMEADENNIPAVDISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIVALMELAEKYKISIAPFVPPIVLAIAKSPVVDDYDLSSIRTVMSGAAPMGKELEDAVRAKLPNATLGQGYGMTEAGPVLSMCLAFAKDPFQIKSGSCGTVVRNAELKIVDPETGASLPRNQAGEICIRGAQIMKGYLNDPESTKKTIDKDGWLHTGDVGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLINNHDIADAAVVPMKDYLTGEIPVAFVVRSNGSKITEEEIKQYIAKQVVFYKKIHRVFFVDAIPKAPSGKILRKDLRAKLAAGFPN
MEKSGYGKDGIYRSLRPPLIIPTDQNLSMVPFLFRNSSSYPQTLAIADADTGESLTFAAFKSTVNNVARGLFRLGIAKGDVVLIFAPNSLYFPLCFLGTVALGAIATTVNPLYTPTELSKQAVDSRPKLIVTVPQLWDKVKDLRLPAVIIGSRNHTPPIISNHKITYFEDLISGSLPDLPPVLIRQSDTAALLYSSGTTGISKGVILTHHNFISAALMVCADQENEGEGHNTFLCFLPLFHIFGLSVITYAQLQRGNSLVTMGRFDLEAVLRAVEKYRVTYLFVVPPVMIALAKQSITRKYDLSSLKKLGSGAAPLGKDIMEECAKNFPQALVVQEMPVKGFRRQSASEDVTRREKRQMEKSGYGKDGIYRSLRPPLIFPTDQNLSMVPFLFRNSSSYPQALAIADADTGESLTFAAFKSTVNNVARGLFRLGIAKGDVVLIFAPNSLYFPLCFFGTVALGAIATTVNPLYTHTELSKQAVDSRPKLIVTVPQLWDKVKDLRLPAVIIGSRNHTPPIISNHKITYFEDLISGPLPDLPPVLIRQSDTAALLYSSGTTGISKGVILTHRNFISAALMVCAYQENEGEGRNTFLCFLPLFHIFGLSVITYAQLQRGNSLVTMGRFDLEAVLRAVEKYRVTYLFVVPPVMIALAKQSITRKYDLSSLKLLGSGAAPLGKDIMEECAKNFPQAFIGQGYGLTESCGIVSLENPKGGVRHYGSAGTLVPGVESKIVSVDTLKPLPPNQLGEIWLQGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFDDEGRLYVVDRIKELIKYKGFQVAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSPKSSLTEEHVKEFIAKQVAPFKKLRRVTFVNSVPKSAAGKILRRELIEKVRSKL
>Lchi23417
LEVALRSFQEQGSDEFLLRGRTWLAEPECGLCCGREAVSEHVEPEVAQWVVFRTGLTGFRLELGYGMGLTRVSLAEFGLGIWGQSNTVALLFSSGTTSTSKGMVLTHHNFISASLMASTDQENDSEDRKS
>Lchi03598
MDAINDYIYRSKLPNIDIPAHLPLHSYCFQNMAEFQSKPCLINGATGDIYTYEEVDLIARKVAAGLDKIGIEQGHVIMLLLPNSPEFVFAFLGASHRGAMATTANPFYTANEIAKQARACSPRLIITQACYVEKVRDLAHGNDVKIMCIDSPPEGCLHFSELMEADENNIPAVDISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIVALMELVEKYKISIAPFVPPIVLAIAKSPVVDDYDLSSIRTVMSGAAPMGKELEDAVRVKLPNATLGQGYGMTEAGPVLSMCLAFAKDPFQIKSGSCGTVVRNAELKIVDPETGASLPRNQAGEICIRGAQIMKGYLNDPESTKKTIDKDGWLHTGDVGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLINNRDIADAAVVPMKDYLTGEIPVAFVVRSNGSKITEEEIKQYIAKQVVFYKKIHRVFFVDAIPKAPSGKILRKDLRAKLAAGFPN
>Lchi01200
MLSVASPDTQPPTPTPEGPPSETFIFRSRLPDISLSNHLPLHTYCFERALEFPDRPCLITGSNGRIYSYAETHLICQKTAAGLSKLGIKKGDVIMVLLQNSPEFVFSFMGASIIGAVTTAGNPFCTPAEIYKQFSSSAAKLVITHSQYVTKLRDAGEKFSTIGDELPVITIDDPPENCLHFSVISSADEREVPSVSIEPDDPVALPFSSGTTGFPKGVILTHKSLISSVAQQIDGENPNLQLTPEDVVLCVLPLFHIFSLNSVLLCSLRAVSGVLLMQKFEIGTLLDLIQRYRVSVAMVVPPLVLALAKNPTVENFDLSSIRIILSGAAPLGKELEDALRSRVPQATLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGFSLQHNQPGEICIRGPQIMKGYLNDPKATASTIDAEGWLHTGDIGYVDDDEEIYIVDRVKELIKFKGFQASSKDTFIYQVPPAELEALLVSHPSIADAAVVPQKDVAAGEVPVAFVVPSNGYDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPAGKILRKDLRAKLATSS
>Lchi03237
MEKQPQNSDFIYRSKLPDIEIPNDVLLHTYCFEKVAHFADRPCLIDGATGHIYTYADVDLTVRKVAAGLDKLGIEKGHVIMLLLPNTPEFVFAFFGASRRGATTTMANPFYTPNEVSKQAKACDARLIITQACYVDKVRDLAKESDIKIMTIDSPLDGCLHFSELLTADENQIPAVEISPDDVVALPYSSGTTGLPKGAMLTHKGQVTSVAQQVDGDNPNLYMHSEDVVLCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFEIVALMELVQRYKVSIAAIVPPIMLAIAKSPVVDKYDLSSIRTIMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFAIKSGACGTVVRNAELKIVDPETGASLPRNQPGEICIRGAQIMKGYLNDPESTKITIDKDGWLHTGDIGLVDNDDELFIVDRLKEIIKYKGFQVAPAELEAMLIAHPKIADAAVVPMKDEAAGEIPVAFVIKSNGSDITEDEIKQYISKQVVFYKRIGRVFFVEAIPKAPSGKILRKDLRAKLAAGSPN
>Lchi35131
MATTANPFYTANEIAKQARACSPRLIITQACYVEKVRDLAHGNDVKIMCIDSPPEGCLHFSELMEADENNIPAVDISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIVALMELVEKYKISIAPFVPPIVLAIAKSPVVDDYDLSSIRTVMSGAAPMGKELEDAVRVKLPNATLGQGYGMTEAGPVLSMCLAFAKDPFQIKSGSCGTVVRNAELKIVDPETGASLPRNQAGEICIRGAQIMKDGWLHTGDVGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLINNRDIADAL
>Lchi10806
MSQPTFPPLLKPFPFSSHLPNTHMMEKQSHETSVQKQEEEYIFQSQFPAVPVPDNLTLPEFVLQEAELFADKVAIVEVVTGKEYTYKQVNRDTQRFAKALRSLGLRKGCVVVVALPNVAEYAIVALGIMSAGGVFSGANPQAHATEIQKQVEDSDAKLIVTNGSSYDKVKGLNLPIILVGDDRVAGAIYWDDLLAAAERAGTDTVDDAVNQNDLCALPYSSGTTGTSKGVMLTHRNLVANLCSSLFSVGPDMVGQVTILGLMPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLSALITHEVNFAPIVPPIMLALVKNPIVEEFDLHRLKLKTVMTAAAPLAP
>Lchi00400
MPVGQSDTAALLYSSGMTGINKGVVLTHHNFISASLMASVDQENDSLVSGLWSYEQLWSLVMRATLVSGYASSPGLWSLVMQAVLVSGLYSLIFGLWYMGSVEVDHDEECMEETSAYQLLSTASPDISGIYGDPQVPPRVGNEYQVEIPPLTTESGRLQPIRHPTDTKQMFDVDNSIQIGLPIPVMWVHDVVDQMKHEQLEFFGNMIVADTTRAIDSEVVGDEMDMDLSLQQLKMPSLDNKCESKGYIPVPGSLGGSWSDIEQESFILGLYIFGKNLIQVQRFVGSKDMGDVQSFYYGKFYRSEGHRRWSECRKMRSRRCIHGQRIFTGWRQHELLSRLLPHMSEESGNTLHETLGEGKVSLEEYVSTLKAMVGLNILVEAVGVGKGKHDLTGVAMEPVKANPPISTRSELPVGKACSSLSSAEIIKFLTGDFRLSKARSNDLFWEAVWPRLLASGWHSEQPKNNGYATSKASLVFLIPGIKKFSRRKLVKGNHYFDSVSDVLNKVAADPMLLEFEVEAVHGDRMKEENGPKNPSKERDDNDSSEDEPADEPASADKISNDQEDSFPTTFDDKKGMLIDGLDYAINLSKQGTVVGGLHDNCEDRYPDLLNKQHPRKSIKRQFSRRVESVRPKYLSPILKRRRLNACNREESRRCTNALPTGPHLNEEERQWQSHSLEASNTVVTEVVGPSQPKVSASSSGKGSADGSSGCILSENGFSISTVSETVSHDKPQKRALIDLNLPHLLPDFETDGPFIEAADSQEDFSTKGSSFPPESNQGHEDSWAPVTSNGMDSADLPVANSRRQSTRNRPLTTRVLEALECGFFNTRRRGRGTKAQPRGNLMPRPPRRRRGARDGVRVSDSGNAGTDITGFPGRWGG
>Lchi27732
MDWIIHEWAPPSYYNNNNNNNYKKKKKEREREGLPLDSQRPGDAAAQQGQPDPRIGTWHLRARSREWGTTEAVGTKVNDREFMPVGQSDTAALLYSSGMTGINKGVVLTHHNFISASLMASADQENDYLLISRWKELRQNERALGLATRFQHANSFSAVTSLILQYQHPIPVEQYDSARPSRATSSSVVSVLSASPSFSEAMTPTTGVSFLFGSYDSNYGFQFIMTHQRYYYAYRQPV
>Lchi05053
MDAINDYIYRSKLPNIDIPAHLPLHSYCFQNMAQFQSKPCLINGATGDIYTYEEVDLIARKVAAGLDKIGIEQGHVIMLLLPNSPEFVFAFLGASHRGAMATTANPFYTANEIAKQARACSPRLIITQACYVEKVRDLAHGNDVKIMCIDSPPEGCLHFSELMEADENNIPAVDISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIVALMELAEKYKISIAPFVPPIVLAIAKSPVVDDYDLSSIRTVMSGAAPMGKELEDAVRAKLPNATLGQGYGMTEAGPVLSMCLAFAKDPFQIKSGSCGTVVRNAELKIVDPETGASLPRNQAGEICIRGAQIMKGYLNDPESTKKTIDKDGWLHTGDVGLVDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLINNHDIADAAVVPMKDYLTGEIPVAFVVRSNGSKITEEEIKQYIAKQVVFYKKIHRVFFVDAIPKAPSGKILRKDLRAKLAAGFPN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University