Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Lindenbergia philippensis
Species name
Lindenbergia philippensis is a species of eudicot in the family Orobanchaceae.
Species info
Gene sequence info
Lindenbergia_philippensis.COMT.fa
Download
>Liphi.01G200300.1.v1.1
MNSSSLSSSSSSQDEACLHAMRLVTASVLPSALKCAVELDLLEHIKKSGGRPISPAELAAQIVATNPAADAVLDRILRLLAANDILNCSLGEAADGGVERRYSLAPICEFLTRNQDGVSVAPLLLMNQDKVLMEAWYHLKDAVLDGGIPFNKAHGMSAFEYPAKDPRFNRVFNQGMSQQSTLLMKKILDVYKGFEGLKTLVDVGGGIGASIKMILSKYPSMKGINFDLPHVIQDAPSHPGLEHISGDMFVSVPKGDAIFMKWICHDWSDAHCLKILKNCHESLPENGKVIIAERILSEMPNTAQSSLLGFTVDVMMLAFNPGGKERTEKEFHTLAKESGFKEFRKVCSAFGIWIMELYK
>Liphi.01G200400.1.v1.1
MQLASSSVLPMVLKSAIELNLLELIKKKAGPTAAFVSPAELAAEIPAAATNPTAALDRILYFLAANSVLNCRLDRRPDGGVERRYSLAPVCKFLTRNENGVSMAPMLLMMQDKVIMGSWYHLKDAILEGELPFNKAYGMSALEYMEKDPRFNNLFNQAMSNPSMMFMKKILEINHGFEGLKSMVDVGGGIRSTLNMIISKYPSIKGTNFDLPHVFLSAASYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEQYLKFMKNCYQALPENGKLIWAEFVLPEVPDNGLPTKSVANIDLLMMAQTPGGKERTEMEFQTLAKNAGFTDIHQVCPGSQYLDNGAL
>Liphi.01G200100.1.v1.1
MDSNSKKPITSLMDQKISEEEEEANFLFAMQLTSGSVLPMVLKAAIELDLLELIKRAEPASAGELAARLPTRNPDAVAMVDRILRLLAAHGVLTASLEPTSGGGVERRYGLAPVCRFLTRNEDGVSVGPGSVLIQDKVLMETWYHLKDAVLEGGVPFDRAYGMNAFEYPAKDPRFNKIFNQAMFEQSTIFMKKILEKYQGFEGLQSLVDVGGGIGASLKMIISKYPLIKGINYDLPHVIQDAPFYPGVEHIGGDMFVSVPQADAIFMKWICHDWSDEHCKKLLKNCYEALPENGKVIIADSIFPEDTNSGLAYSCVAQSDVLMLAYNPGGKERSEKEFWALAQYAGFKQLVKVCSAFNIWIMELRK
>Liphi.01G200200.1.v1.1
MPNTEQSASIGFTVDVIMLAYNPGGKERTEKEFHALAKEAGFKEFRKVCCAFTIWIMELHK
>Liphi.05G091900.1.v1.1
MDTISSNHDYIKHGEDNEACVAALAACVSHIFPKALSAAIQLDLFKIIARAGGGARLSASDIASRLPITAIIDIGALDSILGLLTAHSLLTCSIPKAEHGTIERRYELAPAGKFFVGDGERVSLAPFQAYLSRGDLPGLVQRLIEGRNSFVKSHGKSLYEFMESDHESGKVFDDAMGAHSSVLMNKAVKVYNGFEGLSSLVNVGGGNGATLDIIISNYPSIRGINFDLPQVVQYAPSYNGIEHIAGDMFLEIPKGDAILLKFVLHNWGDDQCRNILKNCCKALPNKGKLIIMDSILPSIPQNDVHAKYVLQMDLIMSAVLGGKERTKDEIEALAKEAGFGEFKVVCYVYGIWIMESIKLG
>Liphi.07G037000.1.v1.1
MFLSVPKGDAIFMKWICHNWSDDQCLKLLKNCYEAIPENGKVILAEFILPEFPDNGLPAKNAFLLDWAIMANCPGGKERTEKEFHTLATGAGFKEFNKVCCVHSFWILELRCSALAEHGNKVVCILGVVLWLYKWVLGVLGRKIR
>Liphi.14G115300.1.v1.1
MGSTTKHDAISAVDSPSSDEESCLFAMQLASASVLPMVLKAAIELDLLELIKQAGSGGALVSPAQLAARLPTANPEAPVMLDRILRLLASYSVLDCRLETRPDGGVELLYGLAPVCKFLTKNEDGVSMAALLLMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFEYHGKDLRFNKVFNQGMSNHSTILMKKILEIYHGFEGLKSVVDVGGGTGATLDMIISKHTSIKGINFDLPHVIDDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLNFLKNCYEALPENGKVILAECILPEVPDTGLATQNVVHVDVIMLAHNPGGKERTEKEFQSLAKGAGFKEFQKVCCAYNVWIMELRK
MNSSSLSSSSSSQDEACLHAMRLVTASVLPSALKCAVELDLLEHIKKSGGRPISPAELAAQIVATNPAADAVLDRILRLLAANDILNCSLGEAADGGVERRYSLAPICEFLTRNQDGVSVAPLLLMNQDKVLMEAWYHLKDAVLDGGIPFNKAHGMSAFEYPAKDPRFNRVFNQGMSQQSTLLMKKILDVYKGFEGLKTLVDVGGGIGASIKMILSKYPSMKGINFDLPHVIQDAPSHPGLEHISGDMFVSVPKGDAIFMKWICHDWSDAHCLKILKNCHESLPENGKVIIAERILSEMPNTAQSSLLGFTVDVMMLAFNPGGKERTEKEFHTLAKESGFKEFRKVCSAFGIWIMELYK
>Liphi.01G200400.1.v1.1
MQLASSSVLPMVLKSAIELNLLELIKKKAGPTAAFVSPAELAAEIPAAATNPTAALDRILYFLAANSVLNCRLDRRPDGGVERRYSLAPVCKFLTRNENGVSMAPMLLMMQDKVIMGSWYHLKDAILEGELPFNKAYGMSALEYMEKDPRFNNLFNQAMSNPSMMFMKKILEINHGFEGLKSMVDVGGGIRSTLNMIISKYPSIKGTNFDLPHVFLSAASYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEQYLKFMKNCYQALPENGKLIWAEFVLPEVPDNGLPTKSVANIDLLMMAQTPGGKERTEMEFQTLAKNAGFTDIHQVCPGSQYLDNGAL
>Liphi.01G200100.1.v1.1
MDSNSKKPITSLMDQKISEEEEEANFLFAMQLTSGSVLPMVLKAAIELDLLELIKRAEPASAGELAARLPTRNPDAVAMVDRILRLLAAHGVLTASLEPTSGGGVERRYGLAPVCRFLTRNEDGVSVGPGSVLIQDKVLMETWYHLKDAVLEGGVPFDRAYGMNAFEYPAKDPRFNKIFNQAMFEQSTIFMKKILEKYQGFEGLQSLVDVGGGIGASLKMIISKYPLIKGINYDLPHVIQDAPFYPGVEHIGGDMFVSVPQADAIFMKWICHDWSDEHCKKLLKNCYEALPENGKVIIADSIFPEDTNSGLAYSCVAQSDVLMLAYNPGGKERSEKEFWALAQYAGFKQLVKVCSAFNIWIMELRK
>Liphi.01G200200.1.v1.1
MPNTEQSASIGFTVDVIMLAYNPGGKERTEKEFHALAKEAGFKEFRKVCCAFTIWIMELHK
>Liphi.05G091900.1.v1.1
MDTISSNHDYIKHGEDNEACVAALAACVSHIFPKALSAAIQLDLFKIIARAGGGARLSASDIASRLPITAIIDIGALDSILGLLTAHSLLTCSIPKAEHGTIERRYELAPAGKFFVGDGERVSLAPFQAYLSRGDLPGLVQRLIEGRNSFVKSHGKSLYEFMESDHESGKVFDDAMGAHSSVLMNKAVKVYNGFEGLSSLVNVGGGNGATLDIIISNYPSIRGINFDLPQVVQYAPSYNGIEHIAGDMFLEIPKGDAILLKFVLHNWGDDQCRNILKNCCKALPNKGKLIIMDSILPSIPQNDVHAKYVLQMDLIMSAVLGGKERTKDEIEALAKEAGFGEFKVVCYVYGIWIMESIKLG
>Liphi.07G037000.1.v1.1
MFLSVPKGDAIFMKWICHNWSDDQCLKLLKNCYEAIPENGKVILAEFILPEFPDNGLPAKNAFLLDWAIMANCPGGKERTEKEFHTLATGAGFKEFNKVCCVHSFWILELRCSALAEHGNKVVCILGVVLWLYKWVLGVLGRKIR
>Liphi.14G115300.1.v1.1
MGSTTKHDAISAVDSPSSDEESCLFAMQLASASVLPMVLKAAIELDLLELIKQAGSGGALVSPAQLAARLPTANPEAPVMLDRILRLLASYSVLDCRLETRPDGGVELLYGLAPVCKFLTKNEDGVSMAALLLMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFEYHGKDLRFNKVFNQGMSNHSTILMKKILEIYHGFEGLKSVVDVGGGTGATLDMIISKHTSIKGINFDLPHVIDDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLNFLKNCYEALPENGKVILAECILPEVPDTGLATQNVVHVDVIMLAHNPGGKERTEKEFQSLAKGAGFKEFQKVCCAYNVWIMELRK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University