Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Ammopiptanthus nanus
Species name
Ammopiptanthus nanus is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Ammopiptanthus_nanus.4CL.fa
Download
>EVM0022028.1_R0
MISVDTQHTPELSAPKTCTPNTDQNQPCPQTQTTHVFKSKLPDIPISNHLPLHTYCFEKLSEFADRPCLIVGSAGKTYTYADTHLLSRKIAAGLSNLGINKGDVIMILLQNSAEFVFSFIAASMIGAVATTANPFYTSAEIFKQLTVSKAKLIITQSMYVDKLRQQDNTKVGEDFKVITVDDPPENCLHFSVISEGNENEVPEVEIDPDDAVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLKDEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMHKFEIAALLELIQRYKVSVAMVVPPLVLALTKNPMVAEFDLSSIRLVLSGAAPLGKELEEALHTRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVVDSETGVSLAYNQPGEICIRGQQIMKGYLNDEKATAATIDGDGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLETATQTPYRV*
>EVM0000816.1_R0
MNQPPKLAMYIFRSKLPDIPISNNLIPLHTDCFPTRRPSISPPECPTSASSKPFYTAAEITKQLTASKAKLIITHSVHVEKLRGFKVITVDDPPENCMHFSVVSEADESEVPEVEIHPVALPFSSGTTGLPKGVVLTHKSLITGVAQMVCTYLRVISLMIDKLYTFHPFFLNQFTRMLLLLMLIYFRVLLMMAKFEIRALLELIERHRVSVAMVVPPLVLALAKNPTVGDYDLSSIRVVMSGAAPLGKELEDALRSRLPHAVLGQGYGMTEAGPVLSMCLGFAKYPIPTKSGSCGTVVRNAELKVIHPQSGFSLSYNQPGEICIRGQQIMKGYLNDEKATSATIDGDGWLHTGDIGYIDDDDEVFIVDRVKELIKFKGFQVPPAELEGLLLSHPSIVDAAVVPQKDAAAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYRRLHEVYFVHAIPKSPSGKILRKDLKEKLASTTQMA*
>EVM0006415.1_R0
MQRSGYGRDGIYRSLRPSLHLPNDPNLSLVSFLFNTTLSSFSTKTALIDADDSSQSLSYAHLKSKVAKLAHAFLHHLAINKNDVVFLFASNSIHFPLCFLAATAIGAVVSTANPIYTVSEVSKQVKDSNPKLVITVPELWDKAKDFNLPTVLLGSQSKTHVASSANITTLNELMELPGSSTELPVNDVKQSDTATLLYSSGTTGVSKGVVLTHGNFIAASLMVGMDDDVAGEKDDVFLCVLPMFHVFGLAIIVYSQLRRGNTVVSLRRFEFEVFLKTIDKYKVTNLWLVPPIVLALAKRSLVKKYDLSSLKRIGSGAAPLGKELMEECARRFPHVTVCQGYGMTETCGIVSLENPRVGIRHTGSTGMLVSGVEAQIVSVDSHKPLPPRQLGEICVRGPNMMQGYHNNPQATRSTVDKKGWVHTGDLGYFDEEGQLYVVDRIKELIKYKGLQVAPAELEGLLISHPEILDAVVVPYPDDEAGEVPIAYVVRSPNSSLTEEQVQKFIANQVAPFKRLRKVTFISSVPKTASGKILRRELIEKTRSKI*
>EVM0017009.1_R0
MGTCIENFVQGEEEHIFRSRYSPVPVPDNVTLPEFVLQHAELYADKVAFVDAVTGKRITYSELVRDTHRFSKALRSIGLRKGHVVIVVLPNVIEYAIIALGIMAAGGVFSGANPTSHASEIKKQAQSADAKLIVTNSANYEKLKGLGLPVIVLADELVEGAMNWNKLLEAADHAGDVTKEPIQQNDLCAMPFSSGTTGMAKGVMLTHRNLVANLCSTLFGVGPELMGQVTTLGLIPFFHIYGTTGICCATIRNKGKVVVMGRFELKTFLNALIAHEVTFAPIVPPIILSLVKNPIVDEFDLSKLKLQAIMTAAAPLAPELLTAFEHKFPGVVIQEAYGLTEHSCITLTHAQKGLGNPQKNSVGFILPNLEVKFIDPDTGRSLPRNTPGELCVRSQCVMQGYYKQVDETAQTIDKNGWLHTGDIGFIDDEENVFIVDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAASVVLSEGARESEEDIMNHVASNVAHYKKVRVVHFVEAIPKSPSGKIMRRLIKEKMVEKMKTNSTTKSNNF*
>EVM0020960.1_R0
MQRSSSSSGYGSDGIYGSPRPPLVLPNNPNLSLVTHFFSKVSSFPTKTALIDADSSLSLTFSHFNSLTVKLSHAFLHLGITKNDVVLFLSPNTIYYPICFLALAAIGAVSSTVNPTYTAAEISKQVKDSNPKLVITVPELWNKVKNFNLPAVILGSHKVESDSKIITFNELVELAGDPTEFPTNNNVKQSDTAALLYSSGTTGVSKGVVLTHGNFIAASIMIGMDDEIDGQGQMHDVFLCVLPMFHVFGLTVITYSQLQRGNAVVSLNRFEFEVVLKTIEKYRVTHLWVVPPIILALAKHGLVDKYDLSSLKHIGSGAAPLGKDLMKECATRFPHATVTQGYGMTETCGIVSLENSRVGVRHTGSAGLLVSGVEAQIVSVDTLKPLPPRQLGEIWVRGPNMMQGYHNNPQATRLTIDKKGWVHTGDLGYFDEDGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPIAYVVRSSSSSLTEEDVQKFIANQVAPFKRLRRVTFINSVPKTASGKILRRELIDKARSKI*
>EVM0001200.1_R0
MAIESTKQQQQQHNNNKNKNDEEEFIFRSKLPDIYIPNHLPLHSYCFEKLSDEFGSRPCLIDAPTGDMYTYHDVHLTARKVASGLNKLGVQQGHVIMLLLPNSPEFVFAFLGASYRGAITTAANPFFTPAEIAKQAKASNAKLLITQSSYYDKVKDLSSDVKLVFVDTTNTTIPPAPAEGEGHHHFSELAEADENEMAEVKIEGDDVVALPYSSGTTGLPKGVMLTHKGLVSSIAQQVDGENPNLYFHEEDVILCVLPLFHIYSLNSVLLCGLRAKASILLMPKFEIKGLLGLIQKHRVTIAPLVPPIVLAIANSQHLQNYDLSSIRVLKSGGAPLGKELEHTLRAKFPNAKLGQGYGMTEAGPVLTMCLAFAKEPIDVKPGACGTVVRNAEMKIVDPETGNSLPRNQSGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPKISDAAVVPMKDEAAGEVPVAFVVTSNGYTDTTEDEIKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGVPN*
>EVM0034543.1_R0
MTSAKKLKLTCNLCIMSSLFCVHSVWLRRGRSRATPTPPPCEEFVFHYKLPIHSYCFQNLSHFQHRPCLINADIGDTLTYADIHLTACKIASTTDPSSPSPSLGPLVVAMPSPPLTPSTRWQSWQSKRRA*
>EVM0029687.1_R0
MAPPPPPQEFIFRSKLPDIPIPTLLPLHSYCFQNLSHFQHRPCLINADTGDTLTYAEVDLTARRIAAGLHKIGIRQGDVIMLILRNCPQFALAFLGASHRGCAVTTANPFYTAAELEKQARDTKAKLIITQAAYVEKIKGFAENKDAMVMCIDSSEDQEDVLHFSVLTHADERGAPNVNINPDDVVALPYSSGTSGLPKGVMLTHKNLVTSVAQLVDGENPNQYTHSEDVLLCVLPMFHIYALNSILLCGIRAGAAVLIVHKFEITPLLEMMEKYKVTIASFVPPIVLALVKSGDAQRYDLSSIRMVITGAAPMGVELEEAVKARLPHAILGQGYGMTEAGPLSISLAFAKEPFKIKSGACGTPVRNAEMKIVDTETGASLPRNKTGEICIRGTKVMKGYLNDPEATERTIDKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVPLKDEVAGEVPVAFVVRSNGSKITEDEIKQYVSQQVVFYKRINRVFFTDTIPKGASGKILRKELSARLTECLVAN*
>EVM0022478.1_R0
MAIENETKQQKRDIIFRSKLPDIYIPKHLPLHSFCFENLSQFGARPCLINAPTGEIYTYYDVELTARRVASGLNKLGIQQGEVIMLLLPNTPEFVFAFLGASFLGAITTAANPFFTSSEIAKQAKASKAKLLITQACYYEKVKDLDVKVKLMFVDSPPSVAEGHLHFSELGLADENEMPQVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHTEDVILCVLPLFHIYSLNSVLLCGLRAKAAILLMPKFDINGLLGLIQKHRVSIAPVVPPIVLAIAKSPDLDNYDLSSIRVLKSGGAPLAKELEHTVRAKFPNAKLGQGYGMTEAGPVLSMCLIFAKEPVDVKPGACGTVVRNAEMKIVDPETDNSLPRNQPGEICIRGDQIMKGYLNDPEATKRTIDKEGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPKISDVAVVPMKDEAAGEVPVAFVVRSNGDIDTTEDEIKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRTKLAAGVPN*
MISVDTQHTPELSAPKTCTPNTDQNQPCPQTQTTHVFKSKLPDIPISNHLPLHTYCFEKLSEFADRPCLIVGSAGKTYTYADTHLLSRKIAAGLSNLGINKGDVIMILLQNSAEFVFSFIAASMIGAVATTANPFYTSAEIFKQLTVSKAKLIITQSMYVDKLRQQDNTKVGEDFKVITVDDPPENCLHFSVISEGNENEVPEVEIDPDDAVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLKDEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMHKFEIAALLELIQRYKVSVAMVVPPLVLALTKNPMVAEFDLSSIRLVLSGAAPLGKELEEALHTRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVVDSETGVSLAYNQPGEICIRGQQIMKGYLNDEKATAATIDGDGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLETATQTPYRV*
>EVM0000816.1_R0
MNQPPKLAMYIFRSKLPDIPISNNLIPLHTDCFPTRRPSISPPECPTSASSKPFYTAAEITKQLTASKAKLIITHSVHVEKLRGFKVITVDDPPENCMHFSVVSEADESEVPEVEIHPVALPFSSGTTGLPKGVVLTHKSLITGVAQMVCTYLRVISLMIDKLYTFHPFFLNQFTRMLLLLMLIYFRVLLMMAKFEIRALLELIERHRVSVAMVVPPLVLALAKNPTVGDYDLSSIRVVMSGAAPLGKELEDALRSRLPHAVLGQGYGMTEAGPVLSMCLGFAKYPIPTKSGSCGTVVRNAELKVIHPQSGFSLSYNQPGEICIRGQQIMKGYLNDEKATSATIDGDGWLHTGDIGYIDDDDEVFIVDRVKELIKFKGFQVPPAELEGLLLSHPSIVDAAVVPQKDAAAGEVPVAFVVRSNGFDLTEEAVKEFIAKQVVFYRRLHEVYFVHAIPKSPSGKILRKDLKEKLASTTQMA*
>EVM0006415.1_R0
MQRSGYGRDGIYRSLRPSLHLPNDPNLSLVSFLFNTTLSSFSTKTALIDADDSSQSLSYAHLKSKVAKLAHAFLHHLAINKNDVVFLFASNSIHFPLCFLAATAIGAVVSTANPIYTVSEVSKQVKDSNPKLVITVPELWDKAKDFNLPTVLLGSQSKTHVASSANITTLNELMELPGSSTELPVNDVKQSDTATLLYSSGTTGVSKGVVLTHGNFIAASLMVGMDDDVAGEKDDVFLCVLPMFHVFGLAIIVYSQLRRGNTVVSLRRFEFEVFLKTIDKYKVTNLWLVPPIVLALAKRSLVKKYDLSSLKRIGSGAAPLGKELMEECARRFPHVTVCQGYGMTETCGIVSLENPRVGIRHTGSTGMLVSGVEAQIVSVDSHKPLPPRQLGEICVRGPNMMQGYHNNPQATRSTVDKKGWVHTGDLGYFDEEGQLYVVDRIKELIKYKGLQVAPAELEGLLISHPEILDAVVVPYPDDEAGEVPIAYVVRSPNSSLTEEQVQKFIANQVAPFKRLRKVTFISSVPKTASGKILRRELIEKTRSKI*
>EVM0017009.1_R0
MGTCIENFVQGEEEHIFRSRYSPVPVPDNVTLPEFVLQHAELYADKVAFVDAVTGKRITYSELVRDTHRFSKALRSIGLRKGHVVIVVLPNVIEYAIIALGIMAAGGVFSGANPTSHASEIKKQAQSADAKLIVTNSANYEKLKGLGLPVIVLADELVEGAMNWNKLLEAADHAGDVTKEPIQQNDLCAMPFSSGTTGMAKGVMLTHRNLVANLCSTLFGVGPELMGQVTTLGLIPFFHIYGTTGICCATIRNKGKVVVMGRFELKTFLNALIAHEVTFAPIVPPIILSLVKNPIVDEFDLSKLKLQAIMTAAAPLAPELLTAFEHKFPGVVIQEAYGLTEHSCITLTHAQKGLGNPQKNSVGFILPNLEVKFIDPDTGRSLPRNTPGELCVRSQCVMQGYYKQVDETAQTIDKNGWLHTGDIGFIDDEENVFIVDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAASVVLSEGARESEEDIMNHVASNVAHYKKVRVVHFVEAIPKSPSGKIMRRLIKEKMVEKMKTNSTTKSNNF*
>EVM0020960.1_R0
MQRSSSSSGYGSDGIYGSPRPPLVLPNNPNLSLVTHFFSKVSSFPTKTALIDADSSLSLTFSHFNSLTVKLSHAFLHLGITKNDVVLFLSPNTIYYPICFLALAAIGAVSSTVNPTYTAAEISKQVKDSNPKLVITVPELWNKVKNFNLPAVILGSHKVESDSKIITFNELVELAGDPTEFPTNNNVKQSDTAALLYSSGTTGVSKGVVLTHGNFIAASIMIGMDDEIDGQGQMHDVFLCVLPMFHVFGLTVITYSQLQRGNAVVSLNRFEFEVVLKTIEKYRVTHLWVVPPIILALAKHGLVDKYDLSSLKHIGSGAAPLGKDLMKECATRFPHATVTQGYGMTETCGIVSLENSRVGVRHTGSAGLLVSGVEAQIVSVDTLKPLPPRQLGEIWVRGPNMMQGYHNNPQATRLTIDKKGWVHTGDLGYFDEDGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPIAYVVRSSSSSLTEEDVQKFIANQVAPFKRLRRVTFINSVPKTASGKILRRELIDKARSKI*
>EVM0001200.1_R0
MAIESTKQQQQQHNNNKNKNDEEEFIFRSKLPDIYIPNHLPLHSYCFEKLSDEFGSRPCLIDAPTGDMYTYHDVHLTARKVASGLNKLGVQQGHVIMLLLPNSPEFVFAFLGASYRGAITTAANPFFTPAEIAKQAKASNAKLLITQSSYYDKVKDLSSDVKLVFVDTTNTTIPPAPAEGEGHHHFSELAEADENEMAEVKIEGDDVVALPYSSGTTGLPKGVMLTHKGLVSSIAQQVDGENPNLYFHEEDVILCVLPLFHIYSLNSVLLCGLRAKASILLMPKFEIKGLLGLIQKHRVTIAPLVPPIVLAIANSQHLQNYDLSSIRVLKSGGAPLGKELEHTLRAKFPNAKLGQGYGMTEAGPVLTMCLAFAKEPIDVKPGACGTVVRNAEMKIVDPETGNSLPRNQSGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPKISDAAVVPMKDEAAGEVPVAFVVTSNGYTDTTEDEIKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGVPN*
>EVM0034543.1_R0
MTSAKKLKLTCNLCIMSSLFCVHSVWLRRGRSRATPTPPPCEEFVFHYKLPIHSYCFQNLSHFQHRPCLINADIGDTLTYADIHLTACKIASTTDPSSPSPSLGPLVVAMPSPPLTPSTRWQSWQSKRRA*
>EVM0029687.1_R0
MAPPPPPQEFIFRSKLPDIPIPTLLPLHSYCFQNLSHFQHRPCLINADTGDTLTYAEVDLTARRIAAGLHKIGIRQGDVIMLILRNCPQFALAFLGASHRGCAVTTANPFYTAAELEKQARDTKAKLIITQAAYVEKIKGFAENKDAMVMCIDSSEDQEDVLHFSVLTHADERGAPNVNINPDDVVALPYSSGTSGLPKGVMLTHKNLVTSVAQLVDGENPNQYTHSEDVLLCVLPMFHIYALNSILLCGIRAGAAVLIVHKFEITPLLEMMEKYKVTIASFVPPIVLALVKSGDAQRYDLSSIRMVITGAAPMGVELEEAVKARLPHAILGQGYGMTEAGPLSISLAFAKEPFKIKSGACGTPVRNAEMKIVDTETGASLPRNKTGEICIRGTKVMKGYLNDPEATERTIDKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVPLKDEVAGEVPVAFVVRSNGSKITEDEIKQYVSQQVVFYKRINRVFFTDTIPKGASGKILRKELSARLTECLVAN*
>EVM0022478.1_R0
MAIENETKQQKRDIIFRSKLPDIYIPKHLPLHSFCFENLSQFGARPCLINAPTGEIYTYYDVELTARRVASGLNKLGIQQGEVIMLLLPNTPEFVFAFLGASFLGAITTAANPFFTSSEIAKQAKASKAKLLITQACYYEKVKDLDVKVKLMFVDSPPSVAEGHLHFSELGLADENEMPQVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHTEDVILCVLPLFHIYSLNSVLLCGLRAKAAILLMPKFDINGLLGLIQKHRVSIAPVVPPIVLAIAKSPDLDNYDLSSIRVLKSGGAPLAKELEHTVRAKFPNAKLGQGYGMTEAGPVLSMCLIFAKEPVDVKPGACGTVVRNAEMKIVDPETDNSLPRNQPGEICIRGDQIMKGYLNDPEATKRTIDKEGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPKISDVAVVPMKDEAAGEVPVAFVVRSNGDIDTTEDEIKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRTKLAAGVPN*
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University