Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Leavenworthia alabamica
Species name
Leavenworthia alabamica is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Leavenworthia_alabamica.COMT.fa
Download
>LA_scaffold241_8.mRNA1
MGSTVETQITPVQVTDDEAALFAIQLASASVLPMALKTALELDILEIMAKNSSPMSPTEISSHLPTKNPQAPVMLDRILRLLASYSVLTCSTRTFNDGVERFYGLGPVCKYLTKNEDGVSIAALCLMNQDKVLMESWYHLKDAILDGGIPFNKAYGMSAFEYHGTDPRFNKVFNSGMSNHSTITMKKLLETYKGFESLTSLVDVGGGIGATLKMIVSKYPKLKGINFDLPHVIEVAPSHPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCVKVLKNCYESLPEDGKVILAECILPETPDLSLSTKQVVHVDCIMLAHNPGGKERTEKEFEALAKGSGFKGIKVVCDAFGVHVIELLKKL
>LA_scaffold573_132.mRNA1
MERESSESRNKSRLAIMELANMISVPMSLNAAVRLGIADVIWNNGTNSPLSAAEILPRLLLSSNTTNNGDPENLQRILRMLTSYNVFSEHLVGTIERKYSLTDVGKTLVTDSNGFSYAAYVLQHHQEALMRAWPLVHTAVMEPETEPYVKANGEAAYEQYGKNEEMNNLMQKAMSGVSVPFMKAILDGYDGFKSVVHLVDVGGSAGDCLRMILQQFPNIHEGINFDLPEVIAKAPIIPGVTHISGDMFQSVPNGDAIFMKWVLTTWTDEECKKIMKNCYNALPVGGKLIACEPVLPKETDDSHRTRALLEGDIFVMTIYRTKVCSQIFPAFQKLSKSFSKQLKFVYADIDECPETTRHIRYTPTFQFYRDGEKVDEMFGAGEERLHDRLWLHS
>LA_scaffold809_6.mRNA1
MNSLQSSKGSSNEEEDILLTIQLGVLNLVPYATKTATDLYLFETMAKARPLGTYLSPLDLASTAAPKNPNAPMMIDRLLRFLVAYSVCTCKLVKNKEGRECRVYGLGKVGKNLIKDEDGFSLATYVLESFSKAKEDVWSYLTNSIQEGGASALERAKGASLFEYMKDDEKAKKSFTEAMMNHTSIVMKKILKSYDGFEGISDLVDVGGCLGSNLAQITSKFPHINGVNFDLPHIIKEAPIIHGVEHIAGDMFDEVPQGQAIMMKFILHDWSDEICVEILKNCKKAIPEHGKVIVIEMIVPQEVSDTDLATKNTLCLDLKMLCFTSGGKERTKDEFEDLAIKAGFKPPKIIYGAYSYWILELYPN
>LA_scaffold867_22.mRNA1
MGSTAETQITPVQVSDDEGALFAMQLASASVLPMALKSALELDLLEIMAKNSSPMSPSEIASSLPTKNPEAPVMLDRVLRLLASYSILTCSTRTLTCGAVERIYGLGPVCKYLTKNEDGVSIAALCLMNQDKVLMESWYHLKDAILDGGIPFNKAYGMSAFEYHGTDPRFNKVFNNGMSNHSTIIMKKLLDTYKGFESLTSLVDVGGGIGATLKMIVSKYPQLKGINFDLPHVIEDAPSHPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCVKFLKNCYEALPEDGKVILAECILPEIPDSSLSTKQVVHVDCIMLAHNPGGKERTEKEFEALAKGSGFKGINRIEFSRMMSIFSPFDAFYAESSGFKMIFSDSQKQSSGVNQSPAKESQQNSGRALISLNDEKNNKKTKIQPMRIAPELDGLHCFETILPF
>LA_scaffold1088_6.mRNA1
METQITPEQVTDDEAAIFAMQLASSSVLPMALKSALELDLLEIMAKNSSTMSPSEIASHISTKNIKAPIMLDRILRLLAAYSILTCSVRTLPGGGDDVERIYGLGPVCKYLTKNKDGTSFADICLTTQDKGSMECWYHLTDAVLEGGIPLNKAYGMGFFEYLGTYPKFNKVFNKAMANYSTIIMKKILETYKGFEGLTSLVDVGGGIGACLKMIISKYPNIKGINFDLPHVINDAPHYPGIDNVDGDMFISVPNGDAIFMKSICHDWSDEHCIQLLKHCYKALPENGKVILAEFILPEIPDPSPLSKLVIHLDCLMMVHCGGKERTKKEFEALARESGFMEIQVICKAFGVYIIEFLKQI
>LA_scaffold1281_6.mRNA1
MGYIFEETVSSNPNSLNVIDNDNELGLMAVRIANATAFPMVLKAALELGVFDTLYIEASSTNLFLSPYEIASRLPTTPRNPEAPVLLDRMLRLLASYSMVKSGTVPVGKGERGYRAEPICRFFLKDNIQDIGSLASQVIVNTNNVFLNTWAQLKDVVLEGGDAFGRAHGGMKLFDYMGTDERFSKLFNQTGFTIAVVKKALEVYKGFKGVDVLVDVGGGVGNTLGVVTSKHPDIKGINFDLPCALAQAPSYPGVEHVPGDMFVDVPTGDAMILKRILHDWTDEDCVKILKNCWKSLPDNGKVVVIELVTPDDAENGDINANIAFDMDMLMFTQCSGGKERSRAEFEALAVASGFTHCKFVCQAYHCWVIEFCK
>LA_scaffold1281_7.mRNA1
MGYLSNEILSPNSKTPNVIDDDNELGLMAVRIANATAFPMVLKAALELGVFDTLYAEAAHSNSFFSPAEIASKLPTTPRNPEAPLLLDRMLRLLASYSMVKSIKVSEGKGERLYKAEPICRFFLKNNIQDIGSLASQVIVNCDSVFLNTWAQLKDVVLEGGDAFGRAHGGMKLFDYMGTDERFSKLFNQTGFTIAVVKKALEVYKGFKSVDVLVDVGGGVGNTLGVVTSKYPNIKGINFDLPCALAQAPTYPGVEHVSGDMFVDVPTGDAMILKRILHDWTDEDCVKILKNCWKSLPKNGKVVVIELVTPDNAENGDINANIAFDMDMLMFTQCSGGKERSRAEFEALATASGFNHCNFVCQAYHCWIIEFCKENV
>LA_scaffold1302_10.mRNA1
MFARQKYGNMYFRQNYENIFFRQKYGNTFSRQKYGNTFSCQKYRNTFFREKYGNMFARQKYGNMYFRQNYENIFFRQKYGNTFSRQKYGNTFFHQKYGNTFFPPKIRKHWVLHDWGDKDCIQILKNCKEAVPPSVGKVMIVDSVIGEKKRRMIMEERDEKLEHVRLMLDMVMMAHTRRGKERTLKEWDFVLTEAGFARYEVRDIDDVQSLIIAYRS
>LA_scaffold1421_30.mRNA1
MENMPSTIYPEQKPGQTKDEQQVLKEARLLARRLSNSSAFPMVLKTALELGVIDIIASIGDGMWLSPSEIVLRLQTKPSNPQAPEFLDRMLRLLTSYSILKCRNVVIEDEGQTGKIKRVYAAEPVCKFLLNNSDGSGSFAPLVILNLSDTNINTWRHLKDVILEGKGAFSSAHGMQVFEYLRSNEQYCKVFSRAMSESSIMVMEEVLETYDGFKDVKTLVDVGGGLGNTLSLITSKYTHIMGINFDLPPVIARAPLYPRIKHVGGDMFTNIPNGDAIFMKWILHDWSDEQCVKILKNCWKSLPENGKVIIVEMVTPSEAMSEDICSNIVFGMDMTMLTLFYGGKERSLSEFEALAYTSGFSRCEIVCSVSPLFVIEMYK
>LA_scaffold1517_13.mRNA1
MGSLTETQITPSKISDEEANLFAMQLAGATVLPMVLTSALELDLLEIISKNAGVVGGQLSPSEIVSHLPSKNPDAPVMVDRILRLLASYSILTCSVRKLIDGGVERLYGLGPVCKYLTKNEDGVSLAALCHLNRDRVFMESWYHLKDAVLEGGVPFDKAFGMDAFEYQGADPRFNKVFNNGMSNHTTIVMTKILDTYKGFEGLSSLVDVGGGIGVTLRMIVSKHPHIKGILYDLSHVIEEAVSYPGIEHIGGDMFVSIPKADAIFMKWICHDWSDEHCLKFLKNCHEALPNNGKVIVAESILPVLPDSSLLTKEVVHMDCLMLAHNPGGKERTKEEFEALAKGSGFQGFQVVCKAYGTHIMEFLKKI
>LA_scaffold1911_7.mRNA1
MEEKNQSLYAMILSSSSVLPMVLNTAIDLGLFDILAESGSSSSSSSSSPSLSASKIMSLLAVKTQEPHDPSLVNRILRFLASYSIVTCSVSTDHGEPCLVYGLAPVSKYFLKNQQERGSLAPLVNLFQDKIITDMWYNLKDSVIEGGIPFNKTHGSSAVELVGRDSRFRQVFQSSMKGFNEVFMEDFLKNYNGFDGVKSLVDVGGGDGSILSRIISTFPHIIKAINFDLPSIINTSVASPGIENVAGDMFINIPKGEAIFMKWMLHGWDDEHCVKILHNCYQSLPSNGKVIVVDMVIPELPEDSLLHRSLFQFELLMMNMNPSGKERTKREFEILARRAGFSNVQVPFTALCFSVVEFHKN
>LA_scaffold2717_14.mRNA1
MSNYFQDPLITYPEPVSTKEEQEVDDKMVSLQAENIVNSLAFPMVLKAALELGVIDTLASAGNDTWLSPYEIALSFPAKPTNPEAPVLLDRMLRLLVSHSFLKCRMVEIKENGLTGQIKRVYAAEPVCKFFTKDRDGCGSLSSLFLFLHSQVIFKTWTNLKDVILEGKDAFSSAHDMRLWEYFSSNEQFFELFHRSMSESSTMVMKKVLEVYKGFENVNTLVDVGGGIGTILGLVTSKYPHIKGVNFDVAQVLSNAPFYPGVEHVSGDMFIEVPKGDAIFMKWILHDWTDEHCIKILKNCWKSLPKKEKVIIVEMITPMEPKCGDFSSNIVFGMDLLMLTQCPGGKERSITQFENLAFASGFIRCEIICHANSYSVIEFHK
>LA_scaffold3592_1.mRNA1
MGHLVPQIPQIGDDDDDTELGLAAVRLANCAAYPMVFKATVELGVIDILYAATRADVTGSSSFLTASDITTRLPTKPSNPEAPALLERMLLLLASYSMVKCQVIEGKRAFKAEPICRYFLKDDIDQEIGTLASQLVVTLDTVFLNTWAQLKDVVLEGGVAFGRANNGLKLFDYISKDERLSKLFNRTGFSVGVLKKFLQVYKGFEEVSVLVDVGGGVGDTLGFITSKYPNIKGINFDLTCAVTQAPSYPNVEHVAGDMFLDVPKGDAIILKRILHDWTDEECEKLLKNCWKSLTENGKVIVMEVVIPDETEIGDVVSNIAFDMDLLMLTQLSGGKERSRVEYEAMAINAGFAKCNFRLKCLSYAVVSHSSSTIPSLNSQQSSTVSAFALRSVSSVKFQFPIEAKKQTFNSFDDLIVNSDKPILVDYYATWCGPCQFMVPILNEVSATLKDKIQVVKIDTEQYPSIANKYKIEALPTFILFKDGQPCDRFEGALTAKQLIQRIEDSLNVKP
MGSTVETQITPVQVTDDEAALFAIQLASASVLPMALKTALELDILEIMAKNSSPMSPTEISSHLPTKNPQAPVMLDRILRLLASYSVLTCSTRTFNDGVERFYGLGPVCKYLTKNEDGVSIAALCLMNQDKVLMESWYHLKDAILDGGIPFNKAYGMSAFEYHGTDPRFNKVFNSGMSNHSTITMKKLLETYKGFESLTSLVDVGGGIGATLKMIVSKYPKLKGINFDLPHVIEVAPSHPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCVKVLKNCYESLPEDGKVILAECILPETPDLSLSTKQVVHVDCIMLAHNPGGKERTEKEFEALAKGSGFKGIKVVCDAFGVHVIELLKKL
>LA_scaffold573_132.mRNA1
MERESSESRNKSRLAIMELANMISVPMSLNAAVRLGIADVIWNNGTNSPLSAAEILPRLLLSSNTTNNGDPENLQRILRMLTSYNVFSEHLVGTIERKYSLTDVGKTLVTDSNGFSYAAYVLQHHQEALMRAWPLVHTAVMEPETEPYVKANGEAAYEQYGKNEEMNNLMQKAMSGVSVPFMKAILDGYDGFKSVVHLVDVGGSAGDCLRMILQQFPNIHEGINFDLPEVIAKAPIIPGVTHISGDMFQSVPNGDAIFMKWVLTTWTDEECKKIMKNCYNALPVGGKLIACEPVLPKETDDSHRTRALLEGDIFVMTIYRTKVCSQIFPAFQKLSKSFSKQLKFVYADIDECPETTRHIRYTPTFQFYRDGEKVDEMFGAGEERLHDRLWLHS
>LA_scaffold809_6.mRNA1
MNSLQSSKGSSNEEEDILLTIQLGVLNLVPYATKTATDLYLFETMAKARPLGTYLSPLDLASTAAPKNPNAPMMIDRLLRFLVAYSVCTCKLVKNKEGRECRVYGLGKVGKNLIKDEDGFSLATYVLESFSKAKEDVWSYLTNSIQEGGASALERAKGASLFEYMKDDEKAKKSFTEAMMNHTSIVMKKILKSYDGFEGISDLVDVGGCLGSNLAQITSKFPHINGVNFDLPHIIKEAPIIHGVEHIAGDMFDEVPQGQAIMMKFILHDWSDEICVEILKNCKKAIPEHGKVIVIEMIVPQEVSDTDLATKNTLCLDLKMLCFTSGGKERTKDEFEDLAIKAGFKPPKIIYGAYSYWILELYPN
>LA_scaffold867_22.mRNA1
MGSTAETQITPVQVSDDEGALFAMQLASASVLPMALKSALELDLLEIMAKNSSPMSPSEIASSLPTKNPEAPVMLDRVLRLLASYSILTCSTRTLTCGAVERIYGLGPVCKYLTKNEDGVSIAALCLMNQDKVLMESWYHLKDAILDGGIPFNKAYGMSAFEYHGTDPRFNKVFNNGMSNHSTIIMKKLLDTYKGFESLTSLVDVGGGIGATLKMIVSKYPQLKGINFDLPHVIEDAPSHPGIEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCVKFLKNCYEALPEDGKVILAECILPEIPDSSLSTKQVVHVDCIMLAHNPGGKERTEKEFEALAKGSGFKGINRIEFSRMMSIFSPFDAFYAESSGFKMIFSDSQKQSSGVNQSPAKESQQNSGRALISLNDEKNNKKTKIQPMRIAPELDGLHCFETILPF
>LA_scaffold1088_6.mRNA1
METQITPEQVTDDEAAIFAMQLASSSVLPMALKSALELDLLEIMAKNSSTMSPSEIASHISTKNIKAPIMLDRILRLLAAYSILTCSVRTLPGGGDDVERIYGLGPVCKYLTKNKDGTSFADICLTTQDKGSMECWYHLTDAVLEGGIPLNKAYGMGFFEYLGTYPKFNKVFNKAMANYSTIIMKKILETYKGFEGLTSLVDVGGGIGACLKMIISKYPNIKGINFDLPHVINDAPHYPGIDNVDGDMFISVPNGDAIFMKSICHDWSDEHCIQLLKHCYKALPENGKVILAEFILPEIPDPSPLSKLVIHLDCLMMVHCGGKERTKKEFEALARESGFMEIQVICKAFGVYIIEFLKQI
>LA_scaffold1281_6.mRNA1
MGYIFEETVSSNPNSLNVIDNDNELGLMAVRIANATAFPMVLKAALELGVFDTLYIEASSTNLFLSPYEIASRLPTTPRNPEAPVLLDRMLRLLASYSMVKSGTVPVGKGERGYRAEPICRFFLKDNIQDIGSLASQVIVNTNNVFLNTWAQLKDVVLEGGDAFGRAHGGMKLFDYMGTDERFSKLFNQTGFTIAVVKKALEVYKGFKGVDVLVDVGGGVGNTLGVVTSKHPDIKGINFDLPCALAQAPSYPGVEHVPGDMFVDVPTGDAMILKRILHDWTDEDCVKILKNCWKSLPDNGKVVVIELVTPDDAENGDINANIAFDMDMLMFTQCSGGKERSRAEFEALAVASGFTHCKFVCQAYHCWVIEFCK
>LA_scaffold1281_7.mRNA1
MGYLSNEILSPNSKTPNVIDDDNELGLMAVRIANATAFPMVLKAALELGVFDTLYAEAAHSNSFFSPAEIASKLPTTPRNPEAPLLLDRMLRLLASYSMVKSIKVSEGKGERLYKAEPICRFFLKNNIQDIGSLASQVIVNCDSVFLNTWAQLKDVVLEGGDAFGRAHGGMKLFDYMGTDERFSKLFNQTGFTIAVVKKALEVYKGFKSVDVLVDVGGGVGNTLGVVTSKYPNIKGINFDLPCALAQAPTYPGVEHVSGDMFVDVPTGDAMILKRILHDWTDEDCVKILKNCWKSLPKNGKVVVIELVTPDNAENGDINANIAFDMDMLMFTQCSGGKERSRAEFEALATASGFNHCNFVCQAYHCWIIEFCKENV
>LA_scaffold1302_10.mRNA1
MFARQKYGNMYFRQNYENIFFRQKYGNTFSRQKYGNTFSCQKYRNTFFREKYGNMFARQKYGNMYFRQNYENIFFRQKYGNTFSRQKYGNTFFHQKYGNTFFPPKIRKHWVLHDWGDKDCIQILKNCKEAVPPSVGKVMIVDSVIGEKKRRMIMEERDEKLEHVRLMLDMVMMAHTRRGKERTLKEWDFVLTEAGFARYEVRDIDDVQSLIIAYRS
>LA_scaffold1421_30.mRNA1
MENMPSTIYPEQKPGQTKDEQQVLKEARLLARRLSNSSAFPMVLKTALELGVIDIIASIGDGMWLSPSEIVLRLQTKPSNPQAPEFLDRMLRLLTSYSILKCRNVVIEDEGQTGKIKRVYAAEPVCKFLLNNSDGSGSFAPLVILNLSDTNINTWRHLKDVILEGKGAFSSAHGMQVFEYLRSNEQYCKVFSRAMSESSIMVMEEVLETYDGFKDVKTLVDVGGGLGNTLSLITSKYTHIMGINFDLPPVIARAPLYPRIKHVGGDMFTNIPNGDAIFMKWILHDWSDEQCVKILKNCWKSLPENGKVIIVEMVTPSEAMSEDICSNIVFGMDMTMLTLFYGGKERSLSEFEALAYTSGFSRCEIVCSVSPLFVIEMYK
>LA_scaffold1517_13.mRNA1
MGSLTETQITPSKISDEEANLFAMQLAGATVLPMVLTSALELDLLEIISKNAGVVGGQLSPSEIVSHLPSKNPDAPVMVDRILRLLASYSILTCSVRKLIDGGVERLYGLGPVCKYLTKNEDGVSLAALCHLNRDRVFMESWYHLKDAVLEGGVPFDKAFGMDAFEYQGADPRFNKVFNNGMSNHTTIVMTKILDTYKGFEGLSSLVDVGGGIGVTLRMIVSKHPHIKGILYDLSHVIEEAVSYPGIEHIGGDMFVSIPKADAIFMKWICHDWSDEHCLKFLKNCHEALPNNGKVIVAESILPVLPDSSLLTKEVVHMDCLMLAHNPGGKERTKEEFEALAKGSGFQGFQVVCKAYGTHIMEFLKKI
>LA_scaffold1911_7.mRNA1
MEEKNQSLYAMILSSSSVLPMVLNTAIDLGLFDILAESGSSSSSSSSSPSLSASKIMSLLAVKTQEPHDPSLVNRILRFLASYSIVTCSVSTDHGEPCLVYGLAPVSKYFLKNQQERGSLAPLVNLFQDKIITDMWYNLKDSVIEGGIPFNKTHGSSAVELVGRDSRFRQVFQSSMKGFNEVFMEDFLKNYNGFDGVKSLVDVGGGDGSILSRIISTFPHIIKAINFDLPSIINTSVASPGIENVAGDMFINIPKGEAIFMKWMLHGWDDEHCVKILHNCYQSLPSNGKVIVVDMVIPELPEDSLLHRSLFQFELLMMNMNPSGKERTKREFEILARRAGFSNVQVPFTALCFSVVEFHKN
>LA_scaffold2717_14.mRNA1
MSNYFQDPLITYPEPVSTKEEQEVDDKMVSLQAENIVNSLAFPMVLKAALELGVIDTLASAGNDTWLSPYEIALSFPAKPTNPEAPVLLDRMLRLLVSHSFLKCRMVEIKENGLTGQIKRVYAAEPVCKFFTKDRDGCGSLSSLFLFLHSQVIFKTWTNLKDVILEGKDAFSSAHDMRLWEYFSSNEQFFELFHRSMSESSTMVMKKVLEVYKGFENVNTLVDVGGGIGTILGLVTSKYPHIKGVNFDVAQVLSNAPFYPGVEHVSGDMFIEVPKGDAIFMKWILHDWTDEHCIKILKNCWKSLPKKEKVIIVEMITPMEPKCGDFSSNIVFGMDLLMLTQCPGGKERSITQFENLAFASGFIRCEIICHANSYSVIEFHK
>LA_scaffold3592_1.mRNA1
MGHLVPQIPQIGDDDDDTELGLAAVRLANCAAYPMVFKATVELGVIDILYAATRADVTGSSSFLTASDITTRLPTKPSNPEAPALLERMLLLLASYSMVKCQVIEGKRAFKAEPICRYFLKDDIDQEIGTLASQLVVTLDTVFLNTWAQLKDVVLEGGVAFGRANNGLKLFDYISKDERLSKLFNRTGFSVGVLKKFLQVYKGFEEVSVLVDVGGGVGDTLGFITSKYPNIKGINFDLTCAVTQAPSYPNVEHVAGDMFLDVPKGDAIILKRILHDWTDEECEKLLKNCWKSLTENGKVIVMEVVIPDETEIGDVVSNIAFDMDLLMLTQLSGGKERSRVEYEAMAINAGFAKCNFRLKCLSYAVVSHSSSTIPSLNSQQSSTVSAFALRSVSSVKFQFPIEAKKQTFNSFDDLIVNSDKPILVDYYATWCGPCQFMVPILNEVSATLKDKIQVVKIDTEQYPSIANKYKIEALPTFILFKDGQPCDRFEGALTAKQLIQRIEDSLNVKP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University