Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Leavenworthia alabamica
Species name
Leavenworthia alabamica is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Leavenworthia_alabamica.HIDH.fa
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>LA_scaffold318_22.mRNA1
MGATKLAHVTTINTNNTNIHGPVVDEVQGLIKVYKDGHVERPQVVPCVDPSLPLELGVACSDVIIDQLTNVWARLYVPMMTTKSSVSKLPLLVYFHGGGFCIGSASWLCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLIKARSDNLLALPRGANKDHPYCKPVKMKSTVMRTLVCVAEMDLLMDRNMEMCEGNEKLIKRVIYRGVGHAFHILGKSQLAQTTTLEMLCHIDTFIHNYDRL
>LA_scaffold455_3.mRNA1
MATISFSHNQSSNNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPIVSPTLHPSTKATAFDIKLSNDTSIRVYIPDSSASPSVTFPLLVYFHGGGFCVGSAAWSCYHDFLTNLAIKARCIVVSVHYRLAPEHRLPAAYDDGINVISWLVNQQISNGGHSWVSRCNLSNVFLAGDSAGANIAYQVAVRITGSGKFINTLNLKGIILIHPFFGGESRTSSEKQQHHSKSSSALTLSASDTYWRLALPRGASRDHPWCNPMVNSTSSLREAKLPTTMVFMAEFDILKDRNLEMCKVMRSHGKRVEAIVHVGVGHAFHILDNSSVSRDRIHDMLCRLHNFIHQL
>LA_scaffold496_14.mRNA1
MASTNKQVSLELLPWLVVHSDGTLERLAGTEVCPPGLDLETGVLSKDIIIESKTGLTGRIYRPESIQPGQKLPLALYFHGGAFLIASASFPCYHTSVNKLVSEANIIAVSVNYRLAPEHPLPTAYEDSWNTLHTIQTLNEPWITNYADLTRFFLLGDSAGANISHHLAFQTNQPNQTLKIKGIGMIHPYFWGTKPIGSEIKDKARKQMVDGWWEFVCPSKKGSDDPWINPFTDGSPDLEEMECERVMITVAEKDILRDRGKMYYERLVKSKWRGKVELMETKGKDHVFHIFEPECDEAMEMVRGLALFINQV
>LA_scaffold585_24.mRNA1
MESDLTSEHHHLPFIRIHKNGHVERLSGNDIVPASLDKQNNVFSKDVVYSPEHDLSVRMFLPNKSIDKKLPLLIYFHGGAYIIQSPFSPVYHNYVTEVVKNTNCLAVSVQYRRAPEHPIPAAYDDSWSAIQWIFAHSDDWIKQYADFNRVFIGGDSAGANISHHMGVRAGKEKLNPRIKGIIMIHPGFWGKDPIDEYDVQDKKIRSTIADIWEKIVSPNSVDGVNDPWINVVGSGSDISRLGCERVLVAVAGKDVFWRQGMAYVAKLKKSEWKGKIEVVEDDKEGHCFHLHNPNSEHASKMMKSFVEFIIIP
>LA_scaffold890_35.mRNA1
MPSVGVKLYSVFFKFLLKHRLQNRIQSAGDESSSDPFGVTTRPEESVAASNPLFTDGVATKDIHIDPLTSLSVRIFLPESALTPIEPINSSVYSGKARTLNNLAGSDLLIRRNSLGSSNSLLSHKLESRRNSYGCSTGSSSPKVESSDVYRGYSPSSSPKVESSDVYRGYSPSTSTKNSRKLPVMLQFHGGGWVSGSNDSVANDSFCRRMAKHCDIIVLAVGYRLAPENRLGGEVKKSEVNSHIVDAFGASMVEPWLATHADPSRCVLLGVSCGANIADYIARKAIEAGHNLDPVKVVAQVLMYPFFIGSVPTQSEIKQANSYFYDKSMSILAWKLFLPEEEFSLDHPAANPLVPGRGPPLKFMPPTLTIVAEHDWMKDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDMLLRTPQAQACAEDISIWVKKYISLRGHEFSY
>LA_scaffold1020_5.mRNA1
MDSKEIASEFLPFIRTYKNGYIERLTGTEIIQPSLDPSNDVVSKDVIYSPQHNLSVRIFLPNNSTAVTKLPLLIYIHGGAWIIESPFSPIYHNYLTKLVKSANCIAVSIQYRRAPEHPIPAAYEDAWSAIQWIFSHSNGSGNEDWINKHADFNRVFIAGDSAGGNITHHMAMRAGKEKLDRKIKGIVIVHPAFWGTDPVDEDDVQDREMRNGIAQVWELIASPNSVNGTDDPLFNVNGSGSDFSDLGCDKVLVAVAGKDVFVRQGLAYAAKLKSCEWEGTVEVVEEDDEGHVFHLQNPNSEKALMFLDKFVEFIIG
>LA_scaffold1214_46.mRNA1
MDSEIAFDYSPRFRVFKNGHIERLVTESFVPPSLNSENVVVSKDSVYSLKKNLSLRIYLPYEYIDNTGENEKIPLLIYFHGGGFIMETAFSPIYNTFLTSTVSAADCIAVSVDYRRAPEHLIPIAYEDSWDAIKWIYTDHITGTGSEDWLNKHADFGKVFLAGDSAGANIAHHMGMRAGKEKLTLSGMILCHPYFLSKALIEEMEEGPRKYMEGLWEIASGSDVEDPWINVFGSDLSRLSCGRVLVMVAGNDVLAKGGWGYVEKLEKSGWEGIVQVMESKDEDHVFHLRTSNSDNALLLLQSFVEFIKKDKTTSI
MGATKLAHVTTINTNNTNIHGPVVDEVQGLIKVYKDGHVERPQVVPCVDPSLPLELGVACSDVIIDQLTNVWARLYVPMMTTKSSVSKLPLLVYFHGGGFCIGSASWLCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLIKARSDNLLALPRGANKDHPYCKPVKMKSTVMRTLVCVAEMDLLMDRNMEMCEGNEKLIKRVIYRGVGHAFHILGKSQLAQTTTLEMLCHIDTFIHNYDRL
>LA_scaffold455_3.mRNA1
MATISFSHNQSSNNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPIVSPTLHPSTKATAFDIKLSNDTSIRVYIPDSSASPSVTFPLLVYFHGGGFCVGSAAWSCYHDFLTNLAIKARCIVVSVHYRLAPEHRLPAAYDDGINVISWLVNQQISNGGHSWVSRCNLSNVFLAGDSAGANIAYQVAVRITGSGKFINTLNLKGIILIHPFFGGESRTSSEKQQHHSKSSSALTLSASDTYWRLALPRGASRDHPWCNPMVNSTSSLREAKLPTTMVFMAEFDILKDRNLEMCKVMRSHGKRVEAIVHVGVGHAFHILDNSSVSRDRIHDMLCRLHNFIHQL
>LA_scaffold496_14.mRNA1
MASTNKQVSLELLPWLVVHSDGTLERLAGTEVCPPGLDLETGVLSKDIIIESKTGLTGRIYRPESIQPGQKLPLALYFHGGAFLIASASFPCYHTSVNKLVSEANIIAVSVNYRLAPEHPLPTAYEDSWNTLHTIQTLNEPWITNYADLTRFFLLGDSAGANISHHLAFQTNQPNQTLKIKGIGMIHPYFWGTKPIGSEIKDKARKQMVDGWWEFVCPSKKGSDDPWINPFTDGSPDLEEMECERVMITVAEKDILRDRGKMYYERLVKSKWRGKVELMETKGKDHVFHIFEPECDEAMEMVRGLALFINQV
>LA_scaffold585_24.mRNA1
MESDLTSEHHHLPFIRIHKNGHVERLSGNDIVPASLDKQNNVFSKDVVYSPEHDLSVRMFLPNKSIDKKLPLLIYFHGGAYIIQSPFSPVYHNYVTEVVKNTNCLAVSVQYRRAPEHPIPAAYDDSWSAIQWIFAHSDDWIKQYADFNRVFIGGDSAGANISHHMGVRAGKEKLNPRIKGIIMIHPGFWGKDPIDEYDVQDKKIRSTIADIWEKIVSPNSVDGVNDPWINVVGSGSDISRLGCERVLVAVAGKDVFWRQGMAYVAKLKKSEWKGKIEVVEDDKEGHCFHLHNPNSEHASKMMKSFVEFIIIP
>LA_scaffold890_35.mRNA1
MPSVGVKLYSVFFKFLLKHRLQNRIQSAGDESSSDPFGVTTRPEESVAASNPLFTDGVATKDIHIDPLTSLSVRIFLPESALTPIEPINSSVYSGKARTLNNLAGSDLLIRRNSLGSSNSLLSHKLESRRNSYGCSTGSSSPKVESSDVYRGYSPSSSPKVESSDVYRGYSPSTSTKNSRKLPVMLQFHGGGWVSGSNDSVANDSFCRRMAKHCDIIVLAVGYRLAPENRLGGEVKKSEVNSHIVDAFGASMVEPWLATHADPSRCVLLGVSCGANIADYIARKAIEAGHNLDPVKVVAQVLMYPFFIGSVPTQSEIKQANSYFYDKSMSILAWKLFLPEEEFSLDHPAANPLVPGRGPPLKFMPPTLTIVAEHDWMKDRAIAYSEELRKVNVDAPVLEYKDAVHEFATLDMLLRTPQAQACAEDISIWVKKYISLRGHEFSY
>LA_scaffold1020_5.mRNA1
MDSKEIASEFLPFIRTYKNGYIERLTGTEIIQPSLDPSNDVVSKDVIYSPQHNLSVRIFLPNNSTAVTKLPLLIYIHGGAWIIESPFSPIYHNYLTKLVKSANCIAVSIQYRRAPEHPIPAAYEDAWSAIQWIFSHSNGSGNEDWINKHADFNRVFIAGDSAGGNITHHMAMRAGKEKLDRKIKGIVIVHPAFWGTDPVDEDDVQDREMRNGIAQVWELIASPNSVNGTDDPLFNVNGSGSDFSDLGCDKVLVAVAGKDVFVRQGLAYAAKLKSCEWEGTVEVVEEDDEGHVFHLQNPNSEKALMFLDKFVEFIIG
>LA_scaffold1214_46.mRNA1
MDSEIAFDYSPRFRVFKNGHIERLVTESFVPPSLNSENVVVSKDSVYSLKKNLSLRIYLPYEYIDNTGENEKIPLLIYFHGGGFIMETAFSPIYNTFLTSTVSAADCIAVSVDYRRAPEHLIPIAYEDSWDAIKWIYTDHITGTGSEDWLNKHADFGKVFLAGDSAGANIAHHMGMRAGKEKLTLSGMILCHPYFLSKALIEEMEEGPRKYMEGLWEIASGSDVEDPWINVFGSDLSRLSCGRVLVMVAGNDVLAKGGWGYVEKLEKSGWEGIVQVMESKDEDHVFHLRTSNSDNALLLLQSFVEFIKKDKTTSI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University