Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Leavenworthia alabamica
Species name
Leavenworthia alabamica is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Leavenworthia_alabamica.CHS.fa
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>LA_scaffold600_16.mRNA1
MVSVPKACALVVSAKSIGAKVSNERSSKSKLARSMARIVNSKPWSDEVESSLSSLYPSESISRTAVLQILRLIKNPGDGLRFFDWVSNKGFSHKEQSFFLMIEFLGRARNLNIARNFLFSIEKRSNGCVKLEDRYFNSLIRSYGNAGLFQESVKLFETMKKMGISPSVVTFNSLLSILLNRGRTGMAHELFDEMRRTYGVTPDSYTFNILIRGFCKNSMVDEAFRVFKEMKLYPCDPDVITYNTIMDGLCRAGKVRIAHNVLNGMMQKATHVHPNIVSYTTLVRGYCMKQQVDEALLVFHELLSRGLKPNAVTYNTLIKGLSEAHKYDEIKEILSGKDMFTTFAPDACTFNILINAHCVAGHLDAAMMVFQEMVNMKLHPDSASFSVLIRTLCIRKEFDRAETLFNELFEKEVLLGKDGCKPLAAAYNPMFEYLCANGKTKQADKSFRQLMKRGVQDPTSYRTLIMGHCREGKFKAAYDLLVLMLRREYVPDLETYEILIDGLLKIGEAVLAHDTLQRMLRSSYLPVATTFHSVLAELVKRKCANEAFSLVRLMVETKIRQNIDFSTHAVRLLFSSGQKEKAFLVVRLLYDNGYLVKMEELLDFLCENRKLLDAHRLVLFCLEKSQTVDIGTCKTVIEGLCKHMRHSEAFSLYKELAELGKHQQQLSSHVVLRNVLERTSLKSSCAGGLSMDSLFLTFTFKMSNSGFNGVEKKLGSIPTKRFANPGKATVLALGKAFPSQVVPQDKLVEGFLRDTKCKTTTVKTRYTVLSREILDKYPELTTEGSTTIKQRLEIANEAVVEMAFEASLVCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDESMEFNDMFWAVHPGGPAILNRLETKLKLGREKLESSRRALVNYGNVSSNTILYVMEYMRDELKKKGDNAQEWGLGLAFGPGITFEGLLIRSIIT
>LA_scaffold968_8.mRNA1
MSLCVVTADHKMLSTKKTEYRGQRIMAVDVSKLNREWEAKAMEVWGQPKSKVTHLVFYTTSYRDMPGPEYYLTKLLGGTHSIHHYQYHGGFQEATVLIHFRDFANKSHINGPALVVCSAFMAQDLQRSSEKLEVTRHLSSTTNTTFHSKMVERRRSLGTIIGSSHRPVEGSSSRAITGSSHRPIVEGTSSRAIVEGSSSRAITESSHRAIVEGSLSRAITRSSHRPIVEGSSSRAIVEGSSSRAITANHAQSQRTSRLQQSIADAMGVNASDVKIKVNVNINVQADITGAQIRRERIRFG
>LA_scaffold1112_3.mRNA1
MVMGDVPSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMYLTEEFLKDNANMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWVAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
>LA_scaffold1175_18.mRNA1
MGSIDAVELGSEKKPNAGKATILAIGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILNKYPELAIEGGSTVTQRLDICNDAVTEMAVEASRVCIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKELGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPRADRPYDLVGVALFGDGAGAIIIGSDPDPICEKPLFELHTAIQNFLPDTEKIIDGKLTEEGINFKLSRELPQIIEDNVENFCKKLITKAGLVHKDYNQMFWAVHPGGPAILNRIEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESKKVKNMNEGENEWGLILAFGPGVTFEGIVARNLDV
>LA_scaffold1500_3.mRNA1
MLTLGKAFPFPSTVVSQENLVEEYLREIKCDYLSIKTSCSTCIAIEGSPTIKQRLEIANDAVLLMAYEASLVCIKEWGRAVEDITNIVYVSSSEFCLPGGDLYLSAQLGLRNEVQRVMMYFLGCYGGVTRLHVAKDIAENNRGSWVLLITSETTVMGFCPPNKAHPYDLVGAALFGDGAAALIIGTDPTESEPPFMKLHYTLQQFLPGTQGVIDGRLSEEGISFQARKIPPSEGRRQRR
>LA_scaffold1846_40.mRNA1
MVMGDTPSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKDNANMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>LA_scaffold3159_5.mRNA1
MVMGDTPSLDEIRKAQRSDGPAGILAIGTANPENHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKDNANMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSNITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSNPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSGKDGEATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
>LA_scaffold3385_1.mRNA1
MLASTRVEKQKDISTSPRRVANKGKATLLALGKAFPSNVVSQENLVEEYLREIKCDDLSIKDKLQHLCKTTTVKTRYTVMSRETMQKYPELASEGSPTIRQKLEIANDAVVKMAYEASLVCIKEWGRTVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGLTGLRVAKDIAENNLGSRVLLITSETTVLGFRPPNKARPYDLVGAALFGDGAAALIIGANPTELESPFMELHYALQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLMAKATSGSDSLKLNDIFWAVHPGGPAILNGLESKLKLKPEKLECSRQALVDYGNVSSNTIFYIMDKVRDELEKKGSEGEEWGLGLAFGPGITFEGFLIRSL
>LA_C70055_2.mRNA1
MGSIDATELCSKKKPNVGKATILAFGKAFPHQLVMQEYLVDGYLKTTKCDDPELKQKLTRLCNVLLLTFDLSFCKTTTVKTRYVVMSEEILRKYPELAVEGGSTVTQRLDICNDAVTEMAVEASKACIKNWGRSLSDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSMDRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTEEGIHFKLSRELPQIIEDNVENFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRIEKRLNLSPEKLSSSRRALMDYGNASSNSIIYVLEYMLEESKKARNMKEQENEWGLILAFGPGVTFEGIVARNLDA
MVSVPKACALVVSAKSIGAKVSNERSSKSKLARSMARIVNSKPWSDEVESSLSSLYPSESISRTAVLQILRLIKNPGDGLRFFDWVSNKGFSHKEQSFFLMIEFLGRARNLNIARNFLFSIEKRSNGCVKLEDRYFNSLIRSYGNAGLFQESVKLFETMKKMGISPSVVTFNSLLSILLNRGRTGMAHELFDEMRRTYGVTPDSYTFNILIRGFCKNSMVDEAFRVFKEMKLYPCDPDVITYNTIMDGLCRAGKVRIAHNVLNGMMQKATHVHPNIVSYTTLVRGYCMKQQVDEALLVFHELLSRGLKPNAVTYNTLIKGLSEAHKYDEIKEILSGKDMFTTFAPDACTFNILINAHCVAGHLDAAMMVFQEMVNMKLHPDSASFSVLIRTLCIRKEFDRAETLFNELFEKEVLLGKDGCKPLAAAYNPMFEYLCANGKTKQADKSFRQLMKRGVQDPTSYRTLIMGHCREGKFKAAYDLLVLMLRREYVPDLETYEILIDGLLKIGEAVLAHDTLQRMLRSSYLPVATTFHSVLAELVKRKCANEAFSLVRLMVETKIRQNIDFSTHAVRLLFSSGQKEKAFLVVRLLYDNGYLVKMEELLDFLCENRKLLDAHRLVLFCLEKSQTVDIGTCKTVIEGLCKHMRHSEAFSLYKELAELGKHQQQLSSHVVLRNVLERTSLKSSCAGGLSMDSLFLTFTFKMSNSGFNGVEKKLGSIPTKRFANPGKATVLALGKAFPSQVVPQDKLVEGFLRDTKCKTTTVKTRYTVLSREILDKYPELTTEGSTTIKQRLEIANEAVVEMAFEASLVCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDESMEFNDMFWAVHPGGPAILNRLETKLKLGREKLESSRRALVNYGNVSSNTILYVMEYMRDELKKKGDNAQEWGLGLAFGPGITFEGLLIRSIIT
>LA_scaffold968_8.mRNA1
MSLCVVTADHKMLSTKKTEYRGQRIMAVDVSKLNREWEAKAMEVWGQPKSKVTHLVFYTTSYRDMPGPEYYLTKLLGGTHSIHHYQYHGGFQEATVLIHFRDFANKSHINGPALVVCSAFMAQDLQRSSEKLEVTRHLSSTTNTTFHSKMVERRRSLGTIIGSSHRPVEGSSSRAITGSSHRPIVEGTSSRAIVEGSSSRAITESSHRAIVEGSLSRAITRSSHRPIVEGSSSRAIVEGSSSRAITANHAQSQRTSRLQQSIADAMGVNASDVKIKVNVNINVQADITGAQIRRERIRFG
>LA_scaffold1112_3.mRNA1
MVMGDVPSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMYLTEEFLKDNANMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWVAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
>LA_scaffold1175_18.mRNA1
MGSIDAVELGSEKKPNAGKATILAIGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILNKYPELAIEGGSTVTQRLDICNDAVTEMAVEASRVCIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKELGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPRADRPYDLVGVALFGDGAGAIIIGSDPDPICEKPLFELHTAIQNFLPDTEKIIDGKLTEEGINFKLSRELPQIIEDNVENFCKKLITKAGLVHKDYNQMFWAVHPGGPAILNRIEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESKKVKNMNEGENEWGLILAFGPGVTFEGIVARNLDV
>LA_scaffold1500_3.mRNA1
MLTLGKAFPFPSTVVSQENLVEEYLREIKCDYLSIKTSCSTCIAIEGSPTIKQRLEIANDAVLLMAYEASLVCIKEWGRAVEDITNIVYVSSSEFCLPGGDLYLSAQLGLRNEVQRVMMYFLGCYGGVTRLHVAKDIAENNRGSWVLLITSETTVMGFCPPNKAHPYDLVGAALFGDGAAALIIGTDPTESEPPFMKLHYTLQQFLPGTQGVIDGRLSEEGISFQARKIPPSEGRRQRR
>LA_scaffold1846_40.mRNA1
MVMGDTPSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKDNANMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>LA_scaffold3159_5.mRNA1
MVMGDTPSLDEIRKAQRSDGPAGILAIGTANPENHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKDNANMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSNITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSNPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSGKDGEATTGEGLEWGVLFGFGPGLTVETVVLHSVPL
>LA_scaffold3385_1.mRNA1
MLASTRVEKQKDISTSPRRVANKGKATLLALGKAFPSNVVSQENLVEEYLREIKCDDLSIKDKLQHLCKTTTVKTRYTVMSRETMQKYPELASEGSPTIRQKLEIANDAVVKMAYEASLVCIKEWGRTVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGLTGLRVAKDIAENNLGSRVLLITSETTVLGFRPPNKARPYDLVGAALFGDGAAALIIGANPTELESPFMELHYALQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLMAKATSGSDSLKLNDIFWAVHPGGPAILNGLESKLKLKPEKLECSRQALVDYGNVSSNTIFYIMDKVRDELEKKGSEGEEWGLGLAFGPGITFEGFLIRSL
>LA_C70055_2.mRNA1
MGSIDATELCSKKKPNVGKATILAFGKAFPHQLVMQEYLVDGYLKTTKCDDPELKQKLTRLCNVLLLTFDLSFCKTTTVKTRYVVMSEEILRKYPELAVEGGSTVTQRLDICNDAVTEMAVEASKACIKNWGRSLSDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSMDRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTEEGIHFKLSRELPQIIEDNVENFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRIEKRLNLSPEKLSSSRRALMDYGNASSNSIIYVLEYMLEESKKARNMKEQENEWGLILAFGPGVTFEGIVARNLDA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University