Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Laqenaria siceraria
Species name
White-flowered gourd (Lagenaria siceraria) is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Laqenaria_siceraria.HIDH.fa
Download
>Lsi04G021350.1
MALIGEAPGYFEVYSDGSVRRLIPEVVVSTDTQSSKNYKFKDVIIDSKKLVTGRLFLPNVTNSATKLPILVYFHGGGFCIGSTTWIGYHNFLGDLAITSESVILSIDYRLAPENRLPAAYEDCYNSLEWLSYQASYEPWLQNVDLSRVFLSGDSAGGNIVHHVAVKTIKSNISNLTIKGLLLIHPYFGSEKRTENEKVQGAKGFVEMNDMFWRLSIPSGRDRDYFGCNYENNAQQVTKEEWGRFPNVVVFVAGLDFLKERGELYAKFLQKMRVKEVKLIEAEDESHVYHVFHPESEATRLLQKQMSQFMKRY
>Lsi04G015780.1
MAADSNSTELDLELLPYLRLYKNGVVERLLGTRVTPPGLDTRTGVESKDIIIVPETGVSARLYRPTAVDPPRKLPLVVYFHGGAFLVASSAEPIYHNNCLIPLVAEAQTVLLSVNYRLAPEHPLPAAYDDSWAALQWITAQSQSSADEPGHEPWLKELVFLVGDSAGGNISHHMALQAKNSDLTTKIKIEGIALIQPYFWGQEPIGSEITEHHKKAEVDRWWNFVCPSDRGNDDPLINPFSDGSPAIDGLVGDKVVVIVAGKDILRDRGKLYYENLAKSEWKGKVEIYETEGENHAFHMLDPTSEKAKALTKRLAFFLNEIKHSKLFCFSCETDGL
>Lsi04G002750.1
MRTKRMPTINLDQIPSFEEHGNGFNQHDVLVEEIDGLIRVYGNGYVERPQIVPCVSNALPPELGVTSWDVVVDKLTNIWARFYIPTQCQEKLPLIVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKTLQWLKQVAFVGAKQNWWSRYCDFTKIYLSGDSAGGNIAFNVAAGLGGKTTASGAVVLKPLVVKGNILIQPFFGGESRTKSEKFLVQPPRSPLTLAVSDTYWRLALPSGTNRDHPWCNPSAKGLFKVEDLRVLPSLICISELDILKDRNLEFCSALHRAGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLCA
>Lsi06G005890.1
MGNDDLLINPFSDGSLAIDGIAGDKVVVIVAGKDIPRDRGKLYYENLAKSDGKERWRFMRRKVRIMHFIC
>Lsi07G009850.1
MTREGGRWSVGLVSTGRKKGDEASSHHSHLIYYMKFKRMAALSIDPRLKLQMPKLRIQNEATAEEIEGLIRVYADGRVERPPIIPNVSCSTTASDKGVTAKDVLIDNFTNTWARIYVANSQRNLPLLVYFHGGGFCVGSAAWSCYHEFLLDLASKAKCVILSVNYRLSPEHRLPAAYEDGFNTIMWLKKHAITNPIEHKWWLGNCNPSKLFLAGDSAGANIAYNIVARLGLNEPTILKPLTLKGIILIQPFFGGESRTKSEKLAAQPSSASALTLDAADTYWRLSLPPGANRDHSWSNPLMNGGAKLRETKVPPLMVCISELDILVDRNLEFCAAMAAAGKQVERVILKGVGHSFQILNKDQISCVRRREMMGCIQAFIQQ
>Lsi08G009270.1
MTKGKSLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHDDFIDGVAVRDLVIDQNSGLRVRIYLPEVKCSGGKKLPVVIHFHGGGFCISEADWYMYYHTYTNLVRSAEAICVSVYLRRAPEHRLPVAIDDGFSALKWLQSVALGNETEPWIVENADFNRVFLIGDSSGGNLVHSVAALAGEIDLTPLKLAGGIPIHPGFVRAKRSKSEIENPQSPFLTLDMVDKFLSLSLPVGSTKDHPITCPMGIDALPLEKLNLPPFLLCIAEKDLIIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIAMKMDPETAAESDRLFAGIARFIKQH
>Lsi10G002940.1
MASSPNKNDDVTYDFFPFVRIYKDGRGQRLQITSDIVSANANDPKSAFRSKDVMISADPSVSACIFIPSSADPNQKLPILLYIHGGGFCIESTFNLQYHNYVGSLAVKANVVAVSIEYRLAPEHLFPAC
>Lsi10G002910.1
MASTEIAHNFSPMLIVYKDGRAHRLAGNELIDPSLDPITGVESKDVVISPETAVSARIYRPKPTAQPQKLPLLVYIHGGGFCIESAFSPTYHRHLNSLVAKANIVAVSVDYRLAPEHPLPIAYEDSWAALKWVAGHSAGTGPEEWLNEIADLDRVYFAGDSAGGNIANRLAIRVGTEGLAGLNLRGLILVHPYFWGGKLIGDEEKLNPEARSFIEKLWYLVCPTISGLDDPIVNPEFEPKLGQLAAERVAVYVAEKDALKDRGWFYSECLKKSGWGGAVEVVETKGQGHVFHLFNPTSDEALDFVGKLAACINGGRRE
>Lsi10G003030.1
METDAAAGDGVVHEFPPAFCVLKSGRIQRLFSDERLPPSTDPLTGVQSKDILIDPLTQLFVRIYLPNVSDSTKKLPLLIYIHGGAFSIGSVTAPMYHYHLISLAAEANAIALSVEYRLAPEHPLPAAYEDSWAAVEWAASHSNHDGAEIWLNQHADFNRVFFVGDSAGGNICYNMVGRASESDNGLKGMKIVGLGLVHPFFMIDQPDKLIEYIFPTTVCLEDPRLNPWVNPRLGKLRCERVLIMAAELDDLKDRAHGFHAALRESGFEGSVEIVETEGEIHVFHLFYPEKEKAAALVKKVASFIQSV
>Lsi10G002980.1
MDSQQEEIIFEFLPVFRVFKNGRVDRLLLTDRVPPSTDQLTGVQSKDFLIDPQTGVSVRLYLPKLSDSTIKLPLLIYIHGGAFSVGSPASPMFHNHLISLTAQANAVALSVDYRLAPENNLPAAYDDAWTAVEWAASHSNRNGPEIWLNEHADLNRVFVVGESAGANISYNVMGRASENENGLN
>Lsi10G002950.1
MDSQQEEIVFEFLPVFRVFKTGRIDRLILTDRVPPSTDQLTGVQSKDFLIDPQTGVSVRIYLPQLSDSTNKLPLLIYIHGGAFVVGSPACLMFHNHLISLAAQANAVALSVEYRLAPENNLPAAYDDAWTAVEWAASHSNHNGPEIWLNEHADFNRVFVVGESAGANISYNVMGRASENENGLNGMKVIGLGLVHPYFMIDKPDKLIEYVFPTSAGLEDPRINPKANPGLGKLRCNRVLIFSAENDSLKYGAIGVHAAFKESGFEGSVEMVETEGEGHGFHLFNPDTEKAHEVVKQLAFFIQSPLP
>Lsi10G002990.1
MLMTPRKSSYSDAFLVGSVASPNYHCHLVSFAAEANAIALSIEYHLALEHPLPTAYDDAWATVELETSHCNRNNTKIWPNEHGAWILHGVGESGWKGLVEMVETKGEVHAFYLFKPWCEKAIPLVKKVASFIQST
>Lsi10G003000.1
MLIDDRAFSVASAASPNYHRHLVSFAAEANIVAISVEYQLARENSLSTTYDDAWAVVEGAASHCNRDDAKIWLNEHTNFDHVFIVQG
>Lsi10G009590.1
MATTPFEVDECRGVLRVYSDGSIVRSSNPSFNVPVLDDGSVLWKDLLFDPIHHLHLRLYKPAAISSSKLPLFFYIHGGGFCIGSRTWPNCQNYCFRLAAELPALVISPDYRLAPENRLPAAIDDGFAALRWLQAQAESDHPDPWLADVADFSRVFISGDSAGGNIAHHLAAGLGLGSPELAPVRVRGYVLLAPFFGGTVRTRSEAEGPKEAFLNLELIDRFWRLSIPIGSSTDHPLVNVFGPRSRNLEAVEMDPIMVVVGGADLLKDRAVEYAEKLKKQGKKIELVDFEGKQHGFFTIDPNSEASNQLMLLINHFIAQHSL
>Lsi10G002920.1
MASSPNKNDDVAYDFFPFVRIYKDGRVQRLQITSYIVSADADDPKSAFLSKDVTISADPAVSARIFIPSFADPNQKLPILLYVHGGGFCIESAFNLQYHSYVGSLAVKANVVAVSVEYRLAPEHLFPACYEDCWDALRWVATHVNRDGPEPWLNNHADFNRVCLAGDSAGANICNHLAVRAGSSAEQLGGIKVVAMALIHPFFGDGGDDRLWKYLCSDQTRSARPRTEDLAKLPCGRVKVFLAEEDFLKVGGRNYGEDLKRSRWNGAVETVEHDGEDHVFHLKKPECEKALDLLEKLASFINLD
>Lsi10G002930.1
MASSPNKNDDVAYDFFPFVRIYKDGRIQRLQITFDIVSANADNPKICFPIKRCHDLGGSRCVGAYFIPSSTDLNQKLPILLYVHSGGFCIESTFNLQYHNYVGSLAVKANVVAVSVEYRLALEHLLPACYDDCWDALWWVTAHVNR
>Lsi10G002900.1
MKKKSEGIVFFVCCFFLLLSDSAMASDEIALNAAPYFIFYKDGRIDRLIGNDIDPPGLDHKTGVESKDVDISPEVTVRMYRPKSAAGKQAQKLPLLVYFHGGGFCIETAFSPFYHQHINALVAEGNIAAISVNYRRAPEYQLPIPFEDSWAAMKWIAAHSGGKGPDEWLNEIADLNQVYLAGDSAGGNIAHRMALRVATEGLDGVKIKGLQLIHPHFWGEKLIGEEKQWDPKDLHVVENLWYLVSKDIKKLDHPIVNPEHDPDLGRLAAERVAVYVAEKDNLKERGRHYAECLKKSGWSGTVEVVETDGEGHVFHLFNPTCDMAAELVKQLAAFINSGRRG
>Lsi10G003020.1
MDSDAAGGDGVVFEFLPVFRVFKSGRVQRLFPCDRLPPSTDQLTGVQSKDIFIDPLTQLSVRIYLPHLSHSTKKLPLLIYIHGGAFSIGSVASPIYHHHLISLAAESNAVALSVEYRLAPENPLPAAYDDAWAAVEWAASHSNRDGVEIWLNQHADFDRVFVVGDSAGANIAYNVVGRASESSNGPKGMKIIGLGLVHPFFMIDKPDKLMEYIFPTSAGLEDPRLNPWANPGLGKLRCERVLIMAAELDGLKDRARGFHAALRESGFEGSVEIVETEGEDHAFHLFNPETDKAVALVKKVASFIQSK
MALIGEAPGYFEVYSDGSVRRLIPEVVVSTDTQSSKNYKFKDVIIDSKKLVTGRLFLPNVTNSATKLPILVYFHGGGFCIGSTTWIGYHNFLGDLAITSESVILSIDYRLAPENRLPAAYEDCYNSLEWLSYQASYEPWLQNVDLSRVFLSGDSAGGNIVHHVAVKTIKSNISNLTIKGLLLIHPYFGSEKRTENEKVQGAKGFVEMNDMFWRLSIPSGRDRDYFGCNYENNAQQVTKEEWGRFPNVVVFVAGLDFLKERGELYAKFLQKMRVKEVKLIEAEDESHVYHVFHPESEATRLLQKQMSQFMKRY
>Lsi04G015780.1
MAADSNSTELDLELLPYLRLYKNGVVERLLGTRVTPPGLDTRTGVESKDIIIVPETGVSARLYRPTAVDPPRKLPLVVYFHGGAFLVASSAEPIYHNNCLIPLVAEAQTVLLSVNYRLAPEHPLPAAYDDSWAALQWITAQSQSSADEPGHEPWLKELVFLVGDSAGGNISHHMALQAKNSDLTTKIKIEGIALIQPYFWGQEPIGSEITEHHKKAEVDRWWNFVCPSDRGNDDPLINPFSDGSPAIDGLVGDKVVVIVAGKDILRDRGKLYYENLAKSEWKGKVEIYETEGENHAFHMLDPTSEKAKALTKRLAFFLNEIKHSKLFCFSCETDGL
>Lsi04G002750.1
MRTKRMPTINLDQIPSFEEHGNGFNQHDVLVEEIDGLIRVYGNGYVERPQIVPCVSNALPPELGVTSWDVVVDKLTNIWARFYIPTQCQEKLPLIVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKTLQWLKQVAFVGAKQNWWSRYCDFTKIYLSGDSAGGNIAFNVAAGLGGKTTASGAVVLKPLVVKGNILIQPFFGGESRTKSEKFLVQPPRSPLTLAVSDTYWRLALPSGTNRDHPWCNPSAKGLFKVEDLRVLPSLICISELDILKDRNLEFCSALHRAGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLCA
>Lsi06G005890.1
MGNDDLLINPFSDGSLAIDGIAGDKVVVIVAGKDIPRDRGKLYYENLAKSDGKERWRFMRRKVRIMHFIC
>Lsi07G009850.1
MTREGGRWSVGLVSTGRKKGDEASSHHSHLIYYMKFKRMAALSIDPRLKLQMPKLRIQNEATAEEIEGLIRVYADGRVERPPIIPNVSCSTTASDKGVTAKDVLIDNFTNTWARIYVANSQRNLPLLVYFHGGGFCVGSAAWSCYHEFLLDLASKAKCVILSVNYRLSPEHRLPAAYEDGFNTIMWLKKHAITNPIEHKWWLGNCNPSKLFLAGDSAGANIAYNIVARLGLNEPTILKPLTLKGIILIQPFFGGESRTKSEKLAAQPSSASALTLDAADTYWRLSLPPGANRDHSWSNPLMNGGAKLRETKVPPLMVCISELDILVDRNLEFCAAMAAAGKQVERVILKGVGHSFQILNKDQISCVRRREMMGCIQAFIQQ
>Lsi08G009270.1
MTKGKSLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHDDFIDGVAVRDLVIDQNSGLRVRIYLPEVKCSGGKKLPVVIHFHGGGFCISEADWYMYYHTYTNLVRSAEAICVSVYLRRAPEHRLPVAIDDGFSALKWLQSVALGNETEPWIVENADFNRVFLIGDSSGGNLVHSVAALAGEIDLTPLKLAGGIPIHPGFVRAKRSKSEIENPQSPFLTLDMVDKFLSLSLPVGSTKDHPITCPMGIDALPLEKLNLPPFLLCIAEKDLIIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIAMKMDPETAAESDRLFAGIARFIKQH
>Lsi10G002940.1
MASSPNKNDDVTYDFFPFVRIYKDGRGQRLQITSDIVSANANDPKSAFRSKDVMISADPSVSACIFIPSSADPNQKLPILLYIHGGGFCIESTFNLQYHNYVGSLAVKANVVAVSIEYRLAPEHLFPAC
>Lsi10G002910.1
MASTEIAHNFSPMLIVYKDGRAHRLAGNELIDPSLDPITGVESKDVVISPETAVSARIYRPKPTAQPQKLPLLVYIHGGGFCIESAFSPTYHRHLNSLVAKANIVAVSVDYRLAPEHPLPIAYEDSWAALKWVAGHSAGTGPEEWLNEIADLDRVYFAGDSAGGNIANRLAIRVGTEGLAGLNLRGLILVHPYFWGGKLIGDEEKLNPEARSFIEKLWYLVCPTISGLDDPIVNPEFEPKLGQLAAERVAVYVAEKDALKDRGWFYSECLKKSGWGGAVEVVETKGQGHVFHLFNPTSDEALDFVGKLAACINGGRRE
>Lsi10G003030.1
METDAAAGDGVVHEFPPAFCVLKSGRIQRLFSDERLPPSTDPLTGVQSKDILIDPLTQLFVRIYLPNVSDSTKKLPLLIYIHGGAFSIGSVTAPMYHYHLISLAAEANAIALSVEYRLAPEHPLPAAYEDSWAAVEWAASHSNHDGAEIWLNQHADFNRVFFVGDSAGGNICYNMVGRASESDNGLKGMKIVGLGLVHPFFMIDQPDKLIEYIFPTTVCLEDPRLNPWVNPRLGKLRCERVLIMAAELDDLKDRAHGFHAALRESGFEGSVEIVETEGEIHVFHLFYPEKEKAAALVKKVASFIQSV
>Lsi10G002980.1
MDSQQEEIIFEFLPVFRVFKNGRVDRLLLTDRVPPSTDQLTGVQSKDFLIDPQTGVSVRLYLPKLSDSTIKLPLLIYIHGGAFSVGSPASPMFHNHLISLTAQANAVALSVDYRLAPENNLPAAYDDAWTAVEWAASHSNRNGPEIWLNEHADLNRVFVVGESAGANISYNVMGRASENENGLN
>Lsi10G002950.1
MDSQQEEIVFEFLPVFRVFKTGRIDRLILTDRVPPSTDQLTGVQSKDFLIDPQTGVSVRIYLPQLSDSTNKLPLLIYIHGGAFVVGSPACLMFHNHLISLAAQANAVALSVEYRLAPENNLPAAYDDAWTAVEWAASHSNHNGPEIWLNEHADFNRVFVVGESAGANISYNVMGRASENENGLNGMKVIGLGLVHPYFMIDKPDKLIEYVFPTSAGLEDPRINPKANPGLGKLRCNRVLIFSAENDSLKYGAIGVHAAFKESGFEGSVEMVETEGEGHGFHLFNPDTEKAHEVVKQLAFFIQSPLP
>Lsi10G002990.1
MLMTPRKSSYSDAFLVGSVASPNYHCHLVSFAAEANAIALSIEYHLALEHPLPTAYDDAWATVELETSHCNRNNTKIWPNEHGAWILHGVGESGWKGLVEMVETKGEVHAFYLFKPWCEKAIPLVKKVASFIQST
>Lsi10G003000.1
MLIDDRAFSVASAASPNYHRHLVSFAAEANIVAISVEYQLARENSLSTTYDDAWAVVEGAASHCNRDDAKIWLNEHTNFDHVFIVQG
>Lsi10G009590.1
MATTPFEVDECRGVLRVYSDGSIVRSSNPSFNVPVLDDGSVLWKDLLFDPIHHLHLRLYKPAAISSSKLPLFFYIHGGGFCIGSRTWPNCQNYCFRLAAELPALVISPDYRLAPENRLPAAIDDGFAALRWLQAQAESDHPDPWLADVADFSRVFISGDSAGGNIAHHLAAGLGLGSPELAPVRVRGYVLLAPFFGGTVRTRSEAEGPKEAFLNLELIDRFWRLSIPIGSSTDHPLVNVFGPRSRNLEAVEMDPIMVVVGGADLLKDRAVEYAEKLKKQGKKIELVDFEGKQHGFFTIDPNSEASNQLMLLINHFIAQHSL
>Lsi10G002920.1
MASSPNKNDDVAYDFFPFVRIYKDGRVQRLQITSYIVSADADDPKSAFLSKDVTISADPAVSARIFIPSFADPNQKLPILLYVHGGGFCIESAFNLQYHSYVGSLAVKANVVAVSVEYRLAPEHLFPACYEDCWDALRWVATHVNRDGPEPWLNNHADFNRVCLAGDSAGANICNHLAVRAGSSAEQLGGIKVVAMALIHPFFGDGGDDRLWKYLCSDQTRSARPRTEDLAKLPCGRVKVFLAEEDFLKVGGRNYGEDLKRSRWNGAVETVEHDGEDHVFHLKKPECEKALDLLEKLASFINLD
>Lsi10G002930.1
MASSPNKNDDVAYDFFPFVRIYKDGRIQRLQITFDIVSANADNPKICFPIKRCHDLGGSRCVGAYFIPSSTDLNQKLPILLYVHSGGFCIESTFNLQYHNYVGSLAVKANVVAVSVEYRLALEHLLPACYDDCWDALWWVTAHVNR
>Lsi10G002900.1
MKKKSEGIVFFVCCFFLLLSDSAMASDEIALNAAPYFIFYKDGRIDRLIGNDIDPPGLDHKTGVESKDVDISPEVTVRMYRPKSAAGKQAQKLPLLVYFHGGGFCIETAFSPFYHQHINALVAEGNIAAISVNYRRAPEYQLPIPFEDSWAAMKWIAAHSGGKGPDEWLNEIADLNQVYLAGDSAGGNIAHRMALRVATEGLDGVKIKGLQLIHPHFWGEKLIGEEKQWDPKDLHVVENLWYLVSKDIKKLDHPIVNPEHDPDLGRLAAERVAVYVAEKDNLKERGRHYAECLKKSGWSGTVEVVETDGEGHVFHLFNPTCDMAAELVKQLAAFINSGRRG
>Lsi10G003020.1
MDSDAAGGDGVVFEFLPVFRVFKSGRVQRLFPCDRLPPSTDQLTGVQSKDIFIDPLTQLSVRIYLPHLSHSTKKLPLLIYIHGGAFSIGSVASPIYHHHLISLAAESNAVALSVEYRLAPENPLPAAYDDAWAAVEWAASHSNRDGVEIWLNQHADFDRVFVVGDSAGANIAYNVVGRASESSNGPKGMKIIGLGLVHPFFMIDKPDKLMEYIFPTSAGLEDPRLNPWANPGLGKLRCERVLIMAAELDGLKDRARGFHAALRESGFEGSVEIVETEGEDHAFHLFNPETDKAVALVKKVASFIQSK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University