Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Lanxangia tsao-ko
Species name
Cao guo (Lanxangia tsao-ko) is a species of monocot in the family Zingiberaceae (ginger family).
Species info
Gene sequence info
Lanxangia_tsao-ko.COMT.fa
Download
>Atsa14G000137.t1
MAPPQLSPEEEEQACCRAHQLSSAAVLPMVLRTAIELGLLEMLVEAGPTAALSSEELAARLPTTNPSAADMVERILRLLAANAVVGCADDGGGRKYSAAPICKYFVQNDDGGTLADIVLLHQDQVMIDTWRYLTSSILNGGHPVMAAYGMTTFEYQGGDPRFNKLFNGAMKGHSTLVMNNMLSRYDGFADVQVLVDVGGNTGSNLRLITSFYPHIRGINFDLPHVVADAPALARVEHRGGDMFEAVPAGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGGKVVVVEYVLPSAPEATPEAMAIFQLDLCMAAYNVGGKERTAEELKALAKEAGFHGFNSLPVFAGTWVLEFIK*
>Atsa14G000139.t1
MAPPQMSPEEEEEEQTCFRAQQLSSAAVLPMVLRTAIELGLLEMLVEAGPTAALSSEELAARLPTTNPSAAGTVERILRLLAANYVVGCAADGGRWKYSAAPICKYLVQNDDGGTVANLVLLHLDQVMIDTWRYLTSSILNGGHPVMAAYGMTTFEYQGGDPRFNKLFNGAMKGHSTLVMNNMLNRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPVLARVEHRGGDMFEAVPAGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGGKVVVVEYVLPAAPEATPEAMAIFQLDLCMAAYSVGGKERTAEEFKALAKEAGFHGFNALPAFAGTWVLEFIK*
>Atsa15G000651.t1
MAASTGAGDHASSEMAKEARLAMMDLANMISVPMALNAVVRLNVPDAVWQSGLNAPLSAAEIIALLRPPPPPSSDPAILQRLLRLLASYGVFAETRCAASGTRRYALTAVGRTLVPSSSGGESYAAYVLQHHQDALVRAWPRIHEAVLDPTGPEPFARANHGVPAYAYYGGDREANALMQRAMQGVSEPFMETLLDGYGAASFGGDVQTLVDVGGSSGSCLHMIMQRFPNIKQGINFDLPEVVNAAPPLPGVKHVGGDMFQSVPAGDVIFMKWVLTTWTDEECTSILRNCYKVLPEGGGGKVIACEPVLPEETDDSRRTRALLEGDIFVMTIYRTQGRERTEEEFRRLGVAAGFSSCSAVYLDPFYTILEYTK*
>Atsa25G000447.t1
MFASVPNGDAIFMKWILHDWSDEHCAKILDNCWKALPEKGKVMLFECIVPVVPEVNLRAQGVLHMDLVMMAHNPGGKERTKEEFEALATQAGFQGFKSTYIYANTYIIEFTK*
>Atsa25G000448.t1
MSSVGAAEWELTQEEDEAACMYAMQLASASIPPMTLKAAIELGILEILANAGSAAKLSAAEIAAQLPTQNPQAAAMVDRMLRLLAAYDIVTCAVAGANADGDGRPARTYGPAPVCKYLAKNADGVSMAALALMNQDKVLMESWYHLKDAVLDGGIPFNRAYGMTAFEYHGTDPRFNTVFNEGMKNHSIILTKKLLEIYRGFDDVNVLVDVGGGIGATLYMITSKHPNIRGINFDLSHVISEAPPFPGVEHVGGDMFAAVPTADAIFLKWILHDWSDEHCAKLLKNCCSSLPAHGKVIVVECVLPVVPEPTLKAQGVFHLDLIMLAHNPGGKERTEQEFESLAKQAGFVGFKATYIFANAWVMEFTKEEAPEMTPEEDEVACMLAMTLGSASIPPMTLRAAVELGLLEILVKAGYGAKLSPAEIVAQLPTQNPQAAAMVDRILRLLSAYDVVACAVETGADGRVGRKYGAAPACKYLTKNEEGVSMAALVLMNQDKVLMESWYHLAEAVLDGGIPFNKAYGMTAFEYHGTDPRFNTLFNEGMKNHSIILTKKLLENYRGFEDIQVLVDVGGGVGGTLSMITAKYPRIKGINFDLPHVISEAPAFPGQNQ*
>Atsa26G000152.t1
MGSNVADEWQLTPEEDEAACMYAMQLASASIPPMTLKAAIELGLLEILAKAGPAAKLSSADVAAQLPTHNPHAPVMVDRILRLLAAYGIVTCAVTSPGIDGSPARTYGAAPVCKYLTENEDGVSMAALALMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNAVFNEGMKNHSIILTKKLLDVYRGFDNVNVLVDVGGGIGATLYMITSKHPNIKGINFDLPHVISEAPPFPGVEHVGGDMFAAVPSADAIFMKWILHDWSDEHCAKLLKNCYGALPASGKVIVVECVLPVVPEPTPKAQGVFHVDLIMLAHNPGGKERTEQEFESLAKKAGFAGFKATYIFANAWVMEFTK*
>Atsa03G000022.t1
MARDMIDEEDEACALALQICSSNILSFSIKTAIELRLFDVIVAARNAALSPAEIVACLPTAADNRQAAGMVDRLLRLLAAHGIVTCVTDATSRARKYAAAPVSKYLIIKGKADGTGAASSSSMAGLALLFQDKSHHIAWEHMKDLVLHGGEAVKRAALSFDYLGGDSQIGKAFHNAMGGYSSVILKQLLPVYHGFDDVEVLVDVGGGNGTSLSLITAAHPHVKGINFDIQPVISQVPPIPGVKHVSGDMFESIPTADAIFMKWILHDWGDEECVKILKNCWKALLENGKVMVVECLLPAIPEQTAKARSVLQSDVGMMVCFLGGKERSEEEFKALASEAGFRGFKIAQEFAGTWVVMELTK*
>Atsa06G001203.t1
MDEEAACARSLQICGSCIFPFTVKTVIELRLLDVIAEAESPATALYPKQIVAQLPAAADNPEAADMVDRLLRLLASYGVVTCTSEGGSRKYSAAPVTKYLIKNADDGASSMVNLALLNQDRVMVAVWDQMKDSVLHGGLPLQNVFGMSTFEQLGSDARLNKVFNDAMGGCSFVFMKQLLRVYRGFDDVDVLVDVGGNAGASLRMITSEHPHLRGINFDVPHVISQAPPISGVQHVSGDMFEAVPSGDAIFMKWILHNWSDEQCVKILKNCWGALAQNGKVIVAECVLPELPEQTVKAQAVFQLDLIMMAYCLGGKERSEKEFKDLAMEAGFRGFKVTHRFAANWAVMEFTK*
>Atsa09G001511.t1
MDSNAAAFQLTPEEDDEACARARQLTTGAVLPMVLKTAIELGLLQMLVDAGPAAALGPDEIAARLTTQNPSAPDMVDRMLRLLAAHDIVRCAAAEGGRRKYSPAPICKYLTDNDAAAGSMASLVLMHHDEVMINIWRCLKEAILNGGHPVLAAYGMTTFEYQAGDPRFSKVFNNAMKGVSSLVVKHLLRKYNGFDDVRVLVDVGGNVGGNVHMITCFHPHIKGINFDLPHIIAGAPPLPGIEHRGGDMFESVPTGDAIFLKLILHDWSDELCVKLLKNCWKSLPEKGKVIVVESVVPAVPESSPTAKAVLQLDLSMMAYNVGGKERTEEEFRSLAAAADFRGFDLFPVFADSFVMEFIK*
MAPPQLSPEEEEQACCRAHQLSSAAVLPMVLRTAIELGLLEMLVEAGPTAALSSEELAARLPTTNPSAADMVERILRLLAANAVVGCADDGGGRKYSAAPICKYFVQNDDGGTLADIVLLHQDQVMIDTWRYLTSSILNGGHPVMAAYGMTTFEYQGGDPRFNKLFNGAMKGHSTLVMNNMLSRYDGFADVQVLVDVGGNTGSNLRLITSFYPHIRGINFDLPHVVADAPALARVEHRGGDMFEAVPAGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGGKVVVVEYVLPSAPEATPEAMAIFQLDLCMAAYNVGGKERTAEELKALAKEAGFHGFNSLPVFAGTWVLEFIK*
>Atsa14G000139.t1
MAPPQMSPEEEEEEQTCFRAQQLSSAAVLPMVLRTAIELGLLEMLVEAGPTAALSSEELAARLPTTNPSAAGTVERILRLLAANYVVGCAADGGRWKYSAAPICKYLVQNDDGGTVANLVLLHLDQVMIDTWRYLTSSILNGGHPVMAAYGMTTFEYQGGDPRFNKLFNGAMKGHSTLVMNNMLNRYDGFADVQVLVDVGGNTGSNLRLITSFYPHVRGINFDLPHVVADAPVLARVEHRGGDMFEAVPAGDAIMLKWILHDWSDEHCVKILKNCWKALPAEKGGKVVVVEYVLPAAPEATPEAMAIFQLDLCMAAYSVGGKERTAEEFKALAKEAGFHGFNALPAFAGTWVLEFIK*
>Atsa15G000651.t1
MAASTGAGDHASSEMAKEARLAMMDLANMISVPMALNAVVRLNVPDAVWQSGLNAPLSAAEIIALLRPPPPPSSDPAILQRLLRLLASYGVFAETRCAASGTRRYALTAVGRTLVPSSSGGESYAAYVLQHHQDALVRAWPRIHEAVLDPTGPEPFARANHGVPAYAYYGGDREANALMQRAMQGVSEPFMETLLDGYGAASFGGDVQTLVDVGGSSGSCLHMIMQRFPNIKQGINFDLPEVVNAAPPLPGVKHVGGDMFQSVPAGDVIFMKWVLTTWTDEECTSILRNCYKVLPEGGGGKVIACEPVLPEETDDSRRTRALLEGDIFVMTIYRTQGRERTEEEFRRLGVAAGFSSCSAVYLDPFYTILEYTK*
>Atsa25G000447.t1
MFASVPNGDAIFMKWILHDWSDEHCAKILDNCWKALPEKGKVMLFECIVPVVPEVNLRAQGVLHMDLVMMAHNPGGKERTKEEFEALATQAGFQGFKSTYIYANTYIIEFTK*
>Atsa25G000448.t1
MSSVGAAEWELTQEEDEAACMYAMQLASASIPPMTLKAAIELGILEILANAGSAAKLSAAEIAAQLPTQNPQAAAMVDRMLRLLAAYDIVTCAVAGANADGDGRPARTYGPAPVCKYLAKNADGVSMAALALMNQDKVLMESWYHLKDAVLDGGIPFNRAYGMTAFEYHGTDPRFNTVFNEGMKNHSIILTKKLLEIYRGFDDVNVLVDVGGGIGATLYMITSKHPNIRGINFDLSHVISEAPPFPGVEHVGGDMFAAVPTADAIFLKWILHDWSDEHCAKLLKNCCSSLPAHGKVIVVECVLPVVPEPTLKAQGVFHLDLIMLAHNPGGKERTEQEFESLAKQAGFVGFKATYIFANAWVMEFTKEEAPEMTPEEDEVACMLAMTLGSASIPPMTLRAAVELGLLEILVKAGYGAKLSPAEIVAQLPTQNPQAAAMVDRILRLLSAYDVVACAVETGADGRVGRKYGAAPACKYLTKNEEGVSMAALVLMNQDKVLMESWYHLAEAVLDGGIPFNKAYGMTAFEYHGTDPRFNTLFNEGMKNHSIILTKKLLENYRGFEDIQVLVDVGGGVGGTLSMITAKYPRIKGINFDLPHVISEAPAFPGQNQ*
>Atsa26G000152.t1
MGSNVADEWQLTPEEDEAACMYAMQLASASIPPMTLKAAIELGLLEILAKAGPAAKLSSADVAAQLPTHNPHAPVMVDRILRLLAAYGIVTCAVTSPGIDGSPARTYGAAPVCKYLTENEDGVSMAALALMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNAVFNEGMKNHSIILTKKLLDVYRGFDNVNVLVDVGGGIGATLYMITSKHPNIKGINFDLPHVISEAPPFPGVEHVGGDMFAAVPSADAIFMKWILHDWSDEHCAKLLKNCYGALPASGKVIVVECVLPVVPEPTPKAQGVFHVDLIMLAHNPGGKERTEQEFESLAKKAGFAGFKATYIFANAWVMEFTK*
>Atsa03G000022.t1
MARDMIDEEDEACALALQICSSNILSFSIKTAIELRLFDVIVAARNAALSPAEIVACLPTAADNRQAAGMVDRLLRLLAAHGIVTCVTDATSRARKYAAAPVSKYLIIKGKADGTGAASSSSMAGLALLFQDKSHHIAWEHMKDLVLHGGEAVKRAALSFDYLGGDSQIGKAFHNAMGGYSSVILKQLLPVYHGFDDVEVLVDVGGGNGTSLSLITAAHPHVKGINFDIQPVISQVPPIPGVKHVSGDMFESIPTADAIFMKWILHDWGDEECVKILKNCWKALLENGKVMVVECLLPAIPEQTAKARSVLQSDVGMMVCFLGGKERSEEEFKALASEAGFRGFKIAQEFAGTWVVMELTK*
>Atsa06G001203.t1
MDEEAACARSLQICGSCIFPFTVKTVIELRLLDVIAEAESPATALYPKQIVAQLPAAADNPEAADMVDRLLRLLASYGVVTCTSEGGSRKYSAAPVTKYLIKNADDGASSMVNLALLNQDRVMVAVWDQMKDSVLHGGLPLQNVFGMSTFEQLGSDARLNKVFNDAMGGCSFVFMKQLLRVYRGFDDVDVLVDVGGNAGASLRMITSEHPHLRGINFDVPHVISQAPPISGVQHVSGDMFEAVPSGDAIFMKWILHNWSDEQCVKILKNCWGALAQNGKVIVAECVLPELPEQTVKAQAVFQLDLIMMAYCLGGKERSEKEFKDLAMEAGFRGFKVTHRFAANWAVMEFTK*
>Atsa09G001511.t1
MDSNAAAFQLTPEEDDEACARARQLTTGAVLPMVLKTAIELGLLQMLVDAGPAAALGPDEIAARLTTQNPSAPDMVDRMLRLLAAHDIVRCAAAEGGRRKYSPAPICKYLTDNDAAAGSMASLVLMHHDEVMINIWRCLKEAILNGGHPVLAAYGMTTFEYQAGDPRFSKVFNNAMKGVSSLVVKHLLRKYNGFDDVRVLVDVGGNVGGNVHMITCFHPHIKGINFDLPHIIAGAPPLPGIEHRGGDMFESVPTGDAIFLKLILHDWSDELCVKLLKNCWKSLPEKGKVIVVESVVPAVPESSPTAKAVLQLDLSMMAYNVGGKERTEEEFRSLAAAADFRGFDLFPVFADSFVMEFIK*
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University