Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in flavonoid biosynthesis.
C4H
Enzyme
Cinnamate 4-hydroxylase
Enzyme name
EC:1.14.14.91
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Sysname
trans-cinnamate + [reduced NADPH---hemoprotein reductase] + O2 = 4-hydroxycinnamate + [oxidized NADPH---hemoprotein reductase] + H2O[RN:R02253]
Reaction
4-hydroxycinnamate [CPD:C00811];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Lanxangia tsao-ko
Species name
Cao guo (Lanxangia tsao-ko) is a species of monocot in the family Zingiberaceae (ginger family).
Species info
Gene sequence info
Lanxangia_tsao-ko.C4H.fa
Download
>Atsa10G000018.t1
MDAVTEYLRAAPPGGVLVRGRLQLMLYDIMYRMMFEAQFESVDDPLFQQATQFNSERSRVAQRFDYNYGDFIPILRPFLKGCLEKCRGLQSRRLAFFFNDNYVEKRRTE*
>Atsa10G000017.t1
MAISVAKFAFLAVTSAFLANSGQSLVAVSIPLLFVVPFVLLSSSSSSSGGGGKTPPGPVAWPIFGNWLQVGNDLNLVGMAEKYGGVFLLRLGLRNLQAVVSDPKLAAEALHTQGVEFGSRPRNLVWDIFTASGKDMVFTEYGDHWRKMRRAIDHAFLHQQGIAQYRGMWEE*
>Atsa12G001396.t1
MAISVARFVGLTLLAVASAYLVKSGQSPVVACIPLLFVLPFFFMYYGGGGGGKTPPGPVALPIFGNWLQVGNDLNHRNLVGMANKYGDVFLLRLGVRNLAVVSDPKLAAEVLHTQGVEFGSRPRNLVWDIFTDSGKDMVFTEYGDHWRKMRRIMTMPFFTNKVVGQYRGMWEEEMNAVVESLRAAPTEGVVVRRRLQLMLYNIMYRMMFDARFESAEDPLFQQATRFNSERSRLAQSFDYNYGDFIPILRPFLKGYLDKCRDLQSRRLAFFNDNYVEKRRKVMSARDGSSDRLRCAMDYILEAEMNGEISSDNVIYIVENINVAAIETTLWGMEWALAELVNHPSCQKRLRDELHRVLGGEPVTETSLARLPYLEAVVKETLRLHSPIPLLVPHMNLDAAKLGGYEIPKRTKVIVNAWWLGNNPEWWVRPKEFRPERFLEEEGEVEAVVGGGKVDFRFLPFGVGRRSCPGIILAMPLLGLIVGKLVKEFEMAPPPGTEKIDVTEKGGQFSLQIAKHATIVFRPVLAA*
>Atsa19G001110.t1
MDWVLMEKALLGMFVAVTLAIVVSKLCGKRFKLPPGPRPVPIFGNWLQVGDDLNHRVLAGMAKRFGDIFHLLMGVRNLVVVSSPELAREVLHVQGVEFGSHTRNVVLDIFTGKGQDMAFTVYGDHWRKMRRIMTVPFFTNKVVQQSREGWEEEIRLVVKELRSNPKAASEGVVLRRRLQLMMYNNMFRIMFDRRFESEEDPLFNKLKAINFERSRLSQSFEFNYGDFIPVLRPFLRGYLNKCREVKDRRLRIFHEHFVAERKKMMEEKESKFEVKCAMDHILDAERRGEINYDNVLYIVENINVAALETTLWSIEWGIAELVNHPAIQSKLRRELDAALGSSQLTEPDLVRLPYLNAVVKETLRLRMAIPLLVPHMNLHDAKLAGFNVPAESKILVNAWWLANNPALWKNPDQFRPERFLEEEAGLEANGNDFRFLPFGAGRRSCPGIVLALPIIGITLGCLVHNFELLPPPGKGKVDTAEKAGQFSLQIMTHSAVVCKPRKV*
>Atsa03G000698.t1
MDLLLLEKALLALFAAVTLAIVVSKLRGKHFKLPPGPLPVPVFGNWLQVGDDLNHRNLTTLAKRFGDIFLLRMGVRNLVVVSSPDLSREVLHAQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNRQGWEEEARLVVEDVKKDPKAATEGVVLRRRLQLMMYNNMYRIMFNFRFQGMDDPLFNKLKAANGERSRLAQSFEYNYGDFIPILRPFLRGYLKKCQELKDNRLKLFDDHFVSEKKKMMDKLGSKLELNCAMDHILDAERRGEINYDNVLYIVENINVAAIETTLWSIEWGVAELVNHPEIQRKLRAELDTVLGEGVPITEPDIQRLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPAYWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFYLLPPPGTDKVDTTEKGGQFSLHILKHSTIVCEPRA*
>Atsa06G001650.t1
MDLVFAEKALLGLFAAVTLAIVVSKLCGKRFKLPPGPRPVPIFGNWLQVGDDLNHRMLTGMAKRFGDIFHLLMGVRNLVVVSSPELAREVLHAQGVEFGSRTRNVVLDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNREGWEEEMRLVVEELRSNPKAATEGVVIRRRLQLMMYNNMFRIMFDRRFESEEDPLFNKLKVINFERSRLSQSFAFNYGDFIPVLRPFLRGYLNKCREVKDRRLRLFHEHFVAERKKMMEEKGSKFELKCAMDHILDAERRGEINYDNVLYIVENINVAALETTLWSIEWGIAELANHPAIQIKLRRELDAVLGSAQLTEPDLVRLPYLHAVVKETLRLRMAIPLLVPHMNLHDAKLAGFDVPAESKILVNAWWLANNPALWKDPEQFRPERFLEEEAAVEANGNDFRFLPFGVGRRSCPGIVLALPIIGIALGRLVHNFELLPPPGKDKVDTAEKAGQFSLQIMTHSTVVCKPTKL*
>Atsa09G000055.t1
MDLLLLEKGLLGLFAAVTLAIVVSKLRGKHFKLPPGPLPVPVFGNWLQVGDDLNHRNLTDLAKRFGDILLLRMGIRNLVVVSSPELAREVLHAQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNRQGWEEEARQVVEDVKKDAKAATQGVVLRRRLQLMMYNNMYRIMFNYRFQGMDDPLFNKLKAANGERSRLAQSFDYNYGDFIPILRPFLRGYLKKCQDLKDNRLSLFDDHFVAQKKKMMEEMGSKMELNCAIDHILDAERRGEINYDNVLYIVENINVAAIETTLWSIEWGVAELVNHPEIQRKLRAELDTVLGPGVPITEPDIQRLPNLQAVIKETLRLRMAIPLLVPHMNLHDAKLSGYDIPAESKILVNAWWLANNPAHWKKPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFELLPPPGTKQVDTTEKGGQFSLHILEHSTVVCKPRA*
MDAVTEYLRAAPPGGVLVRGRLQLMLYDIMYRMMFEAQFESVDDPLFQQATQFNSERSRVAQRFDYNYGDFIPILRPFLKGCLEKCRGLQSRRLAFFFNDNYVEKRRTE*
>Atsa10G000017.t1
MAISVAKFAFLAVTSAFLANSGQSLVAVSIPLLFVVPFVLLSSSSSSSGGGGKTPPGPVAWPIFGNWLQVGNDLNLVGMAEKYGGVFLLRLGLRNLQAVVSDPKLAAEALHTQGVEFGSRPRNLVWDIFTASGKDMVFTEYGDHWRKMRRAIDHAFLHQQGIAQYRGMWEE*
>Atsa12G001396.t1
MAISVARFVGLTLLAVASAYLVKSGQSPVVACIPLLFVLPFFFMYYGGGGGGKTPPGPVALPIFGNWLQVGNDLNHRNLVGMANKYGDVFLLRLGVRNLAVVSDPKLAAEVLHTQGVEFGSRPRNLVWDIFTDSGKDMVFTEYGDHWRKMRRIMTMPFFTNKVVGQYRGMWEEEMNAVVESLRAAPTEGVVVRRRLQLMLYNIMYRMMFDARFESAEDPLFQQATRFNSERSRLAQSFDYNYGDFIPILRPFLKGYLDKCRDLQSRRLAFFNDNYVEKRRKVMSARDGSSDRLRCAMDYILEAEMNGEISSDNVIYIVENINVAAIETTLWGMEWALAELVNHPSCQKRLRDELHRVLGGEPVTETSLARLPYLEAVVKETLRLHSPIPLLVPHMNLDAAKLGGYEIPKRTKVIVNAWWLGNNPEWWVRPKEFRPERFLEEEGEVEAVVGGGKVDFRFLPFGVGRRSCPGIILAMPLLGLIVGKLVKEFEMAPPPGTEKIDVTEKGGQFSLQIAKHATIVFRPVLAA*
>Atsa19G001110.t1
MDWVLMEKALLGMFVAVTLAIVVSKLCGKRFKLPPGPRPVPIFGNWLQVGDDLNHRVLAGMAKRFGDIFHLLMGVRNLVVVSSPELAREVLHVQGVEFGSHTRNVVLDIFTGKGQDMAFTVYGDHWRKMRRIMTVPFFTNKVVQQSREGWEEEIRLVVKELRSNPKAASEGVVLRRRLQLMMYNNMFRIMFDRRFESEEDPLFNKLKAINFERSRLSQSFEFNYGDFIPVLRPFLRGYLNKCREVKDRRLRIFHEHFVAERKKMMEEKESKFEVKCAMDHILDAERRGEINYDNVLYIVENINVAALETTLWSIEWGIAELVNHPAIQSKLRRELDAALGSSQLTEPDLVRLPYLNAVVKETLRLRMAIPLLVPHMNLHDAKLAGFNVPAESKILVNAWWLANNPALWKNPDQFRPERFLEEEAGLEANGNDFRFLPFGAGRRSCPGIVLALPIIGITLGCLVHNFELLPPPGKGKVDTAEKAGQFSLQIMTHSAVVCKPRKV*
>Atsa03G000698.t1
MDLLLLEKALLALFAAVTLAIVVSKLRGKHFKLPPGPLPVPVFGNWLQVGDDLNHRNLTTLAKRFGDIFLLRMGVRNLVVVSSPDLSREVLHAQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNRQGWEEEARLVVEDVKKDPKAATEGVVLRRRLQLMMYNNMYRIMFNFRFQGMDDPLFNKLKAANGERSRLAQSFEYNYGDFIPILRPFLRGYLKKCQELKDNRLKLFDDHFVSEKKKMMDKLGSKLELNCAMDHILDAERRGEINYDNVLYIVENINVAAIETTLWSIEWGVAELVNHPEIQRKLRAELDTVLGEGVPITEPDIQRLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPAYWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFYLLPPPGTDKVDTTEKGGQFSLHILKHSTIVCEPRA*
>Atsa06G001650.t1
MDLVFAEKALLGLFAAVTLAIVVSKLCGKRFKLPPGPRPVPIFGNWLQVGDDLNHRMLTGMAKRFGDIFHLLMGVRNLVVVSSPELAREVLHAQGVEFGSRTRNVVLDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNREGWEEEMRLVVEELRSNPKAATEGVVIRRRLQLMMYNNMFRIMFDRRFESEEDPLFNKLKVINFERSRLSQSFAFNYGDFIPVLRPFLRGYLNKCREVKDRRLRLFHEHFVAERKKMMEEKGSKFELKCAMDHILDAERRGEINYDNVLYIVENINVAALETTLWSIEWGIAELANHPAIQIKLRRELDAVLGSAQLTEPDLVRLPYLHAVVKETLRLRMAIPLLVPHMNLHDAKLAGFDVPAESKILVNAWWLANNPALWKDPEQFRPERFLEEEAAVEANGNDFRFLPFGVGRRSCPGIVLALPIIGIALGRLVHNFELLPPPGKDKVDTAEKAGQFSLQIMTHSTVVCKPTKL*
>Atsa09G000055.t1
MDLLLLEKGLLGLFAAVTLAIVVSKLRGKHFKLPPGPLPVPVFGNWLQVGDDLNHRNLTDLAKRFGDILLLRMGIRNLVVVSSPELAREVLHAQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNRQGWEEEARQVVEDVKKDAKAATQGVVLRRRLQLMMYNNMYRIMFNYRFQGMDDPLFNKLKAANGERSRLAQSFDYNYGDFIPILRPFLRGYLKKCQDLKDNRLSLFDDHFVAQKKKMMEEMGSKMELNCAIDHILDAERRGEINYDNVLYIVENINVAAIETTLWSIEWGVAELVNHPEIQRKLRAELDTVLGPGVPITEPDIQRLPNLQAVIKETLRLRMAIPLLVPHMNLHDAKLSGYDIPAESKILVNAWWLANNPAHWKKPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFELLPPPGTKQVDTTEKGGQFSLHILEHSTVVCKPRA*
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University