Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Amborella trichopoda
Species name
Amborella trichopoda is a species of flowering plant in the family Amborellaceae.
Species info
Gene sequence info
Amborella_trichopoda.HIDH.fa
Download
>XP_006826793.2
MRRRRMGLISLGDSKHQIGSIDRGHGSVIDEIPGLIRVYKDGHVYRYPVVQESPCTIETGVSSRDFSIDCGLWARFYVPNRVDKPALLIYFHGGGFCVGSAAWKCYHEFLSKLAVKSGCVIMSVNYRLAPEHPLPAAYDDGFVALTWAIRRVGAGSGADDPSRWLARCDSSRVFLAGDSAGANIAHHVMARHGSEPGSRLSLRGTILIQPFFGGEPRTDSEKHLVQPPDSALTLATSDTYWRLALPPDSSRDHFWCNPLSSKSPLKLEEVKLPAILVCVSENDILKDRDLGYCEGLRKMGKKVQVMVYGGVGHAFQVLHNSPMAGIRTLELISHVANFINS
>XP_006837038.2
MRPHFSVLSLAINPLHLGNVEAMKDGKVFTNTGRFIGGNKRGLMGIYKDRSADKVQLNIEEEIEEEIQGLMRVHKGGLVERLSPLFIEVPPDLDDPLVVSKDVGINQEKGTWARVYLPKHHARREKLPILVYFHGGGFCLGSAAWSIYHSFISHLAREIGCLVVSVSYRLAPECKIPSQYEDGIEALEWVSHQKDAWLVNHGNLRRIFIGGDSAGANIAHHVSLSARVALSGCLLMQPFFGGEDVLRWEEEIEDPALPHKWVDTFWKWALPEGATKDHPACNPLLESPKSWPEGLPILVLVAERDLMRERGVIYANAMTRAGKPVRLVVSEGVGHGFQVFQPNSDAIPKLLRHLGEFVKENSKGGRGHGPVSSLHFGARPANGIHVLRI
>XP_006849403.1
MAARDGDKTVVDELPGIVTIYYDGSIVRHNSHTTTPPTEFPTDATVASKDVVLNPVTGLWARLFLPHHQQNVPLAVYFHGGGFCFGDPAWDFYTRFISRLATATSTLWASVAYRLAPEHRLPVGFHDCLDAISSLTTSTDLWLKGTDCRHVFLAGDSAGGDLVYNCALHHCKEPHNRVEIVGLMLFHPGFIKEERSASETDSPKELVQVDATARMALPPGEDKNYFMLNPRVPPVAETRLPPCLVVVGGKDLFRDRQVEFCEKMEGMGQMVEVVWYEEMRHCFMFEEDTENSPEADDMVEKTVSFMERCGGFKKEG
>XP_011621287.1
MTVPPSSLSPAGVASRDVVILPETNLSARLYLPQSQVSSTRKLPTIIYFHGGGFIMESPFSSTYHPYTDALSAKSNALIVSVNYSRAPENPLPAAYEDGWSALKWVVQRWDPWLRDHANLDRIYLVGDSLGANLGHHMAMKAGIESLGVRVHGLVLVHPYFWASDVSEEEAKSSDMAEKLWKFSCPMTVGLDDPWINPMADGVGALKKLGCERVLVCLAEKDCLRQRGRVYYEALKKCRWEGVAEIVETEGEDHCFHLFDPESGRAKDFIDQLVSFITRC
>XP_011622365.1
MESSAVKEIEIDLSPYIRLYKDGTVDRLAGNEILPASLLSESGASSKDVTISRESGISARLYLPSSAGRGQKLPTLVYFHGGAFIIESPFSPLYHPYTESVSANSKALVVSIDYHRPPEHPLPAAYEDAWAALLWVVSRVDPWLGDYADLSRIFVGGDSAGANIAHHVALRAGTEGSEELKKLRGLILMHPYFWSSGLSEEERERGKTVGQMWKFACPDSEGVDDLWINPMAKGSEGLRNLGCEKVLICVAGKDFLKGRGVAYGEALRRSGWEGAVEVAEDEGEDHVFHLFNPERQKSKVMMERVSSFLED
>XP_011623550.1
MEAFKKYSPFVVHTDGTVERIKDTEILQPSPFSDAGVTSKDVDISPNVSVRLYIPHSALSSTTKLTTLVYFHGGGFVAESPFSPIFHTYQDALSAKAGAIIISVNYRLAPEHPLPAAYDDSWEAVEWTVGLSDEWLRDHADLDRLFLAGDSAGGNIVHQMGMRAGKPASKVRLRGLVLVHPFFWGPNLGDTEKEHKELVERMWKMASPPVVGIMQCHWVNWQAEDATPLSKLGCRQVMVCVAELDFLKKKGREYYEALKEIGWEGRVQFVETEGEGHGFHLIKPDCEKARVFMDQLVSFLNHV
>XP_011627913.1
METVDQTFEEYPPFLRIHNDGTIERLVGTQTVPPSPLSDAGISSKDVVISPNVSARLYIPHSALSSTKKLPTLVYFHGGGFIIESPFSPHYHPYQDSLAAKAGVIIVSVNYRLAPEHRLPTSYDDSWEAIKWTVGLSDEWLRDHADLDRLFFAGDSAGGNIVHQMAMRTSPSEIRLRGVVLVHPFFWGPNLSDTEKEQIGFVDMVWRLVSPDVGIMQSHWVNWEAERATPLTKLGCQRVMLCVAELDFLNKKGKEYYEALKESGWEGMVELVETEGEDHVFHLFKPDCEKARVFMEQVASFLNQG
>XP_011627914.1
METADQPFKEYPPFVRIHNDGTVERLMGTQTLPASPLSDVGVSSKDVVISPNVSARLYIPHSALSSTKKLPTLVYFHGGGFIIESPSSPHYHSYQDALAAKASVIIVSVNYRLAPEHQLPAAYDDSWEAIKWTVGLSDEWLRDHADLDRLFFAGDSVGGNIVHQMALRAGETASSEVRLRGAVLVHPFFWGPNLSDTEKEQNGFVDMFWRLVSPDVGAMQSHWVNWEAEGATPLTKLGCRRVMVCVAELDFIKKGKDYYEALKESGWEGKVEFVETEGEGHVFHLLNPDCEKARVFMEQVASFLNRV
>XP_011627915.2
METTDQPFKEYPPFVRIHNDGTVERHTGTQTLPPSPLSDAGVSSKDVVISPNVSARLYIPHSALSSTKKLPTLVYFHGGGFIIESPFSPHYHPYQDALAAKAGVIIVSVNYRLAPEHQLPAAYDDSWEAIKWTVGLSDEWLRDHADLDRLFLAGDSSGGNIVHQMAMRAGETASSEVRLRGVVLVHPFFWGPNLSDTENEQSGFVEKLWKLFSPDVGAMQSHWVNWEAEGATPLTKLGCRRVMVCVAELDFIKKKGKEYYEALKESGWEGKVELVETEGENHVFHLFKPDCEKARVFMEQVVSFLNQV
>XP_011627929.1
MASPANPKGILHEFPPFIRIYKDGTVELLIAANGEKLTTLLYFQGGAFVIESAFSPFYHRYLDALSAKANALIISVDYCLAPDHPLSTAYDDAWAAFQWIMDLSDPWLRDHADLDHLFLARDSAGANIAHRTTMRAGKSTGARVRRLVTIHPFFWGTDLKETARERSESVEKMSRFVCPKTNGLDDPQVNPGAEALERLGCRNMLVCVAGKDMSRERGRAYYEDVRRSGWEGVAEVMEIEEEDHIFHLFRPDCDNASLMMEQILMFLNND
>XP_011629233.1
MEAPKEILKNLPPFIRIYKDGTVERPLGTHTIPPSTLSAVGISSKDVVISPQVSARLYIPHSSLSSSPITKLATIVYFHGGAFVIGSPFSPFYNGYIETLSAKANALIVSVSYRLAPEHPLPTAYNDSWAAIEWTVSLSDEWLNDHADLNRIFLAGDSAGANITHQMAMRAGTKGSPIGLRGVVLVHPFFWGSDLSEEEEERSWSVNQMWTVACPTSDGIDDPWINPRAETAPPLKELGCQRVLVCLAGVDFLREKGKAYYEALRESGWEGVAEVVEVAEEGHAFHLFNQGCENAVKLMERIVDFISSGGTS
MRRRRMGLISLGDSKHQIGSIDRGHGSVIDEIPGLIRVYKDGHVYRYPVVQESPCTIETGVSSRDFSIDCGLWARFYVPNRVDKPALLIYFHGGGFCVGSAAWKCYHEFLSKLAVKSGCVIMSVNYRLAPEHPLPAAYDDGFVALTWAIRRVGAGSGADDPSRWLARCDSSRVFLAGDSAGANIAHHVMARHGSEPGSRLSLRGTILIQPFFGGEPRTDSEKHLVQPPDSALTLATSDTYWRLALPPDSSRDHFWCNPLSSKSPLKLEEVKLPAILVCVSENDILKDRDLGYCEGLRKMGKKVQVMVYGGVGHAFQVLHNSPMAGIRTLELISHVANFINS
>XP_006837038.2
MRPHFSVLSLAINPLHLGNVEAMKDGKVFTNTGRFIGGNKRGLMGIYKDRSADKVQLNIEEEIEEEIQGLMRVHKGGLVERLSPLFIEVPPDLDDPLVVSKDVGINQEKGTWARVYLPKHHARREKLPILVYFHGGGFCLGSAAWSIYHSFISHLAREIGCLVVSVSYRLAPECKIPSQYEDGIEALEWVSHQKDAWLVNHGNLRRIFIGGDSAGANIAHHVSLSARVALSGCLLMQPFFGGEDVLRWEEEIEDPALPHKWVDTFWKWALPEGATKDHPACNPLLESPKSWPEGLPILVLVAERDLMRERGVIYANAMTRAGKPVRLVVSEGVGHGFQVFQPNSDAIPKLLRHLGEFVKENSKGGRGHGPVSSLHFGARPANGIHVLRI
>XP_006849403.1
MAARDGDKTVVDELPGIVTIYYDGSIVRHNSHTTTPPTEFPTDATVASKDVVLNPVTGLWARLFLPHHQQNVPLAVYFHGGGFCFGDPAWDFYTRFISRLATATSTLWASVAYRLAPEHRLPVGFHDCLDAISSLTTSTDLWLKGTDCRHVFLAGDSAGGDLVYNCALHHCKEPHNRVEIVGLMLFHPGFIKEERSASETDSPKELVQVDATARMALPPGEDKNYFMLNPRVPPVAETRLPPCLVVVGGKDLFRDRQVEFCEKMEGMGQMVEVVWYEEMRHCFMFEEDTENSPEADDMVEKTVSFMERCGGFKKEG
>XP_011621287.1
MTVPPSSLSPAGVASRDVVILPETNLSARLYLPQSQVSSTRKLPTIIYFHGGGFIMESPFSSTYHPYTDALSAKSNALIVSVNYSRAPENPLPAAYEDGWSALKWVVQRWDPWLRDHANLDRIYLVGDSLGANLGHHMAMKAGIESLGVRVHGLVLVHPYFWASDVSEEEAKSSDMAEKLWKFSCPMTVGLDDPWINPMADGVGALKKLGCERVLVCLAEKDCLRQRGRVYYEALKKCRWEGVAEIVETEGEDHCFHLFDPESGRAKDFIDQLVSFITRC
>XP_011622365.1
MESSAVKEIEIDLSPYIRLYKDGTVDRLAGNEILPASLLSESGASSKDVTISRESGISARLYLPSSAGRGQKLPTLVYFHGGAFIIESPFSPLYHPYTESVSANSKALVVSIDYHRPPEHPLPAAYEDAWAALLWVVSRVDPWLGDYADLSRIFVGGDSAGANIAHHVALRAGTEGSEELKKLRGLILMHPYFWSSGLSEEERERGKTVGQMWKFACPDSEGVDDLWINPMAKGSEGLRNLGCEKVLICVAGKDFLKGRGVAYGEALRRSGWEGAVEVAEDEGEDHVFHLFNPERQKSKVMMERVSSFLED
>XP_011623550.1
MEAFKKYSPFVVHTDGTVERIKDTEILQPSPFSDAGVTSKDVDISPNVSVRLYIPHSALSSTTKLTTLVYFHGGGFVAESPFSPIFHTYQDALSAKAGAIIISVNYRLAPEHPLPAAYDDSWEAVEWTVGLSDEWLRDHADLDRLFLAGDSAGGNIVHQMGMRAGKPASKVRLRGLVLVHPFFWGPNLGDTEKEHKELVERMWKMASPPVVGIMQCHWVNWQAEDATPLSKLGCRQVMVCVAELDFLKKKGREYYEALKEIGWEGRVQFVETEGEGHGFHLIKPDCEKARVFMDQLVSFLNHV
>XP_011627913.1
METVDQTFEEYPPFLRIHNDGTIERLVGTQTVPPSPLSDAGISSKDVVISPNVSARLYIPHSALSSTKKLPTLVYFHGGGFIIESPFSPHYHPYQDSLAAKAGVIIVSVNYRLAPEHRLPTSYDDSWEAIKWTVGLSDEWLRDHADLDRLFFAGDSAGGNIVHQMAMRTSPSEIRLRGVVLVHPFFWGPNLSDTEKEQIGFVDMVWRLVSPDVGIMQSHWVNWEAERATPLTKLGCQRVMLCVAELDFLNKKGKEYYEALKESGWEGMVELVETEGEDHVFHLFKPDCEKARVFMEQVASFLNQG
>XP_011627914.1
METADQPFKEYPPFVRIHNDGTVERLMGTQTLPASPLSDVGVSSKDVVISPNVSARLYIPHSALSSTKKLPTLVYFHGGGFIIESPSSPHYHSYQDALAAKASVIIVSVNYRLAPEHQLPAAYDDSWEAIKWTVGLSDEWLRDHADLDRLFFAGDSVGGNIVHQMALRAGETASSEVRLRGAVLVHPFFWGPNLSDTEKEQNGFVDMFWRLVSPDVGAMQSHWVNWEAEGATPLTKLGCRRVMVCVAELDFIKKGKDYYEALKESGWEGKVEFVETEGEGHVFHLLNPDCEKARVFMEQVASFLNRV
>XP_011627915.2
METTDQPFKEYPPFVRIHNDGTVERHTGTQTLPPSPLSDAGVSSKDVVISPNVSARLYIPHSALSSTKKLPTLVYFHGGGFIIESPFSPHYHPYQDALAAKAGVIIVSVNYRLAPEHQLPAAYDDSWEAIKWTVGLSDEWLRDHADLDRLFLAGDSSGGNIVHQMAMRAGETASSEVRLRGVVLVHPFFWGPNLSDTENEQSGFVEKLWKLFSPDVGAMQSHWVNWEAEGATPLTKLGCRRVMVCVAELDFIKKKGKEYYEALKESGWEGKVELVETEGENHVFHLFKPDCEKARVFMEQVVSFLNQV
>XP_011627929.1
MASPANPKGILHEFPPFIRIYKDGTVELLIAANGEKLTTLLYFQGGAFVIESAFSPFYHRYLDALSAKANALIISVDYCLAPDHPLSTAYDDAWAAFQWIMDLSDPWLRDHADLDHLFLARDSAGANIAHRTTMRAGKSTGARVRRLVTIHPFFWGTDLKETARERSESVEKMSRFVCPKTNGLDDPQVNPGAEALERLGCRNMLVCVAGKDMSRERGRAYYEDVRRSGWEGVAEVMEIEEEDHIFHLFRPDCDNASLMMEQILMFLNND
>XP_011629233.1
MEAPKEILKNLPPFIRIYKDGTVERPLGTHTIPPSTLSAVGISSKDVVISPQVSARLYIPHSSLSSSPITKLATIVYFHGGAFVIGSPFSPFYNGYIETLSAKANALIVSVSYRLAPEHPLPTAYNDSWAAIEWTVSLSDEWLNDHADLNRIFLAGDSAGANITHQMAMRAGTKGSPIGLRGVVLVHPFFWGSDLSEEEEERSWSVNQMWTVACPTSDGIDDPWINPRAETAPPLKELGCQRVLVCLAGVDFLREKGKAYYEALRESGWEGVAEVVEVAEEGHAFHLFNQGCENAVKLMERIVDFISSGGTS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University