Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Lablab purpureus
Species name
Antaque (Lablab purpureus) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Lablab_purpureus.CHS.fa
Download
>Labpu164S10260_LABPU
MMMMMMVESGLEGLIYXRRHSTELSEKYLVGKIGVKESLLRHAVQRSEGKHARIYLPTHQFLSTHLNSPQLCAVPAYIXDQTTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLNEEILKDNPSLCAYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRASVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSETHLDSLVGQALFGDGAAAVIVGSDPLPVENPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLRLNPQKMEATRHVLSEYGNMSSACVLFIMDHMRKNSVQSGLATTGEGLDWGVLFGFGPGLTVETVVLRSVTL
>Labpu164S19980_LABPU
MVSVEELRKAQRAEGPATVMAIGTATPPNCVDQTTYPDYYFRITNSEHKTELKEKFQRMCKLYFTLQVSSSSSSFHFINSDKSMIKKRYMYLNEEILKDNPSLCAYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRASVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSETHLDSLVGQALFGDGAAAVIVGSDPLPVENPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLRLNPQKMEATRHVLSEYGNMSSACVLFIMDHMRKNSVQSGLATTGEGLDWGVLFGFGPGLTVETVVLRSVTL
>Labpu331S06926_LABPU
MPQGDSNGSSKQHAALTNARRVPNPGKATILAIGKAFPSQIIPQECLVEGYIRDTKCEDAYIKEKLERLCKNTTVKTRYTVMSKEILDKYPELATEGSPTIKQKLEIANPAVVEMATKASLCCIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLANELGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGANPVVGQESPFMELSYAVQKFLPETHNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLMAKSSVKDFNDLFWAVHPGGPAILNKLESVLKLSTDKLECSRKALMDYGNVSSNTIFYVMEYMREYLKDDGEEWGLGLAFGPGITFEGILLRSL
>Labpu673S17261_LABPU
MVTVEEIRNAQRSHGPATILAFGTATPSNCVSQEDYPDYYFRITNSEHMTDLKEKFKRMCEKSMIKKRYMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAMIIGADPDRKVERPIFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLTEAFAPIGINDWNSIFWVAHPGGPAILDQVEEKLGLKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKRSKEEEKGSTGEGLEWGVLFGFGPGLTVETVVLHSVPLRGE
>Labpu887S19168_LABPU
MIELSTFSNEMAHLEEIREKQRARGPATILAIGTATPTNCIYQSDFTDYYFRVTKSEHMTQLKAKLKRICEKSMIEKRYIHLTEKMLKENPNISTYEEPSLDARQDILVEEVPKLGEKAASKAIKEWGRPISDITHLIFCSTSGVDMPGADYQLVRLLGLKPSTKRFMLYHQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITVVTFRGPCETHLDSLVGQALFGDGASSVIVGSDPDTSIERPLFHLVSASETILPNSEGAIEGHLREVGLTFHLKDSVPQLIGENIEKSLEETFHPLGISDWNSLFWVTHPGGPAILKQIEATLGLNPDKLRATKQVLREYGNMSSACVLFILDEMRRWSLEEGKSSTGEGLKWGVLYGFGPGLTMETIALHSATIHPNN
>Labpu1502S09866_LABPU
MGEQGIWKGATKQGVNPGKATILALGKAFPHQLVMQDYLVDGYFRNTNCDNPELKQKLTRLCKTTTVKTRYVVMSEEILIKYPELVTEGVPTVKQRLEICNEAVTEMAIEASQACIKNWGGSLSDITHLVYVSSSEARLPGGDLYLAKGLGLSPDTQRIMLYFAGCSGGVAGLRVAKDVAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPILEYEKPLFELHTAVQEFLPHTEKKIDGRLTEEGISFKLARELPQIIEDSVEAFCDKLMSVVGFQNKEYNKLFWAVHPGGPAILNRVEKRLDLLPEKLSASRRALMDYGNASSNTIVYVLEYMIEEGLKIRKDDRGYSEWGLILAFGPGITFEGILARNLCT
>Labpu1958S11673_LABPU
MVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSDKSMIKKRYMHLTEDILKENPNMCAYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPEIEKPLFELVWTAQTIAPDSDGAIDGHLREAGLTFHLLKDVPGIVSKNIGKALSEAFDPLNISDYNSIFWIAHPGGPAILDQVEEKLGLKAEKMKATRDVLSEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETVVLHSKTKMVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSDKSMIKKRYMYLTEEILKENPNMCAYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPEIEKPLFELVWTAQTIAPDSDGAIDGHLREAGLTFHLLKDVPGIVSKNIGKALSEAFDPLKISDYNSIFWIAHPGGPAILDQVEEKLGLKAEKMKATRDVLSEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETVVLHSKSKMVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSDKSMIKKRYMHLTEDILKENPNMCAYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPEIEKPLFELVWTAQTIAPDSDGAIDGHLREAGLTFHLLKDVPGIVSKNIGKALSEAFDPLNISDYNSIFWIAHPGGPAILDQVEEKLGLKAEKMKATRDVLSEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETEANKMVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSEHMTDLKEKFQRIEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAT
>Labpu3909S07041_LABPU
MANVDQIHKAQRAEGAATILAISIASPPNWKRLMIKKGYMQLIEEIGREHPNIGEHMPPSLNARQELVVMEVPRLGKEAATKAIKEWGQPKSKITHLIFCTTSGNDMPTTDSHADIVGQSLFGDGAAAVIVGSDIIPNVSNTELAIALHLREAGLAFHVLKGAPKLITNNIENVLVEAFQPISLYQVEEKVGLKPQKLRASPHVLGEYGNMERACVFFTMDEMRKNTEEPELSTTPINIYY
>Labpu4332S15082_LABPU
MDESLGCSEMAYLEEVRAKQRAGGPATILAIATATPPNCIHQDDFPDFYFRITKSDHMTQLKAKFKRICEKSMVKTRYIHLTEEMLNEEPKLGSYKASLDARQEILIKEIPKLGEKAASKAIEEWGREKSDITHLVFCSYAGMDMPGADYQLVKLLGLKPSTKRFMLYHQGCFAGAAALRLAKDLAENNVGARVLVVCSEITIAAFRGPSESHVDTLVGQALFGDGASSAIVGSDPDTSVERPLFHMVSASQTIVPNSEGAMEGHLREMGLTFHLKDSVPTLIGDNIEKRLEESLEAFGVSDWNSLFWVVHPGGPAILNQIEAKVRLKPDKLKASREVLSAYGNMSSACVLFVLDEMRRKSLKEGKATTGEGLQWGVLFGFGPGLTLETIVLHSAITDSASGS
>Labpu3574S02841_LABPU
MVSVEEIRKAQRAEGPATVMAIGTANPPNCMDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMINKRYMYLNEEILKENPSLCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPLPVENPLFQLVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEEALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLGLKPQKLEATRQVLSEYGNMSSACVLFILDQMRKKSIENGLGTTGEGLDWGVLFGFGPGLTVETVVLRSVTV
MMMMMMVESGLEGLIYXRRHSTELSEKYLVGKIGVKESLLRHAVQRSEGKHARIYLPTHQFLSTHLNSPQLCAVPAYIXDQTTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLNEEILKDNPSLCAYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRASVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSETHLDSLVGQALFGDGAAAVIVGSDPLPVENPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLRLNPQKMEATRHVLSEYGNMSSACVLFIMDHMRKNSVQSGLATTGEGLDWGVLFGFGPGLTVETVVLRSVTL
>Labpu164S19980_LABPU
MVSVEELRKAQRAEGPATVMAIGTATPPNCVDQTTYPDYYFRITNSEHKTELKEKFQRMCKLYFTLQVSSSSSSFHFINSDKSMIKKRYMYLNEEILKDNPSLCAYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRASVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSETHLDSLVGQALFGDGAAAVIVGSDPLPVENPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLRLNPQKMEATRHVLSEYGNMSSACVLFIMDHMRKNSVQSGLATTGEGLDWGVLFGFGPGLTVETVVLRSVTL
>Labpu331S06926_LABPU
MPQGDSNGSSKQHAALTNARRVPNPGKATILAIGKAFPSQIIPQECLVEGYIRDTKCEDAYIKEKLERLCKNTTVKTRYTVMSKEILDKYPELATEGSPTIKQKLEIANPAVVEMATKASLCCIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLANELGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGANPVVGQESPFMELSYAVQKFLPETHNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLMAKSSVKDFNDLFWAVHPGGPAILNKLESVLKLSTDKLECSRKALMDYGNVSSNTIFYVMEYMREYLKDDGEEWGLGLAFGPGITFEGILLRSL
>Labpu673S17261_LABPU
MVTVEEIRNAQRSHGPATILAFGTATPSNCVSQEDYPDYYFRITNSEHMTDLKEKFKRMCEKSMIKKRYMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAMIIGADPDRKVERPIFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLTEAFAPIGINDWNSIFWVAHPGGPAILDQVEEKLGLKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKRSKEEEKGSTGEGLEWGVLFGFGPGLTVETVVLHSVPLRGE
>Labpu887S19168_LABPU
MIELSTFSNEMAHLEEIREKQRARGPATILAIGTATPTNCIYQSDFTDYYFRVTKSEHMTQLKAKLKRICEKSMIEKRYIHLTEKMLKENPNISTYEEPSLDARQDILVEEVPKLGEKAASKAIKEWGRPISDITHLIFCSTSGVDMPGADYQLVRLLGLKPSTKRFMLYHQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITVVTFRGPCETHLDSLVGQALFGDGASSVIVGSDPDTSIERPLFHLVSASETILPNSEGAIEGHLREVGLTFHLKDSVPQLIGENIEKSLEETFHPLGISDWNSLFWVTHPGGPAILKQIEATLGLNPDKLRATKQVLREYGNMSSACVLFILDEMRRWSLEEGKSSTGEGLKWGVLYGFGPGLTMETIALHSATIHPNN
>Labpu1502S09866_LABPU
MGEQGIWKGATKQGVNPGKATILALGKAFPHQLVMQDYLVDGYFRNTNCDNPELKQKLTRLCKTTTVKTRYVVMSEEILIKYPELVTEGVPTVKQRLEICNEAVTEMAIEASQACIKNWGGSLSDITHLVYVSSSEARLPGGDLYLAKGLGLSPDTQRIMLYFAGCSGGVAGLRVAKDVAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPILEYEKPLFELHTAVQEFLPHTEKKIDGRLTEEGISFKLARELPQIIEDSVEAFCDKLMSVVGFQNKEYNKLFWAVHPGGPAILNRVEKRLDLLPEKLSASRRALMDYGNASSNTIVYVLEYMIEEGLKIRKDDRGYSEWGLILAFGPGITFEGILARNLCT
>Labpu1958S11673_LABPU
MVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSDKSMIKKRYMHLTEDILKENPNMCAYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPEIEKPLFELVWTAQTIAPDSDGAIDGHLREAGLTFHLLKDVPGIVSKNIGKALSEAFDPLNISDYNSIFWIAHPGGPAILDQVEEKLGLKAEKMKATRDVLSEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETVVLHSKTKMVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSDKSMIKKRYMYLTEEILKENPNMCAYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPEIEKPLFELVWTAQTIAPDSDGAIDGHLREAGLTFHLLKDVPGIVSKNIGKALSEAFDPLKISDYNSIFWIAHPGGPAILDQVEEKLGLKAEKMKATRDVLSEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETVVLHSKSKMVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSDKSMIKKRYMHLTEDILKENPNMCAYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPEIEKPLFELVWTAQTIAPDSDGAIDGHLREAGLTFHLLKDVPGIVSKNIGKALSEAFDPLNISDYNSIFWIAHPGGPAILDQVEEKLGLKAEKMKATRDVLSEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETEANKMVSVSEIRQAQRAEGPANILAIGTATPPNCIDQSTYPDYYFRITNSEHMTDLKEKFQRIEYGNMSSACVLFILDEMRRKSAENGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAT
>Labpu3909S07041_LABPU
MANVDQIHKAQRAEGAATILAISIASPPNWKRLMIKKGYMQLIEEIGREHPNIGEHMPPSLNARQELVVMEVPRLGKEAATKAIKEWGQPKSKITHLIFCTTSGNDMPTTDSHADIVGQSLFGDGAAAVIVGSDIIPNVSNTELAIALHLREAGLAFHVLKGAPKLITNNIENVLVEAFQPISLYQVEEKVGLKPQKLRASPHVLGEYGNMERACVFFTMDEMRKNTEEPELSTTPINIYY
>Labpu4332S15082_LABPU
MDESLGCSEMAYLEEVRAKQRAGGPATILAIATATPPNCIHQDDFPDFYFRITKSDHMTQLKAKFKRICEKSMVKTRYIHLTEEMLNEEPKLGSYKASLDARQEILIKEIPKLGEKAASKAIEEWGREKSDITHLVFCSYAGMDMPGADYQLVKLLGLKPSTKRFMLYHQGCFAGAAALRLAKDLAENNVGARVLVVCSEITIAAFRGPSESHVDTLVGQALFGDGASSAIVGSDPDTSVERPLFHMVSASQTIVPNSEGAMEGHLREMGLTFHLKDSVPTLIGDNIEKRLEESLEAFGVSDWNSLFWVVHPGGPAILNQIEAKVRLKPDKLKASREVLSAYGNMSSACVLFVLDEMRRKSLKEGKATTGEGLQWGVLFGFGPGLTLETIVLHSAITDSASGS
>Labpu3574S02841_LABPU
MVSVEEIRKAQRAEGPATVMAIGTANPPNCMDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMINKRYMYLNEEILKENPSLCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPLPVENPLFQLVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEEALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLGLKPQKLEATRQVLSEYGNMSSACVLFILDQMRKKSIENGLGTTGEGLDWGVLFGFGPGLTVETVVLRSVTV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University