Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Kobresia littledalei
Species name
Carex littledalei is a species of monocot in the family Cyperaceae (sedge family).
Species info
Gene sequence info
Kobresia_littledalei.COMT.fa
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>rna-gnl|WGS:SWLB|mrna.FCM35_KLT00010
MTIDRILRLLASYNIVACTAETEDNGKKVTWRYGPAPVCKWLTKNDEGVEQVAGDMLKKLPTDDAILIKYTLHNCSNKHCVTILNNCYKALPDYGKVIIVERILQVNPTVTPESQGVFDV
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT00008
MGPTAAGVPAVSERRNSVDNDACMLAWQLTTASILPMTLKTALELDLLEILVSGCGGPSGKLTMTAADVASHLDAGNPQAAMTLDRILRLLAAYNIVTCSSETDDEGKLLTWHYRPAPVCKWLTKNEEGVSMASLVLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGVTPFEYFGKDARCNQLFNEGMKSQTVIITKKLIEFYPGFDDVNILVDVGGGTGATLGIITSSYNHIKGINFDLPHVIHTAPALPGVEHVAGDMLEEVPTGDAILIKYTLHDWSDEHCMTILKNCYRALPDNAKVIIVERILPVNPSAAPESQGVFDVDLVMLLQTPGGKQRTQNEFEALSKEAGFSSLKATHVFANTWAIELKKIRNII
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT00007
MGSHGLDVAVASQKDYTDEEACMYALQLSSASILPMTLKAAIELDVLEILVKGCGGHFSNPVMTATDVASHLKTNNPQAAEMLDRMLSLLASYNVIKCEVEINDDGKNVTRRYGPAKVCKWLTKNEDGVSMAALALMNQDKVLMESWYYLKDAVLEGCVPFNKAHGMTAFEYNAKDQRVSRLFNEGMKSHSIILTKSFLQLYHGFNDINTLVDVGGGVGATLNMITSKYPKIKGINFDLSHVIADAPPYHGVEHVGGDMFASIPTADAIMMKSILHDWSDEHCEKILKNCYKALPENGKVIILDCIVPANPDATARCAFHVDMLMLAYNPGGKERTEKEFRSLAEGAGFSGFKTTHVSADTWIIEVSK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT16362
MEITIIKNLSVAYINTFALKCAVDLDISGRLQAYGQAMPLNELARSIPIPPEKDSMLGRLMALLVHQGIFAQSEEGYLLTPVSELLLIDGSNMGAFVHNSTNENFIRSWGRLSEVFTDTGASTLFQKANYGKGVWEVLKETSNRGNLFNEAMASHTKPLMRGLVKTYPHIFDGLHSLVDVGGGTGTAVKIIAEAFPGLRCTVFDLPNVVAEASKNDTFDVVGGDMFEKIPPADAIFLKNILHDWSNEDCIRILKRCKEAIESGKSNGGKVIVVDIIIDLESDDPKAVETSLLFDINMMCCFGSKERRKQEWHDIILAAGYSGYKIYPSRLGVDAGFPYNQYLASTFLGPSFNTHIQMEITIIKNLSVAYINTFALKCAVDLDISGRIQAYGQAMPLNELARSIPIPPKKDSMLARLMALLVHQGIFAQSEAGYLLTPVSELLLIDGSNMGAFVHNSTNENFIRSWGRLSEVFTDTGASTLFQKANYGKGVWEVLKETSNRGNLFNEAMASHTKPLMRGLVATYPHIFDGLHSLVDVGGGTGTAVKIIAEAFPGLRCTVFDLPHVVAEASKNDSFDVVGGDMFEKIPPADAIFLKNVLHDWSDEDCVRILKRCKEAIESSKSNGGKVIVVDIIIDLESDDPKAVETSLLFDINMMCCFGSKERNKQEWHNIIMGAGYSGYKICPSRLGVDALIELYP
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT17657
MGAFVRFCTALAVTKHLCVMSEWFKNGDDGSSVYIMDNDGKKFFDIAREKPEIGNLFNEAMASHSKQKIGDLVTSYPHIFDGLNSLVDVGGGTGTAAKIIADAFPSLRCTVLDLPHVVEKASESNSINVVAGDMFEKIPSADAILLNNVLHDWHGEDCVRILKRCKDAIEPRKDGSKVIVVDIIQDFENNNPKATETGFLFDILMMTSHGTKERTKQEWHDLIIGAGYSGYTIYPTRLGIDCVMELYP
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT06420
MDSMTSTHTLVDVGGGVGVILSMITSKYPKIKGINFDLPQRAVLIALCTQILPRYVHYSHLSFSIKKQRKVHYDVMSVMVSGRIGVEHVGGDMFASIPIGDAICIMMKWILHDWSDEHCQNILKNCYKALPENGKVIILDCIVPTNPDATARCAFHNYMAKRASYIYK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21764
MYSQAAMMLDRILRLLAAYNIVTCSSETDDEGKLLTWHYGPAPVCKWLTKNEEGVSMASLVLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGVTPFEYFGKDARCNQLFNEGMKSQTVIITKKLIEFYPGFDDVNILVDVGGGTGATLGIITSSYNHIKGVEHVGGDMLEEVPTGDAILIKCTLHDWSDEHCMTILKNCYRALPDNAKVIIVERILPVNPSAAPESQGVFDVDLVMLLQTPGGKQRTQNEFEALSKEAGFSSLKATHVFANTWAIELKK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21767
MGSHGLDVAVASQKDYTDEEACMYALQLSTASILPMTLKAAIELDLLEILVKGCGGHFSNPVMTATDVASHLKTNNPQAAEMLDRMLRLLASYNVIKCEVEINDDGQNVTRRYGPAKVCKWLTKNEDGISMAGLALMNQDKVLMESWYYLKDAVLEGCVPFNKAHGMTAFEYNAKDQRVSRLFNEGMKSHSIILTKSFLQVYHGFNDINTLVDVGGGVGATLNMITSKYPKIKGINFDLSHVIADAPPYHGVEHVGGDMFASIPTADAIMMKSILHDWSDEHCEKILKNCYKALPENGKVIILDCIVPANPDATARCAFHVDMLMLAYNPGGKERTEKEFRSLAEGAGFSGFKTTHVSADTWIIEVSK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21762
MSQLPKKNFTTRYHLKDSVLDGGIPFNKAYGMMSFEYLGKDTRCNRLFNEGMKSQTIIITKAYFAHNHLRA
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21761
MLKKVPTGDAILIKYTLHNCSNKHCVAILKNCYKALPDNGKVIIVERILPVNPTVTPESQGVFDVDLIMLLQTPGGKERTQIEFEAMATEADFSSLNATHIFANTWAIELKK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT22267
MGSAGGDVHVAMVPRDEADEEACMHALQLASASILPMTLKAAIELDVLEILVKGCGGPYGKPIMTPVDVAAHLKTENPQAAVMLDRMLRLLASYNVVACSVEVEDDGNKVIRKYGPAPVCKWLTKNEDGVSMAPLVLMNQDKAQGVFHLDLIMLAHNPGGKERTMKEFEALAKEVGFASFKANYVYANSWALEFTK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT22266
MGSIDIAAAPQKVQVDEEACLYSLQLASSCILPMTLKAAVELDLLDILVAGCGGPSGKPTMTATDVANHLKTENPQAAAMLDRMLRVLASYNVVKCAAEISDDGKTVTRRYGPAPVCAFLTKNEDGFSIAPLLLMNHDKVLMESWYACRSLRCRVFKFVLPFELSHE
MTIDRILRLLASYNIVACTAETEDNGKKVTWRYGPAPVCKWLTKNDEGVEQVAGDMLKKLPTDDAILIKYTLHNCSNKHCVTILNNCYKALPDYGKVIIVERILQVNPTVTPESQGVFDV
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT00008
MGPTAAGVPAVSERRNSVDNDACMLAWQLTTASILPMTLKTALELDLLEILVSGCGGPSGKLTMTAADVASHLDAGNPQAAMTLDRILRLLAAYNIVTCSSETDDEGKLLTWHYRPAPVCKWLTKNEEGVSMASLVLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGVTPFEYFGKDARCNQLFNEGMKSQTVIITKKLIEFYPGFDDVNILVDVGGGTGATLGIITSSYNHIKGINFDLPHVIHTAPALPGVEHVAGDMLEEVPTGDAILIKYTLHDWSDEHCMTILKNCYRALPDNAKVIIVERILPVNPSAAPESQGVFDVDLVMLLQTPGGKQRTQNEFEALSKEAGFSSLKATHVFANTWAIELKKIRNII
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT00007
MGSHGLDVAVASQKDYTDEEACMYALQLSSASILPMTLKAAIELDVLEILVKGCGGHFSNPVMTATDVASHLKTNNPQAAEMLDRMLSLLASYNVIKCEVEINDDGKNVTRRYGPAKVCKWLTKNEDGVSMAALALMNQDKVLMESWYYLKDAVLEGCVPFNKAHGMTAFEYNAKDQRVSRLFNEGMKSHSIILTKSFLQLYHGFNDINTLVDVGGGVGATLNMITSKYPKIKGINFDLSHVIADAPPYHGVEHVGGDMFASIPTADAIMMKSILHDWSDEHCEKILKNCYKALPENGKVIILDCIVPANPDATARCAFHVDMLMLAYNPGGKERTEKEFRSLAEGAGFSGFKTTHVSADTWIIEVSK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT16362
MEITIIKNLSVAYINTFALKCAVDLDISGRLQAYGQAMPLNELARSIPIPPEKDSMLGRLMALLVHQGIFAQSEEGYLLTPVSELLLIDGSNMGAFVHNSTNENFIRSWGRLSEVFTDTGASTLFQKANYGKGVWEVLKETSNRGNLFNEAMASHTKPLMRGLVKTYPHIFDGLHSLVDVGGGTGTAVKIIAEAFPGLRCTVFDLPNVVAEASKNDTFDVVGGDMFEKIPPADAIFLKNILHDWSNEDCIRILKRCKEAIESGKSNGGKVIVVDIIIDLESDDPKAVETSLLFDINMMCCFGSKERRKQEWHDIILAAGYSGYKIYPSRLGVDAGFPYNQYLASTFLGPSFNTHIQMEITIIKNLSVAYINTFALKCAVDLDISGRIQAYGQAMPLNELARSIPIPPKKDSMLARLMALLVHQGIFAQSEAGYLLTPVSELLLIDGSNMGAFVHNSTNENFIRSWGRLSEVFTDTGASTLFQKANYGKGVWEVLKETSNRGNLFNEAMASHTKPLMRGLVATYPHIFDGLHSLVDVGGGTGTAVKIIAEAFPGLRCTVFDLPHVVAEASKNDSFDVVGGDMFEKIPPADAIFLKNVLHDWSDEDCVRILKRCKEAIESSKSNGGKVIVVDIIIDLESDDPKAVETSLLFDINMMCCFGSKERNKQEWHNIIMGAGYSGYKICPSRLGVDALIELYP
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT17657
MGAFVRFCTALAVTKHLCVMSEWFKNGDDGSSVYIMDNDGKKFFDIAREKPEIGNLFNEAMASHSKQKIGDLVTSYPHIFDGLNSLVDVGGGTGTAAKIIADAFPSLRCTVLDLPHVVEKASESNSINVVAGDMFEKIPSADAILLNNVLHDWHGEDCVRILKRCKDAIEPRKDGSKVIVVDIIQDFENNNPKATETGFLFDILMMTSHGTKERTKQEWHDLIIGAGYSGYTIYPTRLGIDCVMELYP
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT06420
MDSMTSTHTLVDVGGGVGVILSMITSKYPKIKGINFDLPQRAVLIALCTQILPRYVHYSHLSFSIKKQRKVHYDVMSVMVSGRIGVEHVGGDMFASIPIGDAICIMMKWILHDWSDEHCQNILKNCYKALPENGKVIILDCIVPTNPDATARCAFHNYMAKRASYIYK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21764
MYSQAAMMLDRILRLLAAYNIVTCSSETDDEGKLLTWHYGPAPVCKWLTKNEEGVSMASLVLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGVTPFEYFGKDARCNQLFNEGMKSQTVIITKKLIEFYPGFDDVNILVDVGGGTGATLGIITSSYNHIKGVEHVGGDMLEEVPTGDAILIKCTLHDWSDEHCMTILKNCYRALPDNAKVIIVERILPVNPSAAPESQGVFDVDLVMLLQTPGGKQRTQNEFEALSKEAGFSSLKATHVFANTWAIELKK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21767
MGSHGLDVAVASQKDYTDEEACMYALQLSTASILPMTLKAAIELDLLEILVKGCGGHFSNPVMTATDVASHLKTNNPQAAEMLDRMLRLLASYNVIKCEVEINDDGQNVTRRYGPAKVCKWLTKNEDGISMAGLALMNQDKVLMESWYYLKDAVLEGCVPFNKAHGMTAFEYNAKDQRVSRLFNEGMKSHSIILTKSFLQVYHGFNDINTLVDVGGGVGATLNMITSKYPKIKGINFDLSHVIADAPPYHGVEHVGGDMFASIPTADAIMMKSILHDWSDEHCEKILKNCYKALPENGKVIILDCIVPANPDATARCAFHVDMLMLAYNPGGKERTEKEFRSLAEGAGFSGFKTTHVSADTWIIEVSK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21762
MSQLPKKNFTTRYHLKDSVLDGGIPFNKAYGMMSFEYLGKDTRCNRLFNEGMKSQTIIITKAYFAHNHLRA
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT21761
MLKKVPTGDAILIKYTLHNCSNKHCVAILKNCYKALPDNGKVIIVERILPVNPTVTPESQGVFDVDLIMLLQTPGGKERTQIEFEAMATEADFSSLNATHIFANTWAIELKK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT22267
MGSAGGDVHVAMVPRDEADEEACMHALQLASASILPMTLKAAIELDVLEILVKGCGGPYGKPIMTPVDVAAHLKTENPQAAVMLDRMLRLLASYNVVACSVEVEDDGNKVIRKYGPAPVCKWLTKNEDGVSMAPLVLMNQDKAQGVFHLDLIMLAHNPGGKERTMKEFEALAKEVGFASFKANYVYANSWALEFTK
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT22266
MGSIDIAAAPQKVQVDEEACLYSLQLASSCILPMTLKAAVELDLLDILVAGCGGPSGKPTMTATDVANHLKTENPQAAAMLDRMLRVLASYNVVKCAAEISDDGKTVTRRYGPAPVCAFLTKNEDGFSIAPLLLMNHDKVLMESWYACRSLRCRVFKFVLPFELSHE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University