Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Kobresia littledalei
Species name
Carex littledalei is a species of monocot in the family Cyperaceae (sedge family).
Species info
Gene sequence info
Kobresia_littledalei.CHS.fa
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>rna-gnl|WGS:SWLB|mrna.FCM35_KLT17351
MVNAQNTQHPQSPATVLAIGTATPANTLIQAEVPDRLFKAANSDQLTELKMKFTKICEASAIKKRHSIWTEEIVKQNPSIGIPNAPSLGARQNILINEVPKLGKFAAERAIKEWGQPISKLTHLIFCTTSGFAMPGFDCKLAHLLGLPSTINRYMLYHQGCHGGGTTLRLAKDLAQNNPSARVLVVCVEISLHGFHSPSQEHLDNLVTLAIFGDGASAMIVGTDPDLAAERPAFEIISANQKLLPNTSLAIVAELDEAGFMVHLSRNIAKYASENVESSLEEALAPLGITDWNSIFWVVHPGGVAILDGIEAKIKLNKEKLLASRNVLANYGNVQSATAMIVLDEMRKQSAKAQKSTTGEGLEWGVLLAFGPGMTVETIVLRAIPI
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT17349
MVNAKSTQHHQGPATVLAIGTAAPANTLIQAEVPDRLFKAANSDQLTELKMKFTKICEASAIKKRHSIWTEEIVNQNPSIGIPNAPSLGARQNILIHEVPKLGKLAAERAIKEWGQPISKLTHLIFCTTSGLAMPGFDCKLAHLLGLPSTINRYMLYHQGCHGGGTTLRLAKDLAQNNPSARVLVVCVEISLHGFHSPSEEHLDNLVTLAIFGDGASAMIVGADPDLAAERPAFEIISANQKLLPNTSLAIVAELDEAGFMVHLSRNIAKYASENVESCLEEALAPLGITDWNSIFWVVHPGGVAILDGIEAKMKLNKEKLLASRNVLANYGNVQSATAMIVLDKMRKQSAKAQKSTTGEGLEWGVLLAFGPGMTVETIVLRAIPI
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT19716
MNGDSSKIISNSNSRNARILALGKAFPQQLVMQDYLVDGFFKSTNCTDHELKQKLTRLCKTTTVKTRYVVMSEEILKNYPELATEGLPTVKQRLDISNKAVTEMATDASLSCIKAWGRPLSSITHLVYVSSSEARFPGGDLHLARGLGLNPDVRRVMLAFTGCSGGVAGLRVAKDLAENNPGSRVLLATSETTIVGFRPPSAQRPYDLVGVALFGDGAGAVILGADPVPGVEDPLFELSSSIQQYLPDTEKTIDGRLTEEGIKFQLGRELPQVIEMHVEEFCKKMLKDTICSGAEYNDLFWAVHPGGPAILSKVEGRLGLKPDKLSASRDALRDYGNASSNTIVYVLENMVEESKRKREKGEEYSEWGLILAFGPGITFEGILAKNLVC
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT06585
MSINVNSTVASNKAKILALGKAFPDNVLLQENLVNGFLRDTKSEDPVMREKLERLCKNTTVKRRFTVMSKEILDKYPELATEGTPTLKQRLEIANPAVVDMAAEAANACLAEWGRSASEITHLVYVSSSELRLPGGDLHLAARLGLRSDVSRVVLYYLGCYGGVTGLRVAKDLAENNPGSRVLLVTSETTIIGFRPPNMSRPYDLVGAALFGDGAAAVIIGSDPIATIEKPFLELHTAVQKFIPETHNVIDGRMSEEGINFKLGRELPHVIEENIEGFCKGLMSKTGLKEFNDLFWTVHPGGPAILNRLESCLGLKPEKLTSSRQALIDYGNVSSNTVFYVMDYMREELKKEGAAEWGLVLAFGPGVTFEGILVRRI
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT10248
MAQNNKKTVGGKATVLAIGTANPSNLIYQSDYPDYYFKATKSEHLTKLKQKLTRICTGTKIQKRHFYLTDEMLKDHPNLSTHKDQSLDSRNALITPGVMKLGKDAAEQALHEWGQPRSRITHLIFHTATGCVHLPGPDYQLINLLGLEPTVNRYMIYHNGCYAGGTVLRLAKDLAENNPGARILAICSESDQDFFRPPSDSLHTLVAQALFGDGAGAVIVGSDPDMSVERPLYEILSTGQSIIPGTEDVLGGHVAEAGFVMFMAPTVPMHITNNIRKCVSKAFEPLGISDWNSLFWIVHPGGQKILDGIETELKLEKEKLLPSRHVLAEFGNMASGSVIFVMDEMRKRSRKEGKATTGEGAEFGVLLGFGPGLTIETAVLRALTIPI
MVNAQNTQHPQSPATVLAIGTATPANTLIQAEVPDRLFKAANSDQLTELKMKFTKICEASAIKKRHSIWTEEIVKQNPSIGIPNAPSLGARQNILINEVPKLGKFAAERAIKEWGQPISKLTHLIFCTTSGFAMPGFDCKLAHLLGLPSTINRYMLYHQGCHGGGTTLRLAKDLAQNNPSARVLVVCVEISLHGFHSPSQEHLDNLVTLAIFGDGASAMIVGTDPDLAAERPAFEIISANQKLLPNTSLAIVAELDEAGFMVHLSRNIAKYASENVESSLEEALAPLGITDWNSIFWVVHPGGVAILDGIEAKIKLNKEKLLASRNVLANYGNVQSATAMIVLDEMRKQSAKAQKSTTGEGLEWGVLLAFGPGMTVETIVLRAIPI
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT17349
MVNAKSTQHHQGPATVLAIGTAAPANTLIQAEVPDRLFKAANSDQLTELKMKFTKICEASAIKKRHSIWTEEIVNQNPSIGIPNAPSLGARQNILIHEVPKLGKLAAERAIKEWGQPISKLTHLIFCTTSGLAMPGFDCKLAHLLGLPSTINRYMLYHQGCHGGGTTLRLAKDLAQNNPSARVLVVCVEISLHGFHSPSEEHLDNLVTLAIFGDGASAMIVGADPDLAAERPAFEIISANQKLLPNTSLAIVAELDEAGFMVHLSRNIAKYASENVESCLEEALAPLGITDWNSIFWVVHPGGVAILDGIEAKMKLNKEKLLASRNVLANYGNVQSATAMIVLDKMRKQSAKAQKSTTGEGLEWGVLLAFGPGMTVETIVLRAIPI
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT19716
MNGDSSKIISNSNSRNARILALGKAFPQQLVMQDYLVDGFFKSTNCTDHELKQKLTRLCKTTTVKTRYVVMSEEILKNYPELATEGLPTVKQRLDISNKAVTEMATDASLSCIKAWGRPLSSITHLVYVSSSEARFPGGDLHLARGLGLNPDVRRVMLAFTGCSGGVAGLRVAKDLAENNPGSRVLLATSETTIVGFRPPSAQRPYDLVGVALFGDGAGAVILGADPVPGVEDPLFELSSSIQQYLPDTEKTIDGRLTEEGIKFQLGRELPQVIEMHVEEFCKKMLKDTICSGAEYNDLFWAVHPGGPAILSKVEGRLGLKPDKLSASRDALRDYGNASSNTIVYVLENMVEESKRKREKGEEYSEWGLILAFGPGITFEGILAKNLVC
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT06585
MSINVNSTVASNKAKILALGKAFPDNVLLQENLVNGFLRDTKSEDPVMREKLERLCKNTTVKRRFTVMSKEILDKYPELATEGTPTLKQRLEIANPAVVDMAAEAANACLAEWGRSASEITHLVYVSSSELRLPGGDLHLAARLGLRSDVSRVVLYYLGCYGGVTGLRVAKDLAENNPGSRVLLVTSETTIIGFRPPNMSRPYDLVGAALFGDGAAAVIIGSDPIATIEKPFLELHTAVQKFIPETHNVIDGRMSEEGINFKLGRELPHVIEENIEGFCKGLMSKTGLKEFNDLFWTVHPGGPAILNRLESCLGLKPEKLTSSRQALIDYGNVSSNTVFYVMDYMREELKKEGAAEWGLVLAFGPGVTFEGILVRRI
>rna-gnl|WGS:SWLB|mrna.FCM35_KLT10248
MAQNNKKTVGGKATVLAIGTANPSNLIYQSDYPDYYFKATKSEHLTKLKQKLTRICTGTKIQKRHFYLTDEMLKDHPNLSTHKDQSLDSRNALITPGVMKLGKDAAEQALHEWGQPRSRITHLIFHTATGCVHLPGPDYQLINLLGLEPTVNRYMIYHNGCYAGGTVLRLAKDLAENNPGARILAICSESDQDFFRPPSDSLHTLVAQALFGDGAGAVIVGSDPDMSVERPLYEILSTGQSIIPGTEDVLGGHVAEAGFVMFMAPTVPMHITNNIRKCVSKAFEPLGISDWNSLFWIVHPGGQKILDGIETELKLEKEKLLPSRHVLAEFGNMASGSVIFVMDEMRKRSRKEGKATTGEGAEFGVLLGFGPGLTIETAVLRALTIPI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University