Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Kandelia obovata
Species name
Kandelia obovata is a species of eudicot in the family Rhizophoraceae (red mangrove family).
Species info
Gene sequence info
Kandelia_obovata.COMT.fa
Download
>mrna:Maker00011069
MGSVGETQMTPAVVSDEEANLFAIQLTSASVLPMVLKSAIELDLLEIIAKAGPGAYLSPSDIACQLPTKNPDAAVLLDRILRLLASYSIVTCSLQTRPDGKVERLYGLAPVCKFLTKNEDGVSLAALSLMNQDKVLMESWYHVKDTVLEGGIPFNKAHGMTSFEYHGKDLRFNKVFNKGMSDHSTVTMKKILETYKGFEGLSSVVDVGGGTGAVLSMIISKYPTLKGINFDLPHVIEDAPPYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKNCYDALPANGKVVVAECILPEGPDASLATKCVVHVDIIMLAHNPGGKERTQKEFEALAKEAGFQGFTVMCSAFNTYIMEFLKKA
>mrna:Maker00011171
MSPSFIEEVVKPGNEEDADCLFAMQLTVSSLFDVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTPDTPVIIDRLLRLMASYSILTCSLVNDKEGHPLRFYGLGPVCKYFTRDEDGVSFAPVFQSYSQFAIDSCYQMKGAVLEGGTPIMRSHGKHVFEHTNDEFRSLFNEAMYNNTMIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPRIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKCVLHDWADKECVKILKNCYDALPEIGKVIAVESVLPELPEDDFVSKQSYNFDVAMFMANPGGKERTKRELEALAKEAGFAAMEVTCRAYSSWVIVFYKRA
>mrna:Maker00011096
MSPSFIEEVVKPGNEEDADCLFAMQLTVSSLFDVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTPDTPVIIDRLLRLMASYSILTCSLVNDKEGHPLRFYGLGPVCKYFTRDEDGVSFAPVFQSYSQFAIDSCYQMKGAVLEGGTPIMRSHGKHVFEHTNDEFRSLFNEAMYNNTMIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPRIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKCVLHDWADKECVKILKNCYDALPEIGKVIAVESVLPELPEDDFVSKQSYNFDVAMFMANPGGKERTKRELEALAKEAGFAAMEVTCRAYSSWVIVFYKRA
>mrna:Maker00011301
MSPYVEEVVKAANEDDADCVFAMQLTVSSLFDVALRTVIELGLFEIMAKAGKGAQLSASEIASHLPTKTPDASVIIDRLLRLMASHSILTCSLVNDREGHPLRFYGLGPVCKYFTRDEDGVSFAPLFQFLSQFAIDSCYQMKDAILEGGTPIMRSHGKHVFENTNDEFQSLFNEAMYNNTVIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPHIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKSVLHDWADKECVEILKNCYDALPETGKVIALESLLPELLENNFVSKHGYILDVAMFMAIPGGKERTKKELEALAKEAGFAAMEVVCRAYSFWVIVFTKGCDEFNSISPLDPVGE
>mrna:Maker00011403
MSPSFIEEVVKPGNEEDADCLFAMQLTVSSLFDVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTPDTPVIIDRLLRLMASYSILTCSLVNDKEGHPLRFYGLGPVCKYFTRDEDGVSFAPVFQSYSQFAIDSCYQMKGAVLEGGTPIMRSHGKHVFEHTNDEFRSLFNEAMYNNTMIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPRIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKCVLHDWADKECVKILKNCYDALPEIGKVIAVESVLPELPEDDFVSKQSYNFDVAMFMANPGGKERTKRELEALAKEAGFAAMEVTCRAYSSWVIVFYKRA
>mrna:Maker00003318
MSEIQNQHEKEETGKQAVLLANAGILPMVLKSALELNIIDILSTATSGGAWLSPSEVAARIPTKNPDAPSLIDRMLPFLASFNVIKCSVSTSENGELEGAYGAAPICKFLSRNQEDEGGSIAPLILLHHDEVFHKSWYHLNDVILEGGIPFNRAYGMTAFEYPATDQRFNRVFNQAMSNHTTLIIKKILEAYKGFDGLNVLVDVGGGVGVALKMIVSRHPHIKGINYDLAHVLADAPSYPEVEHVGGDMFVSVPKGDAILMKWILHDWTDEHCLKLLSNCWEALPINGKVIIVESILPEAPERDVSSQIVFGQDLFMLAQNPGGKERSQKEFDALAKKSGFSGCEVMCPAYNSWVMEFRKRS
>mrna:Maker00003465
MLEHHALQLELQASVMAIVRRYRLSDVVLEGGIPFDRAHGTSEFEYTATDPRFNKLFNQGMSNCTTMVMKKMLEVYKGFDGINVLVDVGGGIGANLKMILSKHPHIKGINYDLAHVVAGASSHPGIEFVGGDMFVSVPKGDAILMKWVLHDWSDEHCLKVLKNCCQALPSNGKVILVELILPRTPEKDTSARIGFGQDLLLLAHNDGGRERTQKDFDGLAKKSGFSGCKVMCSAYDHWVMELHKKA
>mrna:Maker00016445
MEDESSESRNRARLGIIGLTNLISIPMSLQAIVRLNVADAIWQGGANSPLSASEILSCVHPSGGDADNLQRILRMLASYGVFHEHLRSDGSERRYSLTDIGKTLVTDGDGLSYAPYVLQHHQEALIQAWGLVHEAVLDPTTNPFVKANGEAAYIYYGKQPAMNSLMQKAMAGISVPFMKALLEGYDGFQGVERLVDVGGSAGDCLRMIIKKYPGIRQGINFDLPDVVARAPHIPCVSHVGGDMLKSIPEGDAIFMKWILSTWAYDECKKIMENCYKVLPAGGKLIACEPVLPENPDDSHRTRTLLENDLFIMTIYGAKGKVRTEQEFERLGLAVGFSQFRALYIDYFFTVLEFQK
MGSVGETQMTPAVVSDEEANLFAIQLTSASVLPMVLKSAIELDLLEIIAKAGPGAYLSPSDIACQLPTKNPDAAVLLDRILRLLASYSIVTCSLQTRPDGKVERLYGLAPVCKFLTKNEDGVSLAALSLMNQDKVLMESWYHVKDTVLEGGIPFNKAHGMTSFEYHGKDLRFNKVFNKGMSDHSTVTMKKILETYKGFEGLSSVVDVGGGTGAVLSMIISKYPTLKGINFDLPHVIEDAPPYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKNCYDALPANGKVVVAECILPEGPDASLATKCVVHVDIIMLAHNPGGKERTQKEFEALAKEAGFQGFTVMCSAFNTYIMEFLKKA
>mrna:Maker00011171
MSPSFIEEVVKPGNEEDADCLFAMQLTVSSLFDVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTPDTPVIIDRLLRLMASYSILTCSLVNDKEGHPLRFYGLGPVCKYFTRDEDGVSFAPVFQSYSQFAIDSCYQMKGAVLEGGTPIMRSHGKHVFEHTNDEFRSLFNEAMYNNTMIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPRIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKCVLHDWADKECVKILKNCYDALPEIGKVIAVESVLPELPEDDFVSKQSYNFDVAMFMANPGGKERTKRELEALAKEAGFAAMEVTCRAYSSWVIVFYKRA
>mrna:Maker00011096
MSPSFIEEVVKPGNEEDADCLFAMQLTVSSLFDVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTPDTPVIIDRLLRLMASYSILTCSLVNDKEGHPLRFYGLGPVCKYFTRDEDGVSFAPVFQSYSQFAIDSCYQMKGAVLEGGTPIMRSHGKHVFEHTNDEFRSLFNEAMYNNTMIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPRIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKCVLHDWADKECVKILKNCYDALPEIGKVIAVESVLPELPEDDFVSKQSYNFDVAMFMANPGGKERTKRELEALAKEAGFAAMEVTCRAYSSWVIVFYKRA
>mrna:Maker00011301
MSPYVEEVVKAANEDDADCVFAMQLTVSSLFDVALRTVIELGLFEIMAKAGKGAQLSASEIASHLPTKTPDASVIIDRLLRLMASHSILTCSLVNDREGHPLRFYGLGPVCKYFTRDEDGVSFAPLFQFLSQFAIDSCYQMKDAILEGGTPIMRSHGKHVFENTNDEFQSLFNEAMYNNTVIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPHIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKSVLHDWADKECVEILKNCYDALPETGKVIALESLLPELLENNFVSKHGYILDVAMFMAIPGGKERTKKELEALAKEAGFAAMEVVCRAYSFWVIVFTKGCDEFNSISPLDPVGE
>mrna:Maker00011403
MSPSFIEEVVKPGNEEDADCLFAMQLTVSSLFDVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTPDTPVIIDRLLRLMASYSILTCSLVNDKEGHPLRFYGLGPVCKYFTRDEDGVSFAPVFQSYSQFAIDSCYQMKGAVLEGGTPIMRSHGKHVFEHTNDEFRSLFNEAMYNNTMIIMKKVNEIYKGFEDLRELVDVGGGLGANLKTIVSKHPRIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKCVLHDWADKECVKILKNCYDALPEIGKVIAVESVLPELPEDDFVSKQSYNFDVAMFMANPGGKERTKRELEALAKEAGFAAMEVTCRAYSSWVIVFYKRA
>mrna:Maker00003318
MSEIQNQHEKEETGKQAVLLANAGILPMVLKSALELNIIDILSTATSGGAWLSPSEVAARIPTKNPDAPSLIDRMLPFLASFNVIKCSVSTSENGELEGAYGAAPICKFLSRNQEDEGGSIAPLILLHHDEVFHKSWYHLNDVILEGGIPFNRAYGMTAFEYPATDQRFNRVFNQAMSNHTTLIIKKILEAYKGFDGLNVLVDVGGGVGVALKMIVSRHPHIKGINYDLAHVLADAPSYPEVEHVGGDMFVSVPKGDAILMKWILHDWTDEHCLKLLSNCWEALPINGKVIIVESILPEAPERDVSSQIVFGQDLFMLAQNPGGKERSQKEFDALAKKSGFSGCEVMCPAYNSWVMEFRKRS
>mrna:Maker00003465
MLEHHALQLELQASVMAIVRRYRLSDVVLEGGIPFDRAHGTSEFEYTATDPRFNKLFNQGMSNCTTMVMKKMLEVYKGFDGINVLVDVGGGIGANLKMILSKHPHIKGINYDLAHVVAGASSHPGIEFVGGDMFVSVPKGDAILMKWVLHDWSDEHCLKVLKNCCQALPSNGKVILVELILPRTPEKDTSARIGFGQDLLLLAHNDGGRERTQKDFDGLAKKSGFSGCKVMCSAYDHWVMELHKKA
>mrna:Maker00016445
MEDESSESRNRARLGIIGLTNLISIPMSLQAIVRLNVADAIWQGGANSPLSASEILSCVHPSGGDADNLQRILRMLASYGVFHEHLRSDGSERRYSLTDIGKTLVTDGDGLSYAPYVLQHHQEALIQAWGLVHEAVLDPTTNPFVKANGEAAYIYYGKQPAMNSLMQKAMAGISVPFMKALLEGYDGFQGVERLVDVGGSAGDCLRMIIKKYPGIRQGINFDLPDVVARAPHIPCVSHVGGDMLKSIPEGDAIFMKWILSTWAYDECKKIMENCYKVLPAGGKLIACEPVLPENPDDSHRTRTLLENDLFIMTIYGAKGKVRTEQEFERLGLAVGFSQFRALYIDYFFTVLEFQK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University