Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Kandelia obovata
Species name
Kandelia obovata is a species of eudicot in the family Rhizophoraceae (red mangrove family).
Species info
Gene sequence info
Kandelia_obovata.HIDH.fa
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>mrna:Maker00008088
MEVARELLPFLRVYTDGSVERLQSSPYVSPSPVPDLETGVSSKDITISHDPNISVRVYLPKLTKPHQKVPILVHFHLGAFCVGSAFSFHGHRYMNSLVSEAQVLAVSVEYRLAPEHPLPAAYEDCWDALKWVASHSVEKDLADGHKEPWIFDHGDFGRVFIGGDSAGGNIVHNLAMRAGAESLDGKVKILGAFLGHPYFWGSKPVGNEPIENHENALGWRVWDFVYPSAPGGIDNPMVNPAGPGAASLAGLGCSKLLVCIAGKDELRDRGIMYYNLVKESGWGGEVDLFEVEGEDHAFHVINSETENAKNMIKCLASFLNNN
>mrna:Maker00011839
MNRTKEVSQDIISFVRVYKDGTIERLAGTEIAPPGLDAETDVLSVDAVVVPETGVRARLYRPNSAKASEKLPLVIYLHGGGFFISSAADPKYHHSLNKLVAEANVLLVSVDYRLAPEVPLPAAYEDSWAALEWVAAHAKAGGPAAAQEATWLDDYADYGRIYLVGDSCGANMTHHFALRLKESRLGRELKVQGIAMLCPYFWGKNPIGVEATDHLRKSMVDSWWNFVCTSDKGCDDPLINPFADGSPGLEDLACSRVIAIVAEKDILRDRGQVYYEKLVESQWQGTAEFVEIKGEDHIFHIFDPNCENARSLFKRLASFINQA
>mrna:Maker00018734
MVGEKKVVREVSGWLRVYDDGSVDRTWTGPPEVKFLADPVPSHEEFISGVATRDVTVDSLSGLRVRIYLPEPHQDQTKLPIILHFHGGGFCISQADWCMYYNTYTRLAKAARAICVSVYLRLAPEHRLPAACNDGFSALLWLRSLARGESHEQWLNCHGDFNRVFLIGDSSGGNLVHEVAARAGQVDLTPLRVAGCIPIHPGFVRSERSRSELENPQSPFLTLDMVDKFMGLSLPVGCTKDHPITCPMGPGAPPLAGLNFPPCLLCVAEDDLIVDTEMEYYEAMKKANKVVQLLTSPGMVHSFYLNKLAVDMDPRTAAQTTGLIEGITEFIKKH
>mrna:Maker00012720
MDSTSKEIDYELLSLVRVYKDGSVDRLSGSSAVAPPSLEDPVTGVSSKDVNISQDPPISARLYLPKLTDPQKKIPILVYFHGGGFCIESAFSSVETSYIKSLVSQAEVVAVSVDYRLAPEHPLPIAFEDSWAALQWVASHSVGNGKDKDPWILNHGDFGRVFIGGDSAGANIGHNIGMRAGSESLPGGVRLLGAFLTHPYFWGSDQIGSESTSDPESHLPYKIWVTFYPSAVGGIDNPMVNPLAPGAPSLAGFGCTRLLLEVAERDHLLLRDRGVLYYNAIKESGWKGDVELIEVKGEDHAFHILEPEKESSKVLIKRLASFLRRQ
>mrna:Maker00017859
MHPPPYEVDECRGVLRVYSDGSVWRSSEPSFKVSVQDDGSVEWKDVVFDPNHNLLLRLYKPAGYSSSASKLPIFYYIHGGGFCIGSCTWPNFHNYCLKLSLELQAVVVSPDYRLAPENRLPAAIDDGFASVKWLQAQAFSQEPDPWLTDVADFGKVFISGDSAGGNIAHNLAVRLRAGSPELTPVQVRGYVLLEPFFGGTVRTKSEAEGPKEAFLNLEMIDRFWRLSIPTGDTTDHPLVNPFGPTSQNLELVDLDPILVVGAGCDLLKDRALDYAERLKKWGKKIDYVEVEGQQHGFFTLNPSSDAAKKPMPVIKSFIAQNCT
>mrna:Maker00004799
MYGRDRPAPVAYKIDSNTVLCSSSFLRLHSMRKRTMAAITLCSRSSLETGKNSHQQEAVKEEVEGLIRVYNDGHVERPQIVPCVTTALAPELGVTSQDIVIDKATNIWARLYVPLTYQGNNHRLPLIVYFHGGGFCVGSVAWCCYHEFLASLAATAGCLIMSVNYRLAPENPLPAAYEDGITALIWLKQQAMNNFPSELWSRQCNFSNIYLAGDSAGANIAYNVVLMLASLSLKPLILKGAILIQPFFGGELRTNSEKYLAQSPQSALSLPASDTYWRLALPAGASRDHPWCNPLSKGSVKMEELKLCIPNFMVCIAEMDILKDRDFEFVAALARAGVRVQHVVHRNMGHAFQVLSRSQLSQNRTLEMMSQVKVFIAR
>mrna:Maker00005511
MDANQSEVVQDFYPFVRIYKNGRIERFLGTEIVPPSLDDPKTSAQSKDVVYSTEANLSSRLYLPKDTTANQKLPLLVYFHGGGFVVETAFSPVYQNYLNSLVAEAKVIVVSVDYRRAPEHRLPVAYDDCWTALKWVASHFDRNGPEEWLNSHADFGSVLLAGDSAGANIAHNMAMRCGQEKIPGIDLRGIVLIHPYFWGKDPVGDEQSEGRDRHERFWRFVCPSTSGCDDPLINPVADPNFASLGCSNVLVTVAGKDMLKHRGWNYYENLKKCGWSGQIEMMEAEGEDHVFHLFNPDGQNSVAMLQKISVFLNSKACVTGGI
>mrna:Maker00006135
MDTNESEVLHDLFPWVRMYKNGQVERFLCTETVPPSLDDPKTSVQTKDVVHSTETNLSSRLHLPKDTKANQKLPLLVYFHGGAFLIESAFSVPYVYFLNSLVAEANVIVVSVDYRRAPEHRLPAAYDDCWTAVKWVASHFDRNGPEEWLNSHADLGRVFFAGDSAGANIAHNMAMRYGQEKIPGIDLKGIVLIHPYFWGKDPVGDEPSEGRDAYERLWRFVYPATSGCDDPLINPVADPNFASLGCSKVLVTVAAKDVFKHRGCYYSENLKKCGWSGEVELMEAEGEDHVFHMFHPTAPKSVAMLQKISAFLNS
>mrna:Maker00003698
METIAAKQEIAFELPGTLRVYKDGRVERLRETDIVPASSDPFTCVSSKDVTSLPESNVSARLYLPKLGNPTQKFPLLVYFHGSAFCVSSPFTNKYHSYVAKLVSEANVVAVSVDYRKAPEHPIPAAYEDSWETLQWVVSHRNGDGPESWLNDHADFERVFLVGESAGANIVHNLAMAAGNSEFGLLGAALVHPYFWGSDPIGSEAADPDGKALADRLWPFTCPSNPDNDDPRVNPVAMGAPSLTGLGCKRVLVCVAEKDVLRDRGWLYYKALGGSGWMGVVEIAETKAEDHCFHLYDLESEKANVLVKRIAAFLNRDINN
>mrna:Maker00017328
MPEVAHDYSPFLRIYTDGYIERLMGTDIVPPSLEDPETNVQCKDVVYSPEDNLSSRLYLPKNANPNKKLPLLIYFHGGGFCIQTPFSATYNNYVNTLVGEANIVAVSVHYRRPPEDPLPIAYDDSWTALKWVASHVSGDGPEEWLNDHADLSKVFLAGDSAGGNIAHQISMRIVQEKLTAGVNVSGIVLIHPYFWGVEPIGKEAEKLEKGKSAAAIWYAACPTTSGCDDPLINPLADPKLASLGCSRVLVIVAEKDLLRDRGWAYYKELKKNGWGGVVEIMENRGEDHVFHLQNPTCENAVAMLKKISSFINEDQA
MEVARELLPFLRVYTDGSVERLQSSPYVSPSPVPDLETGVSSKDITISHDPNISVRVYLPKLTKPHQKVPILVHFHLGAFCVGSAFSFHGHRYMNSLVSEAQVLAVSVEYRLAPEHPLPAAYEDCWDALKWVASHSVEKDLADGHKEPWIFDHGDFGRVFIGGDSAGGNIVHNLAMRAGAESLDGKVKILGAFLGHPYFWGSKPVGNEPIENHENALGWRVWDFVYPSAPGGIDNPMVNPAGPGAASLAGLGCSKLLVCIAGKDELRDRGIMYYNLVKESGWGGEVDLFEVEGEDHAFHVINSETENAKNMIKCLASFLNNN
>mrna:Maker00011839
MNRTKEVSQDIISFVRVYKDGTIERLAGTEIAPPGLDAETDVLSVDAVVVPETGVRARLYRPNSAKASEKLPLVIYLHGGGFFISSAADPKYHHSLNKLVAEANVLLVSVDYRLAPEVPLPAAYEDSWAALEWVAAHAKAGGPAAAQEATWLDDYADYGRIYLVGDSCGANMTHHFALRLKESRLGRELKVQGIAMLCPYFWGKNPIGVEATDHLRKSMVDSWWNFVCTSDKGCDDPLINPFADGSPGLEDLACSRVIAIVAEKDILRDRGQVYYEKLVESQWQGTAEFVEIKGEDHIFHIFDPNCENARSLFKRLASFINQA
>mrna:Maker00018734
MVGEKKVVREVSGWLRVYDDGSVDRTWTGPPEVKFLADPVPSHEEFISGVATRDVTVDSLSGLRVRIYLPEPHQDQTKLPIILHFHGGGFCISQADWCMYYNTYTRLAKAARAICVSVYLRLAPEHRLPAACNDGFSALLWLRSLARGESHEQWLNCHGDFNRVFLIGDSSGGNLVHEVAARAGQVDLTPLRVAGCIPIHPGFVRSERSRSELENPQSPFLTLDMVDKFMGLSLPVGCTKDHPITCPMGPGAPPLAGLNFPPCLLCVAEDDLIVDTEMEYYEAMKKANKVVQLLTSPGMVHSFYLNKLAVDMDPRTAAQTTGLIEGITEFIKKH
>mrna:Maker00012720
MDSTSKEIDYELLSLVRVYKDGSVDRLSGSSAVAPPSLEDPVTGVSSKDVNISQDPPISARLYLPKLTDPQKKIPILVYFHGGGFCIESAFSSVETSYIKSLVSQAEVVAVSVDYRLAPEHPLPIAFEDSWAALQWVASHSVGNGKDKDPWILNHGDFGRVFIGGDSAGANIGHNIGMRAGSESLPGGVRLLGAFLTHPYFWGSDQIGSESTSDPESHLPYKIWVTFYPSAVGGIDNPMVNPLAPGAPSLAGFGCTRLLLEVAERDHLLLRDRGVLYYNAIKESGWKGDVELIEVKGEDHAFHILEPEKESSKVLIKRLASFLRRQ
>mrna:Maker00017859
MHPPPYEVDECRGVLRVYSDGSVWRSSEPSFKVSVQDDGSVEWKDVVFDPNHNLLLRLYKPAGYSSSASKLPIFYYIHGGGFCIGSCTWPNFHNYCLKLSLELQAVVVSPDYRLAPENRLPAAIDDGFASVKWLQAQAFSQEPDPWLTDVADFGKVFISGDSAGGNIAHNLAVRLRAGSPELTPVQVRGYVLLEPFFGGTVRTKSEAEGPKEAFLNLEMIDRFWRLSIPTGDTTDHPLVNPFGPTSQNLELVDLDPILVVGAGCDLLKDRALDYAERLKKWGKKIDYVEVEGQQHGFFTLNPSSDAAKKPMPVIKSFIAQNCT
>mrna:Maker00004799
MYGRDRPAPVAYKIDSNTVLCSSSFLRLHSMRKRTMAAITLCSRSSLETGKNSHQQEAVKEEVEGLIRVYNDGHVERPQIVPCVTTALAPELGVTSQDIVIDKATNIWARLYVPLTYQGNNHRLPLIVYFHGGGFCVGSVAWCCYHEFLASLAATAGCLIMSVNYRLAPENPLPAAYEDGITALIWLKQQAMNNFPSELWSRQCNFSNIYLAGDSAGANIAYNVVLMLASLSLKPLILKGAILIQPFFGGELRTNSEKYLAQSPQSALSLPASDTYWRLALPAGASRDHPWCNPLSKGSVKMEELKLCIPNFMVCIAEMDILKDRDFEFVAALARAGVRVQHVVHRNMGHAFQVLSRSQLSQNRTLEMMSQVKVFIAR
>mrna:Maker00005511
MDANQSEVVQDFYPFVRIYKNGRIERFLGTEIVPPSLDDPKTSAQSKDVVYSTEANLSSRLYLPKDTTANQKLPLLVYFHGGGFVVETAFSPVYQNYLNSLVAEAKVIVVSVDYRRAPEHRLPVAYDDCWTALKWVASHFDRNGPEEWLNSHADFGSVLLAGDSAGANIAHNMAMRCGQEKIPGIDLRGIVLIHPYFWGKDPVGDEQSEGRDRHERFWRFVCPSTSGCDDPLINPVADPNFASLGCSNVLVTVAGKDMLKHRGWNYYENLKKCGWSGQIEMMEAEGEDHVFHLFNPDGQNSVAMLQKISVFLNSKACVTGGI
>mrna:Maker00006135
MDTNESEVLHDLFPWVRMYKNGQVERFLCTETVPPSLDDPKTSVQTKDVVHSTETNLSSRLHLPKDTKANQKLPLLVYFHGGAFLIESAFSVPYVYFLNSLVAEANVIVVSVDYRRAPEHRLPAAYDDCWTAVKWVASHFDRNGPEEWLNSHADLGRVFFAGDSAGANIAHNMAMRYGQEKIPGIDLKGIVLIHPYFWGKDPVGDEPSEGRDAYERLWRFVYPATSGCDDPLINPVADPNFASLGCSKVLVTVAAKDVFKHRGCYYSENLKKCGWSGEVELMEAEGEDHVFHMFHPTAPKSVAMLQKISAFLNS
>mrna:Maker00003698
METIAAKQEIAFELPGTLRVYKDGRVERLRETDIVPASSDPFTCVSSKDVTSLPESNVSARLYLPKLGNPTQKFPLLVYFHGSAFCVSSPFTNKYHSYVAKLVSEANVVAVSVDYRKAPEHPIPAAYEDSWETLQWVVSHRNGDGPESWLNDHADFERVFLVGESAGANIVHNLAMAAGNSEFGLLGAALVHPYFWGSDPIGSEAADPDGKALADRLWPFTCPSNPDNDDPRVNPVAMGAPSLTGLGCKRVLVCVAEKDVLRDRGWLYYKALGGSGWMGVVEIAETKAEDHCFHLYDLESEKANVLVKRIAAFLNRDINN
>mrna:Maker00017328
MPEVAHDYSPFLRIYTDGYIERLMGTDIVPPSLEDPETNVQCKDVVYSPEDNLSSRLYLPKNANPNKKLPLLIYFHGGGFCIQTPFSATYNNYVNTLVGEANIVAVSVHYRRPPEDPLPIAYDDSWTALKWVASHVSGDGPEEWLNDHADLSKVFLAGDSAGGNIAHQISMRIVQEKLTAGVNVSGIVLIHPYFWGVEPIGKEAEKLEKGKSAAAIWYAACPTTSGCDDPLINPLADPKLASLGCSRVLVIVAEKDLLRDRGWAYYKELKKNGWGGVVEIMENRGEDHVFHLQNPTCENAVAMLKKISSFINEDQA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University