Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Amborella trichopoda
Species name
Amborella trichopoda is a species of flowering plant in the family Amborellaceae.
Species info
Gene sequence info
Amborella_trichopoda.CHS.fa
Download
>XP_006837297.1
MANGQNGSDNGFIGEQKEATILAVGKAFPEQVIPQECLVEAYFRNTNCQDPVIREKLERLCKNTTVKTRYTVISKEILDKYPELTTEGSPTITQRLDIANHAVLEMALQASLSCISDWGKPVSQITHLVYVSSSEIRFPGGDLYLAANLGLKTDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTAETTILGYRPPNLARPYDLVGAALFGDGAAAVIVGSGPFSEGEKPFMELHNAVQEFLPGTQGIIEGRLTEEGINFKLGRDLPQKIEGHIDIFCKNLMKNANLTEFNDLFWAVHPGGPAILNKLESNLRLNPEKLKCSRKALMDYGNVSSNTIFYVLDYMREEAKEDGGEEWGLVLAFGPGITFEGILVRRLY
>XP_006837977.1
MVSVEELRKAQRADGPATVLAIGTANPPNVVEQAHFPDFYFNITNLQDLYLKDKFSRICAKSGIKKRHLFLTEERLSANPSLCSYMAPSLDARQELVLEEIPRLGKEAALCAIKEWGQPVSGITHLVFCTTSCIDMPGADLRLANLLNLSPCVNRVMLYLQGCFAGATALRIAKDLAENNHNARVLVVCSEMIPIFFRGVHASHLESLVGPALFGDGAAAVIIGSDPLTTERALYQLAWAGQSIVPDSTHALAGHLREVGLTFTLSKELPMLLTKSVKDCLSHALEPLGITDWNSIFYAAHPGGPLVMDKMENELGLKPEKLRATRHVLEEYGNMSSPSVLFVLDEMRKWSAEQGAATTGEGLEWGVLFGFGPGLTIETVVIRSMPT
>XP_011627026.1
MVNVEAIRKAQRAEGPATIMAIGTATPPNSVDQSTYPDYYFRITKSEHKTQLKEKFKRLCEKSMIKKRYMYLTEEILKENPTVCEYMAPSLDARQDMVVVEVPKLAKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRVMMYQMGCYAGGTVLRVAKDLAENNRGARVLAVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALIVGSDPLPVERPIFELIWTGQTILPDSNGAIDGHLREVGLTFHLLKDVPGIISKNIDKALVEAFEPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKLRATRHVLSEFGNMSSACVLFILDEMRRKSAQDGCKTTGEGLEWGVLFGFGPGLTVETVALRGIATA
>XP_020529151.1
MIKKRYMYLTEEILKENPTVCEYMAPSLDARQDMVVVEVPKLAKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRVMMYQMGCYAGGTVLRVAKDLAENNRGARVLAVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALIVGSDPLPVERPIFELIWTGQTILPDSNGAIDGHLREVGLTFHLLKDVPGIISKNIDKALVEAFEPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKLRATRHVLSEFGNMSSACVLFILDEMRRKSAQDGCKTTGEGLEWGVLFGFGPGLTVETVALRGIATA
>XP_020532038.1
MVNVEEHRKAQRADGAATVLAIGTANPPPSPQCDILICFLSSKLLRFTLWILGLDPNEVKPGAVASVDSIPLGLLRSTPATFDASGFSGADIYPLYGSNNACSGPGIDLHLKLLNLSPFVNRVMIYMQGCFAGGTTLRSAKDLAENNCGACVLIVCPEMMSMYFHGPIRMDPESLVVPALFGDGAATVVIGADPMSTERGLNQLFRACQSIVPNSMHALKGPIHEAGITYWNTLFYVVHPGGPRILDKMEDDLKLKPEKLRAACHVLREYENMWSATMFVVLDEIQKSS
MANGQNGSDNGFIGEQKEATILAVGKAFPEQVIPQECLVEAYFRNTNCQDPVIREKLERLCKNTTVKTRYTVISKEILDKYPELTTEGSPTITQRLDIANHAVLEMALQASLSCISDWGKPVSQITHLVYVSSSEIRFPGGDLYLAANLGLKTDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTAETTILGYRPPNLARPYDLVGAALFGDGAAAVIVGSGPFSEGEKPFMELHNAVQEFLPGTQGIIEGRLTEEGINFKLGRDLPQKIEGHIDIFCKNLMKNANLTEFNDLFWAVHPGGPAILNKLESNLRLNPEKLKCSRKALMDYGNVSSNTIFYVLDYMREEAKEDGGEEWGLVLAFGPGITFEGILVRRLY
>XP_006837977.1
MVSVEELRKAQRADGPATVLAIGTANPPNVVEQAHFPDFYFNITNLQDLYLKDKFSRICAKSGIKKRHLFLTEERLSANPSLCSYMAPSLDARQELVLEEIPRLGKEAALCAIKEWGQPVSGITHLVFCTTSCIDMPGADLRLANLLNLSPCVNRVMLYLQGCFAGATALRIAKDLAENNHNARVLVVCSEMIPIFFRGVHASHLESLVGPALFGDGAAAVIIGSDPLTTERALYQLAWAGQSIVPDSTHALAGHLREVGLTFTLSKELPMLLTKSVKDCLSHALEPLGITDWNSIFYAAHPGGPLVMDKMENELGLKPEKLRATRHVLEEYGNMSSPSVLFVLDEMRKWSAEQGAATTGEGLEWGVLFGFGPGLTIETVVIRSMPT
>XP_011627026.1
MVNVEAIRKAQRAEGPATIMAIGTATPPNSVDQSTYPDYYFRITKSEHKTQLKEKFKRLCEKSMIKKRYMYLTEEILKENPTVCEYMAPSLDARQDMVVVEVPKLAKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRVMMYQMGCYAGGTVLRVAKDLAENNRGARVLAVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALIVGSDPLPVERPIFELIWTGQTILPDSNGAIDGHLREVGLTFHLLKDVPGIISKNIDKALVEAFEPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKLRATRHVLSEFGNMSSACVLFILDEMRRKSAQDGCKTTGEGLEWGVLFGFGPGLTVETVALRGIATA
>XP_020529151.1
MIKKRYMYLTEEILKENPTVCEYMAPSLDARQDMVVVEVPKLAKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRVMMYQMGCYAGGTVLRVAKDLAENNRGARVLAVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALIVGSDPLPVERPIFELIWTGQTILPDSNGAIDGHLREVGLTFHLLKDVPGIISKNIDKALVEAFEPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKLRATRHVLSEFGNMSSACVLFILDEMRRKSAQDGCKTTGEGLEWGVLFGFGPGLTVETVALRGIATA
>XP_020532038.1
MVNVEEHRKAQRADGAATVLAIGTANPPPSPQCDILICFLSSKLLRFTLWILGLDPNEVKPGAVASVDSIPLGLLRSTPATFDASGFSGADIYPLYGSNNACSGPGIDLHLKLLNLSPFVNRVMIYMQGCFAGGTTLRSAKDLAENNCGACVLIVCPEMMSMYFHGPIRMDPESLVVPALFGDGAATVVIGADPMSTERGLNQLFRACQSIVPNSMHALKGPIHEAGITYWNTLFYVVHPGGPRILDKMEDDLKLKPEKLRAACHVLREYENMWSATMFVVLDEIQKSS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University