Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Kalanchoe fedtschenkoi
Species name
South american air plant (Kalanchoe fedtschenkoi) is a species of eudicot in the family Crassulaceae (stonecrop family).
Species info
Gene sequence info
Kalanchoe_fedtschenkoi.HIDH.fa
Download
>Kaladp0008s0320.1.v1.1
MVQQKTKVVQEVSGWLRVYEGGSVDRTWTGPPQVKFMMEPVQAHTHFVDGVAVRDVTSNSGVRVRIYLPEKQPGDGQKLPVLLHLHGGGFCISQPDWYMYYQFYTRLARTARVICVSAYLRLAPEHPLPAACHDGYAALRWLGSEGHADPCLQPHADFNRVFLIGDSSGGNLVHEVAARAGHDTGLTRITLAGAIPIHPGFVRSTRSKSEMEQPESPFLTLDMVDKFLALALPAGSNKDHPITCPMGPVAPAMEGLKMPPMLLCVADMDLIKDSEMEYYEAMKEAGKDVELLMSYKVGHSFYLNKIAVDSDPQTSAQTADLISGIARFINKH
>Kaladp0018s0094.1.v1.1
MAMSEKVWKLVYPGMPGLDDRVINPLTYLERARKAARAAVYGEVMKRCGKEGLKVDVLWSEGMDHVFHLIDPDCEEAKQMMKKVVAFIKLTE
>Kaladp0018s0096.1.v1.1
MPFQFPVPTPADPEDIALDIYPLLRIFKDGKIERFLGTASVPAGTDPATGVQSKDVILSPEDGVGVRLYLPKDASPEKKLPLVVYFHGGGFCVETAWSPVYHTYLNALTSEANAVVASVNYRLAPEHPLPAAFEDSWRILKWAASHSGSGLIPEPAEPWLSEYVDFNKVFLAGDSAGGNISHHMAVKAGEEGLPGAKLDGIIPTHPFFSGVEPVGNERDLPPQVLAVHEKIWRLVHPGMEDLDDPVINPVKDVSKAGKVGCGRVLVCVAEKDALMARGVEYGEVMRRCRKEPALEVEVFKSVGMQHVFHLFDPECEEAAELMKKVVQFINGASTNV
>Kaladp0018s0095.1.v1.1
MVKFRISFTLCVKLLSLDLSPEAMAFKFPIPTPADHPEDIELDIYPLLRIFKDGKIERFLGTATVSAGTEPATGVQSKDVILSPEDEVGVRLYLPKDARREKKLPLVVYFHGGAFCANAVVASVNYRLAPEHPLPAAFEDSWRILKWASASHSEGSSLSPEPVAEPSLSEYVDFNKVFLAGDDAGGNIAHNMAVRAGKEGLPGAKLHGIILSHPYFSGVEPVENERDLPPESLAMHEKIWKLVHPGMLAVWDYPVISWVKEDLSKAREEEEEVDQYGRLLASTAWINAMQDRRVGYGEVMRRRGKVPVMEIEAFRSVGMEHVFHLFDPDCEEAKEMMKMVVEFINNSGQSADL
>Kaladp0018s0091.1.v1.1
MASPSETPSKDELSLDGSPFLRVHKDGRVERLIGTAIVPAGLDPATGVESRDVSITEDGSVRARLYVPQAADPGKKIPLLVYFHGGGFCIESAWSPTYHNYLNALVSEATIVAVSVNYRLAPEHHLPTAYDDSWAAIKWIAAPETDPWLVQFADLNRVYISGDSAGGNIAHHMCIRLGTEPLPGVTLAGAILVDPFFWGEERIGGESARDKAIPEFLNNLWKLAIPSLKSYDHPWINPGIEPERLRMIACERVLVCVAGADLYMCDRGEAYCETLRRSGWGGSVEMFRSEGVGHVFHLEDPASELAVKLMKKVVEFINEGSA
>Kaladp0018s0092.1.v1.1
MAASSETSSLDGSPILRIHEDGRVERLIGTAIVPAGLDLATGVESRDVSITKDGSVGARLYVPKAADPGKKIPLLVYFHGGGFCLESAWSPTYHSYLNALVSEANIVTVSVNYRLTPEHPLPTAYDDSWAAIKWIAAPETDPWLVQFADLNRVFFSGDSAGGNIAHHMSARLGTEPLPGVTLAGAILTDPFFWGEEWIRRESARDKAISELLSSMWKLAIPGLKSYDHPWMDPGLEPERLGMMACERVLVCAAGADFYMCERGEAYCEALRMSGWGGSVEMLRSEGVGHVFHLEDRASEVAVRLMKKVVDFINEGSA
>Kaladp0018s0098.1.v1.1
MFNSPSAIPPPQSVDEDVLHDFHPFFKVYKDGRVERYAFHNQPVRPPGFDPETGIETKDIVLDSDTGLTVRLFTPNLENLDHKVPLIIHIHGGGFCVGSALDAITHNFVASLLSQVQAVVISVEYRLAPEHPLPTAYEDSWEALKWVGSHAAGSGPEPVLNRSVDLDKVFLLGESAGANIAHNLVTRAGTEGLPGLKIAGMVAVHPFFVGDEEDRHYKFLCPTSSGCRDDPRLCPGADPGLARMVTGRVLVCLAEKDHLRGRGLEYYETLRKSGWVGSVELFESEGRDHCFHMFSKDEKAQELIKKFAEFVKRE
>Kaladp0022s0084.1.v1.1
MASSHSAEDADVTYHCKFFQIHRNGVVRVHRPMRDRPDPPPSDPRYRIRFRDVVISQPDSVTARIFLPEPEPGSDSKLPVILYIHGGGFCMLSPYAAQYHRYCTQLAAEAGALVVSVDYGLFPDRPIPACYDDSWAALKWVAAHSSGSGPDPWLTRYADFNNVFIAGDSAGGNITHTLALRVGLTGLHGAKVVGAVLVHPFFGGTEDDAIWLKMCPTNEGVDDPRMNPSEEDLAALGCEKVLIFVAEKDHLCEPGKRYYEKLMRSGWRGKVEMVENLGMQHCFHIVQEVEDEHAAEMLRKVAAFVRGE
>Kaladp0024s0193.1.v1.1
MASLSIHSIQSLQASKSEHQQHTNSSSVVVEEVEGLIRVYKDGRVERHQIVPCVGASHSLPESETNAVTSMDVVVDRGTSIWARVYVPKCQGVVKLGGGHTKLPVLVYFHGGGFCVGSASWVCYHEFLAKLAAKANCLIISVNYRLAPENPLPAAYEDGLKTLMWVKQQAASSVGVSSNELWVRSLNLSKMFLAGDSAGANIAYHVSKMLSPNMLRPLCIKGTILLQPFFGGELRTNSEKYLTQSARSALTLEASDAYWRMALPRGANRDHPWCNPVAHKLSIKSEDMQVATLVCIAEMDIMRDRSMEYCAALGAAGHKVEFAVSKGVGHAFQILNKSQHAQNRTLEMIKQVKNFISR
>Kaladp0040s0734.1.v1.1
MESDSKPSEAQLLHDFVCFKVFADGHSSDTESSRDDEGEDIVFTAPSYFQIRKDGRVERFRGNETIPPGTDDRTGVRSKDVVISPDNKVGARLYIPKEADFGEKLPLLVHFHGGGFCLFSAWHPWYYLYLSRLASQAKVVIVSVDYRLVPEHPLPAAYDDCWAAIKWAAAHSTGDGPEPWLNEFADYGNVFFAGESAGGNIAHQMALRAGTNPLPGIKLKGVIIDVPFFFGAESIGKESGLPETEREKGEKIWLKAIPDLKTLDHPWINPLADLEKMSKMGCKRVLVHVAEVDSLRDRGVAYYEALRGCGWSGRAELFESRGVGHAFQLFNPKCQQVEELLKKYVEFINEGVRDA
>Kaladp0048s0270.1.v1.1
MAWSPQVEANDRIIFLPCFSQTIGRIVVEFCHAYSESFKARFEGCKLKHYKWTTLTAASIELRLDIVLAPDTWLTVRLFTPDSDHNLPLIIHIHGGGFCVSGQPSIPLPTTSSPPYSSLGFKPLCYPSSTVRARALSFYLLMGEALKWYCWIWRRQYA
>Kaladp0060s0248.1.v1.1
MVDDKKVAVEVSGWLRVYEGGSVDRTWTGPPEYKFLTEPAPPHNHFIDGVAIRDVTSNSGDVRVRIYLPEKQPDDSEKLPILLHLHGGGFCISVADWYMHYQFYARLARTARVICVSAFLRLAPEHPLPAACDDGYEALRWLASSEGRAEPWLQSHADFNRVFLIGDSSGANLVHELAARAGRDDSLTQITLAGAIPIHPGFLYSTRSKSEMEQPESPFLTLDMVDQFLAFALPAGSNKDHPITCPMGPAAPPLESLKLPPMLLCVTDLDLIKDTQMEYYEAMKKAGKDVELLMNYKVGHSFYFNKIAVDSDPDTAAQTADLISGIASFINKH
>Kaladp0061s0041.1.v1.1
MVKNQTAITLSLTNHLISTAARDSNFIFSPLSIHSALALLIVGVGRGILVKLEWVAAHVKNGQRADLWPKQHVDLSKLFIAGDSVGGNITYNPLVRVGKCVLPDGVRLIGSVLVHPYLFGSGDATDQMWMYICPNNKGIDDPGIKPDLNDLKLIPGNRMLVLETEKDEYHLRDRGFAFVDQLKKSSWRREVDIYEIPDEVHSFHLNGDMSRPVARDFIKCEDIIFTVTGYFQILKDGRVVRSLGIETVPPGTDDRTSVRSKDIVIHNITKSGLSSTPRKRPISERSFLC
>Kaladp0088s0064.1.v1.1
MLKQHADLSKLFVVGDNVGGNITYNLLVRAGKCGLLDGVSLIGSVLVNSYLSSSEDATNQMWMYICPDNKGVDDPKIKPDLNDLKLISGNRMLLLKVKKDEYQLRDRELAFAVSSRKVAGVERSTPMKPPARSLRARTHNPRGTMKARTLSSLFSGTFKSVKMVRLRDFGV
>Kaladp0092s0226.1.v1.1
MGSNSTEKEVAHDVFPYLRQYKDGSVERLNGTATCPPNTHPHVLSKDVIIDSRTGISARLYLPKNINKDERKLPLFVYFHGGAFLIASPAEPLYDASLNTIVAQANVVAVSVDYRLAPEHPLPTAYDDCWSALQWISAHASSGSGGGSEAWLTDHVDFSRVYLAGDSAGANIAHHVSFRAADADPEVVVRPAGIVMIHPYFWSKDPTESELSDPVRKGMVDKWWIYACPSEKGCDDPLINPYADGSPSLAGLGCERLMVCVAEKDILCDRGRVYYESVVRSGWRGRAELFVSEGEDHVFHIFNPQCQKAMELIKSVAEFVNSRD
>Kaladp0095s0455.1.v1.1
MSIVAEAPGWLQVFSDGTVKRFAPEIAPPSADPAAGFKSRDVVIDQSKRITGRVFVPADYEPGADAKLPVVVYFHGGGFCIGSTTWLGYHVFLGQLSAAAACVVLSVDYRLAPEHKLPTAYEDCHRALEWLWEERDRSDNWLDRADLSHVFLAGDSAGGNIVHNVAVGNILCKSFTPKFDDHPLRIKFLGNGSLSFSPKGLILIHPYFGSERRTPKEAEADSSEEVAMNDMFWKLSLPEGTDRDYPGSNYEKLEVGAGAWRRDFPATVVFVAEVDFLKERGVMYAEFLKREGVVDVELAETKNESHVFHVFRPDSEATRVLTQQIVEFMSRRR
MVQQKTKVVQEVSGWLRVYEGGSVDRTWTGPPQVKFMMEPVQAHTHFVDGVAVRDVTSNSGVRVRIYLPEKQPGDGQKLPVLLHLHGGGFCISQPDWYMYYQFYTRLARTARVICVSAYLRLAPEHPLPAACHDGYAALRWLGSEGHADPCLQPHADFNRVFLIGDSSGGNLVHEVAARAGHDTGLTRITLAGAIPIHPGFVRSTRSKSEMEQPESPFLTLDMVDKFLALALPAGSNKDHPITCPMGPVAPAMEGLKMPPMLLCVADMDLIKDSEMEYYEAMKEAGKDVELLMSYKVGHSFYLNKIAVDSDPQTSAQTADLISGIARFINKH
>Kaladp0018s0094.1.v1.1
MAMSEKVWKLVYPGMPGLDDRVINPLTYLERARKAARAAVYGEVMKRCGKEGLKVDVLWSEGMDHVFHLIDPDCEEAKQMMKKVVAFIKLTE
>Kaladp0018s0096.1.v1.1
MPFQFPVPTPADPEDIALDIYPLLRIFKDGKIERFLGTASVPAGTDPATGVQSKDVILSPEDGVGVRLYLPKDASPEKKLPLVVYFHGGGFCVETAWSPVYHTYLNALTSEANAVVASVNYRLAPEHPLPAAFEDSWRILKWAASHSGSGLIPEPAEPWLSEYVDFNKVFLAGDSAGGNISHHMAVKAGEEGLPGAKLDGIIPTHPFFSGVEPVGNERDLPPQVLAVHEKIWRLVHPGMEDLDDPVINPVKDVSKAGKVGCGRVLVCVAEKDALMARGVEYGEVMRRCRKEPALEVEVFKSVGMQHVFHLFDPECEEAAELMKKVVQFINGASTNV
>Kaladp0018s0095.1.v1.1
MVKFRISFTLCVKLLSLDLSPEAMAFKFPIPTPADHPEDIELDIYPLLRIFKDGKIERFLGTATVSAGTEPATGVQSKDVILSPEDEVGVRLYLPKDARREKKLPLVVYFHGGAFCANAVVASVNYRLAPEHPLPAAFEDSWRILKWASASHSEGSSLSPEPVAEPSLSEYVDFNKVFLAGDDAGGNIAHNMAVRAGKEGLPGAKLHGIILSHPYFSGVEPVENERDLPPESLAMHEKIWKLVHPGMLAVWDYPVISWVKEDLSKAREEEEEVDQYGRLLASTAWINAMQDRRVGYGEVMRRRGKVPVMEIEAFRSVGMEHVFHLFDPDCEEAKEMMKMVVEFINNSGQSADL
>Kaladp0018s0091.1.v1.1
MASPSETPSKDELSLDGSPFLRVHKDGRVERLIGTAIVPAGLDPATGVESRDVSITEDGSVRARLYVPQAADPGKKIPLLVYFHGGGFCIESAWSPTYHNYLNALVSEATIVAVSVNYRLAPEHHLPTAYDDSWAAIKWIAAPETDPWLVQFADLNRVYISGDSAGGNIAHHMCIRLGTEPLPGVTLAGAILVDPFFWGEERIGGESARDKAIPEFLNNLWKLAIPSLKSYDHPWINPGIEPERLRMIACERVLVCVAGADLYMCDRGEAYCETLRRSGWGGSVEMFRSEGVGHVFHLEDPASELAVKLMKKVVEFINEGSA
>Kaladp0018s0092.1.v1.1
MAASSETSSLDGSPILRIHEDGRVERLIGTAIVPAGLDLATGVESRDVSITKDGSVGARLYVPKAADPGKKIPLLVYFHGGGFCLESAWSPTYHSYLNALVSEANIVTVSVNYRLTPEHPLPTAYDDSWAAIKWIAAPETDPWLVQFADLNRVFFSGDSAGGNIAHHMSARLGTEPLPGVTLAGAILTDPFFWGEEWIRRESARDKAISELLSSMWKLAIPGLKSYDHPWMDPGLEPERLGMMACERVLVCAAGADFYMCERGEAYCEALRMSGWGGSVEMLRSEGVGHVFHLEDRASEVAVRLMKKVVDFINEGSA
>Kaladp0018s0098.1.v1.1
MFNSPSAIPPPQSVDEDVLHDFHPFFKVYKDGRVERYAFHNQPVRPPGFDPETGIETKDIVLDSDTGLTVRLFTPNLENLDHKVPLIIHIHGGGFCVGSALDAITHNFVASLLSQVQAVVISVEYRLAPEHPLPTAYEDSWEALKWVGSHAAGSGPEPVLNRSVDLDKVFLLGESAGANIAHNLVTRAGTEGLPGLKIAGMVAVHPFFVGDEEDRHYKFLCPTSSGCRDDPRLCPGADPGLARMVTGRVLVCLAEKDHLRGRGLEYYETLRKSGWVGSVELFESEGRDHCFHMFSKDEKAQELIKKFAEFVKRE
>Kaladp0022s0084.1.v1.1
MASSHSAEDADVTYHCKFFQIHRNGVVRVHRPMRDRPDPPPSDPRYRIRFRDVVISQPDSVTARIFLPEPEPGSDSKLPVILYIHGGGFCMLSPYAAQYHRYCTQLAAEAGALVVSVDYGLFPDRPIPACYDDSWAALKWVAAHSSGSGPDPWLTRYADFNNVFIAGDSAGGNITHTLALRVGLTGLHGAKVVGAVLVHPFFGGTEDDAIWLKMCPTNEGVDDPRMNPSEEDLAALGCEKVLIFVAEKDHLCEPGKRYYEKLMRSGWRGKVEMVENLGMQHCFHIVQEVEDEHAAEMLRKVAAFVRGE
>Kaladp0024s0193.1.v1.1
MASLSIHSIQSLQASKSEHQQHTNSSSVVVEEVEGLIRVYKDGRVERHQIVPCVGASHSLPESETNAVTSMDVVVDRGTSIWARVYVPKCQGVVKLGGGHTKLPVLVYFHGGGFCVGSASWVCYHEFLAKLAAKANCLIISVNYRLAPENPLPAAYEDGLKTLMWVKQQAASSVGVSSNELWVRSLNLSKMFLAGDSAGANIAYHVSKMLSPNMLRPLCIKGTILLQPFFGGELRTNSEKYLTQSARSALTLEASDAYWRMALPRGANRDHPWCNPVAHKLSIKSEDMQVATLVCIAEMDIMRDRSMEYCAALGAAGHKVEFAVSKGVGHAFQILNKSQHAQNRTLEMIKQVKNFISR
>Kaladp0040s0734.1.v1.1
MESDSKPSEAQLLHDFVCFKVFADGHSSDTESSRDDEGEDIVFTAPSYFQIRKDGRVERFRGNETIPPGTDDRTGVRSKDVVISPDNKVGARLYIPKEADFGEKLPLLVHFHGGGFCLFSAWHPWYYLYLSRLASQAKVVIVSVDYRLVPEHPLPAAYDDCWAAIKWAAAHSTGDGPEPWLNEFADYGNVFFAGESAGGNIAHQMALRAGTNPLPGIKLKGVIIDVPFFFGAESIGKESGLPETEREKGEKIWLKAIPDLKTLDHPWINPLADLEKMSKMGCKRVLVHVAEVDSLRDRGVAYYEALRGCGWSGRAELFESRGVGHAFQLFNPKCQQVEELLKKYVEFINEGVRDA
>Kaladp0048s0270.1.v1.1
MAWSPQVEANDRIIFLPCFSQTIGRIVVEFCHAYSESFKARFEGCKLKHYKWTTLTAASIELRLDIVLAPDTWLTVRLFTPDSDHNLPLIIHIHGGGFCVSGQPSIPLPTTSSPPYSSLGFKPLCYPSSTVRARALSFYLLMGEALKWYCWIWRRQYA
>Kaladp0060s0248.1.v1.1
MVDDKKVAVEVSGWLRVYEGGSVDRTWTGPPEYKFLTEPAPPHNHFIDGVAIRDVTSNSGDVRVRIYLPEKQPDDSEKLPILLHLHGGGFCISVADWYMHYQFYARLARTARVICVSAFLRLAPEHPLPAACDDGYEALRWLASSEGRAEPWLQSHADFNRVFLIGDSSGANLVHELAARAGRDDSLTQITLAGAIPIHPGFLYSTRSKSEMEQPESPFLTLDMVDQFLAFALPAGSNKDHPITCPMGPAAPPLESLKLPPMLLCVTDLDLIKDTQMEYYEAMKKAGKDVELLMNYKVGHSFYFNKIAVDSDPDTAAQTADLISGIASFINKH
>Kaladp0061s0041.1.v1.1
MVKNQTAITLSLTNHLISTAARDSNFIFSPLSIHSALALLIVGVGRGILVKLEWVAAHVKNGQRADLWPKQHVDLSKLFIAGDSVGGNITYNPLVRVGKCVLPDGVRLIGSVLVHPYLFGSGDATDQMWMYICPNNKGIDDPGIKPDLNDLKLIPGNRMLVLETEKDEYHLRDRGFAFVDQLKKSSWRREVDIYEIPDEVHSFHLNGDMSRPVARDFIKCEDIIFTVTGYFQILKDGRVVRSLGIETVPPGTDDRTSVRSKDIVIHNITKSGLSSTPRKRPISERSFLC
>Kaladp0088s0064.1.v1.1
MLKQHADLSKLFVVGDNVGGNITYNLLVRAGKCGLLDGVSLIGSVLVNSYLSSSEDATNQMWMYICPDNKGVDDPKIKPDLNDLKLISGNRMLLLKVKKDEYQLRDRELAFAVSSRKVAGVERSTPMKPPARSLRARTHNPRGTMKARTLSSLFSGTFKSVKMVRLRDFGV
>Kaladp0092s0226.1.v1.1
MGSNSTEKEVAHDVFPYLRQYKDGSVERLNGTATCPPNTHPHVLSKDVIIDSRTGISARLYLPKNINKDERKLPLFVYFHGGAFLIASPAEPLYDASLNTIVAQANVVAVSVDYRLAPEHPLPTAYDDCWSALQWISAHASSGSGGGSEAWLTDHVDFSRVYLAGDSAGANIAHHVSFRAADADPEVVVRPAGIVMIHPYFWSKDPTESELSDPVRKGMVDKWWIYACPSEKGCDDPLINPYADGSPSLAGLGCERLMVCVAEKDILCDRGRVYYESVVRSGWRGRAELFVSEGEDHVFHIFNPQCQKAMELIKSVAEFVNSRD
>Kaladp0095s0455.1.v1.1
MSIVAEAPGWLQVFSDGTVKRFAPEIAPPSADPAAGFKSRDVVIDQSKRITGRVFVPADYEPGADAKLPVVVYFHGGGFCIGSTTWLGYHVFLGQLSAAAACVVLSVDYRLAPEHKLPTAYEDCHRALEWLWEERDRSDNWLDRADLSHVFLAGDSAGGNIVHNVAVGNILCKSFTPKFDDHPLRIKFLGNGSLSFSPKGLILIHPYFGSERRTPKEAEADSSEEVAMNDMFWKLSLPEGTDRDYPGSNYEKLEVGAGAWRRDFPATVVFVAEVDFLKERGVMYAEFLKREGVVDVELAETKNESHVFHVFRPDSEATRVLTQQIVEFMSRRR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University