Enzyme
Isolated from the plant Gentiana triflora. Transfers the hydroxycinnamoyl group only to the C-5 glucoside of anthocyanin. Caffeoyl-CoA, but not malonyl-CoA, can substitute as an acyl donor.
5AT
Enzyme
Anthocyanin 5-aromatic acyltransferase
Enzyme name
EC:2.3.1.153
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
4-hydroxycinnamoyl-CoA:anthocyanidin 3,5-di-O-beta-D-glucoside 5-O-glucoside-6'''-O-4-hydroxycinnamoyltransferase
Sysname
4-hydroxycinnamoyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside = CoA + anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-(6-O-4-hydroxycinnamoylglucoside) [RN:R05163]
Reaction
CoA [CPD:C00010];anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-(6-O-4-hydroxycinnamoylglucoside) [CPD:C06363]
Product
Species information
Amaranthus hypochondriacus
Species name
Grain amaranth (Amaranthus hypochondriacus) is a species of eudicot in the family Amaranthaceae (amaranth family).
Species info
Gene sequence info
Amaranthus_hypochondriacus.5AT.fa
Download
>AH016353-RA.v2.1
MTCSETVTIVSKSTVVPSQPSAMDDLKLSVSDLPMLSCHYIQKGGLFTKPPFNSSTLISYLKDGLSIALTQFPPLAGRFVTDSSGYVFITCNDAGVEFIHATAKNVFIRDIISPIDTPDIVKEFFSYDRIVSYKGHFQPLMAIQVTELADGVFISCAMNHSVTDGTSFWNFFNTFAESCRGVKRITKSPDFSRDSVLISSEILKIPEGGPVVTFNEKEPLRERIFSFSRESILELKSKVNNRKFSTPASIELLGKQSNDPYKDGKMVSKIENWIRNAVSVSKPQAINETDSMAVEISSFQSLCALLWRCVTRARKLNSTKTTTFRMAVNCRHRLEPKLNPLYFGNAIQSIPTVAVVDDVLSNDLRWAAEQLNKNVKDHGNDTVRKYVAEWESNPRTFPLGNFDGAMITMGSSPRFPMYDNDFGWGRPVVVRSGWANKFDGKISAFPGREGGGSVDLEVVLAPETMAGLESDPEFMQFVSSC
>AH018760-RA.v2.1
MAKIIKVIRQNPTLVVPSKPTKTEVKQLSDIDDQQGLRSHVYAIMSFKPNKSKEHPAKVIKQALSRALVYYYPLAGRLFKSRPDGKLMVHCNGEGVMFIEADAEVTLKEIQPYILPPCPLLKDFLFDEGSNMVQGSFYFDPKQVQSIRNLFPTNIQNSSTTFDLICACILRCRTIALKPDPEETITFSMLVNFRGKKIINLPKGYYGNALVTPGVTAKAKELLRENSWAYALKLVMESKEKANEEYVKSMIDYMAINGRPKYAKNLHFMAVNLPSLEVSGLDFGWGAPLYFGVARAYEIQSVFMKVKNGKGENVRLVSMLLPIQVMLRLQHELGKIMGEPFGSLTIDSAHISKL
>AH018423-RA.v2.1
MVRANKLDVNEVTYCSLLTNNRHRLNPPLNPYYFGTCISAVTASTEVGELLEHDLGWVANLVHESVVNHTNESVHDFYKEWMKDSFVYKHATLYDVNSITFENSPRFDMYGNEFGVGKPVAVRNGGGNKSVGVVNAFPGCEGNGSVDLEICLPFDSMSVFESDQELIAALLMP
>AH023054-RA.v2.1
MTCSDSLLTSPSVTIVSKSTVVPAEPSSMADLKLSVSDLPMLSCHYIQKGGLFTRPPMNSSNLISILKNGLSIALTNFPALAGRFVTDSLGYVFITCNDAGVDFVHATAKNVYVRDILSPTDVPDIVKEFFTYDRTVSYKGHFQPLMAVQVTELADGVFISCAMNHSVTDGTSFWNFFNTYAEICRGVKKITKSPEFSRDSILISPAILTVPEGGPVVTFNEREPLRERIFSFTREAIVELKSKVNNRKFSTVHPSIELIGKQSNDPYNDGKMTSKIENWIRNAITVSKPQSLNETETMAVEISSFQSLSALLWRSVTRARKLDPSKTSTFRMAVNCRHRLEPKLDPLYFGNAIQSIPTVAVMGDLLSNDLRWAAEQLNKNVRDHGNDTVRRCVAEWESNPRTFPLGNFDGAMITMGSSPRFPMYDNDFGWGRPVAVRSGRANKFDGKISAFPGRDGGGSVDLEVVLAPETMAGLESDPEFMQFVSVVR
>AH000084-RA.v2.1
MNTKIISKDIIKPYHPTPKNLRLLQASLFDHVNSPTLMPLIFFFSYPKTPTTTNITPTNKTLIKLKESLPITLSLFYPLAGRVRDVDHIDCNDEGVPYIETEVDQPLENIIHKVDVCHLDKLLPSYGHNKQGFTKLLLAIQINVFMCGGLAISVKMSHAISDAFSSFMFVNTWASIASSNKQHKITRFSPCFEISKAFPPLLSSNTKKYHIHSDDEFAIDNNISAISENSEGEEKDRPITKWFMFEEAKLDALRKKLYKNTNYKLPSLSMLSDKSNKESLRMLEFLDAMKKSIARILKNDTFIRKMQDGREDLSYMTNHFERENKGEIVSLAFSSVSSLPVYEADFGWGKPTWVTCATLLFSNLVIMIPTCPSNKDIVAYISLNAKDMGKLENDL
>AH001724-RA.v2.1
MSQSKGNTKTSLVFKVTRRAPELIAPAGPTPYEFKELSDIDDQEGLRFHIPGIYFYRDDKHFGGSPLERRDPAKVLKEAVAKALVSYYPLAGRLREREGRKLVVECNGEGIVFIEGDADVSLDEFGDVLLPPFPCFDELLFDAPGTTAILGAPLVLMQVTRLRCGGFIFAFRYNHTIADAQGILLFLNTIAKLARGEQSLLSQPVWERHLLNARNPPRVTCDHHEFDVVADTNNTIIPLEDTLHKSFFFALQPDPEELVRFMSIVNTRTLPNSPLPPGYYGNGFAFPVALSPAGMLSSNPIGPHFTVVRSFIVSDITKSGSEKLDIGWGLAVYGGPAKGGVGAIPGNGNGENGIAVPICLPANAMEIFEKELN
>AH000594-RA.v2.1
MSSLVFNVTMHAPELLPPAEQTPYEFKELSDIDDQDGLRFHIPSFLIYEHSGDQKDPVMVIKKAVAKALVSYYPFAGRLREKEGRKLVVECNGEGIIFIEANANVSLKIFGYPLLPPFPYLDELLWHVPGSNDILDAPLMLIQLSMPVGHNHCQRHPFGSATCLMLGNHPASLVTTVNMKRWPKQIAALRRLIPPHQKASTFEILSACLWRCRTIALQLHPQQLVRFMCIVNSRNLFNPPLPPGYYGNAFAFPVALSTVSKLSGNPIEYSLNLIQRAKSTVTEEYMKSVADFMVLNGRPRFSTSIYSFIVSDVTRSGSDNLDLGWGSPVYGGPAKGGVGAIPGISSFYIPFKNVNGEKGIVVPICLPANAMEIFVKEINGLLGSVLDNPNKRHGPSILISSL
>AH006574-RA.v2.1
MKISHVVVDGQSALHFMAEWARLARGEPLKMAPYIDPYMYQNQYLPKILTRNIHIEFNPAPFLVGEENNVKEREKATSVSILHLTKVHVEYLKKASNVKSKCHIRRPYTRYEVISAHIWKCACKARKHVYKQPTYLDFSIDVRNRVHPPLPPKYLGNAILDMVASSKSGEIMTRPLRYTCARIREAIEKVNDEYIWSNVDFWKSLPDLSPFQDIHDLRVKKVRFMVTNIGVIS
>AH006593-RA.v2.1
MFMNNQPIDIRNRVHPPLPPKYLGNAILDMVASSKSGEIMTRPLRYTCARIREAIEKVNDEYIWSNVDFWKSLPDLSPFQDIHGLKSKNGPFYGNPNIGVISWLTLPIYGLDFGWRKGDLYGPSQSCYLLASGPYG
>AH009923-RA.v2.1
MESLKKQAISKEGETLTLTTYAVQAGHLWRVVCKARGLADDQHVKLYIPINGRPRLKDREHTQGYFGNLLFHATCLEKAGDITSKPLSYVATKIQEAVQKMEDIEYLRSTIDYLESHPDLTAIVRGPYTFTSPNLMLNSWTRLPIHTVDFGWGTPYFMDIKGIPAEGIGFIKPSSDQDGRLIFNQQNGRYEIDCNAKGVLFSEVEITYCLDDLGDCMEHDPEVRKIIFPACDYTQELSSIPLLLAQLTRFKCGSVCIGLLQHHHVADGAAYLHFINSWARLANGRLDGGLLVQPIHDRAHYVGPREPPCVRFRHLIKGGRYHKQTLSYVATKIQEAVQKMEDIEYLRSTIDYLESHPDLTAIVRGPYTFTSPNLMLNSWTRLPIHTVDFGWGTPYFMDIKGIPAEGIGFIKPSSDQDGMRLIATRKEYYSEVETTYCLDHLGDCMEHDSETSQWRLDGGLLVQPIHDRAHYVGPREPPCVRFRPFHPCHPRAFQARGLADDQHVKLYIPINGRSRLKDREHTQAYFGNLLLHATCLEKAGDITSKPLSYAATKIQEVVQRMEDVEYLRSTIDFLESHPDLTAIVRGPYSFTSPNLLLNSWTRLPIHTADFGWGTPYFTGVKGIPAEGIGFIKPTSDLDGSFLIHIRLFAPHMDLFRRYLYEF
MTCSETVTIVSKSTVVPSQPSAMDDLKLSVSDLPMLSCHYIQKGGLFTKPPFNSSTLISYLKDGLSIALTQFPPLAGRFVTDSSGYVFITCNDAGVEFIHATAKNVFIRDIISPIDTPDIVKEFFSYDRIVSYKGHFQPLMAIQVTELADGVFISCAMNHSVTDGTSFWNFFNTFAESCRGVKRITKSPDFSRDSVLISSEILKIPEGGPVVTFNEKEPLRERIFSFSRESILELKSKVNNRKFSTPASIELLGKQSNDPYKDGKMVSKIENWIRNAVSVSKPQAINETDSMAVEISSFQSLCALLWRCVTRARKLNSTKTTTFRMAVNCRHRLEPKLNPLYFGNAIQSIPTVAVVDDVLSNDLRWAAEQLNKNVKDHGNDTVRKYVAEWESNPRTFPLGNFDGAMITMGSSPRFPMYDNDFGWGRPVVVRSGWANKFDGKISAFPGREGGGSVDLEVVLAPETMAGLESDPEFMQFVSSC
>AH018760-RA.v2.1
MAKIIKVIRQNPTLVVPSKPTKTEVKQLSDIDDQQGLRSHVYAIMSFKPNKSKEHPAKVIKQALSRALVYYYPLAGRLFKSRPDGKLMVHCNGEGVMFIEADAEVTLKEIQPYILPPCPLLKDFLFDEGSNMVQGSFYFDPKQVQSIRNLFPTNIQNSSTTFDLICACILRCRTIALKPDPEETITFSMLVNFRGKKIINLPKGYYGNALVTPGVTAKAKELLRENSWAYALKLVMESKEKANEEYVKSMIDYMAINGRPKYAKNLHFMAVNLPSLEVSGLDFGWGAPLYFGVARAYEIQSVFMKVKNGKGENVRLVSMLLPIQVMLRLQHELGKIMGEPFGSLTIDSAHISKL
>AH018423-RA.v2.1
MVRANKLDVNEVTYCSLLTNNRHRLNPPLNPYYFGTCISAVTASTEVGELLEHDLGWVANLVHESVVNHTNESVHDFYKEWMKDSFVYKHATLYDVNSITFENSPRFDMYGNEFGVGKPVAVRNGGGNKSVGVVNAFPGCEGNGSVDLEICLPFDSMSVFESDQELIAALLMP
>AH023054-RA.v2.1
MTCSDSLLTSPSVTIVSKSTVVPAEPSSMADLKLSVSDLPMLSCHYIQKGGLFTRPPMNSSNLISILKNGLSIALTNFPALAGRFVTDSLGYVFITCNDAGVDFVHATAKNVYVRDILSPTDVPDIVKEFFTYDRTVSYKGHFQPLMAVQVTELADGVFISCAMNHSVTDGTSFWNFFNTYAEICRGVKKITKSPEFSRDSILISPAILTVPEGGPVVTFNEREPLRERIFSFTREAIVELKSKVNNRKFSTVHPSIELIGKQSNDPYNDGKMTSKIENWIRNAITVSKPQSLNETETMAVEISSFQSLSALLWRSVTRARKLDPSKTSTFRMAVNCRHRLEPKLDPLYFGNAIQSIPTVAVMGDLLSNDLRWAAEQLNKNVRDHGNDTVRRCVAEWESNPRTFPLGNFDGAMITMGSSPRFPMYDNDFGWGRPVAVRSGRANKFDGKISAFPGRDGGGSVDLEVVLAPETMAGLESDPEFMQFVSVVR
>AH000084-RA.v2.1
MNTKIISKDIIKPYHPTPKNLRLLQASLFDHVNSPTLMPLIFFFSYPKTPTTTNITPTNKTLIKLKESLPITLSLFYPLAGRVRDVDHIDCNDEGVPYIETEVDQPLENIIHKVDVCHLDKLLPSYGHNKQGFTKLLLAIQINVFMCGGLAISVKMSHAISDAFSSFMFVNTWASIASSNKQHKITRFSPCFEISKAFPPLLSSNTKKYHIHSDDEFAIDNNISAISENSEGEEKDRPITKWFMFEEAKLDALRKKLYKNTNYKLPSLSMLSDKSNKESLRMLEFLDAMKKSIARILKNDTFIRKMQDGREDLSYMTNHFERENKGEIVSLAFSSVSSLPVYEADFGWGKPTWVTCATLLFSNLVIMIPTCPSNKDIVAYISLNAKDMGKLENDL
>AH001724-RA.v2.1
MSQSKGNTKTSLVFKVTRRAPELIAPAGPTPYEFKELSDIDDQEGLRFHIPGIYFYRDDKHFGGSPLERRDPAKVLKEAVAKALVSYYPLAGRLREREGRKLVVECNGEGIVFIEGDADVSLDEFGDVLLPPFPCFDELLFDAPGTTAILGAPLVLMQVTRLRCGGFIFAFRYNHTIADAQGILLFLNTIAKLARGEQSLLSQPVWERHLLNARNPPRVTCDHHEFDVVADTNNTIIPLEDTLHKSFFFALQPDPEELVRFMSIVNTRTLPNSPLPPGYYGNGFAFPVALSPAGMLSSNPIGPHFTVVRSFIVSDITKSGSEKLDIGWGLAVYGGPAKGGVGAIPGNGNGENGIAVPICLPANAMEIFEKELN
>AH000594-RA.v2.1
MSSLVFNVTMHAPELLPPAEQTPYEFKELSDIDDQDGLRFHIPSFLIYEHSGDQKDPVMVIKKAVAKALVSYYPFAGRLREKEGRKLVVECNGEGIIFIEANANVSLKIFGYPLLPPFPYLDELLWHVPGSNDILDAPLMLIQLSMPVGHNHCQRHPFGSATCLMLGNHPASLVTTVNMKRWPKQIAALRRLIPPHQKASTFEILSACLWRCRTIALQLHPQQLVRFMCIVNSRNLFNPPLPPGYYGNAFAFPVALSTVSKLSGNPIEYSLNLIQRAKSTVTEEYMKSVADFMVLNGRPRFSTSIYSFIVSDVTRSGSDNLDLGWGSPVYGGPAKGGVGAIPGISSFYIPFKNVNGEKGIVVPICLPANAMEIFVKEINGLLGSVLDNPNKRHGPSILISSL
>AH006574-RA.v2.1
MKISHVVVDGQSALHFMAEWARLARGEPLKMAPYIDPYMYQNQYLPKILTRNIHIEFNPAPFLVGEENNVKEREKATSVSILHLTKVHVEYLKKASNVKSKCHIRRPYTRYEVISAHIWKCACKARKHVYKQPTYLDFSIDVRNRVHPPLPPKYLGNAILDMVASSKSGEIMTRPLRYTCARIREAIEKVNDEYIWSNVDFWKSLPDLSPFQDIHDLRVKKVRFMVTNIGVIS
>AH006593-RA.v2.1
MFMNNQPIDIRNRVHPPLPPKYLGNAILDMVASSKSGEIMTRPLRYTCARIREAIEKVNDEYIWSNVDFWKSLPDLSPFQDIHGLKSKNGPFYGNPNIGVISWLTLPIYGLDFGWRKGDLYGPSQSCYLLASGPYG
>AH009923-RA.v2.1
MESLKKQAISKEGETLTLTTYAVQAGHLWRVVCKARGLADDQHVKLYIPINGRPRLKDREHTQGYFGNLLFHATCLEKAGDITSKPLSYVATKIQEAVQKMEDIEYLRSTIDYLESHPDLTAIVRGPYTFTSPNLMLNSWTRLPIHTVDFGWGTPYFMDIKGIPAEGIGFIKPSSDQDGRLIFNQQNGRYEIDCNAKGVLFSEVEITYCLDDLGDCMEHDPEVRKIIFPACDYTQELSSIPLLLAQLTRFKCGSVCIGLLQHHHVADGAAYLHFINSWARLANGRLDGGLLVQPIHDRAHYVGPREPPCVRFRHLIKGGRYHKQTLSYVATKIQEAVQKMEDIEYLRSTIDYLESHPDLTAIVRGPYTFTSPNLMLNSWTRLPIHTVDFGWGTPYFMDIKGIPAEGIGFIKPSSDQDGMRLIATRKEYYSEVETTYCLDHLGDCMEHDSETSQWRLDGGLLVQPIHDRAHYVGPREPPCVRFRPFHPCHPRAFQARGLADDQHVKLYIPINGRSRLKDREHTQAYFGNLLLHATCLEKAGDITSKPLSYAATKIQEVVQRMEDVEYLRSTIDFLESHPDLTAIVRGPYSFTSPNLLLNSWTRLPIHTADFGWGTPYFTGVKGIPAEGIGFIKPTSDLDGSFLIHIRLFAPHMDLFRRYLYEF
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University