Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Juglans regia
Species name
English walnut (Juglans regia) is a species of eudicot in the family Juglandaceae (walnut family).
Species info
Gene sequence info
Juglans_regia.CHS.fa
Download
>rna-XM_018978491.2
MASVEEFLKAQRSEGPATVLAIGTANPSNCISQTDFPDYYFRITKSEHLTELKKKFKRMCDKSMINKRYMHLTEDILKENPGMCEFMAPSYDARQDIAVVELPKLAKEAALKAIKEWGQHKSKITHLVFCTTTGTADMPGADYQLIKLLGLKSSVKRVMMYQQGCFGGGTVLRLAKDLAENNRGARVLAVCAEIVAISFRGPSEAHFDSLVGQSLFGDGAAAVIIGADPDTSVERPLFQLVSAAQTILPDSDGAVQGHLREVGLTFHALKDLPKIVSRNVEQSLVEAFTPFGVSDWNSIFWIVHPGGPAILDQVEAKLSLQEEKLRASRHILSEYGNMSTACVLFILDEMRKSSVEDGKATTGGGLEWGVLFGFGPGLTVETVVLRSVPVETIH
>rna-XM_018952137.2
MASVEKIREAQRAKGPATILAIGSANPPNCIYQSDYPNFYFGATNSDHMTELKHKFKRICEKSMIRKRFFHLTEEILKANPNIGNYKAPSLNLRQDVGVADVTKIGGEAALKAIKEWGQPISKITHLVFCTMTGFDMPGADFQLIKLLGLNPSVNRCMIYQQGCYAGGTALRLAKDLAENNASARVLVVCSENMTMSFHGPSESHLDILIGQAIFSDGAAAAIVGASPDTLTEHPLFELIWATQSIIPDTEDGVVGKLREMGMTYHLSTNLAEFIGNNIENCMIEAFSSIGISDWNSLFFIVHPGGPLILHKIQENLGLNEEKLKTSRHVLREYGNMASPCVLFILDKMREKSMEEGKATTGDGLEWGVLFGFGPGLTVEAIVLHSIPVKNINAC
>rna-XM_035690857.1
MLQIKFKVSPFVSTDIWIYIYQKKDVICNHSGFPKIELYPLYSYWCKWTPMALSAPRHGQPAQVLAIGTANPVNSIDQKDFPDFYLRVTKSEHMTELKEQLKFICEESSIRKRHLLLTEEILANPNIGGSEFRSLNALQAMGAPEVIKLGKEAATKAIKEWGQPISKITHLVFCTRFGWDVPSPAYQLTELLGLNTSVETYMIDEHCHAGGIGLRLAMYIAERNATARILVVYSENTAVLFEGPSDDQTDVQKLNTYAHCADGAAAAIIGACPDTWTENPLFELVVACKSVLPDSEGALASFLREMRQSFYLSENYMPILDGNNMEKSLVDAQIWAERLRQTGISDLNSLFYVVNTGLGRLLDNFEENLGLSDGKLRASWHVLREYGYVMGPGLLFVLDEMRNKSMKEGETTTGHGLEWGVLFGFGPDHELETFVVRSIPIIPNPFVGAVNFLLKWFATKLMW
>rna-XM_018961711.2
MVTVEDVRRAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAIIIGADPIPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGITDWNSLFWIAHPGGPAILDQVEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRRKSVEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLSA
>rna-XM_018966498.2
MASMEEIRKAQRAQGPANILAIGTATPSNCVSQADYPDFYFRITKSEHMTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMAPSLDARQDIVVLEVPKLGKEAASKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAALIVGSDPDTSVERPLYQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKMRATRQVLSEYGNMSSACVLFILDEMRKKSAKEGKATTGEGLEWGVLFGFGPGLTVETIVLHSVNI
>rna-XM_018971548.2
MVTVEDVRRAQRAEGPATVMAIGTATPPNCVDQSAYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGITDWNSLFWIAHPGGPAILDQVESKLELKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDRLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>rna-XM_018959798.2
MGTVGVAGGGSTKVANPGKATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNDAVTRMAVEASQACLKNWGRSPSDITHLVYVSSSEARLPGGDLYLAKGLGLSPETQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAERPYDLVGVALFGDGAGAMIIGSDPVLGYEKPLFELHTAIQQFLPNTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLMEVDGFPDKEYNKMFWAVHPGGPAILNRMEKRLDLSPEKLNASRRALMDYGNASSNTIVYVLEYMIEESLKMKKENQGDDDEWGLILAFGPGISFEGVLARNLTG
>rna-XM_035685346.1
MATISSSRSRLFALVRMPFSMPSSQHRSTPRCYCSQQSITSIEDDKNGNEELDRFVKSKASAKTKRAKAMARLINYKPWSSELESSLSSLSPSLSKTAVLQTLRLIRTPSKAFQFFNWVHEMGFSHTDQSYFMMLEILGRDRNLNVARNLLFSMEKRSNGVVKLEDRFFNSLIRNYGRAGLFQESIKLFTTMKSLGVSPSVVTFNSILTILLRRGRTNMAKDMYDEMLRTYGVTPDTYTFNILIRGFCKNSMVDEGFQFFKLMSHFSCEPDVVTYNTLVDGLCRVGKARIAHNVVKGMSKKSMDLNPNVVTYTALIRGYCMKQEIDVALVLLEEMTSQGLKPNIITYNTLIKGLCEAQNLEKIKEILEGMMEVGGFTPDTCTFNTIIHAHCSAGNLDEALNVFEKMSELQVLPDSATYSVLIRSLCQIGDYSRAEKLFGELSEKKILLCDVGCKPLVAAYNPMFEYLCGNGKTNKAERVFRQLMKRGRQDPPSYKTLIMGHCREGTYEAGYELVVWMLRRDFVPDFEIYESLIGGFLQKGKPLLAQQTLEKMLKSSHLPKTSTFHSILAELIEKGCARESSSFIMLMLERKIRQNINLSTNCIRLLLDRGLRDKAFRIVGMIYENGYSVKIEELVGFLCQSRKLLEARDMFLFSLDKHQNIDTNTCNTLIAGLCKMKKLSEAFGLYYELVEKGVHQQLTCLYDLKTALDAGGRSDQAEFVSKRMPGQEHLDKPASKSRPKQLLGGRGHENRMESLHGINPHTSNPRTQKATKPIKVNISSIFMLLFLGTNLSPRTNQLPHLYSPIQTQIYLL*QQLHKMSRTNGNGAVNEYPAQIRRIPTPGKATVLALGKAFPSQLIPQECLVEGYIRDTKCEDLSIKEKLERLCKTTTVKTRYTVMSKEILDKYPELVTEGSPTIKQRLEIANPAVLEMAMEASLACIKEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGTNPLKGQESPFMELNYAVQQFLPGTHTVIDGKLSEEGINFRLGRDLPQKIEDNIEEFCKKLMAKANLINFNDLFWAVHPGGPAILNRLESTLNLTSEKLECSRRALMDYGNVSSNTIFYVIDYMREELKRGTEEWGLALAFGPGITFEGILIRCL
>rna-XM_018996379.2
MASVEKIREPQRAHGPATILAIGTANPANCIYQKDYPDFYFRVTKSEHMTELKEKFKRICEKSRITKRYFHLTEEILKANPNMCKYKAPSLNARQDIVVTEVPSLGKAAALKAIEEWGQPISKITHLVFCTMTGIDMPGADYQLTKLLGLNSSINRYMIYQQGCHAGGTALRLAKDLAENNASARVLVVCSENTTMLFNGPSETHLDILVGQAIFADGAAAAIIGANPDNSIEHPLFEIAWARQSIVPGSEGAIVDHIREMGISLYLARNLPKLVGSNIKNNMAEAFTPIGIKDWNSLFYVVHTGGAAILDQIQENLGLKEDKLRASRHVLSNYGNVGSPCVLFILDEVRKKSLEEGKTTTGDGLEWGVLFGFGPGLTVEAVVLHSIPIREKTTTKKRYFHLTEEILKENPSMCKYGAPSLDARQEMVVPEVPKLGKEAALKAIQEWGQPVSKITHLVFCTSSGVDMPGADYQLTKLLGLNPSVNRYMIYKQNSYAGGTALRIAKDLAENNAGARVLVVCSEIVAMFFHGPSENHLDILKSQALFADGAAAVIVGANLDTLTEHPLFELVWASQAIVPNTEGASVGYLREMGVTFHLSETLPYVIGSNIENSMATAFSSISGGISDWNSLFYVVHPGLGTILDQIQENLGLKEDKLKASWHVLSEYGNMLGPSVLFVLDEMRKKSKEEGKKTTGDGLEWGVLFGFGSGLTVETVVLHSIPIITPPCGSATS
>rna-XM_018985888.2
MGSEDVAQGGSTKWANPGKATILALGKAFPHQLVMQDYLVDGYFKDTNCDDPVLKQKLTRLCKTTTVQTRYVVMSEEILKKYPELAVEGLPTLRQRLDICNDAVTRMAVEASQACLKNWGRPISDITHLVYVSSSEARLPGGDLYLAKGLGLSPNTQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAERPYDLVGVALFGDGAGAMLIGSDPVLGYEKPLFELHTAIQQFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCTKLVKVVGFPDKEYNKMFWAVHPGGPAILNRMEKRLELLPEKLNASRRALMDYGNASSNTIVYVLEYMIEENLKIKKENQGDNEWGLILAFGPGISFEGILARNLTV
MASVEEFLKAQRSEGPATVLAIGTANPSNCISQTDFPDYYFRITKSEHLTELKKKFKRMCDKSMINKRYMHLTEDILKENPGMCEFMAPSYDARQDIAVVELPKLAKEAALKAIKEWGQHKSKITHLVFCTTTGTADMPGADYQLIKLLGLKSSVKRVMMYQQGCFGGGTVLRLAKDLAENNRGARVLAVCAEIVAISFRGPSEAHFDSLVGQSLFGDGAAAVIIGADPDTSVERPLFQLVSAAQTILPDSDGAVQGHLREVGLTFHALKDLPKIVSRNVEQSLVEAFTPFGVSDWNSIFWIVHPGGPAILDQVEAKLSLQEEKLRASRHILSEYGNMSTACVLFILDEMRKSSVEDGKATTGGGLEWGVLFGFGPGLTVETVVLRSVPVETIH
>rna-XM_018952137.2
MASVEKIREAQRAKGPATILAIGSANPPNCIYQSDYPNFYFGATNSDHMTELKHKFKRICEKSMIRKRFFHLTEEILKANPNIGNYKAPSLNLRQDVGVADVTKIGGEAALKAIKEWGQPISKITHLVFCTMTGFDMPGADFQLIKLLGLNPSVNRCMIYQQGCYAGGTALRLAKDLAENNASARVLVVCSENMTMSFHGPSESHLDILIGQAIFSDGAAAAIVGASPDTLTEHPLFELIWATQSIIPDTEDGVVGKLREMGMTYHLSTNLAEFIGNNIENCMIEAFSSIGISDWNSLFFIVHPGGPLILHKIQENLGLNEEKLKTSRHVLREYGNMASPCVLFILDKMREKSMEEGKATTGDGLEWGVLFGFGPGLTVEAIVLHSIPVKNINAC
>rna-XM_035690857.1
MLQIKFKVSPFVSTDIWIYIYQKKDVICNHSGFPKIELYPLYSYWCKWTPMALSAPRHGQPAQVLAIGTANPVNSIDQKDFPDFYLRVTKSEHMTELKEQLKFICEESSIRKRHLLLTEEILANPNIGGSEFRSLNALQAMGAPEVIKLGKEAATKAIKEWGQPISKITHLVFCTRFGWDVPSPAYQLTELLGLNTSVETYMIDEHCHAGGIGLRLAMYIAERNATARILVVYSENTAVLFEGPSDDQTDVQKLNTYAHCADGAAAAIIGACPDTWTENPLFELVVACKSVLPDSEGALASFLREMRQSFYLSENYMPILDGNNMEKSLVDAQIWAERLRQTGISDLNSLFYVVNTGLGRLLDNFEENLGLSDGKLRASWHVLREYGYVMGPGLLFVLDEMRNKSMKEGETTTGHGLEWGVLFGFGPDHELETFVVRSIPIIPNPFVGAVNFLLKWFATKLMW
>rna-XM_018961711.2
MVTVEDVRRAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAIIIGADPIPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGITDWNSLFWIAHPGGPAILDQVEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRRKSVEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSLSA
>rna-XM_018966498.2
MASMEEIRKAQRAQGPANILAIGTATPSNCVSQADYPDFYFRITKSEHMTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMAPSLDARQDIVVLEVPKLGKEAASKAIKEWGQPKSRITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAALIVGSDPDTSVERPLYQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGISDWNSLFWIAHPGGPAILDQVEAKLGLKEEKMRATRQVLSEYGNMSSACVLFILDEMRKKSAKEGKATTGEGLEWGVLFGFGPGLTVETIVLHSVNI
>rna-XM_018971548.2
MVTVEDVRRAQRAEGPATVMAIGTATPPNCVDQSAYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGITDWNSLFWIAHPGGPAILDQVESKLELKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDRLKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>rna-XM_018959798.2
MGTVGVAGGGSTKVANPGKATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNDAVTRMAVEASQACLKNWGRSPSDITHLVYVSSSEARLPGGDLYLAKGLGLSPETQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAERPYDLVGVALFGDGAGAMIIGSDPVLGYEKPLFELHTAIQQFLPNTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLMEVDGFPDKEYNKMFWAVHPGGPAILNRMEKRLDLSPEKLNASRRALMDYGNASSNTIVYVLEYMIEESLKMKKENQGDDDEWGLILAFGPGISFEGVLARNLTG
>rna-XM_035685346.1
MATISSSRSRLFALVRMPFSMPSSQHRSTPRCYCSQQSITSIEDDKNGNEELDRFVKSKASAKTKRAKAMARLINYKPWSSELESSLSSLSPSLSKTAVLQTLRLIRTPSKAFQFFNWVHEMGFSHTDQSYFMMLEILGRDRNLNVARNLLFSMEKRSNGVVKLEDRFFNSLIRNYGRAGLFQESIKLFTTMKSLGVSPSVVTFNSILTILLRRGRTNMAKDMYDEMLRTYGVTPDTYTFNILIRGFCKNSMVDEGFQFFKLMSHFSCEPDVVTYNTLVDGLCRVGKARIAHNVVKGMSKKSMDLNPNVVTYTALIRGYCMKQEIDVALVLLEEMTSQGLKPNIITYNTLIKGLCEAQNLEKIKEILEGMMEVGGFTPDTCTFNTIIHAHCSAGNLDEALNVFEKMSELQVLPDSATYSVLIRSLCQIGDYSRAEKLFGELSEKKILLCDVGCKPLVAAYNPMFEYLCGNGKTNKAERVFRQLMKRGRQDPPSYKTLIMGHCREGTYEAGYELVVWMLRRDFVPDFEIYESLIGGFLQKGKPLLAQQTLEKMLKSSHLPKTSTFHSILAELIEKGCARESSSFIMLMLERKIRQNINLSTNCIRLLLDRGLRDKAFRIVGMIYENGYSVKIEELVGFLCQSRKLLEARDMFLFSLDKHQNIDTNTCNTLIAGLCKMKKLSEAFGLYYELVEKGVHQQLTCLYDLKTALDAGGRSDQAEFVSKRMPGQEHLDKPASKSRPKQLLGGRGHENRMESLHGINPHTSNPRTQKATKPIKVNISSIFMLLFLGTNLSPRTNQLPHLYSPIQTQIYLL*QQLHKMSRTNGNGAVNEYPAQIRRIPTPGKATVLALGKAFPSQLIPQECLVEGYIRDTKCEDLSIKEKLERLCKTTTVKTRYTVMSKEILDKYPELVTEGSPTIKQRLEIANPAVLEMAMEASLACIKEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGTNPLKGQESPFMELNYAVQQFLPGTHTVIDGKLSEEGINFRLGRDLPQKIEDNIEEFCKKLMAKANLINFNDLFWAVHPGGPAILNRLESTLNLTSEKLECSRRALMDYGNVSSNTIFYVIDYMREELKRGTEEWGLALAFGPGITFEGILIRCL
>rna-XM_018996379.2
MASVEKIREPQRAHGPATILAIGTANPANCIYQKDYPDFYFRVTKSEHMTELKEKFKRICEKSRITKRYFHLTEEILKANPNMCKYKAPSLNARQDIVVTEVPSLGKAAALKAIEEWGQPISKITHLVFCTMTGIDMPGADYQLTKLLGLNSSINRYMIYQQGCHAGGTALRLAKDLAENNASARVLVVCSENTTMLFNGPSETHLDILVGQAIFADGAAAAIIGANPDNSIEHPLFEIAWARQSIVPGSEGAIVDHIREMGISLYLARNLPKLVGSNIKNNMAEAFTPIGIKDWNSLFYVVHTGGAAILDQIQENLGLKEDKLRASRHVLSNYGNVGSPCVLFILDEVRKKSLEEGKTTTGDGLEWGVLFGFGPGLTVEAVVLHSIPIREKTTTKKRYFHLTEEILKENPSMCKYGAPSLDARQEMVVPEVPKLGKEAALKAIQEWGQPVSKITHLVFCTSSGVDMPGADYQLTKLLGLNPSVNRYMIYKQNSYAGGTALRIAKDLAENNAGARVLVVCSEIVAMFFHGPSENHLDILKSQALFADGAAAVIVGANLDTLTEHPLFELVWASQAIVPNTEGASVGYLREMGVTFHLSETLPYVIGSNIENSMATAFSSISGGISDWNSLFYVVHPGLGTILDQIQENLGLKEDKLKASWHVLSEYGNMLGPSVLFVLDEMRKKSKEEGKKTTGDGLEWGVLFGFGSGLTVETVVLHSIPIITPPCGSATS
>rna-XM_018985888.2
MGSEDVAQGGSTKWANPGKATILALGKAFPHQLVMQDYLVDGYFKDTNCDDPVLKQKLTRLCKTTTVQTRYVVMSEEILKKYPELAVEGLPTLRQRLDICNDAVTRMAVEASQACLKNWGRPISDITHLVYVSSSEARLPGGDLYLAKGLGLSPNTQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAERPYDLVGVALFGDGAGAMLIGSDPVLGYEKPLFELHTAIQQFLPDTEKTIDGRLTEEGISFKLARELPQIIEDNIEGFCTKLVKVVGFPDKEYNKMFWAVHPGGPAILNRMEKRLELLPEKLNASRRALMDYGNASSNTIVYVLEYMIEENLKIKKENQGDNEWGLILAFGPGISFEGILARNLTV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University