Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Jatropha curcas
Species name
Jatropha curcas is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Jatropha_curcas.COMT.fa
Download
>rna-XM_012232935.3
MSSPAEMAYQKPSANDDDLDEEESFSYAVQISMGIVLPMVMQTAIELGIFDIIAKAGPDAKLSASDIAAQLSASNPSAPSMLDRILRLLASNSVLGCSLASNTQQRLYHLISASKYFVKNKDGVSLGPFMILNQDKVYMESWPSVKDAILEGGIPFNKVHGMHAFDYPATDPRFNKVFNTGMINHTTIVINKMLESYKGFDNLNQLVDVGGGLGVTLHMITSKYTQIKGINFDLPRVIQHALPYPGVDHVEGDMFESVPEGDAIFMKWILHDWSDEHCLMLLKNCYKAIPEDGKVIVLDAVLPTMAEKSAAATRDTYLMDVFMMTQNPGGKERTRQEFLALAIDSGFSGIRFQSCVCNFWVMEFFK
>rna-XM_037635723.1
MGAYLSAKEIASQLPTKNSQASQMVDRILRLLASYSVVTCTNSVNKLDGDNNSTNWLYGLAPISKYFLNSEGNTSLAPPMHLLHCKAFMDSWYGLEDAVLEGGVPFNRVHEMHVYEYTAKFPQFNELFNKAMINLTRLLMENILDKYKGFKNQETHIFNKLSQCNKNLHYALQSSSIRDRISLTHKV
>rna-XM_037635724.1
MGAYLSAKEIASQLPTKNSQASQMVDRILRLLASYSVVTCTNSVNKLDGDNNSTNWLYGLAPISKYFLNSEGNTSLAPPMHLLHCKAFMDSWYGLEDAVLEGGVPFNRVHEMHVYEYTAKFYEYTAKFPQFNELFNKAMINLTRLLMENILDKYKGFKNLKELVDVGGGLGLTLQMITSKYPNIKAINFDLPHVIQDAPPYSGVQYISGDMFTKVPKGEAILLKFILHNWNDDRCLRLLKNCYASETVDTNEENKNHFSQLEFNYAVPNC
>rna-XM_020682566.2
MAMEDESSESRNRARLAILELANMISVPMSLNAIVRLNVADVIWQGGANAPLSASEILARVHPSGGDPENLQRILRMLTSYDVFTEHVNSDATERRYSLTEIGKTLVTDSEGLSYASYVLQHHQDALMRAWPLVHEAVVDPTTEPFVKANDEPAYAYYGKQPEMNGLMQKAMSGVSVPFMKAILNGYDGFQGMEKLVDVGGSAGDCLRMILKKYPNIREGINFDLPEVVAKAPNIPGVTHVGGDMFKSIPSADGIFMKAWQWVLTTWTDEECKQIMENCYKALPVGGKLIACEPVLPKQSDDSHRTRALLEGDIFVMTIYRAKGKHRTAEEFKLLGQSVGFSHFQAFYIDYFYTVLEFHK
>rna-XM_037636856.1
MGSTGETQMTPAQVSDEEANLFAMQLASASTLPMVLKSAIELDLLEIIAKAGPGAFLSPHDIASQLPTKNPDAPLVLDRILRLLASYSILTCSLRTLPDEKFERLYGLAPVCKFLTKNEDGVSFASICVMIQDKVLMESWF
>rna-XM_037640826.1
MTPTSKNRSGPGAFCPPNTTSLSSFPTREPTTPSVLDRILAAAASYSILYYSLRNSSDGKVEKLYGLAPVCKFLTQRR*GRCLLLPPLCLMNQE*SKLMESWYYLKEAVLDRRNFKLPFNKAHGMDEFEYHGTDPRFSKVFNMGMSNHSTVTMKKILETYKGFEGLTSLVDVGGGTGAVINMIVSKYPSLKGINFDLPHVIEGAPSYPGVEHDSGDMFVSVPKADAIFVKSVCHNWSDEHCLKFLKNFCDALPVNGKVIVADYVLPVAPDTSLATKGVIHMDCIMLALQSGGKERTENEFEALAKGAGFTGFQVTCSAFNTCVMEFIKKA
>rna-XM_037640820.1
MTLFEYHGTDPRFNKVFNEGMSYHSTIIMRKILETYKGFEGLTSLVDVGGGIGAVLNMIVTKYPSMKGINFDLPHVIEDAPSFPGVEHVGGDMFVTAPKGDAIFMKWICHDWSDEYCLKLLKNCYNAIPANGKVIVAEYILPVAPDTSLATKAVIHMDCLMLAHLPGGKERTEEEFETLAKGAGFQGFQVICSAFNTYVMEFLKKA
>rna-XM_012222981.3
MAWGSLRLRLLLKYPQRTQMHQLCSTVCCVSWQAMTYSTAPKRMDKVKDCTLPDPYASSSLEMIQNDSNEGSSVSPLFLLHHDEVFMKSWYHFNEAILEGGIPFTIQTYGMTVFEYQATDQRFNQVFNEAMSNHTTLFVKKIIEVYDGFDGVKVLVDVGGGIGDALRIITSKYPHIKGINFDLPNVLADAPSFPGVEHVAGDMFVSVPKGDAIFMKWILHGWSDEYCLKLLKNCYEALPSKGKVIVAESILPLAPENAVSSHIVFEQDLFMFAQTPGGKERTQKDYETLAMKSGFSSCEVVCCAYNSWVMEFHKA
>rna-XM_020681265.2
MFVSVPKGDAIFMKWILHGWSDEYCLKLLKNCYEALPSKGKVIVAESILPLAPENAVSSHIVFEQDLFMFAQTPGGKERTQKDYETLAMKSGFSSCEVVCCAYNSWVMEFHKA
>rna-XM_037641208.1
MTNYSTSKFAVNYNLDQEEEQETGKLALRLANAIVLPMVLKSAIELNIIDIVSTATSNGLGISPVEIAAQIPTKNPDAPVLLDRMLRLLASYDILNCTKENGRDERLYSARSICKFLTRNDSNEGSSVSPLFLLHHDEVFMKTWYHFNEAILEGGIPFNKTYGMTVFEYQGTDQRFNKVFNEAMSNHTSLIVKKIIKVYNGFDGVKVLVDVGGGIGVTLRIITSKYPHIKGINFDLSHVSADAPSFPGVEHVVGDMFVSVPKGDAISMKWILHDWSDDYCLKLLKNCYEALPSKGKVIVVESILPLVAENAVSSHIVYKQDLFMFAQTPGGKERTQKDYETLAIKSGFSSCKVVCCAYNSWVMEFHKA
>rna-XM_037641599.1
MSLAENHIDEEACLNAMIFSSSHVFPFVLHTAIELNLFGIIAKAGPGAFVSASEIASQLPTTNPDAPSMLDRMLHLFASHSLLSYSSRTLKDGSIQKLYGLTPACKFFIGSVEEGNISSFSYLSYHRATVEVWLNMKDAILEGGNLFKKVHGMSVFEYMNRDPEFNNIFNQAMAGLSSVIMSGILAKYKGFEGLTSLVDVGGGTGRTLHMIISKYPSIKGINYDLPHVIQSAPPYAGIQHVGGNMFTGVPKGDAIMIKETCHNWSDDNVVRVLKNIYEVLPENGKLIILNALLPEEPETSKASQYVSRTDNLMLTQPGGKERTAREFAALTKAAGFTNFRVASVADGICAVMESYK
>rna-XM_037641598.1
MSLAENQIDEEACLNAMIFSSSHVFPFVLHTAIELNLFGIIAKAGPGAFVSASEIASQLPTTNPDAPSMLDRMLHLFASHSLLSYSSRTLKDGSVQKLYGLTPACKFFIGSVEEGNISSLSSLSYLRATVEVWLNMKDAILEGGNLFKKVHGMSIFEYMNRDPEFNTIFNQAMAGLSSVIMNGILAKYKGFEGLTSLVDVGGGTGRTLNMIISKYPSIKGINYDLPHVIQSAPPYTGIQHIGGNMLTCVPKGDAIMIKDTCHNWRDDDVVRVLKNIYEVLPENGKLVILNALLPEEPETSKASQYVSRLDNTMLTQPCGKERTAREFEALTKAAGFTNFRVACVAHGIWAVMESYK
>rna-XM_037641600.1
MIISKYPSIKGINYDLPHVIQSAPPYTGIQHVGGNMFTGIPKGDAIMIKDTCHNWSDDNVVRLLKNIYEVLPENGKLIILNALLPEEPETSKASQYVSRLDNVMLAQPGGKERTAREFEALTEAAGFTNFLVACVAHGIWAVMESYK
>rna-XM_012215526.3
MDSNSINEINEEDEAHLNAMLFSASHIFPMVFRAAIQLNIFGIIAKAGPNAYLSATDIAFHLPTQNPEAPSMLDRMLLLFASHSLLSQSKRTLEDGQVETLYGLTPTSKFFVPCSEEEGGSLAPLSALSTHKVAMEVWLNLKDAILEGGSMFKRVHGMSLFEYMNEDQAFNKIFNDAMAGLSPLIMNAIFQRYKGFEGLNSLVDVGGGTGKVLNMIISKYPSIKGINYDLPHVTLTAPPYPGIQHIGGNMLTSVPQGDAVMIKDTCHNWSDENVIKVLKNVYEVLPKNGKLIIINAILPEEPDTTKASQYVLSLNNTMLMQPGGKERTAKQFESFTKAAGFSNFNVACVARGIWAVMESCK
MSSPAEMAYQKPSANDDDLDEEESFSYAVQISMGIVLPMVMQTAIELGIFDIIAKAGPDAKLSASDIAAQLSASNPSAPSMLDRILRLLASNSVLGCSLASNTQQRLYHLISASKYFVKNKDGVSLGPFMILNQDKVYMESWPSVKDAILEGGIPFNKVHGMHAFDYPATDPRFNKVFNTGMINHTTIVINKMLESYKGFDNLNQLVDVGGGLGVTLHMITSKYTQIKGINFDLPRVIQHALPYPGVDHVEGDMFESVPEGDAIFMKWILHDWSDEHCLMLLKNCYKAIPEDGKVIVLDAVLPTMAEKSAAATRDTYLMDVFMMTQNPGGKERTRQEFLALAIDSGFSGIRFQSCVCNFWVMEFFK
>rna-XM_037635723.1
MGAYLSAKEIASQLPTKNSQASQMVDRILRLLASYSVVTCTNSVNKLDGDNNSTNWLYGLAPISKYFLNSEGNTSLAPPMHLLHCKAFMDSWYGLEDAVLEGGVPFNRVHEMHVYEYTAKFPQFNELFNKAMINLTRLLMENILDKYKGFKNQETHIFNKLSQCNKNLHYALQSSSIRDRISLTHKV
>rna-XM_037635724.1
MGAYLSAKEIASQLPTKNSQASQMVDRILRLLASYSVVTCTNSVNKLDGDNNSTNWLYGLAPISKYFLNSEGNTSLAPPMHLLHCKAFMDSWYGLEDAVLEGGVPFNRVHEMHVYEYTAKFYEYTAKFPQFNELFNKAMINLTRLLMENILDKYKGFKNLKELVDVGGGLGLTLQMITSKYPNIKAINFDLPHVIQDAPPYSGVQYISGDMFTKVPKGEAILLKFILHNWNDDRCLRLLKNCYASETVDTNEENKNHFSQLEFNYAVPNC
>rna-XM_020682566.2
MAMEDESSESRNRARLAILELANMISVPMSLNAIVRLNVADVIWQGGANAPLSASEILARVHPSGGDPENLQRILRMLTSYDVFTEHVNSDATERRYSLTEIGKTLVTDSEGLSYASYVLQHHQDALMRAWPLVHEAVVDPTTEPFVKANDEPAYAYYGKQPEMNGLMQKAMSGVSVPFMKAILNGYDGFQGMEKLVDVGGSAGDCLRMILKKYPNIREGINFDLPEVVAKAPNIPGVTHVGGDMFKSIPSADGIFMKAWQWVLTTWTDEECKQIMENCYKALPVGGKLIACEPVLPKQSDDSHRTRALLEGDIFVMTIYRAKGKHRTAEEFKLLGQSVGFSHFQAFYIDYFYTVLEFHK
>rna-XM_037636856.1
MGSTGETQMTPAQVSDEEANLFAMQLASASTLPMVLKSAIELDLLEIIAKAGPGAFLSPHDIASQLPTKNPDAPLVLDRILRLLASYSILTCSLRTLPDEKFERLYGLAPVCKFLTKNEDGVSFASICVMIQDKVLMESWF
>rna-XM_037640826.1
MTPTSKNRSGPGAFCPPNTTSLSSFPTREPTTPSVLDRILAAAASYSILYYSLRNSSDGKVEKLYGLAPVCKFLTQRR*GRCLLLPPLCLMNQE*SKLMESWYYLKEAVLDRRNFKLPFNKAHGMDEFEYHGTDPRFSKVFNMGMSNHSTVTMKKILETYKGFEGLTSLVDVGGGTGAVINMIVSKYPSLKGINFDLPHVIEGAPSYPGVEHDSGDMFVSVPKADAIFVKSVCHNWSDEHCLKFLKNFCDALPVNGKVIVADYVLPVAPDTSLATKGVIHMDCIMLALQSGGKERTENEFEALAKGAGFTGFQVTCSAFNTCVMEFIKKA
>rna-XM_037640820.1
MTLFEYHGTDPRFNKVFNEGMSYHSTIIMRKILETYKGFEGLTSLVDVGGGIGAVLNMIVTKYPSMKGINFDLPHVIEDAPSFPGVEHVGGDMFVTAPKGDAIFMKWICHDWSDEYCLKLLKNCYNAIPANGKVIVAEYILPVAPDTSLATKAVIHMDCLMLAHLPGGKERTEEEFETLAKGAGFQGFQVICSAFNTYVMEFLKKA
>rna-XM_012222981.3
MAWGSLRLRLLLKYPQRTQMHQLCSTVCCVSWQAMTYSTAPKRMDKVKDCTLPDPYASSSLEMIQNDSNEGSSVSPLFLLHHDEVFMKSWYHFNEAILEGGIPFTIQTYGMTVFEYQATDQRFNQVFNEAMSNHTTLFVKKIIEVYDGFDGVKVLVDVGGGIGDALRIITSKYPHIKGINFDLPNVLADAPSFPGVEHVAGDMFVSVPKGDAIFMKWILHGWSDEYCLKLLKNCYEALPSKGKVIVAESILPLAPENAVSSHIVFEQDLFMFAQTPGGKERTQKDYETLAMKSGFSSCEVVCCAYNSWVMEFHKA
>rna-XM_020681265.2
MFVSVPKGDAIFMKWILHGWSDEYCLKLLKNCYEALPSKGKVIVAESILPLAPENAVSSHIVFEQDLFMFAQTPGGKERTQKDYETLAMKSGFSSCEVVCCAYNSWVMEFHKA
>rna-XM_037641208.1
MTNYSTSKFAVNYNLDQEEEQETGKLALRLANAIVLPMVLKSAIELNIIDIVSTATSNGLGISPVEIAAQIPTKNPDAPVLLDRMLRLLASYDILNCTKENGRDERLYSARSICKFLTRNDSNEGSSVSPLFLLHHDEVFMKTWYHFNEAILEGGIPFNKTYGMTVFEYQGTDQRFNKVFNEAMSNHTSLIVKKIIKVYNGFDGVKVLVDVGGGIGVTLRIITSKYPHIKGINFDLSHVSADAPSFPGVEHVVGDMFVSVPKGDAISMKWILHDWSDDYCLKLLKNCYEALPSKGKVIVVESILPLVAENAVSSHIVYKQDLFMFAQTPGGKERTQKDYETLAIKSGFSSCKVVCCAYNSWVMEFHKA
>rna-XM_037641599.1
MSLAENHIDEEACLNAMIFSSSHVFPFVLHTAIELNLFGIIAKAGPGAFVSASEIASQLPTTNPDAPSMLDRMLHLFASHSLLSYSSRTLKDGSIQKLYGLTPACKFFIGSVEEGNISSFSYLSYHRATVEVWLNMKDAILEGGNLFKKVHGMSVFEYMNRDPEFNNIFNQAMAGLSSVIMSGILAKYKGFEGLTSLVDVGGGTGRTLHMIISKYPSIKGINYDLPHVIQSAPPYAGIQHVGGNMFTGVPKGDAIMIKETCHNWSDDNVVRVLKNIYEVLPENGKLIILNALLPEEPETSKASQYVSRTDNLMLTQPGGKERTAREFAALTKAAGFTNFRVASVADGICAVMESYK
>rna-XM_037641598.1
MSLAENQIDEEACLNAMIFSSSHVFPFVLHTAIELNLFGIIAKAGPGAFVSASEIASQLPTTNPDAPSMLDRMLHLFASHSLLSYSSRTLKDGSVQKLYGLTPACKFFIGSVEEGNISSLSSLSYLRATVEVWLNMKDAILEGGNLFKKVHGMSIFEYMNRDPEFNTIFNQAMAGLSSVIMNGILAKYKGFEGLTSLVDVGGGTGRTLNMIISKYPSIKGINYDLPHVIQSAPPYTGIQHIGGNMLTCVPKGDAIMIKDTCHNWRDDDVVRVLKNIYEVLPENGKLVILNALLPEEPETSKASQYVSRLDNTMLTQPCGKERTAREFEALTKAAGFTNFRVACVAHGIWAVMESYK
>rna-XM_037641600.1
MIISKYPSIKGINYDLPHVIQSAPPYTGIQHVGGNMFTGIPKGDAIMIKDTCHNWSDDNVVRLLKNIYEVLPENGKLIILNALLPEEPETSKASQYVSRLDNVMLAQPGGKERTAREFEALTEAAGFTNFLVACVAHGIWAVMESYK
>rna-XM_012215526.3
MDSNSINEINEEDEAHLNAMLFSASHIFPMVFRAAIQLNIFGIIAKAGPNAYLSATDIAFHLPTQNPEAPSMLDRMLLLFASHSLLSQSKRTLEDGQVETLYGLTPTSKFFVPCSEEEGGSLAPLSALSTHKVAMEVWLNLKDAILEGGSMFKRVHGMSLFEYMNEDQAFNKIFNDAMAGLSPLIMNAIFQRYKGFEGLNSLVDVGGGTGKVLNMIISKYPSIKGINYDLPHVTLTAPPYPGIQHIGGNMLTSVPQGDAVMIKDTCHNWSDENVIKVLKNVYEVLPKNGKLIIINAILPEEPDTTKASQYVLSLNNTMLMQPGGKERTAKQFESFTKAAGFSNFNVACVARGIWAVMESCK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University