Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Jacaranda mimosifolia
Species name
Jacaranda mimosifolia is a species of eudicot in the family Bignoniaceae (trumpet creeper family).
Species info
Gene sequence info
Jacaranda_mimosifolia.COMT.fa
Download
>Jmimo01049.t1
MDNQSEEEACLFAMQLVSGSVLPMVLKSAIELDLLELIKKAGPGASASELAAQLPTNNPDAASVIDRILRLLAAHSVLNCSLKTLPDGGVERRYSLAPVCKFLTRNEDGVSVAPIAILVQDRISMDSWYHLKDAVLEGGIPFNRTYGMGTFEYMATDMRFSRIFNQAMCESSIIFMIRILEMYKGFEGLKSLVELEQHLE*
>Jmimo01050.t1
MDNQSEEEACLFAMQLVSGGVLPMVLKSAIELDLLELIKKAGPGASASASELAAQLPTTNNPDAASMIDRILRLLAAHSILNCSLKMLADGGVQRRYSLAPVCKFLTRNEDGVSVAPISIMIQDRVLMESWYHLKDAVLEGGISFNKAYGLSAFEYSAIDLRFNRIFNQAMCEPSTIIMKKILEVYKGFEGLKSLVDVGGGIGATLKMIISKYPSIKGINFDLPHVIQDAPSYPGVEHISGDMFVSVPKADAIFMKWICHDWSDAHCQKLLKNCYAALPENGKVIVAETILTEVPNSGLASKMAAQTDVIMLAYLDGKERTENEFEALAKQAGFKQFIKVCCIFNISIMEFHK*
>Jmimo01051.t1
MQLVSGAVLPMVLKSAIELDLLELIKKAGPEASASELAAQHPANNPDAASVIDRILRLLAAHSVLNCSLKTLPDRGVERRYSLAPVCKFLTSNEDGVSVAPIAILVQDRVSMEFCYRLAPENPLLAAYDDGAKVLFGYGSKIPSPTMNGGLITNKCNFSSIFLAGDSAGGNIPYNVALRLKQPSELIKGLILIQPFFGGESRTHSEKYTAQPRRSALTLAAGVAFWSQPRPPVVQSGGGGGSDGRAAAFADYGMRVEDGYIKR*
>Jmimo01054.t1
MPEAPDTGLDTMNIVHADVRMLAHFSGGKERTEEELQALTKGAGFKDFHKVCCAQHSWIMELYK*
>Jmimo01055.t1
MDYSGEEAFSFAMQLAGASILPMVLKCAIELDLFELIKKAGPAGDFVSPAELAAQLPTTNPTAHIMLDRLLRLLTSCSILNCSLRKLPLDEE*
>Jmimo01056.t1
MQLASGAVLPMVLKSAIELDLLELIKKAGPGTSASASELTARLPTNNPGAVSTVDRILRLLAAHSVLNCSLKTLPDGGATPWRWCASS*
>Jmimo01057.t1
MGSAAENRAKITSPVDNQSEEEACLFAMQLASGSVLPMVLKSAIELDLLELIKKAGPEASASELAALLPTNNPEAASMIDRILRLLATYSVLDCSLKTLPDGGVERRFSLAPVCKFLTKNEGGVSVAPLSIMVQDKVLMEPWYHLKDAVLEGGIPFNRVYGMNAFEYPAIDSRFNRIFNQAMYEQSTIFMKKILEIYKGFEGLKSLVDVGGGIGASLKLIISKHPSIKGINFDLPHVIQDAPSYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDAHCQKILKNCYEALPENGKIIIAEAILPEDPNSGLASMRAGISDVIMLAYNPGGKERTEREFQALAKQAGFKELIKICCAFNIWITEFHK*
>Jmimo01058.t1
MDYSGEDACSLALQLAGASILPMVLRCAIELDLFELIKKAGPAGAFVSPAELAAQLPTTNPTAHKMLDRLLRLLTSCSILNCSLRKLPDGGAERLYSLAPVCEFLTKNDDGVSLAPLVLMNQDKVLLESWYCLKDAVLEGGIPFNKAHGMSAFEYLAIDQRFNRLFNQGMSNYSTIVTKKILEKYNGFEGLNSLVDVGGGIGATLNMIISKYPSITDINFDLPHVIEDAPSYLGAEHVGGNMFVSVPKGDAIFMKNCYEALPQNGKVILSEYIMPEAPDTGLDTMNIVHADVRMLAHFSGGKERTEEELQALTKGAGFKDFHKVCCAQNSWIMELYK*
>Jmimo01061.t1
MDYSGEDACSFALQLAGASILPMVLRCAIELDLFELIKKAGPAGAFVSPAELATQLPTTNPTAHIMLDRLLRLLTSCSILNCSLRKLPNGGAERLYSLAPVCEFLTKNDDGVSMAPLVLMNQDKVLMESWYRLKDAVLEGGIPFNKAHGMSAFEYLGTDPRGNTQYDHF*
>Jmimo01065.t1
MDHPEEEEEEEIFLLARQLATASVLPMVLKSAVELDLLELIKKAGPGAFVSPAELAAQLPTTNPEAPVTLDRILRLLASYSVLNCRVRNLAGGSVERLYSLAPVCKFLTKNDDGVSLAPFLLMSQDKVPMECWYHLKNAVLDGGIPFNKAYGMTAFEYHGKDPRFNKIFNEGMSNNSTIIMKKILETYNGFEGLNSLVDVGGGIGTTLNMIISKYPSIKGINFDLPHVTKDAPSYPGVKHVGGDMFVGVPQGDAIFMKSICHDWSDEKCLKILKNCCEALPQNGKVILAEYIMPEAPDTSLATQNVTHVDIAMLANNLGGKERTEREFHSLAKEAGFREFRKVCWARNSWIMELCK*
>Jmimo05866.t1
MLFYFCCELTNPVMLAWLYGLSKLVLANGGSAFQAANGKDFLQHIVLLRGLVDAGGGKRMMLHALVKAYPGILWINLDLPHVVKVEHMGGNFFESMPNVDVVLIKSRCYLHRKNGYLESVVDEGTLSGAFRDNIRIFLQNFAEIEEYTVNDMPVWCTPLVSENEGVFPLYTAEETVEISPDPFCCYCVSSGWGHHFVCKRKYHFIIPRKEGWSTPLNENFTCTTHALYGLIHCNGYGHLIYIDGLRNNSRFFNADDSMEFWDRLCAALKARSISTTMLEKEMTELTLIHGAAFGNSWFEKWGYKYSGKIAEQKYDAAIGFLNSLGLDKIVSDVKNKGDVKMVKERIEMYRKLSENPLVTVGDLLKFMLAIESRIPKVRSNGCKFESETGESPMEFETFIDSMTKDCRWSAKRLENVLSVVVDLLKKQKANNVERECSMSRQELRDEARKSIGDTGLIDFVLKSIKCFTVDNKIIRRAMDPFSRLAQFTIHGISPGSGTWLGLNLSRDISCLYAHVLLLYPETEFVLHNNQFVKHWPIKREIVNQSMELTCKVLPSFSELETELTRPLSPGEVVVVEPWTTIQDLKMVVQCALRDTYCVMNEFEVSQIGGLRKIEDKEVLYSALEPGVQVWVRGSGLDLSTWLRYEDGPEGNHDVR*
>Jmimo05982.t1
MEGGLPFNRAYGMNASEYIVKIPNYLQLFKSMSNYNSMFMEKILEVYKGFEGLKSIVDVGGGDGSILNTIVDKYLTIRGFNFDVAQVIERNAAYLGIEHVAGDMFMSIPKGDAIFLRVSYDDEHCMRILKNCYKALPDHGKVMVVELVVREAPENTVDVRSKLQFDLIMMNMNPGGKERTEGEFKTLARAIGFSSIKVECSVYNFLLVEFYK*
>Jmimo17782.t1
MGSTSKNLGNSSIDSSEEEACLFAMQLASASVLPMVLKSAIELDLLELIKKAGPGAFVSTAELASQLPTTNPEAHIMLDRILRLLASYSVLNCSLKTLPDGGVERLYGLAPVCNFLTKNQDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEFHGTDSRFNKVFNSGMSNNSTIIMKKILETYHGFEGLNTVVDIGGGTGATLNMIISKHPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHYLKFLKNCYEALPENGKVILAECILPEAPDIGLATKNVIHFDVIMLAHYPGGKERTEKEFQALAKGAGFKEFHKVCCAYNSWIMELGK*
>Jmimo20635.t1
MYLTCKIAAGIERDAGDLLISITKGTSIFIKSCGDNKHCVKILKSCCYEMLPADGT*
>Jmimo25440.t1
MLAPWHKLTSPALANGAPAFEAAHVCVAPSCDGIEHVKGNMFEMVPKADAVFLKWVLHDWSDEKRIQILTKCREAIPKNIGKVIIAEVILDEGEEKYSDVRLAHGSMVMLAHTEIGKERTIKEWEYVVYGAGFTKYTVKHIPSAIISVIEAYP*
>Jmimo25441.t1
MAKCREVIPKDTGKVIIGEAVVDEGEQEDKYSDVRLALDMVMLAHTEKGKERTIEEWEYVVYMELASLGTLSNMFQVPLYLLLRPIHD*
MDNQSEEEACLFAMQLVSGSVLPMVLKSAIELDLLELIKKAGPGASASELAAQLPTNNPDAASVIDRILRLLAAHSVLNCSLKTLPDGGVERRYSLAPVCKFLTRNEDGVSVAPIAILVQDRISMDSWYHLKDAVLEGGIPFNRTYGMGTFEYMATDMRFSRIFNQAMCESSIIFMIRILEMYKGFEGLKSLVELEQHLE*
>Jmimo01050.t1
MDNQSEEEACLFAMQLVSGGVLPMVLKSAIELDLLELIKKAGPGASASASELAAQLPTTNNPDAASMIDRILRLLAAHSILNCSLKMLADGGVQRRYSLAPVCKFLTRNEDGVSVAPISIMIQDRVLMESWYHLKDAVLEGGISFNKAYGLSAFEYSAIDLRFNRIFNQAMCEPSTIIMKKILEVYKGFEGLKSLVDVGGGIGATLKMIISKYPSIKGINFDLPHVIQDAPSYPGVEHISGDMFVSVPKADAIFMKWICHDWSDAHCQKLLKNCYAALPENGKVIVAETILTEVPNSGLASKMAAQTDVIMLAYLDGKERTENEFEALAKQAGFKQFIKVCCIFNISIMEFHK*
>Jmimo01051.t1
MQLVSGAVLPMVLKSAIELDLLELIKKAGPEASASELAAQHPANNPDAASVIDRILRLLAAHSVLNCSLKTLPDRGVERRYSLAPVCKFLTSNEDGVSVAPIAILVQDRVSMEFCYRLAPENPLLAAYDDGAKVLFGYGSKIPSPTMNGGLITNKCNFSSIFLAGDSAGGNIPYNVALRLKQPSELIKGLILIQPFFGGESRTHSEKYTAQPRRSALTLAAGVAFWSQPRPPVVQSGGGGGSDGRAAAFADYGMRVEDGYIKR*
>Jmimo01054.t1
MPEAPDTGLDTMNIVHADVRMLAHFSGGKERTEEELQALTKGAGFKDFHKVCCAQHSWIMELYK*
>Jmimo01055.t1
MDYSGEEAFSFAMQLAGASILPMVLKCAIELDLFELIKKAGPAGDFVSPAELAAQLPTTNPTAHIMLDRLLRLLTSCSILNCSLRKLPLDEE*
>Jmimo01056.t1
MQLASGAVLPMVLKSAIELDLLELIKKAGPGTSASASELTARLPTNNPGAVSTVDRILRLLAAHSVLNCSLKTLPDGGATPWRWCASS*
>Jmimo01057.t1
MGSAAENRAKITSPVDNQSEEEACLFAMQLASGSVLPMVLKSAIELDLLELIKKAGPEASASELAALLPTNNPEAASMIDRILRLLATYSVLDCSLKTLPDGGVERRFSLAPVCKFLTKNEGGVSVAPLSIMVQDKVLMEPWYHLKDAVLEGGIPFNRVYGMNAFEYPAIDSRFNRIFNQAMYEQSTIFMKKILEIYKGFEGLKSLVDVGGGIGASLKLIISKHPSIKGINFDLPHVIQDAPSYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDAHCQKILKNCYEALPENGKIIIAEAILPEDPNSGLASMRAGISDVIMLAYNPGGKERTEREFQALAKQAGFKELIKICCAFNIWITEFHK*
>Jmimo01058.t1
MDYSGEDACSLALQLAGASILPMVLRCAIELDLFELIKKAGPAGAFVSPAELAAQLPTTNPTAHKMLDRLLRLLTSCSILNCSLRKLPDGGAERLYSLAPVCEFLTKNDDGVSLAPLVLMNQDKVLLESWYCLKDAVLEGGIPFNKAHGMSAFEYLAIDQRFNRLFNQGMSNYSTIVTKKILEKYNGFEGLNSLVDVGGGIGATLNMIISKYPSITDINFDLPHVIEDAPSYLGAEHVGGNMFVSVPKGDAIFMKNCYEALPQNGKVILSEYIMPEAPDTGLDTMNIVHADVRMLAHFSGGKERTEEELQALTKGAGFKDFHKVCCAQNSWIMELYK*
>Jmimo01061.t1
MDYSGEDACSFALQLAGASILPMVLRCAIELDLFELIKKAGPAGAFVSPAELATQLPTTNPTAHIMLDRLLRLLTSCSILNCSLRKLPNGGAERLYSLAPVCEFLTKNDDGVSMAPLVLMNQDKVLMESWYRLKDAVLEGGIPFNKAHGMSAFEYLGTDPRGNTQYDHF*
>Jmimo01065.t1
MDHPEEEEEEEIFLLARQLATASVLPMVLKSAVELDLLELIKKAGPGAFVSPAELAAQLPTTNPEAPVTLDRILRLLASYSVLNCRVRNLAGGSVERLYSLAPVCKFLTKNDDGVSLAPFLLMSQDKVPMECWYHLKNAVLDGGIPFNKAYGMTAFEYHGKDPRFNKIFNEGMSNNSTIIMKKILETYNGFEGLNSLVDVGGGIGTTLNMIISKYPSIKGINFDLPHVTKDAPSYPGVKHVGGDMFVGVPQGDAIFMKSICHDWSDEKCLKILKNCCEALPQNGKVILAEYIMPEAPDTSLATQNVTHVDIAMLANNLGGKERTEREFHSLAKEAGFREFRKVCWARNSWIMELCK*
>Jmimo05866.t1
MLFYFCCELTNPVMLAWLYGLSKLVLANGGSAFQAANGKDFLQHIVLLRGLVDAGGGKRMMLHALVKAYPGILWINLDLPHVVKVEHMGGNFFESMPNVDVVLIKSRCYLHRKNGYLESVVDEGTLSGAFRDNIRIFLQNFAEIEEYTVNDMPVWCTPLVSENEGVFPLYTAEETVEISPDPFCCYCVSSGWGHHFVCKRKYHFIIPRKEGWSTPLNENFTCTTHALYGLIHCNGYGHLIYIDGLRNNSRFFNADDSMEFWDRLCAALKARSISTTMLEKEMTELTLIHGAAFGNSWFEKWGYKYSGKIAEQKYDAAIGFLNSLGLDKIVSDVKNKGDVKMVKERIEMYRKLSENPLVTVGDLLKFMLAIESRIPKVRSNGCKFESETGESPMEFETFIDSMTKDCRWSAKRLENVLSVVVDLLKKQKANNVERECSMSRQELRDEARKSIGDTGLIDFVLKSIKCFTVDNKIIRRAMDPFSRLAQFTIHGISPGSGTWLGLNLSRDISCLYAHVLLLYPETEFVLHNNQFVKHWPIKREIVNQSMELTCKVLPSFSELETELTRPLSPGEVVVVEPWTTIQDLKMVVQCALRDTYCVMNEFEVSQIGGLRKIEDKEVLYSALEPGVQVWVRGSGLDLSTWLRYEDGPEGNHDVR*
>Jmimo05982.t1
MEGGLPFNRAYGMNASEYIVKIPNYLQLFKSMSNYNSMFMEKILEVYKGFEGLKSIVDVGGGDGSILNTIVDKYLTIRGFNFDVAQVIERNAAYLGIEHVAGDMFMSIPKGDAIFLRVSYDDEHCMRILKNCYKALPDHGKVMVVELVVREAPENTVDVRSKLQFDLIMMNMNPGGKERTEGEFKTLARAIGFSSIKVECSVYNFLLVEFYK*
>Jmimo17782.t1
MGSTSKNLGNSSIDSSEEEACLFAMQLASASVLPMVLKSAIELDLLELIKKAGPGAFVSTAELASQLPTTNPEAHIMLDRILRLLASYSVLNCSLKTLPDGGVERLYGLAPVCNFLTKNQDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEFHGTDSRFNKVFNSGMSNNSTIIMKKILETYHGFEGLNTVVDIGGGTGATLNMIISKHPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHYLKFLKNCYEALPENGKVILAECILPEAPDIGLATKNVIHFDVIMLAHYPGGKERTEKEFQALAKGAGFKEFHKVCCAYNSWIMELGK*
>Jmimo20635.t1
MYLTCKIAAGIERDAGDLLISITKGTSIFIKSCGDNKHCVKILKSCCYEMLPADGT*
>Jmimo25440.t1
MLAPWHKLTSPALANGAPAFEAAHVCVAPSCDGIEHVKGNMFEMVPKADAVFLKWVLHDWSDEKRIQILTKCREAIPKNIGKVIIAEVILDEGEEKYSDVRLAHGSMVMLAHTEIGKERTIKEWEYVVYGAGFTKYTVKHIPSAIISVIEAYP*
>Jmimo25441.t1
MAKCREVIPKDTGKVIIGEAVVDEGEQEDKYSDVRLALDMVMLAHTEKGKERTIEEWEYVVYMELASLGTLSNMFQVPLYLLLRPIHD*
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University