Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Ipomoea nil
Species name
Japanese morning glory (Ipomoea nil) is a species of eudicot in the family Convolvulaceae (morning-glory family).
Species info
Gene sequence info
Ipomoea_nil.CHS.fa
Download
>rna-XM_019326011.1
MVTVEEVRKAQRAEGPATILAIGTATPANCVDQSTYPDYYFRITNSDHMTDLKQKFQRMCDKSMITKRYMHLTEEILKENPSFCEYMAPSLDARQDIVVVEVPKLGKEAAQSAIKEWGQPKSKITHVIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKAARVLVVCSEITVVTFRGPNETHLDSLVGQALFGDGAAAIIVGSDPTPAEKPLFQLVSAAQTLAPDSCGAIDGHLREVGLTFHLLKDVPSIVSNNIEKCLSEAFNPLGISDWNSIFWIAHPGGPAILDQVEDKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKASSNDGLGTTGEGLEWGVLFGFGPGLTIETVVLHSVPA
>rna-XM_019339955.1
MSTTITVLTDTWSHRAKRLEGDAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLEHKEKFRRICNKSKIMKRHLVLTEELLKKHPNLCTYNEASLNTRQDILVSGVPKLGKEAAMKAIKEWGRPISEITHLVFCTTSGVDMPGADFQLTKLLGLNSSVKRLMMYQQGCNAGAAMLRLAKDLAENNKGARVLVVCSEITINIFRGPSLEQDDNLLAQCLFGDGAAAMIVAADPRPGLETPLFELVSSAQTIVPNTDSHLKLHLREMGLTFHCSKAVPSVLAENVEDCLVKAFEPYGISDWNSIFWVFHPGGNAIVDRVEERLGLGPEKFRASRDVLSEYGNLTSACVLFILDEMRKKSKKDEQMTTGEGLEWGVVFGFGPGLTIDTIIIRSVPIN
>rna-XM_019339957.1
MSTILTNTWTRREKRIEGHAKILAIGTAIPANWVDQTTYPDFYFRITNSEHLLEHKEKFRRICNKSKIRKRHLVITEELLKKNPNLCTYNEASLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTSSGVDMPGADFQLAKLLGLSSSVNRLMMYQQGCNAGAAMLRLAKDLAENNKGGRVLVVCSEVMLNVFRGPSLEQEDNLLAQCLFGDGSAAVIVGTEPRPGLETPLFELVSAAQTTIPDTDSHLKLHLREMGLTFHCSKAVPSLITQNVEDCLVKAFEPFGISDWNSIFWILHPGGIAILDRVEEKLGLEPEKLRASKDVLSEYGNLTSACVLFILDEMRKKSKKDEEMTTGEGLEWGVVFGFGPGLTIDTVVIRSVPTN
>rna-XM_019339958.1
MSTTVTVLTDTCRSRRAKRFEGDAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLEHKEKFRRICNKSKIKKRHLVLKKNPNLCTYNEASLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTSSGVDMPGADFQLAKLLGLSSSVKRLMMYQQGCNAGAAMLRLAKDLAENNKGGRVLVVWSEVMLNVFRGPSLEQEDNLLAQCLFGDGSAAVIVGTEPRPGLETPLFELVSAAQTTIPDTDSHLKLHLREMGLTFHCSKAVPSLITQNVEDCLVKAFEPFGISDWNSIFWILHPGGIAILDRVEEKLGLEPEKLRASKDVLSEYGNLTSACVLFILDEMRKKSKKDEQMTTGEGLEWGVVFVVCP
>rna-XM_019305433.1
MMSNLNGKDNVSTQNYYRSSPTSRRRLPTQGKATILALGKAFPSQLVPQDCLVEGYIRDTKCDDLAIKEKLERLCKTTTVKTRYTVMCKDVLDKYPELATEGSPTIAQRLEVANPAVIAMAKEASLACIKDWGRPVEEITHVVYVSSSEIRLPGGDLYLAAELGLKSDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGANPRESLENPFMELSFAAQQFLPGTQSVIDGRISEEGINFKLGRDLPEKIENNIEDFCKKLIGKANNNNNNLTYNELFWAVHPGGPAILNRLERTLGLRSEKLDCSRRALMDFGNVSSNTIFYVLEYMRDELMMKRKQGKEEEEEGGLEWGLALAFGPGITFEGILLRNLQ
>rna-XM_019310063.1
MVTVEEVRKAQRAQGPATIMAIGTSTPQNCVDQSTYPDYYFRITNSEHLVELKEKFKRMCEKSMIKKRYMYLTEEILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLQPSVKRFMMYQQGCFAGGTVIRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAALIIGSDPDPDLERPLFQLVSAAQTILPDSGGAIDGHLREVGLTFHLLKDVPGLISKHIEKSLNEAFQPLGIHDWNSLFWIAHPGGPAILDQVEEKLELKPEKLRATRHVLSEYGNMSSACVLFILDEMRKASSKEGLNTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
MVTVEEVRKAQRAEGPATILAIGTATPANCVDQSTYPDYYFRITNSDHMTDLKQKFQRMCDKSMITKRYMHLTEEILKENPSFCEYMAPSLDARQDIVVVEVPKLGKEAAQSAIKEWGQPKSKITHVIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKAARVLVVCSEITVVTFRGPNETHLDSLVGQALFGDGAAAIIVGSDPTPAEKPLFQLVSAAQTLAPDSCGAIDGHLREVGLTFHLLKDVPSIVSNNIEKCLSEAFNPLGISDWNSIFWIAHPGGPAILDQVEDKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKASSNDGLGTTGEGLEWGVLFGFGPGLTIETVVLHSVPA
>rna-XM_019339955.1
MSTTITVLTDTWSHRAKRLEGDAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLEHKEKFRRICNKSKIMKRHLVLTEELLKKHPNLCTYNEASLNTRQDILVSGVPKLGKEAAMKAIKEWGRPISEITHLVFCTTSGVDMPGADFQLTKLLGLNSSVKRLMMYQQGCNAGAAMLRLAKDLAENNKGARVLVVCSEITINIFRGPSLEQDDNLLAQCLFGDGAAAMIVAADPRPGLETPLFELVSSAQTIVPNTDSHLKLHLREMGLTFHCSKAVPSVLAENVEDCLVKAFEPYGISDWNSIFWVFHPGGNAIVDRVEERLGLGPEKFRASRDVLSEYGNLTSACVLFILDEMRKKSKKDEQMTTGEGLEWGVVFGFGPGLTIDTIIIRSVPIN
>rna-XM_019339957.1
MSTILTNTWTRREKRIEGHAKILAIGTAIPANWVDQTTYPDFYFRITNSEHLLEHKEKFRRICNKSKIRKRHLVITEELLKKNPNLCTYNEASLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTSSGVDMPGADFQLAKLLGLSSSVNRLMMYQQGCNAGAAMLRLAKDLAENNKGGRVLVVCSEVMLNVFRGPSLEQEDNLLAQCLFGDGSAAVIVGTEPRPGLETPLFELVSAAQTTIPDTDSHLKLHLREMGLTFHCSKAVPSLITQNVEDCLVKAFEPFGISDWNSIFWILHPGGIAILDRVEEKLGLEPEKLRASKDVLSEYGNLTSACVLFILDEMRKKSKKDEEMTTGEGLEWGVVFGFGPGLTIDTVVIRSVPTN
>rna-XM_019339958.1
MSTTVTVLTDTCRSRRAKRFEGDAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLEHKEKFRRICNKSKIKKRHLVLKKNPNLCTYNEASLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTSSGVDMPGADFQLAKLLGLSSSVKRLMMYQQGCNAGAAMLRLAKDLAENNKGGRVLVVWSEVMLNVFRGPSLEQEDNLLAQCLFGDGSAAVIVGTEPRPGLETPLFELVSAAQTTIPDTDSHLKLHLREMGLTFHCSKAVPSLITQNVEDCLVKAFEPFGISDWNSIFWILHPGGIAILDRVEEKLGLEPEKLRASKDVLSEYGNLTSACVLFILDEMRKKSKKDEQMTTGEGLEWGVVFVVCP
>rna-XM_019305433.1
MMSNLNGKDNVSTQNYYRSSPTSRRRLPTQGKATILALGKAFPSQLVPQDCLVEGYIRDTKCDDLAIKEKLERLCKTTTVKTRYTVMCKDVLDKYPELATEGSPTIAQRLEVANPAVIAMAKEASLACIKDWGRPVEEITHVVYVSSSEIRLPGGDLYLAAELGLKSDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGANPRESLENPFMELSFAAQQFLPGTQSVIDGRISEEGINFKLGRDLPEKIENNIEDFCKKLIGKANNNNNNLTYNELFWAVHPGGPAILNRLERTLGLRSEKLDCSRRALMDFGNVSSNTIFYVLEYMRDELMMKRKQGKEEEEEGGLEWGLALAFGPGITFEGILLRNLQ
>rna-XM_019310063.1
MVTVEEVRKAQRAQGPATIMAIGTSTPQNCVDQSTYPDYYFRITNSEHLVELKEKFKRMCEKSMIKKRYMYLTEEILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLQPSVKRFMMYQQGCFAGGTVIRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAALIIGSDPDPDLERPLFQLVSAAQTILPDSGGAIDGHLREVGLTFHLLKDVPGLISKHIEKSLNEAFQPLGIHDWNSLFWIAHPGGPAILDQVEEKLELKPEKLRATRHVLSEYGNMSSACVLFILDEMRKASSKEGLNTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University