Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Ipomoea nil
Species name
Japanese morning glory (Ipomoea nil) is a species of eudicot in the family Convolvulaceae (morning-glory family).
Species info
Gene sequence info
Ipomoea_nil.4CL.fa
Download
>rna-XM_019333290.1
METKSVQGDVIFRSKLPDIYIPKHLPLHSYCFENISEFKERPCLIDGATEKIYTYAEVELTSRRVAAGLDKQGIKQGDTIMILLPNSPEFVFAFLGASFRGALSTMANPLFTAAEVVKQAKASNAKLIVTQACYVERVKDYARDHGVKVACIDSAPEGCLHFSELAGADERDMPEVEIEAEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGVNPNLYFHKDDVMLCVLPLFHIYSLNSVLLCGLRAGSAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVNPDTGSSLPRNKSGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDEELFIVDRLKELIKYKGYQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVKSKGSVITEDDIKAFVSKQVIFYKRIKRVFFVDAVPKSPSGKILRKELRARLADGVPA
>rna-XM_019333436.1
MEKSGYGRDGIYRSLRPPIVLPRDPNLSMVSFLFRNISQYPDQPAIHDADTGRTLTFSQLKSQVSRVAHGLKHQLGVRKNDVVLIFSPNSIDFPLCFLGAIAAGAIATTVNPMYTVPELSKQIKDCSPKLIVTVPQLLDKVKGFNLPVLVLGQEKTSISGLTYFTDLVKNSGSLNFDTISINQSDTAALLYSSGTTGLSKGVILTHRNFIATSQMVAADQDAAGEPQNTFLCFLPLFHVFGLSIILYSQLARGNSVVTMGKFDLEMILKTVDKYRVTHMWVVPPIILALAKNSVVKKYNLTSLRQIGSGAAPLGKELMEECAKNFPQATVIQGYGMTETCGVVCIENTRIGPRHSGSAGLLVSAVEAQIVSVDKLQHLPPGQLGEIWVRGPNMMQGYYKNPQATKLTIDKQGWVHTGDLGYFNKDGMLYVVDRIKELIKYKGYQVAPAELEGLLVSHPEIQDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVKKFIAGQVAPYKRLRKVTFINSVPKSASGKILRRELIEKVRAKL
>rna-XM_019339998.1
MGSNAGQTSTKQDDEHIFRSKYPPVQVPDDMTLPDFVLHNVELYADKVAIVDATTGKEYTYGQVARDVRRFAKALRSLGLRKGRLVVVVLPNVAEYPIIALGIMAAGGVLSGANPTSHASELEKQVQVADAKLIVVDAPTYYKVKDLGLPVIVVDEERVQGTINWGELLEAADRASNDFAFSEDEVVKQNDLCALPFSSGTTGMSKGVMLTHRNLVANLCSSLFSVGPDMIGQLIILGLIPFFHIYGLVGICCATMRNKGKVVAMRRYELRAFLDALITHEVNFAPIVPPIILGLVKNPIVDEFDLSKLKLKSIMTAAAPLAPEILNEFQKKFPGIQVQEAYGMTEHSCITLTHGDPRKGHGIAKKNSVGFILPNLEVKFIDPDSGLSLPRNTPGELCVRSQCVMKGYYNNEYETALTIDKDGWLHTGDIGYIDEDGDIFIVDRIKELIKFKGFQVAPAELEATLLSHPSVEDAAVVGLPDEEAGEVPAACVVLSAGAKDSEEDIMNYVASSVAHYKRVRVLHFVDAIPKSHSGKIMRRVIKDKMVQNLTTASSHDVRKKLLA
>rna-XM_019343484.1
MEKSGYGGDGIYRSLRPPLVLPSDQNLSMVSFLFRNVSQYPDKPALVDANSGRTLTFSQLKSQVSKVSHGLMHQLGVRNNDVVLIFSPNSVEFPLCFFGIVAIGAVATTANPSYTVSELSKQVKDCSPKLIVTVPFLLDKVKGFNLPVLLLRPENANLDRSKSGAGITFFHDLVRNSGSLNLGRVSIKQSDEAALLYSSGTTGISKGVVLTHRNFIATAKMAASDQDAAGEIHNVFLCVLPLFHVFGLSVITYSQLARGNAIVIMEKFDLNMTLKNVEKYEVTHLRVVPPILLAMAKSSLVKKYNLKSLRLIGSGAAPLGKELMEECAKNFPHAIVTQGYGMTETCGVISSENPNIGRRHTGSSGMLQPGIEAQVVSVSELKPLPPGQIGEVWVRGPNVMLGYYNNPQATSLVIDKQGWVHTGDLGYFDEEGLLYIVDRIKELIKYKGFQVAPAELESLLISHPEIVDAVVIPFPDAEAGEIPAAYVVRSLNSSLTEEDVQKFIADQVAPFKRLRRVTFIKSVPKSASGKILRRLLIEKARSRI
>rna-XM_019344192.1
MLSVETQKPELEVADSGKTQAQSSQIHIFRSRLPDIPIPNQIPLHTYCFQNLAEYRDRTCLIVGSTGKTYSFAETHLICRKVASGLGKLGVKKGDVIMTLLQNCPEFVFSFMGASMIGAVTTTANPFYTKSEIFKQMSASKAKVIITQSMYVEKLKDSGEEYPKLGEDFSVVTVDDPPENCLHFSVLSEADEEDIPATVDIAPDDAVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIFSLNSVLLCSLRAGAAVLLMQKFEIKALLELVKKHRVSVAAVVPPLVLALAKNPIVDSYDLSSIRVVLSGAAPLGKELEEALLQRVPQAIFGQGYGMTEAGPVLSMCPAFAKQPLPAKSGSCGSVVRNAELMVVDPETGCSLGRNKPGEICIRGSQIMKEYLNDPAATARTIDVDGWLHTGDIGFVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLLSHPMIADAAVVPQKDDAAGEVPVAFVVRSSDGFDLTEEAVKEFIAKQVVFYKKLHKVYFIHAIPKSASGKILRKDLREKLQAPPPSTPQ
>rna-XM_019311818.1
MATKTEQGGGDIIFRSKLPDIYISNHLPLHSYCFQNISVLRDRPCLINGSDDRVYTYAEVELSCRKVAAGLHKAGINHGDTIMILLPNCPEFVFAFLGASYRGAVATMANPLFTPAEVIKQVKASNAKLIVTLACYVDKVREYAWENEIKVFCTDSAPKGCSHFSELSEAEENDMPETEVKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPHLYIHDQDVVLCALPFFHIYSNSILLCGLRVGARILIMNKFDINLFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKELQDTVRAKFPNAKLGQGYGMTEAGSVLAMCLAFAKEPFEIKSGSCGTVVRNAEMRIVDPDTGSSLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPQISDAAVIPMKDEQAGEVPVAFVVKTNGCSLTEDEVKEFVSKQVIFYKRIKKVFFVDSVPKSPSGKILRKNLRARLEAGIPN
METKSVQGDVIFRSKLPDIYIPKHLPLHSYCFENISEFKERPCLIDGATEKIYTYAEVELTSRRVAAGLDKQGIKQGDTIMILLPNSPEFVFAFLGASFRGALSTMANPLFTAAEVVKQAKASNAKLIVTQACYVERVKDYARDHGVKVACIDSAPEGCLHFSELAGADERDMPEVEIEAEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGVNPNLYFHKDDVMLCVLPLFHIYSLNSVLLCGLRAGSAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVNPDTGSSLPRNKSGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDEELFIVDRLKELIKYKGYQVAPAELEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVKSKGSVITEDDIKAFVSKQVIFYKRIKRVFFVDAVPKSPSGKILRKELRARLADGVPA
>rna-XM_019333436.1
MEKSGYGRDGIYRSLRPPIVLPRDPNLSMVSFLFRNISQYPDQPAIHDADTGRTLTFSQLKSQVSRVAHGLKHQLGVRKNDVVLIFSPNSIDFPLCFLGAIAAGAIATTVNPMYTVPELSKQIKDCSPKLIVTVPQLLDKVKGFNLPVLVLGQEKTSISGLTYFTDLVKNSGSLNFDTISINQSDTAALLYSSGTTGLSKGVILTHRNFIATSQMVAADQDAAGEPQNTFLCFLPLFHVFGLSIILYSQLARGNSVVTMGKFDLEMILKTVDKYRVTHMWVVPPIILALAKNSVVKKYNLTSLRQIGSGAAPLGKELMEECAKNFPQATVIQGYGMTETCGVVCIENTRIGPRHSGSAGLLVSAVEAQIVSVDKLQHLPPGQLGEIWVRGPNMMQGYYKNPQATKLTIDKQGWVHTGDLGYFNKDGMLYVVDRIKELIKYKGYQVAPAELEGLLVSHPEIQDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVKKFIAGQVAPYKRLRKVTFINSVPKSASGKILRRELIEKVRAKL
>rna-XM_019339998.1
MGSNAGQTSTKQDDEHIFRSKYPPVQVPDDMTLPDFVLHNVELYADKVAIVDATTGKEYTYGQVARDVRRFAKALRSLGLRKGRLVVVVLPNVAEYPIIALGIMAAGGVLSGANPTSHASELEKQVQVADAKLIVVDAPTYYKVKDLGLPVIVVDEERVQGTINWGELLEAADRASNDFAFSEDEVVKQNDLCALPFSSGTTGMSKGVMLTHRNLVANLCSSLFSVGPDMIGQLIILGLIPFFHIYGLVGICCATMRNKGKVVAMRRYELRAFLDALITHEVNFAPIVPPIILGLVKNPIVDEFDLSKLKLKSIMTAAAPLAPEILNEFQKKFPGIQVQEAYGMTEHSCITLTHGDPRKGHGIAKKNSVGFILPNLEVKFIDPDSGLSLPRNTPGELCVRSQCVMKGYYNNEYETALTIDKDGWLHTGDIGYIDEDGDIFIVDRIKELIKFKGFQVAPAELEATLLSHPSVEDAAVVGLPDEEAGEVPAACVVLSAGAKDSEEDIMNYVASSVAHYKRVRVLHFVDAIPKSHSGKIMRRVIKDKMVQNLTTASSHDVRKKLLA
>rna-XM_019343484.1
MEKSGYGGDGIYRSLRPPLVLPSDQNLSMVSFLFRNVSQYPDKPALVDANSGRTLTFSQLKSQVSKVSHGLMHQLGVRNNDVVLIFSPNSVEFPLCFFGIVAIGAVATTANPSYTVSELSKQVKDCSPKLIVTVPFLLDKVKGFNLPVLLLRPENANLDRSKSGAGITFFHDLVRNSGSLNLGRVSIKQSDEAALLYSSGTTGISKGVVLTHRNFIATAKMAASDQDAAGEIHNVFLCVLPLFHVFGLSVITYSQLARGNAIVIMEKFDLNMTLKNVEKYEVTHLRVVPPILLAMAKSSLVKKYNLKSLRLIGSGAAPLGKELMEECAKNFPHAIVTQGYGMTETCGVISSENPNIGRRHTGSSGMLQPGIEAQVVSVSELKPLPPGQIGEVWVRGPNVMLGYYNNPQATSLVIDKQGWVHTGDLGYFDEEGLLYIVDRIKELIKYKGFQVAPAELESLLISHPEIVDAVVIPFPDAEAGEIPAAYVVRSLNSSLTEEDVQKFIADQVAPFKRLRRVTFIKSVPKSASGKILRRLLIEKARSRI
>rna-XM_019344192.1
MLSVETQKPELEVADSGKTQAQSSQIHIFRSRLPDIPIPNQIPLHTYCFQNLAEYRDRTCLIVGSTGKTYSFAETHLICRKVASGLGKLGVKKGDVIMTLLQNCPEFVFSFMGASMIGAVTTTANPFYTKSEIFKQMSASKAKVIITQSMYVEKLKDSGEEYPKLGEDFSVVTVDDPPENCLHFSVLSEADEEDIPATVDIAPDDAVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIFSLNSVLLCSLRAGAAVLLMQKFEIKALLELVKKHRVSVAAVVPPLVLALAKNPIVDSYDLSSIRVVLSGAAPLGKELEEALLQRVPQAIFGQGYGMTEAGPVLSMCPAFAKQPLPAKSGSCGSVVRNAELMVVDPETGCSLGRNKPGEICIRGSQIMKEYLNDPAATARTIDVDGWLHTGDIGFVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLLSHPMIADAAVVPQKDDAAGEVPVAFVVRSSDGFDLTEEAVKEFIAKQVVFYKKLHKVYFIHAIPKSASGKILRKDLREKLQAPPPSTPQ
>rna-XM_019311818.1
MATKTEQGGGDIIFRSKLPDIYISNHLPLHSYCFQNISVLRDRPCLINGSDDRVYTYAEVELSCRKVAAGLHKAGINHGDTIMILLPNCPEFVFAFLGASYRGAVATMANPLFTPAEVIKQVKASNAKLIVTLACYVDKVREYAWENEIKVFCTDSAPKGCSHFSELSEAEENDMPETEVKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPHLYIHDQDVVLCALPFFHIYSNSILLCGLRVGARILIMNKFDINLFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKELQDTVRAKFPNAKLGQGYGMTEAGSVLAMCLAFAKEPFEIKSGSCGTVVRNAEMRIVDPDTGSSLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPQISDAAVIPMKDEQAGEVPVAFVVKTNGCSLTEDEVKEFVSKQVIFYKRIKKVFFVDSVPKSPSGKILRKNLRARLEAGIPN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University