Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Iberis amara
Species name
Bitter candytuft (Iberis amara) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Iberis_amara.HIDH.fa
Download
>Ibeam.0013s0002.1.v1.1
MESEIASELLPFCRIYKDGRVERLSGTEIIPSSLDPANDVVSKDVVYSPEHNLSVRLFLPHKTTQLVSGNKLPLLMYIHGGAWIIESPFSTIYHNYLMDVVKSANCLAVSIQYRRAPEDPIPAAYEDSWAAIEWIFSHSNGSGPEDWINKHADFCRVFIAGDSAGANLSHHMAMRAGKEKLNPRIKGIAIVHPAFWGTDPVDEYDVQDMEIRSGIAEVWEKIASPNSLNGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGKDVFVRQGLAYAAKLEKSAWEGTVEVIEEEEEGHVFHLQKPNSEKASKFLEKLVEFIMC
>Ibeam.0156s0015.1.v1.1
MDSEIAFDKFPYYRVYKSGRIERLHGETIVPPSLTPQNGVVSKDTVYSSEKNLSLRIYLPEKVVETGKKLPVLVYFHGGGFIIETAFSPTYHTFLTSAVAAADCIAISVEFPIPIPYEDSWVALKWVFSHISGSGPESWINKHADFSKVFLAGDSAGGNITHHLTIRAKREKLESVILGIILIHPYFWGKTPIDELETRDETRRKMIEGNWGIASPNSKNGADDPLINVVGSESSDLSGLGCGRVFVMVAGDDIFVRQGIGYAEKLKKKSEWEGEVELMETQNEGHVFHLTNPNTDNARKLVKNLAEFINK
>Ibeam.0499s0005.1.v1.1
MDSEIAADYSPLLKIYKSGRIERLMGETTVPPSSLPQNGVVSKDVIYSPEDNLSVRIYLPEKVAETEAKLPLLVYYHGGGFIIETAFSPTYHTFLTAAVSASECIAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGSGSEDLLNKHADFSKVFLAGDSAGANIAHHMTMRAAKEKPSPDLRDSGISGIILVHPYFWSKTPLDEKETTDKTLRSKIEAIWTMASPNSKEGSDDPWLNVVESETSDLSGLGCGRVLVLVAEKDALARQGWGYAAKLEKSGWKGEVELVESEGEEHVFHLTKPDCDKALQAMHKFAAFLKGHN
>Ibeam.0607s0010.1.v1.1
MLMGANTLTHVTSINPNNINIHGPVIDEVEGLIRVYKDGHVERPELIPCVGPSLALELGVDCSDVHIDKLTNVWARLYVPMVTKSLVSFSKFPLLVYFHGGGFCVGSASWSCYHEFLARLSASSRCLIMSVNYRLAPENPLSAAYEDGVNAIQWLKKTRNENVWASLCNFGRIFLAGDSAGGNIAHHVAAKLADAEDRIKPLKIEGTILIQPFFGGEARTESERRVGNNKKSSVLTLASSDAWWRLALPSGANREHPYCKPVKTVARTLVCVAEMDVLMDREMEMCDGNEKLIKRVVYKGVGHAFQILGKSQLAHTTTLEMLCHIDAFIHHYDPSLIS
>Ibeam.1086s0013.1.v1.1
MATISFSHNHHASRGGSNNHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVPPTLHPSAKVTAFDIKLSNDILTRVYIPLTSASPSVSTLPLVIYFHGGGFCVGSVAWSCYHDFLTNLAVKATCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLVKQQISNNRGYNSNWVNKCNLSNVFLAGDSAGANIAYQVAVRITASGRYVNSLNLKGIILIHPFFGGESRTSSEILQQHHSKSTSALTLSASDTYWRLALPRGASRDHPWCNPFVNPENVLIREAKLPTTMVFVAEFDILKDRNLEMCRVMRSHVKRVECVVHGGVGHAFHVLDNSSVSSDRTHDMMCRLHNFINH
>Ibeam.1486s0006.1.v1.1
MDMESSIKKQVSLEVLPWLVVHSDGRLERLVGTEVCPPGLDQETHVLSKDIIIEPKTGLSARIYRPDTVRPGQKLPLVLYFHGGAFLISSAAFPFYHKSVNKLVAKANIIAVSVNYRLAPEHPLPTAYEDSWNAIQMIGSIKEPWINDYADFNRLFLIGDSAGANISHHLAFRDSAVKIKGVGMIHPYFWGTQPMGSEVNDEARKHMVDGWWEFVCPSEKGSDDPWINPFSDGSPELEELGCERVMITVAENDILRERGKMYYERLVKSKWKGKVEMMETKGKDHVFHIFEPDCHEAMEMLQNLALFINQA
>Ibeam.1550s0003.1.v1.1
MLRRITFSSSICLRHLSFRAFRQLPRSYLLSSPTTVGTSGRNPLRPSTLRCVSSHSSSEVAAEHPPFVRIYKNGRVERLSGTEIVPASLTPQNGVVSKDVVYLPEHNLSVRLFLSHKAADNNKLPLLIYIHGGAWIIQSPFSPIYHNFLSEVVKSANCLAMSIQYRRAPEHPIPAAYDDSWSAIQWILSHSVGSGGPEDWINKYADFDKVFLAGDSAGANISHHMAIKAGKEKLNPRIKGTAIVHPAFWGKDPVDEHDVQDREIRNEIARVWEKIASPNSVDGTDDPLFNVVGSGSDFSGMGCDKVLVAVAGKDVFVRQGLAYAKKLKKSGWEGEVEVIEDEDEDHCFHLLNPNSQNAPKFTKKFVEFITG
>Ibeam.1975s0007.1.v1.1
MDSDSEIAYDYSPRFRIYKNGRIQRLLNETFVPPSLNPENGVVSTDAVYSTEKNLSLRIYLPQNAVETDHHKKKRKLTLLVYFHGGGFIMESAFSPVYHTFLTSVVSASDCIAVSVNYRRAPEHPIPIAYEDSWDAIKWVFSHFAGSGPNDWLNENADYSMIFLAGDSAGANIAHHMVIRAGKEISGSGSGYGGLKISGLTLFHPFFLSNTPKEEHEVEGMRYFEGIWKIASPKSEKGVEDPWINVVGSDLSGLGCERVLVMVAGNDVLAKQGWRYAEELEKSGWEGKVEVTETKNEGHVFHLRKPLSDNSRLLLQRFVEFLN
>Ibeam.5413s0003.1.v1.1
MCVSLNISLSMDSEIAFDKFPYYRVYKSGRIERLHGETIVPPSLTPQNGVISKDTVYSSEKNLSLRIYLPEKVVETGKKLPVLVYFHGGGFIIETAFSPTYHTFLTSAVAAADCIAISVDYRRAPEFPIPIPYEDSWVSLKWVFSHISGSGPESWINKHADFSKVFLAGDSAGGNITHHLTIRAKREKLESVIFGIILIHPYFWGKTPIDELETRDETRRKMIEGNWGIASPNSKNGADDPLINVVGSESSDLSGLGCGRVLVMVAGDDNFVRQGIGYAEKLKKKSEWEGEVELMETENEGHVFHLRNPNTDNARKLVKNLAEFINK
>Ibeam.7917s0001.1.v1.1
MDSDSEIAYDYSPRFRIYKNGRIQRLLNETFVPPSLNPENGVVSTDAVYSTEKNLSLRIYLPQTDHHKKKRKLTLLVYFHGGGFIMESAFSPVYHTFLTSVVSASNCIAVSVNYRRAPEHPIPIAYEDSWDAIKWVFSHFAGSGPNDWLNENADYSMIFLAGDSAGANIAHHMVIRAGKEISGSGWGYGGLKISGLTLFHPFFLSNTPKEEHEVEGMRYFEGIWKIASPKSEKGVEDPWINVVGSDLSGLGCERVLVMVAGNDVLAKQGWRYAEELEKSGWEGKVEVTETKEEGHVFHLRKPQSDNYRLLLQRFVEFLN
MESEIASELLPFCRIYKDGRVERLSGTEIIPSSLDPANDVVSKDVVYSPEHNLSVRLFLPHKTTQLVSGNKLPLLMYIHGGAWIIESPFSTIYHNYLMDVVKSANCLAVSIQYRRAPEDPIPAAYEDSWAAIEWIFSHSNGSGPEDWINKHADFCRVFIAGDSAGANLSHHMAMRAGKEKLNPRIKGIAIVHPAFWGTDPVDEYDVQDMEIRSGIAEVWEKIASPNSLNGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGKDVFVRQGLAYAAKLEKSAWEGTVEVIEEEEEGHVFHLQKPNSEKASKFLEKLVEFIMC
>Ibeam.0156s0015.1.v1.1
MDSEIAFDKFPYYRVYKSGRIERLHGETIVPPSLTPQNGVVSKDTVYSSEKNLSLRIYLPEKVVETGKKLPVLVYFHGGGFIIETAFSPTYHTFLTSAVAAADCIAISVEFPIPIPYEDSWVALKWVFSHISGSGPESWINKHADFSKVFLAGDSAGGNITHHLTIRAKREKLESVILGIILIHPYFWGKTPIDELETRDETRRKMIEGNWGIASPNSKNGADDPLINVVGSESSDLSGLGCGRVFVMVAGDDIFVRQGIGYAEKLKKKSEWEGEVELMETQNEGHVFHLTNPNTDNARKLVKNLAEFINK
>Ibeam.0499s0005.1.v1.1
MDSEIAADYSPLLKIYKSGRIERLMGETTVPPSSLPQNGVVSKDVIYSPEDNLSVRIYLPEKVAETEAKLPLLVYYHGGGFIIETAFSPTYHTFLTAAVSASECIAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGSGSEDLLNKHADFSKVFLAGDSAGANIAHHMTMRAAKEKPSPDLRDSGISGIILVHPYFWSKTPLDEKETTDKTLRSKIEAIWTMASPNSKEGSDDPWLNVVESETSDLSGLGCGRVLVLVAEKDALARQGWGYAAKLEKSGWKGEVELVESEGEEHVFHLTKPDCDKALQAMHKFAAFLKGHN
>Ibeam.0607s0010.1.v1.1
MLMGANTLTHVTSINPNNINIHGPVIDEVEGLIRVYKDGHVERPELIPCVGPSLALELGVDCSDVHIDKLTNVWARLYVPMVTKSLVSFSKFPLLVYFHGGGFCVGSASWSCYHEFLARLSASSRCLIMSVNYRLAPENPLSAAYEDGVNAIQWLKKTRNENVWASLCNFGRIFLAGDSAGGNIAHHVAAKLADAEDRIKPLKIEGTILIQPFFGGEARTESERRVGNNKKSSVLTLASSDAWWRLALPSGANREHPYCKPVKTVARTLVCVAEMDVLMDREMEMCDGNEKLIKRVVYKGVGHAFQILGKSQLAHTTTLEMLCHIDAFIHHYDPSLIS
>Ibeam.1086s0013.1.v1.1
MATISFSHNHHASRGGSNNHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVPPTLHPSAKVTAFDIKLSNDILTRVYIPLTSASPSVSTLPLVIYFHGGGFCVGSVAWSCYHDFLTNLAVKATCVVVSVNYRLAPEHRLPAAYDDGVNVVSWLVKQQISNNRGYNSNWVNKCNLSNVFLAGDSAGANIAYQVAVRITASGRYVNSLNLKGIILIHPFFGGESRTSSEILQQHHSKSTSALTLSASDTYWRLALPRGASRDHPWCNPFVNPENVLIREAKLPTTMVFVAEFDILKDRNLEMCRVMRSHVKRVECVVHGGVGHAFHVLDNSSVSSDRTHDMMCRLHNFINH
>Ibeam.1486s0006.1.v1.1
MDMESSIKKQVSLEVLPWLVVHSDGRLERLVGTEVCPPGLDQETHVLSKDIIIEPKTGLSARIYRPDTVRPGQKLPLVLYFHGGAFLISSAAFPFYHKSVNKLVAKANIIAVSVNYRLAPEHPLPTAYEDSWNAIQMIGSIKEPWINDYADFNRLFLIGDSAGANISHHLAFRDSAVKIKGVGMIHPYFWGTQPMGSEVNDEARKHMVDGWWEFVCPSEKGSDDPWINPFSDGSPELEELGCERVMITVAENDILRERGKMYYERLVKSKWKGKVEMMETKGKDHVFHIFEPDCHEAMEMLQNLALFINQA
>Ibeam.1550s0003.1.v1.1
MLRRITFSSSICLRHLSFRAFRQLPRSYLLSSPTTVGTSGRNPLRPSTLRCVSSHSSSEVAAEHPPFVRIYKNGRVERLSGTEIVPASLTPQNGVVSKDVVYLPEHNLSVRLFLSHKAADNNKLPLLIYIHGGAWIIQSPFSPIYHNFLSEVVKSANCLAMSIQYRRAPEHPIPAAYDDSWSAIQWILSHSVGSGGPEDWINKYADFDKVFLAGDSAGANISHHMAIKAGKEKLNPRIKGTAIVHPAFWGKDPVDEHDVQDREIRNEIARVWEKIASPNSVDGTDDPLFNVVGSGSDFSGMGCDKVLVAVAGKDVFVRQGLAYAKKLKKSGWEGEVEVIEDEDEDHCFHLLNPNSQNAPKFTKKFVEFITG
>Ibeam.1975s0007.1.v1.1
MDSDSEIAYDYSPRFRIYKNGRIQRLLNETFVPPSLNPENGVVSTDAVYSTEKNLSLRIYLPQNAVETDHHKKKRKLTLLVYFHGGGFIMESAFSPVYHTFLTSVVSASDCIAVSVNYRRAPEHPIPIAYEDSWDAIKWVFSHFAGSGPNDWLNENADYSMIFLAGDSAGANIAHHMVIRAGKEISGSGSGYGGLKISGLTLFHPFFLSNTPKEEHEVEGMRYFEGIWKIASPKSEKGVEDPWINVVGSDLSGLGCERVLVMVAGNDVLAKQGWRYAEELEKSGWEGKVEVTETKNEGHVFHLRKPLSDNSRLLLQRFVEFLN
>Ibeam.5413s0003.1.v1.1
MCVSLNISLSMDSEIAFDKFPYYRVYKSGRIERLHGETIVPPSLTPQNGVISKDTVYSSEKNLSLRIYLPEKVVETGKKLPVLVYFHGGGFIIETAFSPTYHTFLTSAVAAADCIAISVDYRRAPEFPIPIPYEDSWVSLKWVFSHISGSGPESWINKHADFSKVFLAGDSAGGNITHHLTIRAKREKLESVIFGIILIHPYFWGKTPIDELETRDETRRKMIEGNWGIASPNSKNGADDPLINVVGSESSDLSGLGCGRVLVMVAGDDNFVRQGIGYAEKLKKKSEWEGEVELMETENEGHVFHLRNPNTDNARKLVKNLAEFINK
>Ibeam.7917s0001.1.v1.1
MDSDSEIAYDYSPRFRIYKNGRIQRLLNETFVPPSLNPENGVVSTDAVYSTEKNLSLRIYLPQTDHHKKKRKLTLLVYFHGGGFIMESAFSPVYHTFLTSVVSASNCIAVSVNYRRAPEHPIPIAYEDSWDAIKWVFSHFAGSGPNDWLNENADYSMIFLAGDSAGANIAHHMVIRAGKEISGSGWGYGGLKISGLTLFHPFFLSNTPKEEHEVEGMRYFEGIWKIASPKSEKGVEDPWINVVGSDLSGLGCERVLVMVAGNDVLAKQGWRYAEELEKSGWEGKVEVTETKEEGHVFHLRKPQSDNYRLLLQRFVEFLN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University