Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Iberis amara
Species name
Bitter candytuft (Iberis amara) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Iberis_amara.CHS.fa
Download
>Ibeam.0009s0022.1.v1.1
MGSIDTTELSSEKKSNPGKATILALGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILKKYPELALEGQSTVKQRLDICNDAVTEMAVEASKACIKNWGGSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGALIIGSDPNLMSEKPLFELHTAIQNFLPGTEKTIDGRLTEQGINFTLSRELPQIIEDNVESFCEKLIGKAGLVDKDYNHMFWAVHPGGPAILNRIEKRLNLLPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESQKIKESENEWGLILAFGPGVTFEGIVARNLKTHVAL
>Ibeam.0449s0028.1.v1.1
MVMGASSLDEIRKAQRADGPATILAIGTANPSNHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENQNMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKILGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSLVEKPIFEMVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKEEKMRATRHVLSEYGNMSSACVLFILDEMRKKSLEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPI
>Ibeam.0485s0011.1.v1.1
MTSGRRVAHPGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDLSIRDKLQHLCKTTTVKTRYTVMTRETLQKYPELATEGSATIKQRLEISNEAVVQLAYEASLVCIKEWGRAVEDITHLIYVSSSEFRLPGGDLHLSAQLGLSNEVQRVLLYFLGCYGGVTGLRVAKDIAENNPGSRVLVTTSETMVLGFRPPSKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHYALQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEENVEEFCKKLVAKADTGSLELNDLFWAVHPGGPAILKGLETKLKLKAEKLESSRRALMDYGNVSSNTIFYIMEKVRDELEKKGEGGEEWGLGLAFGPGITFEGFLMRSLI
>Ibeam.3284s0006.1.v1.1
MSSWGMNGVKKQNSQVTTKRVANPGKATVLALGKAFPSQMVPQEKVVEGFLRDTKCEDAFIKEKLEHLCKTTTVKTRYTVLSREILEKYPELTTEGSPTLKQRLEIANEAVVEMAVEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDVYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPREYEAPFMELHYAVQQLLPGTQSVIDGRLSEEGINFKLGRDLPQKIEENIEEFCNKLMRKSGDEFMEFNDMFWAVHPGGPAILNRLETKLKLEKEKLESSRRALVDYGNVSSNTILYVMENVRDELKKKGDAAKEWGLGLAFGPGITFEGLLLRSLTSP
>Ibeam.5490s0002.1.v1.1
MVMGMTSSLDEIRKAQRADGPAGILAIGTANPSNHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVELKLGLKAEKMRATRHVLSEFGNMSSACVLFILDEMRRKSAEDGVATTGEGFEWGVLFGFGPGLTVETVVLHSVPV
MGSIDTTELSSEKKSNPGKATILALGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILKKYPELALEGQSTVKQRLDICNDAVTEMAVEASKACIKNWGGSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGALIIGSDPNLMSEKPLFELHTAIQNFLPGTEKTIDGRLTEQGINFTLSRELPQIIEDNVESFCEKLIGKAGLVDKDYNHMFWAVHPGGPAILNRIEKRLNLLPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESQKIKESENEWGLILAFGPGVTFEGIVARNLKTHVAL
>Ibeam.0449s0028.1.v1.1
MVMGASSLDEIRKAQRADGPATILAIGTANPSNHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENQNMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKILGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSLVEKPIFEMVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKEEKMRATRHVLSEYGNMSSACVLFILDEMRKKSLEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPI
>Ibeam.0485s0011.1.v1.1
MTSGRRVAHPGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDLSIRDKLQHLCKTTTVKTRYTVMTRETLQKYPELATEGSATIKQRLEISNEAVVQLAYEASLVCIKEWGRAVEDITHLIYVSSSEFRLPGGDLHLSAQLGLSNEVQRVLLYFLGCYGGVTGLRVAKDIAENNPGSRVLVTTSETMVLGFRPPSKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHYALQQFLPGTQGVIDGRLSEEGISFKLGRDLPQKIEENVEEFCKKLVAKADTGSLELNDLFWAVHPGGPAILKGLETKLKLKAEKLESSRRALMDYGNVSSNTIFYIMEKVRDELEKKGEGGEEWGLGLAFGPGITFEGFLMRSLI
>Ibeam.3284s0006.1.v1.1
MSSWGMNGVKKQNSQVTTKRVANPGKATVLALGKAFPSQMVPQEKVVEGFLRDTKCEDAFIKEKLEHLCKTTTVKTRYTVLSREILEKYPELTTEGSPTLKQRLEIANEAVVEMAVEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDVYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPREYEAPFMELHYAVQQLLPGTQSVIDGRLSEEGINFKLGRDLPQKIEENIEEFCNKLMRKSGDEFMEFNDMFWAVHPGGPAILNRLETKLKLEKEKLESSRRALVDYGNVSSNTILYVMENVRDELKKKGDAAKEWGLGLAFGPGITFEGLLLRSLTSP
>Ibeam.5490s0002.1.v1.1
MVMGMTSSLDEIRKAQRADGPAGILAIGTANPSNHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVELKLGLKAEKMRATRHVLSEFGNMSSACVLFILDEMRRKSAEDGVATTGEGFEWGVLFGFGPGLTVETVVLHSVPV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University