Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in flavonoid biosynthesis.
C4H
Enzyme
Cinnamate 4-hydroxylase
Enzyme name
EC:1.14.14.91
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Sysname
trans-cinnamate + [reduced NADPH---hemoprotein reductase] + O2 = 4-hydroxycinnamate + [oxidized NADPH---hemoprotein reductase] + H2O[RN:R02253]
Reaction
4-hydroxycinnamate [CPD:C00811];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Iberis amara
Species name
Bitter candytuft (Iberis amara) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Iberis_amara.C4H.fa
Download
>Ibeam.0453s0007.1.v1.1
MDLLFLEKSLIVVFVAVVLATVISKLRGKKLKLPPGRTPIPIFGNGLQVRDELNHRNLVDYAKKFGDLLLLRMGQRNLVVISSPDLTKEVIHTHGVKFGSRTTNVVFDIFKGKGQDMVFTVYGEHWRKIVVKDVKKNPDSITKGIVLRKCLQLMMYNNMFRIIFDRSFEYKYGDFIPILRPFLRGYLKICQEVKDQRLEFFKKYFVDGRKRGEINEDNVLYIVENINVAAIETTLRSIEWGIAELVNHPEIHSKLRNEIDTVLGPGVQVTEPELHKLPYLQVVIKETLRLRIAISLLVPHMNLNDAKLAGYDIPAESKILSMLEFRPERFFEEEAHMEANGNDFRYVPFGVGRRSCPRIILALPILGITIGRMV
>Ibeam.1970s0006.1.v1.1
MDLLLLEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQSKLRNEIDTVLGPGVQVTEPELHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKILVNAWWLANNPSSWKKPEEFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTSEKGGQFSLHILNHSTIVLKPRTF
>Ibeam.1970s0008.1.v1.1
MDLLLVEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQSKLRNEIDTILGPGVQVTEPELHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKILVNAWWLANNPSSWKKPEEFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTSEKGGQFSLHILNHSTIVLKPRTF
>Ibeam.2613s0003.1.v1.1
MDLLLLEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQNKLRNEIDTXD
>Ibeam.2613s0005.1.v1.1
MDLLLVEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQNKLRNEIDTVLGPGVQVTEPELHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKILVNAWWLANNPSSWKKPEEFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTSEKGGQFSLHILNHSTIVLKPRTF
>Ibeam.6874s0005.1.v1.1
MDLLFLEKSLIAVFIAVVLATVISKLHGKKLKLPPGPTPIPIFGNWLQVRDELNHRNLVDYAKKFGDLLLLRMGQRNLVVISSPDLTKEVIHTQGVEFGSRTRNVVFDIFTGKGQDMVFTIYGEHWRKMRQIMTVPFFTNKVDVKKNPYSVTKGIILRKRLQLMMYNNMFRIIFDRRFDSEDDPLFLQLKALNGEISRLAQSFEYNYGDFIPILRPFLRGYLKICQEGEINEDNILYIVENINVAAIETTLRSIEWGITELVNRPEIKSKLRNEIDTVLGPGVQVTEPELHKLLYLQAVIKETLRLRMTIPLLVPHMNLNDAKLAGYDIPAERKILFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPRIIVALPILGITIGRMVQNFELLLPPEQSKVDTSEKDGQFSLHILKHSTIFMKPREA
MDLLFLEKSLIVVFVAVVLATVISKLRGKKLKLPPGRTPIPIFGNGLQVRDELNHRNLVDYAKKFGDLLLLRMGQRNLVVISSPDLTKEVIHTHGVKFGSRTTNVVFDIFKGKGQDMVFTVYGEHWRKIVVKDVKKNPDSITKGIVLRKCLQLMMYNNMFRIIFDRSFEYKYGDFIPILRPFLRGYLKICQEVKDQRLEFFKKYFVDGRKRGEINEDNVLYIVENINVAAIETTLRSIEWGIAELVNHPEIHSKLRNEIDTVLGPGVQVTEPELHKLPYLQVVIKETLRLRIAISLLVPHMNLNDAKLAGYDIPAESKILSMLEFRPERFFEEEAHMEANGNDFRYVPFGVGRRSCPRIILALPILGITIGRMV
>Ibeam.1970s0006.1.v1.1
MDLLLLEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQSKLRNEIDTVLGPGVQVTEPELHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKILVNAWWLANNPSSWKKPEEFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTSEKGGQFSLHILNHSTIVLKPRTF
>Ibeam.1970s0008.1.v1.1
MDLLLVEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQSKLRNEIDTILGPGVQVTEPELHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKILVNAWWLANNPSSWKKPEEFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTSEKGGQFSLHILNHSTIVLKPRTF
>Ibeam.2613s0003.1.v1.1
MDLLLLEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQNKLRNEIDTXD
>Ibeam.2613s0005.1.v1.1
MDLLLVEKSLIAVFVAVVLATVISKLRGKKLKLPPGPIPIPVFGNWLQVGDDLNHRNLVDYAKKFGDLFLLRMGQRNLVVVSSPNLTKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNREGWEFEAASVVEDVKKNPDSATKGIVLRKRLQLMMYNNMFRIMFDRRFESEDDPLFLRLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKDVKDRRLALFKKYFVDERKQIASAKPTGNEGLKCAIDHILEAQEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQNKLRNEIDTVLGPGVQVTEPELHKLPYLQAVIKETLRLRMAIPLLVPHMNLNDAKLAGYDIPAESKILVNAWWLANNPSSWKKPEEFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKLDTSEKGGQFSLHILNHSTIVLKPRTF
>Ibeam.6874s0005.1.v1.1
MDLLFLEKSLIAVFIAVVLATVISKLHGKKLKLPPGPTPIPIFGNWLQVRDELNHRNLVDYAKKFGDLLLLRMGQRNLVVISSPDLTKEVIHTQGVEFGSRTRNVVFDIFTGKGQDMVFTIYGEHWRKMRQIMTVPFFTNKVDVKKNPYSVTKGIILRKRLQLMMYNNMFRIIFDRRFDSEDDPLFLQLKALNGEISRLAQSFEYNYGDFIPILRPFLRGYLKICQEGEINEDNILYIVENINVAAIETTLRSIEWGITELVNRPEIKSKLRNEIDTVLGPGVQVTEPELHKLLYLQAVIKETLRLRMTIPLLVPHMNLNDAKLAGYDIPAERKILFRPERFFEEEAHVEANGNDFRYVPFGVGRRSCPRIIVALPILGITIGRMVQNFELLLPPEQSKVDTSEKDGQFSLHILKHSTIFMKPREA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University