Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Hydrangea quercifolia
Species name
Hydrangea quercifolia is a species of eudicot in the family Hydrangeaceae (hydrangea family).
Species info
Gene sequence info
Hydrangea_quercifolia.COMT.fa
Download
>Hyque.07G164400.1.v1.1
MGSTSDNQTVNPPDVEEEACLFAMQLASASVLPMVLKSAIELDLLETMAKAGPRAYVSPSELAAQLPTQNKDAPVMLDRILRLLASYSVLDCTVKNLPNGGVERLYSLAPVCKYLTRNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTITMKKILETYKGFEGLTSVVDVGGGTGATLNMIISKYPSIKGFNFDLPHVIEDAPSYTGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYEALPNNGKVIVAECILPVAPDTRLATRNVIHIDVIMLAHNPGGKERTEKEFEALAKGAGFQGFRVMCSAFNTWVMEFLKSQVNELHIYQIHFIDFAQYAEEEACLFAMQLASASVLPLVLRSAIELDLLETMAKAGPGAYVSPSELAAQLPTQNKDASVMLDRILRLLASYSVLDCTVKNLPNGGVERLYSLAPVYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTVTMKKILETYKGFEGLTSVVDVGGGTGATLNMIISKYPSIKGFNFDLPHVISKRTFETIMQFLKLFRQYYLHFGPRNNVGLRSVEHVGGDMFVSVPNGDAIFMKWICHDWSDEHCLKFLKNCYEALPNNGKVIVVECILLVAPDTRLATRHVIHMDVILLAHNPGGKGRTEKEFEALAKGAGFQGFRVMCCAFNTWVIEFLKNCY
>Hyque.16G078000.1.v1.1
MIKPNEEFQLFLKALQFGGTSILQGVFRAALELGLFEIMAKAGSGAHLSSSEIASQLPTKNPDAPDLLDRMLRLLASYSVLTCQLVTNKNGDAIRLYGLAPICKYFVRNQDGVSIVPPILFLIDKVIANSWYHLKDAVLEGGIPFNKAYGMHIFEYTGIDSRFSEVFNEAMNSSSGDNMAIILGAYKGFEDLNEIVDVGGGCGVTLDSIITMYPNIKGINFDLPHVIKDAPTWPGVEHVGGDMFEDVPNGKVILLKRVLHDWSDDQCLKLLKNCYKALPEFGKVIVIDMILPEYPETDLISNNIFSFDVSMLTITPGGRERTEKELEALAKGAGFAASKLVCHAGLYGVIEFYKKMAIDTQN
>Hyque.17G001900.1.v1.1
MGGGQPTNQKEKKKKKMEWCGKDEPKIGNSEEDEQLSYALQLSNMSVMPMVLKAAIDLELLEIIAKAGPGAQLSPTEIVGQMPTRNPDAPSMVDRILRLLASYSVLSCSLHNDGHRLYGLAPVAKYYVRNNELDGASFGPLMALIHDKVFMDTWYALKDAVLEGGVPFDKVHGMQAFDYPGNDPRFNEAFNKAMTNHTTIVIKKILECYKGFDHLKQLVDVGGGLGVNLNMIVSKYPNIKGINFDLPHVIQHAPSYPGVEHIGGDMFVDVPKADAIFMKWILHDWSDDHCLKLLRNCYKALPEDGKVIVVEAILPVIPNNSVSVKTICQVDLVMMTQNPGGKERTQQEFLDLAIGAGFSGITLECFASNIWVIEFYKYLAI
MGSTSDNQTVNPPDVEEEACLFAMQLASASVLPMVLKSAIELDLLETMAKAGPRAYVSPSELAAQLPTQNKDAPVMLDRILRLLASYSVLDCTVKNLPNGGVERLYSLAPVCKYLTRNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTITMKKILETYKGFEGLTSVVDVGGGTGATLNMIISKYPSIKGFNFDLPHVIEDAPSYTGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYEALPNNGKVIVAECILPVAPDTRLATRNVIHIDVIMLAHNPGGKERTEKEFEALAKGAGFQGFRVMCSAFNTWVMEFLKSQVNELHIYQIHFIDFAQYAEEEACLFAMQLASASVLPLVLRSAIELDLLETMAKAGPGAYVSPSELAAQLPTQNKDASVMLDRILRLLASYSVLDCTVKNLPNGGVERLYSLAPVYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTVTMKKILETYKGFEGLTSVVDVGGGTGATLNMIISKYPSIKGFNFDLPHVISKRTFETIMQFLKLFRQYYLHFGPRNNVGLRSVEHVGGDMFVSVPNGDAIFMKWICHDWSDEHCLKFLKNCYEALPNNGKVIVVECILLVAPDTRLATRHVIHMDVILLAHNPGGKGRTEKEFEALAKGAGFQGFRVMCCAFNTWVIEFLKNCY
>Hyque.16G078000.1.v1.1
MIKPNEEFQLFLKALQFGGTSILQGVFRAALELGLFEIMAKAGSGAHLSSSEIASQLPTKNPDAPDLLDRMLRLLASYSVLTCQLVTNKNGDAIRLYGLAPICKYFVRNQDGVSIVPPILFLIDKVIANSWYHLKDAVLEGGIPFNKAYGMHIFEYTGIDSRFSEVFNEAMNSSSGDNMAIILGAYKGFEDLNEIVDVGGGCGVTLDSIITMYPNIKGINFDLPHVIKDAPTWPGVEHVGGDMFEDVPNGKVILLKRVLHDWSDDQCLKLLKNCYKALPEFGKVIVIDMILPEYPETDLISNNIFSFDVSMLTITPGGRERTEKELEALAKGAGFAASKLVCHAGLYGVIEFYKKMAIDTQN
>Hyque.17G001900.1.v1.1
MGGGQPTNQKEKKKKKMEWCGKDEPKIGNSEEDEQLSYALQLSNMSVMPMVLKAAIDLELLEIIAKAGPGAQLSPTEIVGQMPTRNPDAPSMVDRILRLLASYSVLSCSLHNDGHRLYGLAPVAKYYVRNNELDGASFGPLMALIHDKVFMDTWYALKDAVLEGGVPFDKVHGMQAFDYPGNDPRFNEAFNKAMTNHTTIVIKKILECYKGFDHLKQLVDVGGGLGVNLNMIVSKYPNIKGINFDLPHVIQHAPSYPGVEHIGGDMFVDVPKADAIFMKWILHDWSDDHCLKLLRNCYKALPEDGKVIVVEAILPVIPNNSVSVKTICQVDLVMMTQNPGGKERTQQEFLDLAIGAGFSGITLECFASNIWVIEFYKYLAI
Sheng jun & Dong yang Teams, Yunnan agriculture University