Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Hydrangea quercifolia
Species name
Hydrangea quercifolia is a species of eudicot in the family Hydrangeaceae (hydrangea family).
Species info
Gene sequence info
Hydrangea_quercifolia.OMT.fa
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>Hyque.03G202500.1.v1.1
MEGEATSNYKEKEEEAQAKVDIWKYVFGFVDMAVVKCAIELGIADVLEAHDGPMTLSDLSTTLRCSPAALHRIMRFLVHRKIFKEDFTKCQAGGGPNINISYVQTPLSRLLMKNGENNMASFVLLESSPVMLAPWHALSSRVLANGNISAFEAAHGDDIWRYAAENPGHSKLIDDAMACDARVAVPAIIDGCPEVFDGLSSLVDVGGGNGTALQMIVKACPWIHGINFDLPHVVSVAPNYDGVEHVGGDMFDSIPKADAAFFMWVLHDWADDECIKILKKCREAIPKDKGKVIIVEGVIEEDEGDKLKYVRLMLDMVMMAHTNRGKERTLKEWAYVLGEAGFSRHTVNRIQAVQSIIEAYP
>Hyque.06G177400.1.v1.1
MEGENHIDAEAMLRGQAEIWQFMFNFADSMALKCAVELRIADIIHSHGCPITLSQIISNINKSHSPDITCLARIMRLLVRKKIFTVDHQSDGGTQDTLLYGLTHSSKWLLHDSELSLAPMLLMENHPLLLAPWHHLSGCVREGGIAFKKAHGHEIWDFASVNHGFNQLFNDGMECTAKITTKAIITGYRDGFGRIGSVVDVGGGTGAAMAEIVKAHPHIKGLNFDLPHVVATAPVYQGVCHVGGDMFAAIPNADAVFMKWIMHDWNDEDCVKILKNCRKAIPKKTGKVIIVDVVLEPEGDGLFDNTGLAFDLLMIAHSSGGKERTEVEWKKLLEEGGFPRYNIIKIPALQSIIEAYPE
>Hyque.06G174800.1.v1.1
MEKQLDREALHDTILQGQVDIWRYLYNFVESMALKCAVELQIPDIIHSHGSPITLSQIANGIASPTIDKTCLVRIMKFLVHMKIFDEYSPPFNGEEVLYHLTPSSKWLLHDSELNLVPLVKMRNHPYILQPFHFLSRCVKEGGTAFHKAHGCEMWDFASVNLEFNKIFNDGMECTTKITTRAMISAYKDGFGSIGSMVDVGGGTGMAVAEIVKAYPHIKGINFGLPHVVATAPMHQCTMV
>Hyque.12G097700.1.v1.1
MGNEDESYIEQHKAQAHIWGQTLNFINSASLKCAVQLGIPDVIHNHGKPMTLSELVVALPLNPSKSHCIYRLMRVLIHSRFFALQKLGEDEQEEGYCLTPASRLLLKDEPMNARAFLLVGLDPILTKPWHFLSDWFQNNDVTAFETAHARTFWDYNAYEQRLGSLFNEAMAGDSRLITNVLIHNCKQVFEGLTTLVDVGGGTGTVARAIAKTFPDLKCTVFDLPNVVADLQGSKNLDFVGGDMFETIPNANAILLKSILHNWSDDECVKILKKCKEVIPSKEDGGKVIIIDMNMENDESVEAQLFFDMLMMVVFTGKERKEKEWAKLFSAAGYSNYKITPTLGLRSLIEVYP
>Hyque.12G097500.1.v1.1
MANDDESHIELLKAQAHIWDQTFNFINSASLKCAVQLGIPDVIHNHGKPMTLSELVAALPINPSKYRCIYRLMRVLVHSRFFVLQKLGEDEQEEGYCLTPASRLLLKDEPLNARAFLLVELDPILTKPWHFLTDWFQNNDVTAFETAHGKTFWDYNAYEPRLGNFFNEAMAGDSRLITNVLIHDCKQVFEGLTTLVDVGGGTGTVARAISKTFPDLKCTVLDLPSVVADLQGSKNLDFVGGDMFETIPNANAILLKWILHDWSDDECVKILKKCKEAIPSKEEGGKVIIIDMNMENQKEDDESVEAQLFFDMLMMVVLTGKERNEKEWAKLFSAAGYSNYKITPMLGLRSLIEVYP
>Hyque.12G097600.1.v1.1
MSLKCAIQLNIPDIIHKHGQPMTLSELVSALPINRAKAQCVYRLMSILVQANFFIKQKLPQEDKEEEEKEGYSLTPASRLLLKEEPLGVTPFLLAMLDPILVTPWHHLSQWFENGDRTPFHTAHGRALWDYAGHEPRLNHFFNEAMASDARLVMSVVVKECRGVFEGLKSLVDVGGGIGTVAKVVVDAFPELECTVFDLPHVVADLEGSRNLKFVGGDMFESVPRADAILLKWILHDWNDEESVQILKKCKEAINPSKVHENGGGKVIIIDMITEENDQKEDNNNESMETQLFFDMLMMVLVGGRERKEREWAKLFFDAGFSDYKIIPILGLRSLIEVYP
>Hyque.18G025600.1.v1.1
MDFNHGQESSELFQAQAHIYKHIFNFAHSMCLGCAIKLGIPDIIHNHNQPMTLHELVSQLQIPPNKTQSVHRLMRLLVHSGFFATTKFISNDQEEKQGYVLTLSSKLLIKSQPTSLSPFVEANVNPIMVTPWQFLGDWLKGNELTVFETAHGFGLWDCGDQNPQFANIFNEAMASDSQMMCLAVKECEEIFGGLGSLVDVGGGTGVIAQIILGAFPHIKCTVFDLPHVVDNLMESKNLSYVGGDMFQSIPSADAILFKCVLHNWSDEDCVKILKRCREAITSTDKGGKVIIIDMVVNDEKDKHDITETKLLFDLLMMVLTTGRERNEREWEKLFLEAGFSHYKITPIMGLRSLIEVYP
MEGEATSNYKEKEEEAQAKVDIWKYVFGFVDMAVVKCAIELGIADVLEAHDGPMTLSDLSTTLRCSPAALHRIMRFLVHRKIFKEDFTKCQAGGGPNINISYVQTPLSRLLMKNGENNMASFVLLESSPVMLAPWHALSSRVLANGNISAFEAAHGDDIWRYAAENPGHSKLIDDAMACDARVAVPAIIDGCPEVFDGLSSLVDVGGGNGTALQMIVKACPWIHGINFDLPHVVSVAPNYDGVEHVGGDMFDSIPKADAAFFMWVLHDWADDECIKILKKCREAIPKDKGKVIIVEGVIEEDEGDKLKYVRLMLDMVMMAHTNRGKERTLKEWAYVLGEAGFSRHTVNRIQAVQSIIEAYP
>Hyque.06G177400.1.v1.1
MEGENHIDAEAMLRGQAEIWQFMFNFADSMALKCAVELRIADIIHSHGCPITLSQIISNINKSHSPDITCLARIMRLLVRKKIFTVDHQSDGGTQDTLLYGLTHSSKWLLHDSELSLAPMLLMENHPLLLAPWHHLSGCVREGGIAFKKAHGHEIWDFASVNHGFNQLFNDGMECTAKITTKAIITGYRDGFGRIGSVVDVGGGTGAAMAEIVKAHPHIKGLNFDLPHVVATAPVYQGVCHVGGDMFAAIPNADAVFMKWIMHDWNDEDCVKILKNCRKAIPKKTGKVIIVDVVLEPEGDGLFDNTGLAFDLLMIAHSSGGKERTEVEWKKLLEEGGFPRYNIIKIPALQSIIEAYPE
>Hyque.06G174800.1.v1.1
MEKQLDREALHDTILQGQVDIWRYLYNFVESMALKCAVELQIPDIIHSHGSPITLSQIANGIASPTIDKTCLVRIMKFLVHMKIFDEYSPPFNGEEVLYHLTPSSKWLLHDSELNLVPLVKMRNHPYILQPFHFLSRCVKEGGTAFHKAHGCEMWDFASVNLEFNKIFNDGMECTTKITTRAMISAYKDGFGSIGSMVDVGGGTGMAVAEIVKAYPHIKGINFGLPHVVATAPMHQCTMV
>Hyque.12G097700.1.v1.1
MGNEDESYIEQHKAQAHIWGQTLNFINSASLKCAVQLGIPDVIHNHGKPMTLSELVVALPLNPSKSHCIYRLMRVLIHSRFFALQKLGEDEQEEGYCLTPASRLLLKDEPMNARAFLLVGLDPILTKPWHFLSDWFQNNDVTAFETAHARTFWDYNAYEQRLGSLFNEAMAGDSRLITNVLIHNCKQVFEGLTTLVDVGGGTGTVARAIAKTFPDLKCTVFDLPNVVADLQGSKNLDFVGGDMFETIPNANAILLKSILHNWSDDECVKILKKCKEVIPSKEDGGKVIIIDMNMENDESVEAQLFFDMLMMVVFTGKERKEKEWAKLFSAAGYSNYKITPTLGLRSLIEVYP
>Hyque.12G097500.1.v1.1
MANDDESHIELLKAQAHIWDQTFNFINSASLKCAVQLGIPDVIHNHGKPMTLSELVAALPINPSKYRCIYRLMRVLVHSRFFVLQKLGEDEQEEGYCLTPASRLLLKDEPLNARAFLLVELDPILTKPWHFLTDWFQNNDVTAFETAHGKTFWDYNAYEPRLGNFFNEAMAGDSRLITNVLIHDCKQVFEGLTTLVDVGGGTGTVARAISKTFPDLKCTVLDLPSVVADLQGSKNLDFVGGDMFETIPNANAILLKWILHDWSDDECVKILKKCKEAIPSKEEGGKVIIIDMNMENQKEDDESVEAQLFFDMLMMVVLTGKERNEKEWAKLFSAAGYSNYKITPMLGLRSLIEVYP
>Hyque.12G097600.1.v1.1
MSLKCAIQLNIPDIIHKHGQPMTLSELVSALPINRAKAQCVYRLMSILVQANFFIKQKLPQEDKEEEEKEGYSLTPASRLLLKEEPLGVTPFLLAMLDPILVTPWHHLSQWFENGDRTPFHTAHGRALWDYAGHEPRLNHFFNEAMASDARLVMSVVVKECRGVFEGLKSLVDVGGGIGTVAKVVVDAFPELECTVFDLPHVVADLEGSRNLKFVGGDMFESVPRADAILLKWILHDWNDEESVQILKKCKEAINPSKVHENGGGKVIIIDMITEENDQKEDNNNESMETQLFFDMLMMVLVGGRERKEREWAKLFFDAGFSDYKIIPILGLRSLIEVYP
>Hyque.18G025600.1.v1.1
MDFNHGQESSELFQAQAHIYKHIFNFAHSMCLGCAIKLGIPDIIHNHNQPMTLHELVSQLQIPPNKTQSVHRLMRLLVHSGFFATTKFISNDQEEKQGYVLTLSSKLLIKSQPTSLSPFVEANVNPIMVTPWQFLGDWLKGNELTVFETAHGFGLWDCGDQNPQFANIFNEAMASDSQMMCLAVKECEEIFGGLGSLVDVGGGTGVIAQIILGAFPHIKCTVFDLPHVVDNLMESKNLSYVGGDMFQSIPSADAILFKCVLHNWSDEDCVKILKRCREAITSTDKGGKVIIIDMVVNDEKDKHDITETKLLFDLLMMVLTTGRERNEREWEKLFLEAGFSHYKITPIMGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University