Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Hydrangea quercifolia
Species name
Hydrangea quercifolia is a species of eudicot in the family Hydrangeaceae (hydrangea family).
Species info
Gene sequence info
Hydrangea_quercifolia.CHS.fa
Download
>Hyque.02G074900.1.v1.1
MFTVDEVRRAQRAQGPATIMAIGTANPPNCVDQNTYPDYYFRITNSEHKKELKEKFKRICDKSQIKKRYMYLTEEILKKNPNICAYMAHSLDTRQDMMVVEVPKLGKEAATKAIKEWGQPKSMITHLVFCSTGGVDLPGADYQLIKLLGLQPSVKRLMLYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITVVTFRGPSDHPHLDNLVGQALFGDGAAAMIIGSDPVPIVEKPLFELVSAAQTILPDSDSAIEGHLREVGLTFHLLEDVPRLISKNIEKSLVEVFQPLGISNWNSIFWIAHPGGPAILDQVEKKLGLEPEKLRATRHVLSEYGNMSSACVLFILDEMRKNSVEDGLKTTGEGLEWGVLFGFGPGLTIETVVLHGVAI
>Hyque.02G075000.1.v1.1
MVTVEEVRKAQRAHGPATIMAIGTATPSNCVDQSTYPDYYFRITNSEHKKELKEKFKRMCDNSQIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPITEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLVEAFQPLGISDWNSIFWIAHPGGPAILDQVEKKLGLAPEKLRATRHVLSEYGNMSSACVLFILDEMRKNSAENGLKTTGEGLEWGVLFGFGPGLTVETIVLHGVST
>Hyque.02G074800.1.v1.1
MFTVDEVRRAQRAQGPATIMAIGTATPTNCVDQSTYPDYYFRITNSEHKKELKEKFKRICDKSQIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVVCTTSGVDMPGADYQLTKLLGLQPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPIPDVENPLFELVSAAQTILPDSDGAIEGHLREVGLTFHLLEDIPWLISKNIEKSLVEVFQPLGISDWNSIFWIAHPGGPAILDQVEKKLGLEPEKLRATRHVLSEYGNMSSACVLFILDEMRKNSVEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHGVSI
>Hyque.03G193900.1.v1.1
MGSEEIVQACSSRKANPGTATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPDLKERLTRLCRTTTVKTRYVVMSEEILKKYPELAIEGLPTVTQRLEICNKAVTRMAIEASQSCIKNWGRPISDITHLVYVSSSEARLPGGDLYLASGLGLNPETNRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPNVDRPYDLVGVALFGDGAGAMIIGSDPVLGIERPLFELHTAIQSFLPNTEKIIDGRLTEEGISFKLSRDLPQIIEDHIEGFCDNLMKIVGNCDKDYNKMFWAVHPGGPAILNRLEKKLDLLPDKLSASRRALADYGNASSNTIVYVLEYMIAENLKMKNENHGENEWGLILAFGPGVTFEGILARNLTV
>Hyque.05G053800.1.v1.1
MAAISSSVVIEIEDMCKAQKAVGPATILAIGTATPSNCVYQSEYPDFYFRITNSDHLTHLKRKFKRMCERSMIKKRYMHLTEEILKENPNICAYMAPSIDTRQDIVVVEIPKLAKEAASKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLCPSVKRLMMYQQGCYAGGTGLRLAKDLAENNKGARVLVVCSEMTVINFRGPSEAHLDSLVGQSLFGDGASAVIVGADPDRSLEHPLFQIVSAAQTIVPNSDGAVEGHLRDVGLTFHLLKDVPSLISDNIEKSLVNAFTPLMGHNNDVGKSTIIDWNSIFWITHPGGPAILDQVEAKLDLHEEKLRVSRHVLSEYGNMSSACVLFIMDEMRKRSVEEGKGTTGEGLEWGVLFGFGPGLTIETVVLHSVPI
>Hyque.10G121900.1.v1.1
MVTVEEVRKAQRAQGPATVLAIGTATPPNCVDQSTYPDYYFRVTNSEHKKELKEKFQRMCDNSQIKKRYMYLTEEILKENPNICAYMAPSLDARQDMVVVEIPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGSDPVPEVEKPLFEIVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFRPLDISDWNSLFWIAHPGGPAILDQVEKKLALKPEKLRATRNVLSDYGNMSSACVLFIMDEMRKKSAEEGLMTTGEGLEWGVLFGFGPGLTVETVVLHGVST
>Hyque.10G055800.1.v1.1
MSTMKNGNSKCYGSPSMRVPTLGKATILAMGKAFPSQLVPQDCLVEGYCRDTKCDDLAIKEKLERLCKTTTVKTRYTVMSREILDKYPELTTEGSPTIQQRLEIANPAVLEMAKKASLNCIQEWGRPAGDITHIVYVSSSEIRLPGGDLYLASQLGLRNDIRRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTSPFLEQECPFLELNYAVQKFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEDNIEEFCKKLMEKSCLDDFNDLFWAVHPGGPAILNRLETKLCLKTDKLDCSRRALMDFGNVSSNTIFYVIEYMREKLKKEKGEEWGLALAFGPGITFEGILMRSL
>Hyque.10G122000.1.v1.1
MVLRLAKDLAENNEGARVLVVCSEITAAIFRGPSEAQIDSLIGQALFGDGASAVIVGSEPVPSIENPLFELVSTAQTILPDSDGALELHVREAGLTFHLRWDVPNIISNNIEQSLVEAFQPWGISDWNSIFWIVHPGGPAILDKVEAKLGLKPEKLRATRHVLSEYGNLTSGCVLFILDEIRKKSAKEGLQTTGEGLEWGVLFGFGPGLTMETLVLRSVFII
>Hyque.S015000.1.v1.1
MSREILDKYPELTTEGSPTIQQRLEIANPAVLEMAKKASLNCIQEWGRPAGDITHIVYVSSSEIRLPGGDLYLASQLGLRNDIRRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTSPFLEQECPFLELNYAVQKFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEDNIEEFCKKLMEKSCLDDFNDLFWAVHPGGPAILNRLETKLCLKTDKLDCSRRALMDFGNVSSNTIFYVIEYMREKLKKEKGEEWGLALAFGPGITFEGILMRSL
MFTVDEVRRAQRAQGPATIMAIGTANPPNCVDQNTYPDYYFRITNSEHKKELKEKFKRICDKSQIKKRYMYLTEEILKKNPNICAYMAHSLDTRQDMMVVEVPKLGKEAATKAIKEWGQPKSMITHLVFCSTGGVDLPGADYQLIKLLGLQPSVKRLMLYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITVVTFRGPSDHPHLDNLVGQALFGDGAAAMIIGSDPVPIVEKPLFELVSAAQTILPDSDSAIEGHLREVGLTFHLLEDVPRLISKNIEKSLVEVFQPLGISNWNSIFWIAHPGGPAILDQVEKKLGLEPEKLRATRHVLSEYGNMSSACVLFILDEMRKNSVEDGLKTTGEGLEWGVLFGFGPGLTIETVVLHGVAI
>Hyque.02G075000.1.v1.1
MVTVEEVRKAQRAHGPATIMAIGTATPSNCVDQSTYPDYYFRITNSEHKKELKEKFKRMCDNSQIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPITEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLVEAFQPLGISDWNSIFWIAHPGGPAILDQVEKKLGLAPEKLRATRHVLSEYGNMSSACVLFILDEMRKNSAENGLKTTGEGLEWGVLFGFGPGLTVETIVLHGVST
>Hyque.02G074800.1.v1.1
MFTVDEVRRAQRAQGPATIMAIGTATPTNCVDQSTYPDYYFRITNSEHKKELKEKFKRICDKSQIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVVCTTSGVDMPGADYQLTKLLGLQPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPIPDVENPLFELVSAAQTILPDSDGAIEGHLREVGLTFHLLEDIPWLISKNIEKSLVEVFQPLGISDWNSIFWIAHPGGPAILDQVEKKLGLEPEKLRATRHVLSEYGNMSSACVLFILDEMRKNSVEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHGVSI
>Hyque.03G193900.1.v1.1
MGSEEIVQACSSRKANPGTATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPDLKERLTRLCRTTTVKTRYVVMSEEILKKYPELAIEGLPTVTQRLEICNKAVTRMAIEASQSCIKNWGRPISDITHLVYVSSSEARLPGGDLYLASGLGLNPETNRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPNVDRPYDLVGVALFGDGAGAMIIGSDPVLGIERPLFELHTAIQSFLPNTEKIIDGRLTEEGISFKLSRDLPQIIEDHIEGFCDNLMKIVGNCDKDYNKMFWAVHPGGPAILNRLEKKLDLLPDKLSASRRALADYGNASSNTIVYVLEYMIAENLKMKNENHGENEWGLILAFGPGVTFEGILARNLTV
>Hyque.05G053800.1.v1.1
MAAISSSVVIEIEDMCKAQKAVGPATILAIGTATPSNCVYQSEYPDFYFRITNSDHLTHLKRKFKRMCERSMIKKRYMHLTEEILKENPNICAYMAPSIDTRQDIVVVEIPKLAKEAASKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLCPSVKRLMMYQQGCYAGGTGLRLAKDLAENNKGARVLVVCSEMTVINFRGPSEAHLDSLVGQSLFGDGASAVIVGADPDRSLEHPLFQIVSAAQTIVPNSDGAVEGHLRDVGLTFHLLKDVPSLISDNIEKSLVNAFTPLMGHNNDVGKSTIIDWNSIFWITHPGGPAILDQVEAKLDLHEEKLRVSRHVLSEYGNMSSACVLFIMDEMRKRSVEEGKGTTGEGLEWGVLFGFGPGLTIETVVLHSVPI
>Hyque.10G121900.1.v1.1
MVTVEEVRKAQRAQGPATVLAIGTATPPNCVDQSTYPDYYFRVTNSEHKKELKEKFQRMCDNSQIKKRYMYLTEEILKENPNICAYMAPSLDARQDMVVVEIPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGSDPVPEVEKPLFEIVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFRPLDISDWNSLFWIAHPGGPAILDQVEKKLALKPEKLRATRNVLSDYGNMSSACVLFIMDEMRKKSAEEGLMTTGEGLEWGVLFGFGPGLTVETVVLHGVST
>Hyque.10G055800.1.v1.1
MSTMKNGNSKCYGSPSMRVPTLGKATILAMGKAFPSQLVPQDCLVEGYCRDTKCDDLAIKEKLERLCKTTTVKTRYTVMSREILDKYPELTTEGSPTIQQRLEIANPAVLEMAKKASLNCIQEWGRPAGDITHIVYVSSSEIRLPGGDLYLASQLGLRNDIRRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTSPFLEQECPFLELNYAVQKFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEDNIEEFCKKLMEKSCLDDFNDLFWAVHPGGPAILNRLETKLCLKTDKLDCSRRALMDFGNVSSNTIFYVIEYMREKLKKEKGEEWGLALAFGPGITFEGILMRSL
>Hyque.10G122000.1.v1.1
MVLRLAKDLAENNEGARVLVVCSEITAAIFRGPSEAQIDSLIGQALFGDGASAVIVGSEPVPSIENPLFELVSTAQTILPDSDGALELHVREAGLTFHLRWDVPNIISNNIEQSLVEAFQPWGISDWNSIFWIVHPGGPAILDKVEAKLGLKPEKLRATRHVLSEYGNLTSGCVLFILDEIRKKSAKEGLQTTGEGLEWGVLFGFGPGLTMETLVLRSVFII
>Hyque.S015000.1.v1.1
MSREILDKYPELTTEGSPTIQQRLEIANPAVLEMAKKASLNCIQEWGRPAGDITHIVYVSSSEIRLPGGDLYLASQLGLRNDIRRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTSPFLEQECPFLELNYAVQKFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEDNIEEFCKKLMEKSCLDDFNDLFWAVHPGGPAILNRLETKLCLKTDKLDCSRRALMDFGNVSSNTIFYVIEYMREKLKKEKGEEWGLALAFGPGITFEGILMRSL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University