Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Hydrangea quercifolia
Species name
Hydrangea quercifolia is a species of eudicot in the family Hydrangeaceae (hydrangea family).
Species info
Gene sequence info
Hydrangea_quercifolia.4CL.fa
Download
>Hyque.01G232900.1.v1.1
MEIKTEQSQEFIFRSKLPDIYIPNHLPLHTYCFENISQFSSRPCLINGATDETYSYADVELTARRVAAGLDKIGIQQGDVIMLLLHNSVEFIFAFLGSSFRGSISTTANPFYTPAEISKQAKASKAKLIITQACYVEKLKELGEENDIKIMCTDKQIEGFLHFSELTQADEKDLPAVKINPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHSEDVIMCVLPLFHIYSLNSVLLCALRVGSAMVIMQKFDISKLMELVERYKVTIAPFVPPIVLAIAKSPVGDKYDLSSIRTVISGAAPMGKELEDTLRSKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKAGSCGTVVRNAEMKIVDPDTGVSLPRSQAGEICIKGNQIMKGYLNDPEATKSTIDEEGWLHTGDIGYIDEDDEIFIVDRLKELIKYKGFQVAPAELEAMLIANPNISDAAVVPMKDEIAGEVPVAFVVRANGSKISEDEIKQYISQQVVFYKRINRVFFTDTIPKAPSGKILRKDLRARLAAGIPN
>Hyque.02G126100.1.v1.1
MGTHIQNLAQNEEHIFKSLYPSVPVPDNVTLPEFVLRDSELYADNVAFVEAVTGKEYTHGQVVRDTRRFAKALRSLGLRKGRVVVVVLPNVAEYAIVALGIMAAGGVFSGVNPSAHASEIKKQVEAADAKLIVTDMPNYDKAKDLGLPVIVLGKERVESAIYWDELLEAADRASTDTITETVLQTDLCALPFSSGTTGVSKGVMLTHRNLVANLCSTLFSVGPELIGLVTVLGLMPFFHIYGMTGICCATLKNKGKVVVMGRYELETFLKALIEHEVTFAPIVPPIILALVNNPIVDKYDLGKLKLRSIMTAAAPLAPEILSAFLKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHHFAKRNSVGFILPNMELKFIDPETGRSLPRNSHGEIYVRSQCVMKGYYKNEEETAQTIDENGWLHTGDIGYIDDDGDVFIVDRIKEMIKYKGFQSFLYQTQHKCLCSNMLMNQVAPAELEGILLTHPSVKDAAVVGLPDEEAGEIPAACVVMIKDAKEREEEIMNFVASNVANYKRVRMLQFVDSIPTSPSGKIMRRLLKEEMVKKLKNNPKKSYHL
>Hyque.02G004100.1.v1.1
METKSKPQDTIFRSKLPDIYIPKHLSLHSYCFENISEFSSRPCLIKGSTGEIFTYADVELTSRKVAAGLVKLGVKQYNTIMILLPNSPEFVFAFLGASFIGAISTMANPFFTPAEVVKQAKASNSKIIITEACHVEKVREFASENDVKIVCVDSAPAGCLHFSELTRSDEQLLPEVEINSNDVVALPYSSGTTGMPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVLMCVLPLFHIYSLNSILLCGLRVGAAILIMQKFEIVSFLEMIQKYKVTIGPFVPPLVLAMAKSPIVENYDLTSIRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGLSLTRSQPGEICIRGDQIMRGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLTHPNISDAAVVPKKDEAAGEVPVAFVVRSNGSEITEDEIKQYISKQVVFYKRIKRVFFTEAIPKAPSGKILRKDLRARLAAGLHS
>Hyque.08G129300.1.v1.1
MAAKPYYGNDGIYRSPRRPVSLPSDPNLSMVPFLFRNLSSLHNTLALIDADTAETLTFSQLRTTIFKLSQSFLNLNVAKNDVVLIFAPNSIHFLVSFLAVVSIGAVVTTVNPQYTVAEISKQVKDSNPKLVITIHELYDKIKLFNLPSIILSPKNPLQNPIIKPSVWYYSDLINSGGSTPVFPTVVQSDTAALLYSSGTTGTSKGVVLTHRNFIASALMVTSDQDFYGDPKNVFLCFLPMFHIFGLSVLSFAQLQRGNTVVSMANFELGKFLEAIERYRVTHVFVVPPVVIALAKYVEVVKKYDLSSLKEIGSGAAPLGKDLMKDCAKNFPQAVVYQGYGMTETCGIISLENPRTGSRHSGSSGVLVPGVESQIVSVETLKPLPPNQLGEIWVRGSNMMQGYFNNPQATMLTINKQGWLRTGDLGYFDEEGQLYVVDRIKELIKCKGFQVAPAELEGLLLSHPEILDSVVIPFPDAEAGEVPIAYVVRSTTSSLTEEEVQKFMANQVAPFKRLRRVTFVDCVPKSASGKILRRELIQKVRSNL
>Hyque.14G117400.1.v1.1
MISVAASLETQKPDQLISTTTNLVVQNPPSSSHDHDDQHNHEDSHIYKSKLPNIPIPHHIPLHTYCFEKISEFSDRTCLIFGTNGKTYSFSETHLICKKTAAGLSKMGIRKGDVIMILLQNCPEFVFSFMGASMIGAVTTTANPFCTSSEIFKQFNASKPKLIITQSQYVHKLIDSGADYPKIGEDFSVITVDDPPPPPSPGNYCCIHFSELLVLVSSEDRDHESQVVVCSNIEPDEPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLREKDLVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGAVLELIQRHRVSVAAVVPPLVLALAKNPMVAAFDLTSIRMVLSGAAPLGKELEEALQTRLPQAIFGQGYGMTEAGPVLSMSLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLPRNQPGEICIRGSQIMKGYLNDPEATARTIDVDGWLHTGDIGYVDDDEEVYIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVYFVHAIPKSPAGKILRKNLRAKLASPSTLP
>Hyque.14G063700.1.v1.1
MLTCDQEQVGEKDGVFLCVLPMFHVFGLVDIMYAQLQAGNAVVSMEKFEIEMLLKVIEKYKVTNLWVVPPIMIAMVKQSKVQSFDLLSIKRIGSGAAPLGKDLIQECGKNFPHAVVFQGYGMTETCGIVSIENSYVGPRHSGSAGTLAPGVESQIVHVETMKPLPPNQLGEIWVRGPNMMQGYLNDLEATKLTIDKQGWVHSGDLGCFDEHGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPCPDAEAGEVPIGYVVRSPNSSLTEEQVQKFIANQVAPFKRLRRVRFINSVPKSASGKILRRELIAKVRSNL
>Hyque.16G030200.1.v1.1
MEKSGYGRDAIFRSLRPPLPLPRDPNLSMVSFLFRNSSSFPDKPALIDADTAETLTFAQFKSTVSKVSHGLTQLGIKKNDVVLIFAPNSIQYPLCFFGIIAIGAIATTVNPIYTVSELSKQIKDCNPKLIITVPQLLEKTQVFDLPILILGGSESETLRTQNSRITLFTDLIKNSGSVSDFPRVSIKQSDTAALLYSSGTTGTSKGVILSHRNFIAAALMVTSDQELAGEMHNVFLCVLPMFHVFGLAVITYSQLQRGNAVVSMGRFDLQMILRMVEKYRVTHLWVVPPIILALAKQSVVRKYDLSSLKQIGSGAAPLGRELMEECAKNFPHAVVCQGYGMTETCGIAAVENPYMGPRHSGSAGTLVPGIESQIVSVASVKPLPPNQLGEIWVRGPNMMQGYFNNSEATKLTIEKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGYQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIADQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRAKL
MEIKTEQSQEFIFRSKLPDIYIPNHLPLHTYCFENISQFSSRPCLINGATDETYSYADVELTARRVAAGLDKIGIQQGDVIMLLLHNSVEFIFAFLGSSFRGSISTTANPFYTPAEISKQAKASKAKLIITQACYVEKLKELGEENDIKIMCTDKQIEGFLHFSELTQADEKDLPAVKINPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHSEDVIMCVLPLFHIYSLNSVLLCALRVGSAMVIMQKFDISKLMELVERYKVTIAPFVPPIVLAIAKSPVGDKYDLSSIRTVISGAAPMGKELEDTLRSKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKAGSCGTVVRNAEMKIVDPDTGVSLPRSQAGEICIKGNQIMKGYLNDPEATKSTIDEEGWLHTGDIGYIDEDDEIFIVDRLKELIKYKGFQVAPAELEAMLIANPNISDAAVVPMKDEIAGEVPVAFVVRANGSKISEDEIKQYISQQVVFYKRINRVFFTDTIPKAPSGKILRKDLRARLAAGIPN
>Hyque.02G126100.1.v1.1
MGTHIQNLAQNEEHIFKSLYPSVPVPDNVTLPEFVLRDSELYADNVAFVEAVTGKEYTHGQVVRDTRRFAKALRSLGLRKGRVVVVVLPNVAEYAIVALGIMAAGGVFSGVNPSAHASEIKKQVEAADAKLIVTDMPNYDKAKDLGLPVIVLGKERVESAIYWDELLEAADRASTDTITETVLQTDLCALPFSSGTTGVSKGVMLTHRNLVANLCSTLFSVGPELIGLVTVLGLMPFFHIYGMTGICCATLKNKGKVVVMGRYELETFLKALIEHEVTFAPIVPPIILALVNNPIVDKYDLGKLKLRSIMTAAAPLAPEILSAFLKKFPGVEVQEAYGMTEHSCITLTHGDPNKGHHFAKRNSVGFILPNMELKFIDPETGRSLPRNSHGEIYVRSQCVMKGYYKNEEETAQTIDENGWLHTGDIGYIDDDGDVFIVDRIKEMIKYKGFQSFLYQTQHKCLCSNMLMNQVAPAELEGILLTHPSVKDAAVVGLPDEEAGEIPAACVVMIKDAKEREEEIMNFVASNVANYKRVRMLQFVDSIPTSPSGKIMRRLLKEEMVKKLKNNPKKSYHL
>Hyque.02G004100.1.v1.1
METKSKPQDTIFRSKLPDIYIPKHLSLHSYCFENISEFSSRPCLIKGSTGEIFTYADVELTSRKVAAGLVKLGVKQYNTIMILLPNSPEFVFAFLGASFIGAISTMANPFFTPAEVVKQAKASNSKIIITEACHVEKVREFASENDVKIVCVDSAPAGCLHFSELTRSDEQLLPEVEINSNDVVALPYSSGTTGMPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVLMCVLPLFHIYSLNSILLCGLRVGAAILIMQKFEIVSFLEMIQKYKVTIGPFVPPLVLAMAKSPIVENYDLTSIRTVMSGAAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGLSLTRSQPGEICIRGDQIMRGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLLTHPNISDAAVVPKKDEAAGEVPVAFVVRSNGSEITEDEIKQYISKQVVFYKRIKRVFFTEAIPKAPSGKILRKDLRARLAAGLHS
>Hyque.08G129300.1.v1.1
MAAKPYYGNDGIYRSPRRPVSLPSDPNLSMVPFLFRNLSSLHNTLALIDADTAETLTFSQLRTTIFKLSQSFLNLNVAKNDVVLIFAPNSIHFLVSFLAVVSIGAVVTTVNPQYTVAEISKQVKDSNPKLVITIHELYDKIKLFNLPSIILSPKNPLQNPIIKPSVWYYSDLINSGGSTPVFPTVVQSDTAALLYSSGTTGTSKGVVLTHRNFIASALMVTSDQDFYGDPKNVFLCFLPMFHIFGLSVLSFAQLQRGNTVVSMANFELGKFLEAIERYRVTHVFVVPPVVIALAKYVEVVKKYDLSSLKEIGSGAAPLGKDLMKDCAKNFPQAVVYQGYGMTETCGIISLENPRTGSRHSGSSGVLVPGVESQIVSVETLKPLPPNQLGEIWVRGSNMMQGYFNNPQATMLTINKQGWLRTGDLGYFDEEGQLYVVDRIKELIKCKGFQVAPAELEGLLLSHPEILDSVVIPFPDAEAGEVPIAYVVRSTTSSLTEEEVQKFMANQVAPFKRLRRVTFVDCVPKSASGKILRRELIQKVRSNL
>Hyque.14G117400.1.v1.1
MISVAASLETQKPDQLISTTTNLVVQNPPSSSHDHDDQHNHEDSHIYKSKLPNIPIPHHIPLHTYCFEKISEFSDRTCLIFGTNGKTYSFSETHLICKKTAAGLSKMGIRKGDVIMILLQNCPEFVFSFMGASMIGAVTTTANPFCTSSEIFKQFNASKPKLIITQSQYVHKLIDSGADYPKIGEDFSVITVDDPPPPPSPGNYCCIHFSELLVLVSSEDRDHESQVVVCSNIEPDEPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLREKDLVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGAVLELIQRHRVSVAAVVPPLVLALAKNPMVAAFDLTSIRMVLSGAAPLGKELEEALQTRLPQAIFGQGYGMTEAGPVLSMSLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLPRNQPGEICIRGSQIMKGYLNDPEATARTIDVDGWLHTGDIGYVDDDEEVYIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVYFVHAIPKSPAGKILRKNLRAKLASPSTLP
>Hyque.14G063700.1.v1.1
MLTCDQEQVGEKDGVFLCVLPMFHVFGLVDIMYAQLQAGNAVVSMEKFEIEMLLKVIEKYKVTNLWVVPPIMIAMVKQSKVQSFDLLSIKRIGSGAAPLGKDLIQECGKNFPHAVVFQGYGMTETCGIVSIENSYVGPRHSGSAGTLAPGVESQIVHVETMKPLPPNQLGEIWVRGPNMMQGYLNDLEATKLTIDKQGWVHSGDLGCFDEHGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPCPDAEAGEVPIGYVVRSPNSSLTEEQVQKFIANQVAPFKRLRRVRFINSVPKSASGKILRRELIAKVRSNL
>Hyque.16G030200.1.v1.1
MEKSGYGRDAIFRSLRPPLPLPRDPNLSMVSFLFRNSSSFPDKPALIDADTAETLTFAQFKSTVSKVSHGLTQLGIKKNDVVLIFAPNSIQYPLCFFGIIAIGAIATTVNPIYTVSELSKQIKDCNPKLIITVPQLLEKTQVFDLPILILGGSESETLRTQNSRITLFTDLIKNSGSVSDFPRVSIKQSDTAALLYSSGTTGTSKGVILSHRNFIAAALMVTSDQELAGEMHNVFLCVLPMFHVFGLAVITYSQLQRGNAVVSMGRFDLQMILRMVEKYRVTHLWVVPPIILALAKQSVVRKYDLSSLKQIGSGAAPLGRELMEECAKNFPHAVVCQGYGMTETCGIAAVENPYMGPRHSGSAGTLVPGIESQIVSVASVKPLPPNQLGEIWVRGPNMMQGYFNNSEATKLTIEKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGYQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIADQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRAKL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University