Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Hordeum vulgare
Species name
Barley (Hordeum vulgare) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Hordeum_vulgare.CHS.fa
Download
>HORVU1Hr1G064330.1.r1
RNGEACSGMARYHAPRATIMGIGTAVPPNVLRQVSFPDYYFDVTNSNHLVDLKAKFAKICEKTMIEKRHFAMSSDFMRSNPSITAYKSPSLNLRQGLADATIPKLGAEAARDAIRDWGRQASDVTHLVFCTTSSGCLPSADFELTKLVGLPLSVRRFMLYQVGCHGGGMALRLAKDLAENNGGARVLVVCSEVITLALRGPSGVHIENLVGQALFGDGAGAVLVGAEPVGDERPIFEMVSAWQDVIPGTEEMVTAKLLEEGIVYNLHRDIPRHISASMEEVTKKALEQVGDVKERNEEVFWLMHPGGRAILDKVESTLGLRKDKFEVSREVMRQHGNTLSTSVITAMHEMRRRSDKNGLLTAGEGLEWGLLFAFGPGLTIETILLRAPRSPAQIA
>HORVU1Hr1G004830.1.r1
SMAGAVKLEEVRRAQRAVGLATVLAIGTAVPANCVYQATYPDYYFRVTKSDHLADLKEKFERMCEKSTIRKRHMHLTEDILKKHPSLCSHMEPSLDTRHEIVVVEVPKLGKEAAERAIKEWGQPLSKITHVIFCTTSGVDMPGADYQLTRLLGLSPTVKRLMMYQQGCFGGATVLRMAKDIAENNRGARVLIVCSEITAMAFRGPSKSHLDSLVGHALFGDGAAAAIIGADPDEPLEKPLFQLVSASQTILPESEGAINGHLTEAGLTIHLLKDVPGLISQNIEQALEDAFKPLGIHDWNSIFWIAHPGGPAILDMVEEKVGLDMERMRASREVLSEYGNMSSACVLFVLDVMRKSSSHDGHATTGEGKEWGVLFGFGPGLTVETLVLYSAPIVATA
>HORVU1Hr1G004820.1.r1
MAAAVKLEEVRRAQRAVGPATVLAIGTAVPANCVYQATYPDYYFRVTKSEHLSDLKEKFERMCEKSTIRKRHMHLTEDILKKHPSICSHMEPSLNTRHDIVVVEVPKLGKEAAERAIKEWGQPLSKITHVIFCTTSGVDMPGADYQLTRLLGLSPTVKRLMMYQQGCFGGATV
>HORVU1Hr1G089540.1.r1
MAAVRLKEVRMAQRAEGLATVLAIGTAVPANCVYQATYPDYYFRVTKSEHLADLKEKFQRMCDKSMIRKRHMHLTEEILIKNPKICAHMETSLDARHAIALVEVPKLGQGAAEKAIKEWGQPLSKITHLVFCTTSGVDMPGADYQLTKLLGLSPTVKRLMMYQQGCFGGATVLRLAKDIAENNRGARVLVVCSEITAMAFRGPCKSHLDSLVGHALFGDGAAAAIIGADPDQLDEQPVFQLVSASQTILPESEGAIDGHLTEAGLTIHLLKDVPGLISENIEQALEDAFEPLGIHNWNSIFWIAHPGGPAILDRVEDRVGLDKKRMRASREVLSEYGNMSSASVLFVLDVMRKSSAKDGLATTGEGKDWGVLFGFGPGLTVETLVLHSVPVPVPTAASA
>HORVU1Hr1G004840.1.r1
CSSAFTASVVHIRSEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPPPPVQTQMLLGLSPTVKRLMMYQQGCFGGATVLRMAKDIAENNRGARVLVVCSEITAMAFRGPSKSHLDSLVGHALFGDGAAAAIIGADLDEPFEKPLFQLVSASQTILPESEGAINGHXRGGAHHPPSQGRAGAHLSEHRASTRGRLQASGHPRLELHLLDCTSWWAGDP
>HORVU2Hr1G004170.4.r1
TPHDTTICTHSAASGKLRRHTDPPSRSQPSRPLVRTESSMAATMTVEEVRKAQRAEGPATVLAIGTATPANCVYQADYPDYYFKVTKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILQENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHESHLDSLVGQALFGDGAAAVIIGADPDVSVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEDAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHTTTGEGMDWGVLFGFGPGLTVETVVLHSVPVTA
>HORVU2Hr1G005220.3.r1
MAAATMTVEEVRKAQRAEGPATVLAIGTATPANCVYQADYPDYYFKVTKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILQDNPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSRITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHESHLDSLVGQALFGDGAAAVIVGADPDVSVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEDAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHTTTGEGMDWGVLFGFGPGLTVETVVLHSVPITA
>HORVU2Hr1G116390.2.r1
MAATMTVEEVRNAQRAEGPATVLAIGTATPANCVYQADYPDYYFKITKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILEENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHESHLDSLVGQALFGDGAAAVIIGADPDLSVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEEAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHATTGEGMDWGVLFGFGPGLTVETVVLHSVPISAGATA
>HORVU3Hr1G006040.1.r1
MGSQGEVPRVHGQKKAMGTASILAIGTANPSNVLEQSTFPDFYFRVTNSDHKQHLKDKFRRICEKSTIKKRHLYINEALLAANPEMATYMAPSLDMRQAIISEKVPELGAAAATAALKEWGGRIEDITHLIVGSTSGGSDMPGADYHIMRLLGLSPSVRRVALYHQGCFVGAAALRLAKDLAENNGGARVLAVCVETNLMYFRGVDDAHMDNLVCQALFGDGASAIVVGADADPAAEKPLFDVVHATQHLIPETGSAIQGLIREVGLTFGLISEVPSLIAKNIEAGLQDTLDGAGVADGADRNSMFWAVHPGGRAILDKVEAALGLEPEKMRASRKVLAEYGNMGSACAWFVLDEIRRWSAAEGCGTTGEGCEWGVLFGFGPGLTMDTVLLRSRAAHT
>HORVU4Hr1G004810.3.r1
EMGDIQSGRRAVIMGIGTAVPPNVLQQSSFPDYYFEITNSNHMVDLKAKFTKLCENTKIEKRPTSSLGTTHHSPPTSLHHLTFVKSSRMQPCRSLVRKLRRMPSLTGAGTCLMSRTWSSAQ
>HORVU5Hr1G000690.2.r1
QQLINPPSCTEIPSFGINPILLYTTMVSARDVDTNKQQQQQQATCLLAPNPGKATILALGHAFPQQLVMQDYVVEGFMRNTNCNDPELKEKLTRLCKTTTVKTRYVVMSEEILKSYPELAQEGLPTMKQRLDISNKAVTQMATEASLACVEAWGGDLSAITHLVYVSSSEARFPGGDLHLARALGLSPDVRRVMLAFTGCSGGVAGLRVAKGLAESCPGARVLLATSETTVAGFRPPSPDRPYDLVGVALFGDGAGAAVVGADPTAVERPLFELHSALQRFLPDTEKTIDGRLTEEGIKFQLGRELPHIIEAHVESFCQKLIKEHPGAAAAEDVPLTYDKMFWAVHPGGPAILTKMEGRLGLDGGKLRASRSALRDFGNASSNTIVYVLENMVEESRRQRMTEAPVLENMVEESRRQRTTEPEMEPECEWGLILAFGPGITFEGILARNLQARIAAN
>HORVU5Hr1G059800.1.r1
GRLTEEGIKFQLGRELPHIIEAHVESFCQKLIKEHPGAAAAEDVPLTYDKMFWAVHPGGPAILTKMEGRLGLDGGKLRASRSALRDFGNASSNTIVYVLENMVEESRRQRMTEAPXXAEHGGGEQAAEDDGAGDGAGVRVGAHTGVRAGD
RNGEACSGMARYHAPRATIMGIGTAVPPNVLRQVSFPDYYFDVTNSNHLVDLKAKFAKICEKTMIEKRHFAMSSDFMRSNPSITAYKSPSLNLRQGLADATIPKLGAEAARDAIRDWGRQASDVTHLVFCTTSSGCLPSADFELTKLVGLPLSVRRFMLYQVGCHGGGMALRLAKDLAENNGGARVLVVCSEVITLALRGPSGVHIENLVGQALFGDGAGAVLVGAEPVGDERPIFEMVSAWQDVIPGTEEMVTAKLLEEGIVYNLHRDIPRHISASMEEVTKKALEQVGDVKERNEEVFWLMHPGGRAILDKVESTLGLRKDKFEVSREVMRQHGNTLSTSVITAMHEMRRRSDKNGLLTAGEGLEWGLLFAFGPGLTIETILLRAPRSPAQIA
>HORVU1Hr1G004830.1.r1
SMAGAVKLEEVRRAQRAVGLATVLAIGTAVPANCVYQATYPDYYFRVTKSDHLADLKEKFERMCEKSTIRKRHMHLTEDILKKHPSLCSHMEPSLDTRHEIVVVEVPKLGKEAAERAIKEWGQPLSKITHVIFCTTSGVDMPGADYQLTRLLGLSPTVKRLMMYQQGCFGGATVLRMAKDIAENNRGARVLIVCSEITAMAFRGPSKSHLDSLVGHALFGDGAAAAIIGADPDEPLEKPLFQLVSASQTILPESEGAINGHLTEAGLTIHLLKDVPGLISQNIEQALEDAFKPLGIHDWNSIFWIAHPGGPAILDMVEEKVGLDMERMRASREVLSEYGNMSSACVLFVLDVMRKSSSHDGHATTGEGKEWGVLFGFGPGLTVETLVLYSAPIVATA
>HORVU1Hr1G004820.1.r1
MAAAVKLEEVRRAQRAVGPATVLAIGTAVPANCVYQATYPDYYFRVTKSEHLSDLKEKFERMCEKSTIRKRHMHLTEDILKKHPSICSHMEPSLNTRHDIVVVEVPKLGKEAAERAIKEWGQPLSKITHVIFCTTSGVDMPGADYQLTRLLGLSPTVKRLMMYQQGCFGGATV
>HORVU1Hr1G089540.1.r1
MAAVRLKEVRMAQRAEGLATVLAIGTAVPANCVYQATYPDYYFRVTKSEHLADLKEKFQRMCDKSMIRKRHMHLTEEILIKNPKICAHMETSLDARHAIALVEVPKLGQGAAEKAIKEWGQPLSKITHLVFCTTSGVDMPGADYQLTKLLGLSPTVKRLMMYQQGCFGGATVLRLAKDIAENNRGARVLVVCSEITAMAFRGPCKSHLDSLVGHALFGDGAAAAIIGADPDQLDEQPVFQLVSASQTILPESEGAIDGHLTEAGLTIHLLKDVPGLISENIEQALEDAFEPLGIHNWNSIFWIAHPGGPAILDRVEDRVGLDKKRMRASREVLSEYGNMSSASVLFVLDVMRKSSAKDGLATTGEGKDWGVLFGFGPGLTVETLVLHSVPVPVPTAASA
>HORVU1Hr1G004840.1.r1
CSSAFTASVVHIRSEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTPPPPVQTQMLLGLSPTVKRLMMYQQGCFGGATVLRMAKDIAENNRGARVLVVCSEITAMAFRGPSKSHLDSLVGHALFGDGAAAAIIGADLDEPFEKPLFQLVSASQTILPESEGAINGHXRGGAHHPPSQGRAGAHLSEHRASTRGRLQASGHPRLELHLLDCTSWWAGDP
>HORVU2Hr1G004170.4.r1
TPHDTTICTHSAASGKLRRHTDPPSRSQPSRPLVRTESSMAATMTVEEVRKAQRAEGPATVLAIGTATPANCVYQADYPDYYFKVTKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILQENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHESHLDSLVGQALFGDGAAAVIIGADPDVSVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEDAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHTTTGEGMDWGVLFGFGPGLTVETVVLHSVPVTA
>HORVU2Hr1G005220.3.r1
MAAATMTVEEVRKAQRAEGPATVLAIGTATPANCVYQADYPDYYFKVTKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILQDNPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSRITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHESHLDSLVGQALFGDGAAAVIVGADPDVSVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEDAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHTTTGEGMDWGVLFGFGPGLTVETVVLHSVPITA
>HORVU2Hr1G116390.2.r1
MAATMTVEEVRNAQRAEGPATVLAIGTATPANCVYQADYPDYYFKITKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILEENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHESHLDSLVGQALFGDGAAAVIIGADPDLSVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEEAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHATTGEGMDWGVLFGFGPGLTVETVVLHSVPISAGATA
>HORVU3Hr1G006040.1.r1
MGSQGEVPRVHGQKKAMGTASILAIGTANPSNVLEQSTFPDFYFRVTNSDHKQHLKDKFRRICEKSTIKKRHLYINEALLAANPEMATYMAPSLDMRQAIISEKVPELGAAAATAALKEWGGRIEDITHLIVGSTSGGSDMPGADYHIMRLLGLSPSVRRVALYHQGCFVGAAALRLAKDLAENNGGARVLAVCVETNLMYFRGVDDAHMDNLVCQALFGDGASAIVVGADADPAAEKPLFDVVHATQHLIPETGSAIQGLIREVGLTFGLISEVPSLIAKNIEAGLQDTLDGAGVADGADRNSMFWAVHPGGRAILDKVEAALGLEPEKMRASRKVLAEYGNMGSACAWFVLDEIRRWSAAEGCGTTGEGCEWGVLFGFGPGLTMDTVLLRSRAAHT
>HORVU4Hr1G004810.3.r1
EMGDIQSGRRAVIMGIGTAVPPNVLQQSSFPDYYFEITNSNHMVDLKAKFTKLCENTKIEKRPTSSLGTTHHSPPTSLHHLTFVKSSRMQPCRSLVRKLRRMPSLTGAGTCLMSRTWSSAQ
>HORVU5Hr1G000690.2.r1
QQLINPPSCTEIPSFGINPILLYTTMVSARDVDTNKQQQQQQATCLLAPNPGKATILALGHAFPQQLVMQDYVVEGFMRNTNCNDPELKEKLTRLCKTTTVKTRYVVMSEEILKSYPELAQEGLPTMKQRLDISNKAVTQMATEASLACVEAWGGDLSAITHLVYVSSSEARFPGGDLHLARALGLSPDVRRVMLAFTGCSGGVAGLRVAKGLAESCPGARVLLATSETTVAGFRPPSPDRPYDLVGVALFGDGAGAAVVGADPTAVERPLFELHSALQRFLPDTEKTIDGRLTEEGIKFQLGRELPHIIEAHVESFCQKLIKEHPGAAAAEDVPLTYDKMFWAVHPGGPAILTKMEGRLGLDGGKLRASRSALRDFGNASSNTIVYVLENMVEESRRQRMTEAPVLENMVEESRRQRTTEPEMEPECEWGLILAFGPGITFEGILARNLQARIAAN
>HORVU5Hr1G059800.1.r1
GRLTEEGIKFQLGRELPHIIEAHVESFCQKLIKEHPGAAAAEDVPLTYDKMFWAVHPGGPAILTKMEGRLGLDGGKLRASRSALRDFGNASSNTIVYVLENMVEESRRQRMTEAPXXAEHGGGEQAAEDDGAGDGAGVRVGAHTGVRAGD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University