Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Hevea brasiliensis
Species name
Rubber tree (Hevea brasiliensis) is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Hevea_brasiliensis.CHS.fa
Download
>rna-XM_021803298.1
MTMVASVEEIRKAQRAQGPATVLAIGTATPSNCVNQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIKKRYMHLNEEILKENPNMCAYWEPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALIVGSDPDTSIERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFSPIGISDWNSIFWIAHPGGPAILDQVEEKLNLKPEKMRATRHVLSEYGNMSSACVLFILDEMRKKSLEEGKVTTGEGLEWGVLFGFGPGLTVETVVLHSVPTERAAH
>rna-XM_021827676.1
MSKTDNNGALGHYPILTRRIPTTGKATILALGKAFPKQLIPQDCLVEGYIRDTKCEDVSIKEKLERLCKTTTVKRRYTVMSKEILDKYPELATEGLPTIKQRLEIANPAVVEMAKEASLACIKEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLKSDVSRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPVINKESPFFELNYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCKKLMSKAGLTDEFNDLFWAVHPGGPAILNRLESTLKLNTGKLECSRRALMDYGNVSSNTIFYVMEYMREELKRKGGEEWGLALAFGPGITFEGILLRNL
>rna-XM_021830394.1
MGSEENVQSDSLKKANPGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPDLKQKLARLCKTTTVKTRYVVMSEEILKKYPELAIEGLPTVKQRLDICNNAVTQMAIEASQICIKNWGRPMSEITHLVYVSSSEARLPGGDLYLARGLGLNPETQRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGTDPVSDIEHPLFELHTAIQNFLPETEKVIDGRLTEEGISFKLARELPHIIEDNVEEFCHKLMGIAGIGEKEYNKLFWAVHPGGPAILNRIEKRLDLQPEKLNASRRALMDYGNASSNTIVYVLEYMIEECFKVKEKNESCEWGLILAFGPGITFEGILARNLTV
>rna-XM_021781704.1
MEFITKALEIHLEIVKHDSRFDYRPPECYNNFWGAFRVDLEKRCRKILKLISREALVEWSVLVASVFSWDSRFSRNLAQKSKWAKILIVCSENMTSSFHAPSDTHLDILVGSAIFADGAAAVIVGADPDTSTERPLFHLVSASQTIIPESNGIVGQTREMGLTYYLSKSVLQVIADNIVEWMTETLGIIKDWNTLFYIVHPGGPTILQGLEEKLGLEKQKLRASRHVLSENGNMWSPSALFILDEMRKTSMEEGKATTGEGLDLGILFGFGPGLTVDTVIGRSVVIPRG
>rna-XM_021789521.1
MAASVEEIRKAQRAQGTATILAIGTATPSNCVNQADYPDFYFRITKSEHMTELKEKFKRICDKSMIKKRYMHLDEEILKENPNMCAYWEPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLDLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITALFFRGPSDNHFDSLVGQALFGDGAGALIVGSDPDTSIEHPLFQLVSASQTIIPDSDGALDLHLREVGLTFHLLREVPELISKNIEKSLAEAFSPIGISDWNSIFWIAHPGGPAILNQVEAKLSLKPEKMRASRHVLSEYGNMTSACVLFILDEMRKKSLEEGKVTTGEGLEWGVLFGFGPGLTIETVVLHSIPTEMAAQ
>rna-XM_021791649.1
MAASVEDIRKAQRAQGPATILAIGTATPSNCVNQADYPDYYFRITKSEHLTELKEKFKRMCDKSMIKKRYMHLNEQILKENPNMCAYWESSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALVVGSDPDTSIERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGISDWNSIFWIAHPGGPAILDQVEAKLSLKPEKMRSTRHVLSEYGNMSSACVLFILDEMRKKSLEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSVPIESATQ
>rna-XM_021793037.1
MVTVEEVRKAQRAAGPATVLAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMHLTEDILKENPNICAYMAPSLDARQDIVVVEIPKLGKEAAVRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQSLFGDGAAAIIVGSDPVPQVEKPLFELVTAAQTILPNSDGAIDGHLREVGLTFHLLRDVPGIISRNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGLKSTGEGLEWGVLFGFGPGLTVETVVLHSVAT
MTMVASVEEIRKAQRAQGPATVLAIGTATPSNCVNQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIKKRYMHLNEEILKENPNMCAYWEPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALIVGSDPDTSIERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFSPIGISDWNSIFWIAHPGGPAILDQVEEKLNLKPEKMRATRHVLSEYGNMSSACVLFILDEMRKKSLEEGKVTTGEGLEWGVLFGFGPGLTVETVVLHSVPTERAAH
>rna-XM_021827676.1
MSKTDNNGALGHYPILTRRIPTTGKATILALGKAFPKQLIPQDCLVEGYIRDTKCEDVSIKEKLERLCKTTTVKRRYTVMSKEILDKYPELATEGLPTIKQRLEIANPAVVEMAKEASLACIKEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLKSDVSRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPVINKESPFFELNYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCKKLMSKAGLTDEFNDLFWAVHPGGPAILNRLESTLKLNTGKLECSRRALMDYGNVSSNTIFYVMEYMREELKRKGGEEWGLALAFGPGITFEGILLRNL
>rna-XM_021830394.1
MGSEENVQSDSLKKANPGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPDLKQKLARLCKTTTVKTRYVVMSEEILKKYPELAIEGLPTVKQRLDICNNAVTQMAIEASQICIKNWGRPMSEITHLVYVSSSEARLPGGDLYLARGLGLNPETQRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGTDPVSDIEHPLFELHTAIQNFLPETEKVIDGRLTEEGISFKLARELPHIIEDNVEEFCHKLMGIAGIGEKEYNKLFWAVHPGGPAILNRIEKRLDLQPEKLNASRRALMDYGNASSNTIVYVLEYMIEECFKVKEKNESCEWGLILAFGPGITFEGILARNLTV
>rna-XM_021781704.1
MEFITKALEIHLEIVKHDSRFDYRPPECYNNFWGAFRVDLEKRCRKILKLISREALVEWSVLVASVFSWDSRFSRNLAQKSKWAKILIVCSENMTSSFHAPSDTHLDILVGSAIFADGAAAVIVGADPDTSTERPLFHLVSASQTIIPESNGIVGQTREMGLTYYLSKSVLQVIADNIVEWMTETLGIIKDWNTLFYIVHPGGPTILQGLEEKLGLEKQKLRASRHVLSENGNMWSPSALFILDEMRKTSMEEGKATTGEGLDLGILFGFGPGLTVDTVIGRSVVIPRG
>rna-XM_021789521.1
MAASVEEIRKAQRAQGTATILAIGTATPSNCVNQADYPDFYFRITKSEHMTELKEKFKRICDKSMIKKRYMHLDEEILKENPNMCAYWEPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLDLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITALFFRGPSDNHFDSLVGQALFGDGAGALIVGSDPDTSIEHPLFQLVSASQTIIPDSDGALDLHLREVGLTFHLLREVPELISKNIEKSLAEAFSPIGISDWNSIFWIAHPGGPAILNQVEAKLSLKPEKMRASRHVLSEYGNMTSACVLFILDEMRKKSLEEGKVTTGEGLEWGVLFGFGPGLTIETVVLHSIPTEMAAQ
>rna-XM_021791649.1
MAASVEDIRKAQRAQGPATILAIGTATPSNCVNQADYPDYYFRITKSEHLTELKEKFKRMCDKSMIKKRYMHLNEQILKENPNMCAYWESSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAGALVVGSDPDTSIERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFTPIGISDWNSIFWIAHPGGPAILDQVEAKLSLKPEKMRSTRHVLSEYGNMSSACVLFILDEMRKKSLEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSVPIESATQ
>rna-XM_021793037.1
MVTVEEVRKAQRAAGPATVLAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMHLTEDILKENPNICAYMAPSLDARQDIVVVEIPKLGKEAAVRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQSLFGDGAAAIIVGSDPVPQVEKPLFELVTAAQTILPNSDGAIDGHLREVGLTFHLLRDVPGIISRNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGLKSTGEGLEWGVLFGFGPGLTVETVVLHSVAT
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University