Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Herrania umbratica
Species name
Herrania umbratica is a species of eudicot in the family Malvaceae (mallow family).
Species info
Gene sequence info
Herrania_umbratica.CHS.fa
Download
>rna-XM_021425355.1
MNRSGNGVIKQNHLPKPREQNPWLVSSTPRHXXGLLKMSKADSNGAPRHRLRRSSTSGKATVLAMGKAFPSQLIPQECLVEGYIRDTKCEDASIKEKLERLCKTTTVKTRYTVMCKEILDKYPELATEGSSTIKQRLEIANPAVVGMALEASLACIKEWGRAATDITHIIYVSSSEIRLPGGDLYLASQLGLKNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTDPITNSESPFMELNYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLVSKANLTEFNDLFWAVHPGGPAILNRLENTLKLNNGKLECSRRALMDYGNVSSNTIFYVMEYMREELKTEGGEEWGLALAFGPGITFEGILLRSL
>rna-XM_021426422.1
MALPENFGRQKQAQSTATILSIGTANPAFCISQIDYPNYYFRVTKSEHMTQLKGKFKQICEKSMIRKRHFVLTEEILKKNASISTYNDPSLDVRREIAFAQVPKLAMEAASKAIQEWGQPKSQITHLIFSSLSGMDMPGADYHLTELLGLPSSVKRIMLNFQPRYASGTILRMAKDIAENNAGARILVVSTEISIGAFHGPNEHDIASLIGQAIVGDGAAAMIVGADPDVLKERPLFLIVSTAQNIIPGSVGAIEGHVREAGYSIQLSKDVPKLIANNLESCLAEALSPISINDWNSFFWIVHPGGSAILDQIEIKLGLKKEKLLATRHVLSEFGNMSVACVLFILDEMRKKSLEKGKATTGEGLEWGLLIGLGSGITVETVVLRSFPITITHP
>rna-XM_021426427.1
MALPENFGRRKPAQSLATILSIGKAVPTYCISQADYPDYYFRVTKSEHMIQLKEKFKRICEKSMISKRHFVLTEEIINKNPNISTYSSPSLDIRQQILAAEVPKLAMEAASKAIQEWGQPKSQITHLIFSAISGVDMPGADYRLTKLLGLPSSVKRVMTYFQGCYAGGAILRMAKDIAENNAGSRVLVVSSEVLLGIFRAPNEHDTPSLVGNAMLGDGAAAMIIGADPNSLRERPLFQIVSASENIVPDSDGAIEGHMYEAGLSIHLSRDVPKLIADNINKCLAEALSPISNNDWNSFFWIVHPGGNAILDQIETKLELKREKLLTTRHVLSEFGHMSSATVLFILDEMRRRSMEAGKATTAEGLEWGILLGLGAGITVDTVVLRSFPTNTTH
>rna-XM_021426183.1
MAFPENLGRRKPAQRLATILSIGKATPAHCISQTDYLDYYFRVTKNKHMTQLKEKFKHICEKSMISKRHFVLTEEIINKNPNISTYSSPSIDIRQQILAAEVPKLAMEAASKAIQEWRQPKSQITHLIFSAVSGKEMPGADYRLAKLLGLPSVKRVMMYFQGCFAGGTILRIAKDIAENNAGARVLVLSSDITLPTFRAPNEHGIPSLISNAIMGDGAAAMIIGADPNVLKERPLFQIVASTENIIPDSEGAIKGHMHEAGLSIHLSRDVPKLIANNIDKCLAEALSPISINDWNSFFWIVHPLGNAVLDQIEIKLGLKKEKLIETRHVLREFGNVSSATVFFILDEMRRRSMEVGKATTGEGLQWGILFGLGASITVETVVLRSFPTNTQLIQGKE
>rna-XM_021428179.1
MASEKNLETHQAEGLVTILAIGTTNPPHCFYQVDYSDFYFRVTKREHKIELKDKFKRICERSSIKKRYMHLTEDIIKENPNLIIYKAPSFDARQDILVTEVPKLGKEAALKAIKEWGQPISKITHLIFCTSSGINMPSADHQLARLIGLKPSVQKFMIYQQGCFAAGTALRLSKDLAKNNAGARVLIVCSELMVECFQPPSETHLDILVGSALFSDGAAAVIVGANPDTTINERPLFQIVSAHQTIIPDSADKIVAKIREMGMEYYLSRVPRCIANNIEQCLIEALIPFGIGDWKTLFYIVHPGGPAVLRGVEEKLGLDREKLKASWHVLSEYGNMWSPSVLFVLDEMRKMSILEGKATAGEGLEWGVLFGFGPGLTVETVVLRSFALNSHP
>rna-XM_021430455.1
MGMGEEAQEGFATMANPGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPELKRKLSRLCKTTTVKTRYVVMSDEILKKYPELAIEGLPTVKQRLDICNNAVTEMAIEASRACIKKWGRPISDITHLVYVSSSEARLPGGDLFLAKGLGLSPETQRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPVLSIERPLFELHTAMQNFLPNTEKTIDGKLTEEGISFKLARELPQIIEDNVEGFCEKLMGIVGLTDKDYNNMFWAVHPGGPAILNRMEKRLDLFPEKLNASRRALMDYGNASSNTIVYVLEYMIEESLKRKTESREDSEWGLILAFGPGVTFEGILARNLTVQE
>rna-XM_021434474.1
MVTVEEVRKAQRAEGPATILAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPMFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEIKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSREDGLKTTGEGLEWGVLFGFGPGLTVETVVLHTISA
>rna-XM_021442205.1
MAMASVEEIRKAQRAQGPATVLAIGTATPPNCVSQADYPDYYFRITNSEHLTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPDTKIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKEHRESLVEALSPIGINDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLKATRHVLSEFGNMSSACVLFILDEMRKQSLEQGKPTTGEGLEWGVLFGFGPGLTVETVVLHSIPTVATH
>rna-XM_021442478.1
MATVEEIRKAQRAEGVATILAIGTATPSNCIFQSDYPDFYFGVTNNNHTTELKHKFKQICDKSMIKKRYMYATEEVLKENPSLCAYMATSLDARQNIAVVEVPKLGKEAATKAIEEWGQPKSKITHLVFGTCSSVDMPGADYRLTKLLGLSPSVKRAIVYHNGCFAGGKALRLAKDLAENNKGARVLVVCSEVLSLFFHGVSDQIEADYLVASAIFGDGAGAAIVGADPDTLIERPLFQLVSSSQTILPNSEGTIEGHLREVGLILRLSKQVPTLITNNIEKNIIEAFNPIGSISNWDSIFYVAHPGAPAILNQLERNLNLNKHKLRASRHVLSEYGNMSSAAVFFVLDEMRNKSVEEGKSTTGEGLEWGVLLAYGPGITTETIVLHSVPIKPSH
MNRSGNGVIKQNHLPKPREQNPWLVSSTPRHXXGLLKMSKADSNGAPRHRLRRSSTSGKATVLAMGKAFPSQLIPQECLVEGYIRDTKCEDASIKEKLERLCKTTTVKTRYTVMCKEILDKYPELATEGSSTIKQRLEIANPAVVGMALEASLACIKEWGRAATDITHIIYVSSSEIRLPGGDLYLASQLGLKNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTDPITNSESPFMELNYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLVSKANLTEFNDLFWAVHPGGPAILNRLENTLKLNNGKLECSRRALMDYGNVSSNTIFYVMEYMREELKTEGGEEWGLALAFGPGITFEGILLRSL
>rna-XM_021426422.1
MALPENFGRQKQAQSTATILSIGTANPAFCISQIDYPNYYFRVTKSEHMTQLKGKFKQICEKSMIRKRHFVLTEEILKKNASISTYNDPSLDVRREIAFAQVPKLAMEAASKAIQEWGQPKSQITHLIFSSLSGMDMPGADYHLTELLGLPSSVKRIMLNFQPRYASGTILRMAKDIAENNAGARILVVSTEISIGAFHGPNEHDIASLIGQAIVGDGAAAMIVGADPDVLKERPLFLIVSTAQNIIPGSVGAIEGHVREAGYSIQLSKDVPKLIANNLESCLAEALSPISINDWNSFFWIVHPGGSAILDQIEIKLGLKKEKLLATRHVLSEFGNMSVACVLFILDEMRKKSLEKGKATTGEGLEWGLLIGLGSGITVETVVLRSFPITITHP
>rna-XM_021426427.1
MALPENFGRRKPAQSLATILSIGKAVPTYCISQADYPDYYFRVTKSEHMIQLKEKFKRICEKSMISKRHFVLTEEIINKNPNISTYSSPSLDIRQQILAAEVPKLAMEAASKAIQEWGQPKSQITHLIFSAISGVDMPGADYRLTKLLGLPSSVKRVMTYFQGCYAGGAILRMAKDIAENNAGSRVLVVSSEVLLGIFRAPNEHDTPSLVGNAMLGDGAAAMIIGADPNSLRERPLFQIVSASENIVPDSDGAIEGHMYEAGLSIHLSRDVPKLIADNINKCLAEALSPISNNDWNSFFWIVHPGGNAILDQIETKLELKREKLLTTRHVLSEFGHMSSATVLFILDEMRRRSMEAGKATTAEGLEWGILLGLGAGITVDTVVLRSFPTNTTH
>rna-XM_021426183.1
MAFPENLGRRKPAQRLATILSIGKATPAHCISQTDYLDYYFRVTKNKHMTQLKEKFKHICEKSMISKRHFVLTEEIINKNPNISTYSSPSIDIRQQILAAEVPKLAMEAASKAIQEWRQPKSQITHLIFSAVSGKEMPGADYRLAKLLGLPSVKRVMMYFQGCFAGGTILRIAKDIAENNAGARVLVLSSDITLPTFRAPNEHGIPSLISNAIMGDGAAAMIIGADPNVLKERPLFQIVASTENIIPDSEGAIKGHMHEAGLSIHLSRDVPKLIANNIDKCLAEALSPISINDWNSFFWIVHPLGNAVLDQIEIKLGLKKEKLIETRHVLREFGNVSSATVFFILDEMRRRSMEVGKATTGEGLQWGILFGLGASITVETVVLRSFPTNTQLIQGKE
>rna-XM_021428179.1
MASEKNLETHQAEGLVTILAIGTTNPPHCFYQVDYSDFYFRVTKREHKIELKDKFKRICERSSIKKRYMHLTEDIIKENPNLIIYKAPSFDARQDILVTEVPKLGKEAALKAIKEWGQPISKITHLIFCTSSGINMPSADHQLARLIGLKPSVQKFMIYQQGCFAAGTALRLSKDLAKNNAGARVLIVCSELMVECFQPPSETHLDILVGSALFSDGAAAVIVGANPDTTINERPLFQIVSAHQTIIPDSADKIVAKIREMGMEYYLSRVPRCIANNIEQCLIEALIPFGIGDWKTLFYIVHPGGPAVLRGVEEKLGLDREKLKASWHVLSEYGNMWSPSVLFVLDEMRKMSILEGKATAGEGLEWGVLFGFGPGLTVETVVLRSFALNSHP
>rna-XM_021430455.1
MGMGEEAQEGFATMANPGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPELKRKLSRLCKTTTVKTRYVVMSDEILKKYPELAIEGLPTVKQRLDICNNAVTEMAIEASRACIKKWGRPISDITHLVYVSSSEARLPGGDLFLAKGLGLSPETQRVMLYFMGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPVLSIERPLFELHTAMQNFLPNTEKTIDGKLTEEGISFKLARELPQIIEDNVEGFCEKLMGIVGLTDKDYNNMFWAVHPGGPAILNRMEKRLDLFPEKLNASRRALMDYGNASSNTIVYVLEYMIEESLKRKTESREDSEWGLILAFGPGVTFEGILARNLTVQE
>rna-XM_021434474.1
MVTVEEVRKAQRAEGPATILAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPMFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEIKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSREDGLKTTGEGLEWGVLFGFGPGLTVETVVLHTISA
>rna-XM_021442205.1
MAMASVEEIRKAQRAQGPATVLAIGTATPPNCVSQADYPDYYFRITNSEHLTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPDTKIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKEHRESLVEALSPIGINDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLKATRHVLSEFGNMSSACVLFILDEMRKQSLEQGKPTTGEGLEWGVLFGFGPGLTVETVVLHSIPTVATH
>rna-XM_021442478.1
MATVEEIRKAQRAEGVATILAIGTATPSNCIFQSDYPDFYFGVTNNNHTTELKHKFKQICDKSMIKKRYMYATEEVLKENPSLCAYMATSLDARQNIAVVEVPKLGKEAATKAIEEWGQPKSKITHLVFGTCSSVDMPGADYRLTKLLGLSPSVKRAIVYHNGCFAGGKALRLAKDLAENNKGARVLVVCSEVLSLFFHGVSDQIEADYLVASAIFGDGAGAAIVGADPDTLIERPLFQLVSSSQTILPNSEGTIEGHLREVGLILRLSKQVPTLITNNIEKNIIEAFNPIGSISNWDSIFYVAHPGAPAILNQLERNLNLNKHKLRASRHVLSEYGNMSSAAVFFVLDEMRNKSVEEGKSTTGEGLEWGVLLAYGPGITTETIVLHSVPIKPSH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University