Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Herrania umbratica
Species name
Herrania umbratica is a species of eudicot in the family Malvaceae (mallow family).
Species info
Gene sequence info
Herrania_umbratica.4CL.fa
Download
>rna-XM_021445422.1
MITTLFQFHILLKHRPVSFLMLLSIMGTPTAIQHLEDNGEHCFGSKYPSVPVPDNLTLPEFVLQDADLYADKVAFVEAVSGKAYTYHDVVRDTGRFGKALRSIGLKKGDVVIVLLPNIAEYGIVALGIMAAGGVFSGANPASHASEIKKQADAANAKMLVTNGPNYEKAKGLELPVIVLGEERIESAMNWDDLLKAAENAGECTRFTKEEVVQSDLCALPFSSGTTGVSKGVMLTHRNLVANLCSSLFSVGQELVGQVTTLGLIPFFHIYGITGICCATLRNKGKVVMMNRFDLRTFLNALITQEVTFAPVVPPIILALVKNPIVEEFDLSKLKLRAILTAAAPLAPELLTAFENKFPGVQVQEAYGLTEHSCITLTHGDPIKGHGIAKKNSVGFILPNLEIKFIDPDTGRSLPKNIPGELCVRSQCVMQGYYKNKEETDRTIDKNGWLHTGDIAYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVPLPDEGAGEIPAACVVMSPNATESETDIMDYVASNVAHYKKVRALQFVETIPKSPSGKIMRRLLKEKMMEKMGKNIPTANATLPA
>rna-XM_021420562.1
MEANQEQQEFIFRSRLPDVYIPNHLPLQTYCFEKISQFKDHPCLINGPNGRIYSYAEVELTARRVATGLNNLGIQQGDVIMLLLQNSPEFVFAFLGASFLGAISTTANPFYTPAEIVKQATASKTRLLITQAVYAEKVKNFAKENDIKIITIDTPPEGCMHFSELTQADESEIPPVKINPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGENPNLYFHEKDVILCVLPLFHIYSLNSVLLCSLRVGAAILIMQKFEIVTLMELVQKYKVTIAPLVPPIVLAIAKTPDVDKYDLSSIRTVMSGAAPMGKELEDAVRARLPNAKLGQGYGMTEAGPVLAMNLAFAKQACETKSGSCGTVVRNAEMKIVNPDTGASLPRNQSGEICIRGSQIMKGYLNDPEATQRTIDKDGWLHTGDVGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIGHPNIFDAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQFISKQVVFYKRLGQVFFTEAIPKAPSGKILRKDLRARLASDIPK
>rna-XM_021423492.1
MEKSGYGRDGIFRSLRPPLVLPKDPNLSMVSFLFRNVSSYPDKPALIDADTDETLSFSEFKSAVIKLSHAFLNLGINKNDRVMIFAPNSIQYPLCFFAVTAIGAIATTANPIYTVNELSKQIKDSIPKLVVTVPELFEKVKDFNLPVIFLGSERNQQPYDPKDIPKILSFHDLLGLAGNVTEFPAVSVKQTDTASLLYSSGTTGVSKGVVLTHRNFIAASLMVTMDQELAGDMHRVFLCVLPMFHVFGLAVITYGQLQKGNALVSMAKFDFGMFLRNVEKYRATHLWVVPPIVLAMAKQSVVKNFDLSSLRQIGSGAAPLGKELMEECARNFPQAVVLQGYGMTETCGIVSVENPNVGARHTASTGMLASSIEAQIVSTETLKPLPPNQLGEIWVRGPNMMQGYFNNPQATKLTIDGKGWVHTGDLGYFDEDGNLYVVDRIKELIKYKGFQIAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYIVRSPNSSLTEVDVQNFIAKQVAPFKRLRRVTFISNVPKSASGKILRRELVEKVRSKI
>rna-XM_021427135.1
MISIADPVEPQKPELSPSLSPPATKPSSETTGDHVFRSKLPDIPISNHLPLHTYCFENLSSFPDKPCLISGSSGKTYSFSETHLIARKTAAGLSNLGIRKGDVIMILLQNCAEFVFSFMGASMIGAVSTTANPFYTPTEIFKQYKAAQAKLIVTQSQYVDKLKDTSNNENFPKIGEDFKVITIDDPPENCLHFTVLSEANENEIPQVSIDPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKHDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPMVAQYDLSSIRVVLSGAAPLGKELEEALRGRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGFSLDYNQPGEICIRGSQIMKGYLNDTSSTATTIDVEGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELESLLVSHPSIADAAVVPQKDEVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVHFVHAIPKSPAGKILRKDLRAKLAAATTLP
>rna-XM_021433952.1
MFRYLFCTKERYKLRKMKSNLINLLSYFWQVVSTPLYNYLYILSQTSFKSSKKQASQRADPISCKQTLAMEKSFNPKTRTYNSPRPPIKLPTNPELSLTSFILESTSSIPHETALIDSSNSNETLTFLQLKAQVSSLAYALHHQFHIAKSDVVLILAPNSIRFPISFLAIISLGAIATTANPSFTFNEISKQVNDCRPKLIITIPELYSKVHHFNVPLIFLQSSSHSTNFFLDYSANPKFSYYSDVVENYTPPSNFRPYVVRQNDVAALMYSSGTTGTSKGVMLTHKNFIASSLNFTADQDRYNEGRVVCLCFLPMFHGFGSVLSFAQLRRGNVLVSMAKFELEKVLAAVEKFGVTLLFAVPPVMVSLAKRGEVKEHDLSSLRQIISSAAPLSRDLIETCAKNLPHVEIFQGYGMTEACGKISLENPKEGRRFSGSTGTLMPVIESKIVSVNTMKPLPPHQIGEIWIRGPTIMQGYFNNPEATKLAMDEQGWLRTGDLGYFDEQGQLFVVDRIKELIKCNGFQVAPAELEGLLLSHPEIVDVVVIPFPDVKAGEVPIAYIVRAPDSSLNEDDVKIFIAEKVAPYKRLRRVTFLSSVPRSVSGKILRRELIQKVRSKI
>rna-XM_021439014.1
MAPQAELQQEEIIYRSKLPDIYIPKHLPLHSYCFQNISKVASRPCLINGTTGKVYTYAEVELTARRVASGLNKLGIHQRQVIMLLLPNTPEFVLSFLGASYLGAIATAANPFFTPAEVSKQAKASNARLIITQACYLDKVKEFAEDNDVKIMCIDSAPEGYLHFSELTQADEHDLPEVDIVPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVILCTLPMFHIYALNSIMLCGLRVGAAILIMQKFEIGLLLELIQKYKVTIAPIVPPIVLAIAKSSETEKYDLSSVRMLKSGAAPLGKELEDAVRAKFPGAKLGQGYGMTEAGPVLAMCLGFAREPFEIKSGACGTVVRNAEMKIVDPDTGSSLPRNQAGEICIRGDQIMKGYLNDPEATARTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPDIIDAAVVAMKDEAAGEVPVAFVVRSGNSQLCEDEIKQYISKQVVFYKRISRVFFIEAIPKAPSGKILRKELRAKLATGNY
MITTLFQFHILLKHRPVSFLMLLSIMGTPTAIQHLEDNGEHCFGSKYPSVPVPDNLTLPEFVLQDADLYADKVAFVEAVSGKAYTYHDVVRDTGRFGKALRSIGLKKGDVVIVLLPNIAEYGIVALGIMAAGGVFSGANPASHASEIKKQADAANAKMLVTNGPNYEKAKGLELPVIVLGEERIESAMNWDDLLKAAENAGECTRFTKEEVVQSDLCALPFSSGTTGVSKGVMLTHRNLVANLCSSLFSVGQELVGQVTTLGLIPFFHIYGITGICCATLRNKGKVVMMNRFDLRTFLNALITQEVTFAPVVPPIILALVKNPIVEEFDLSKLKLRAILTAAAPLAPELLTAFENKFPGVQVQEAYGLTEHSCITLTHGDPIKGHGIAKKNSVGFILPNLEIKFIDPDTGRSLPKNIPGELCVRSQCVMQGYYKNKEETDRTIDKNGWLHTGDIAYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVPLPDEGAGEIPAACVVMSPNATESETDIMDYVASNVAHYKKVRALQFVETIPKSPSGKIMRRLLKEKMMEKMGKNIPTANATLPA
>rna-XM_021420562.1
MEANQEQQEFIFRSRLPDVYIPNHLPLQTYCFEKISQFKDHPCLINGPNGRIYSYAEVELTARRVATGLNNLGIQQGDVIMLLLQNSPEFVFAFLGASFLGAISTTANPFYTPAEIVKQATASKTRLLITQAVYAEKVKNFAKENDIKIITIDTPPEGCMHFSELTQADESEIPPVKINPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGENPNLYFHEKDVILCVLPLFHIYSLNSVLLCSLRVGAAILIMQKFEIVTLMELVQKYKVTIAPLVPPIVLAIAKTPDVDKYDLSSIRTVMSGAAPMGKELEDAVRARLPNAKLGQGYGMTEAGPVLAMNLAFAKQACETKSGSCGTVVRNAEMKIVNPDTGASLPRNQSGEICIRGSQIMKGYLNDPEATQRTIDKDGWLHTGDVGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIGHPNIFDAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQFISKQVVFYKRLGQVFFTEAIPKAPSGKILRKDLRARLASDIPK
>rna-XM_021423492.1
MEKSGYGRDGIFRSLRPPLVLPKDPNLSMVSFLFRNVSSYPDKPALIDADTDETLSFSEFKSAVIKLSHAFLNLGINKNDRVMIFAPNSIQYPLCFFAVTAIGAIATTANPIYTVNELSKQIKDSIPKLVVTVPELFEKVKDFNLPVIFLGSERNQQPYDPKDIPKILSFHDLLGLAGNVTEFPAVSVKQTDTASLLYSSGTTGVSKGVVLTHRNFIAASLMVTMDQELAGDMHRVFLCVLPMFHVFGLAVITYGQLQKGNALVSMAKFDFGMFLRNVEKYRATHLWVVPPIVLAMAKQSVVKNFDLSSLRQIGSGAAPLGKELMEECARNFPQAVVLQGYGMTETCGIVSVENPNVGARHTASTGMLASSIEAQIVSTETLKPLPPNQLGEIWVRGPNMMQGYFNNPQATKLTIDGKGWVHTGDLGYFDEDGNLYVVDRIKELIKYKGFQIAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYIVRSPNSSLTEVDVQNFIAKQVAPFKRLRRVTFISNVPKSASGKILRRELVEKVRSKI
>rna-XM_021427135.1
MISIADPVEPQKPELSPSLSPPATKPSSETTGDHVFRSKLPDIPISNHLPLHTYCFENLSSFPDKPCLISGSSGKTYSFSETHLIARKTAAGLSNLGIRKGDVIMILLQNCAEFVFSFMGASMIGAVSTTANPFYTPTEIFKQYKAAQAKLIVTQSQYVDKLKDTSNNENFPKIGEDFKVITIDDPPENCLHFTVLSEANENEIPQVSIDPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKHDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPMVAQYDLSSIRVVLSGAAPLGKELEEALRGRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGFSLDYNQPGEICIRGSQIMKGYLNDTSSTATTIDVEGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELESLLVSHPSIADAAVVPQKDEVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHKVHFVHAIPKSPAGKILRKDLRAKLAAATTLP
>rna-XM_021433952.1
MFRYLFCTKERYKLRKMKSNLINLLSYFWQVVSTPLYNYLYILSQTSFKSSKKQASQRADPISCKQTLAMEKSFNPKTRTYNSPRPPIKLPTNPELSLTSFILESTSSIPHETALIDSSNSNETLTFLQLKAQVSSLAYALHHQFHIAKSDVVLILAPNSIRFPISFLAIISLGAIATTANPSFTFNEISKQVNDCRPKLIITIPELYSKVHHFNVPLIFLQSSSHSTNFFLDYSANPKFSYYSDVVENYTPPSNFRPYVVRQNDVAALMYSSGTTGTSKGVMLTHKNFIASSLNFTADQDRYNEGRVVCLCFLPMFHGFGSVLSFAQLRRGNVLVSMAKFELEKVLAAVEKFGVTLLFAVPPVMVSLAKRGEVKEHDLSSLRQIISSAAPLSRDLIETCAKNLPHVEIFQGYGMTEACGKISLENPKEGRRFSGSTGTLMPVIESKIVSVNTMKPLPPHQIGEIWIRGPTIMQGYFNNPEATKLAMDEQGWLRTGDLGYFDEQGQLFVVDRIKELIKCNGFQVAPAELEGLLLSHPEIVDVVVIPFPDVKAGEVPIAYIVRAPDSSLNEDDVKIFIAEKVAPYKRLRRVTFLSSVPRSVSGKILRRELIQKVRSKI
>rna-XM_021439014.1
MAPQAELQQEEIIYRSKLPDIYIPKHLPLHSYCFQNISKVASRPCLINGTTGKVYTYAEVELTARRVASGLNKLGIHQRQVIMLLLPNTPEFVLSFLGASYLGAIATAANPFFTPAEVSKQAKASNARLIITQACYLDKVKEFAEDNDVKIMCIDSAPEGYLHFSELTQADEHDLPEVDIVPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVILCTLPMFHIYALNSIMLCGLRVGAAILIMQKFEIGLLLELIQKYKVTIAPIVPPIVLAIAKSSETEKYDLSSVRMLKSGAAPLGKELEDAVRAKFPGAKLGQGYGMTEAGPVLAMCLGFAREPFEIKSGACGTVVRNAEMKIVDPDTGSSLPRNQAGEICIRGDQIMKGYLNDPEATARTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPDIIDAAVVAMKDEAAGEVPVAFVVRSGNSQLCEDEIKQYISKQVVFYKRISRVFFIEAIPKAPSGKILRKELRAKLATGNY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University