Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Handroanthus impetiginosus
Species name
Handroanthus impetiginosus is a species of eudicot in the family Bignoniaceae (trumpet creeper family).
Species info
Gene sequence info
Handroanthus_impetiginosus.COMT.fa
Download
>PAC4GC:21707421
MDIKPDEEAGLFAMQLTSGSVLQMVLKTAVELDLLELIKKAGPEATASAAELAAQLPTNNPDAVDMLDRILRLLAAHSVLVCSLKPLPDGSLERRYSLSPVGEFLTRNEDGVSVGSFCLLIQDRVATETWYHLKDAILEGGIPFNRAFGMSPFEYFAKDPKLSRIFDQAMYEESTIILKKILEKYKGFEGLKSLVDVGGGIGASLRMIISKYPSIKGINFDLPHVIQNAPSYPGMEHISGDMFLLLCQKPMRFL
>PAC4GC:21707418
MSAFEYSAKDPRFNQLFNQAMQEESTIIMKKVLEKYKGFEGLKTLVDVGGGIGASLKMIISRYPSIKGINFDLPHVIQNVPSYLVERISSDMFDKLVEFLLRLHVNNYHFNKNWICHDWIDLHCEKLLKNCYEALPESGKVITAENLARGPK
>PAC4GC:21670424
MNPPEKPIKISSNEEDEASQYAMQLVNASVMPMVLKACIELDVFGIISRKGPNAQLSPSQIASQIPCHNPDFATHLLDRMLGLLASYSILMCSVNQEERLYSLAPVSKYFLPNANGASLAPLFQADQDKIVMDTWYHIKDAVIQGESPFKRAYGMNISEYMVKDPNYLQLFRASMSSYNSMFMEKLLETYKGFEGLKSIVDVGGGDGSILKTIIGKYPTIKGINFDIPAVIENTATYPGIEQVAGDMFITIPKGDALFLKWILHSWDDEHCIRILKNCYEAIPDHGKVMLVELVVPEVPESRGDVRSKLQFDMIMMNMNPGGKRRTKREFKTLGEAAGFSSIKVECCVYSFSLVELYK
>PAC4GC:21693635
MENAINGSTNSANIEEDEAFNRASAATASFVLPMALDTAIQLRLFEIISKAGEGAGVLPSDIAAQLPNSGPPEAVASRLDCVLRLLASYSLLTCSVSKVANRGIQTRYGLATAGKFFVRDENGASLVVGLRDFTRYQAGFLETCSKLKDAVLGGGNPFERAYGMPIHEYMKSNPDYRRIFQDFMTNYSVMIMKRVCEKYNGFEGLRSIVNVGGGSGVTLDFIISRYPSIHGINFDLPEVIEGAPSYKGVHHISGDMFVQVPQGDAILLKFILHNWSDDQCLQVLKNCYKALPKTGKVIILDTMLPDIPQDDTHSKMVSQFDYIMLMLYGSRERTKAEFEALAKKSGFSEFKVVCNAHSVWVMEVIKTE
>PAC4GC:21710801
MDNERDEEACLFAMQLTTSSVLPMVLKTAIELDLLELIKKAGPEATASASELAAQLPTNNPGAADMIDRILGLLTAHSVLVCVLKPLPHGGVERRYSLAPVGEFLTRNEDGVSVATTCLMIQDRILMEPWYHLKDAILDGGIPFNRTYGISAFEYLAKDPKFNQIFDQAMYEESTIFMKKILQKYKGFEGLKSLVDVGGGIGASIKMIISKYPSIKGINFDLPHVIQNALSSPGVEHISGDMFVSVPKADAIFMKRILHGWSDSQCEKLLKNCYEALPENGKVIIAEAILPEKPNSGLNYLAAAHANVILLTPGGKERSEKQVEALAKKAGFKKLIKVCSAFSIWIVEFHK
>PAC4GC:21710800
MDNKPDEEACLSAMQLTTSSVLPMVLKTAIELDLLELIKKAGPEASASASELVAQLPTNNPDAADMTDRILRLLVANSILVCSLKLLPDGGVQRRYSPAPVGEFFTRNEDGASMGSTCLLIQDRVLMEPWYHLKDAILEGGIPFNRAYGMSAFEYLTKDLRFNRIFNQAMYEQSTMFMKKILEKYKVFEGLKSLVDVGGGIGASLKMIISKFPSIKGINFDLPHVIQNTPSYPGMEHISGDIFVSVPKADGIFMKVKLNFHIFPRTNYFYDLIFT
>PAC4GC:21710809
MDNKPDEEAYLFVMQLTTGSALPMVLKTAIELDLLELIKKAGPEAPASAAELAAQLPTNNPNSADMIDRILRLLAAHSVLVCSLKPLPEDGIERRYSLTPVGEFLTRNEDGVSMATPCLMIQDRVWMEPWYHLKDAILEGGIPFNRAYGMSAFEYLAKDPRFNRIFNQDMYEESTIFMKKILEKYKGFEGLKSLVDVGGGIGGSLDMIISKYPSIKGINFDLPHVIQTAPSYPGQSEGAIGGNYHHFLSYTLSPALELIVAWISFHYPYYFIPSSILQTNTIKLVYLRFESWKVVQEWSTLVWICHNWSDPHCEKLLKNCYEALPENGKVIIAETILPEDPSSGLSALWATYADVIMLAYIPGGKERSEKEFQTLAKKAGFKQLINVCSAFNIWIMEFHK
>PAC4GC:21699410
MDNKPDEEAYLFARQLTTGLALPMVLKAAVELDLLELIKKAGPEASASASELVAQLPTKNPDAADMIDRILRLLAANSVLVCSLKRLPDGGVERHYSLTPVGEFFTRNEDGASVGSTCLLIQDRVLMEPWYHLKDAILEGGIPFNRAYGMSAFEYPAKDLRFNQVFNQAMYEQSTIFMKKILEKYKGFEGLKSLVDVGGGIGASLKMIISKYPSIKGINFDLPHVIQNAPSYPGMEHISGDMFVSVPKAGAIFMKWICHDWSDSHCEKLLKNCYEALPENGKVIIAETIMPEDPNVGLNSLRAAQSDVIMLAYNPGGKERSEREFETLAKKAGFKQLIKACSAFNIWIIEFHK
>PAC4GC:21700251
MDYNKPAEEACLFAMQLTSGSVLQMVLKTAIELDLLELIKKAGPEATVSASELAVQLPTNNPDAVDMLDRILRLLAAHSVLVCGLKPLPDGGLERRYSLSPVGEFLTRNEDGVSGGTFCLMIQDRVLMEPWYHLKDAILEGGIPFDRAYGMSGFEYLAKDPRLSRIFDQAMYEESTIIMKKILEKYKGFETLKSLVDVGGGIGGTLKMIISKYPSIKGINFDLPHVIRNAPSYPDEEAGLFAMQLTSGSVLQMVLKTAVELDLLELIKKAGPEATASAAELAAQLPTNNPDAVDMLDRILRLLAAHSVLVCSLKPLPDGSLERRYSLSPVGEFLTRNEDGVSVGSFCLLIQDRVATETWYHLKDAILEGGIPFNRAFGMSPFEYFAKDPKLSRIFDQAMYEESTIILKKILEKYKGFEGLKSLVDVGGGIGASLKMIISKYPSIKGINFDLPHVIQNAPSYPADAIFMKWICHNWSDSHCEKLLKNCYEALPENGKVIIADIILPEDPNSGPNSLRSSQMDVIMLANNTGGKERSEREFEALAKKAGFKQLIKVCSAFDIWIMELHK
>PAC4GC:21700257
MSAFEYPAKDSRFNRVFNQSMYEQSTIFMKKILEKYKGFEGLKSLVDVGGGIGASLKMIISKYPSIKGINFDLPHVIQNAPSYPGMEHISGDMFVSVPKADAIFMKWICHDWSDSHCEKLLKNCYEALPENGKVIIAETIMPEDPNSGLNSLRAAQGDVIMLAYNPGGKERSEREFETLAKKAGFKQLIKACSAFNIWIIEFHK
>PAC4GC:21700254
MDNKPDEEACLFAMHLTTSSVLPMILKTAIELDLLELIKKTGAKATASAAELAAQLPRNNPDGADIIDRILRLMVAHSVLVCGLKLLPDGGFFARNEDGLSVGTPCLKIQDGAWMEPW
>PAC4GC:21700255
MENKPYEDACLFAMQLTSGSVLPMVLKTVIELDLLELIKKAGPEAKASAAEIAAQLPTNNPGAAGMIDRILQLLTAHSVLVCELKLLPDGGGVERRYSLSPVGEFLTRNEDGVSVGPTCLMNQDRVFMEPWYHLKDAILEGGIPFNRTYGMSAFEYFAKDPRFSRIFNQSMHEESIIIMKKIVEEYKGFEGLKTLVDVGGGIGASLKMIISKYPSIKGINFDLPYVIQNAPSYPGVEHISGDMFDSVPKADAIFMKWICHDWSDSDCEKLLKNCYEALPENGKVIIAETVLPEKPNTRLNSLQAAHSDVMMLAYTPGGKERSKGEFEVLAKKAGFKQLTIVCSALKIWIMEFHK
>PAC4GC:21700256
MDNKPDEEAYLFALQLATGLALPMVLKTAVELDLLELIKKAGPEASASASELVAHLPTNNPDAADMIDRILRLLAANSVLVCSLKLLPDGGVERRYSLTPVGEFFTRNVDGASVGSTCLLIQDRVLMEP
>PAC4GC:21682788
MDYNKPAEEACLFAMQLTSGSVLQMVLKTAIELDLLELIKKAGPEATVSASELAVQLPTNNPDAVDMLDRILRLLAAHSVLVCGLKPLPDGGLERRYSLSPVGEFLTRNEDGVSGGTFCLMIQDRVLMEPWYHLKDAILEGGIPFDRAYGMSGFEYLAKDPRLSRIFDQAMYEESTIIMKKILEKYKGFETLKSLVDVGGGIGGTLKMIISKYPSIKGINFDLPHVIRNAPSYPGTFMDNYLNIP
>PAC4GC:21689920
MEIHDGPMTLSQLSVAVGCPADTLHRIMRFLTHNGIFKKELNLSKSQDPESLYYSQTALSRLLTRDKIGFFVLALAGNPGLNAKDLKSGKGSSVKSINASPEDIFWDMIKDDPVYKLFQEFLACHAKTATMAVINYCPKAFEGIRCLVDFGGHEGMAIGMLVKAFPWIRGINFDLPNVIAGASPIDGVEHVAGNMFESVPKADAVMLMWILHDWSDDLCIDILKKCKEAIPADTGKVIIVDAVIDEEGGDEYT
>PAC4GC:21690373
MSSSTKNFAASTMDSSEEESCLFAMQLASASVLPMVLKSAIELDLLELIKKSGAGAFVSPAELAAKLPTSNSEARVMLDRILRLLASYDVLACRLERLPDGGVERRYGLAPVCKFLTKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTIIMKKILETYDGFEGLKTVVDVGGGTGATLNMIVSKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYEALPQKGKVILAECILPEAPDNGLATKNVVHVDVIMLAHNPGGKERTEKEFQALAKGAGFNQLKKVCCAHNSWIMELYK
MDIKPDEEAGLFAMQLTSGSVLQMVLKTAVELDLLELIKKAGPEATASAAELAAQLPTNNPDAVDMLDRILRLLAAHSVLVCSLKPLPDGSLERRYSLSPVGEFLTRNEDGVSVGSFCLLIQDRVATETWYHLKDAILEGGIPFNRAFGMSPFEYFAKDPKLSRIFDQAMYEESTIILKKILEKYKGFEGLKSLVDVGGGIGASLRMIISKYPSIKGINFDLPHVIQNAPSYPGMEHISGDMFLLLCQKPMRFL
>PAC4GC:21707418
MSAFEYSAKDPRFNQLFNQAMQEESTIIMKKVLEKYKGFEGLKTLVDVGGGIGASLKMIISRYPSIKGINFDLPHVIQNVPSYLVERISSDMFDKLVEFLLRLHVNNYHFNKNWICHDWIDLHCEKLLKNCYEALPESGKVITAENLARGPK
>PAC4GC:21670424
MNPPEKPIKISSNEEDEASQYAMQLVNASVMPMVLKACIELDVFGIISRKGPNAQLSPSQIASQIPCHNPDFATHLLDRMLGLLASYSILMCSVNQEERLYSLAPVSKYFLPNANGASLAPLFQADQDKIVMDTWYHIKDAVIQGESPFKRAYGMNISEYMVKDPNYLQLFRASMSSYNSMFMEKLLETYKGFEGLKSIVDVGGGDGSILKTIIGKYPTIKGINFDIPAVIENTATYPGIEQVAGDMFITIPKGDALFLKWILHSWDDEHCIRILKNCYEAIPDHGKVMLVELVVPEVPESRGDVRSKLQFDMIMMNMNPGGKRRTKREFKTLGEAAGFSSIKVECCVYSFSLVELYK
>PAC4GC:21693635
MENAINGSTNSANIEEDEAFNRASAATASFVLPMALDTAIQLRLFEIISKAGEGAGVLPSDIAAQLPNSGPPEAVASRLDCVLRLLASYSLLTCSVSKVANRGIQTRYGLATAGKFFVRDENGASLVVGLRDFTRYQAGFLETCSKLKDAVLGGGNPFERAYGMPIHEYMKSNPDYRRIFQDFMTNYSVMIMKRVCEKYNGFEGLRSIVNVGGGSGVTLDFIISRYPSIHGINFDLPEVIEGAPSYKGVHHISGDMFVQVPQGDAILLKFILHNWSDDQCLQVLKNCYKALPKTGKVIILDTMLPDIPQDDTHSKMVSQFDYIMLMLYGSRERTKAEFEALAKKSGFSEFKVVCNAHSVWVMEVIKTE
>PAC4GC:21710801
MDNERDEEACLFAMQLTTSSVLPMVLKTAIELDLLELIKKAGPEATASASELAAQLPTNNPGAADMIDRILGLLTAHSVLVCVLKPLPHGGVERRYSLAPVGEFLTRNEDGVSVATTCLMIQDRILMEPWYHLKDAILDGGIPFNRTYGISAFEYLAKDPKFNQIFDQAMYEESTIFMKKILQKYKGFEGLKSLVDVGGGIGASIKMIISKYPSIKGINFDLPHVIQNALSSPGVEHISGDMFVSVPKADAIFMKRILHGWSDSQCEKLLKNCYEALPENGKVIIAEAILPEKPNSGLNYLAAAHANVILLTPGGKERSEKQVEALAKKAGFKKLIKVCSAFSIWIVEFHK
>PAC4GC:21710800
MDNKPDEEACLSAMQLTTSSVLPMVLKTAIELDLLELIKKAGPEASASASELVAQLPTNNPDAADMTDRILRLLVANSILVCSLKLLPDGGVQRRYSPAPVGEFFTRNEDGASMGSTCLLIQDRVLMEPWYHLKDAILEGGIPFNRAYGMSAFEYLTKDLRFNRIFNQAMYEQSTMFMKKILEKYKVFEGLKSLVDVGGGIGASLKMIISKFPSIKGINFDLPHVIQNTPSYPGMEHISGDIFVSVPKADGIFMKVKLNFHIFPRTNYFYDLIFT
>PAC4GC:21710809
MDNKPDEEAYLFVMQLTTGSALPMVLKTAIELDLLELIKKAGPEAPASAAELAAQLPTNNPNSADMIDRILRLLAAHSVLVCSLKPLPEDGIERRYSLTPVGEFLTRNEDGVSMATPCLMIQDRVWMEPWYHLKDAILEGGIPFNRAYGMSAFEYLAKDPRFNRIFNQDMYEESTIFMKKILEKYKGFEGLKSLVDVGGGIGGSLDMIISKYPSIKGINFDLPHVIQTAPSYPGQSEGAIGGNYHHFLSYTLSPALELIVAWISFHYPYYFIPSSILQTNTIKLVYLRFESWKVVQEWSTLVWICHNWSDPHCEKLLKNCYEALPENGKVIIAETILPEDPSSGLSALWATYADVIMLAYIPGGKERSEKEFQTLAKKAGFKQLINVCSAFNIWIMEFHK
>PAC4GC:21699410
MDNKPDEEAYLFARQLTTGLALPMVLKAAVELDLLELIKKAGPEASASASELVAQLPTKNPDAADMIDRILRLLAANSVLVCSLKRLPDGGVERHYSLTPVGEFFTRNEDGASVGSTCLLIQDRVLMEPWYHLKDAILEGGIPFNRAYGMSAFEYPAKDLRFNQVFNQAMYEQSTIFMKKILEKYKGFEGLKSLVDVGGGIGASLKMIISKYPSIKGINFDLPHVIQNAPSYPGMEHISGDMFVSVPKAGAIFMKWICHDWSDSHCEKLLKNCYEALPENGKVIIAETIMPEDPNVGLNSLRAAQSDVIMLAYNPGGKERSEREFETLAKKAGFKQLIKACSAFNIWIIEFHK
>PAC4GC:21700251
MDYNKPAEEACLFAMQLTSGSVLQMVLKTAIELDLLELIKKAGPEATVSASELAVQLPTNNPDAVDMLDRILRLLAAHSVLVCGLKPLPDGGLERRYSLSPVGEFLTRNEDGVSGGTFCLMIQDRVLMEPWYHLKDAILEGGIPFDRAYGMSGFEYLAKDPRLSRIFDQAMYEESTIIMKKILEKYKGFETLKSLVDVGGGIGGTLKMIISKYPSIKGINFDLPHVIRNAPSYPDEEAGLFAMQLTSGSVLQMVLKTAVELDLLELIKKAGPEATASAAELAAQLPTNNPDAVDMLDRILRLLAAHSVLVCSLKPLPDGSLERRYSLSPVGEFLTRNEDGVSVGSFCLLIQDRVATETWYHLKDAILEGGIPFNRAFGMSPFEYFAKDPKLSRIFDQAMYEESTIILKKILEKYKGFEGLKSLVDVGGGIGASLKMIISKYPSIKGINFDLPHVIQNAPSYPADAIFMKWICHNWSDSHCEKLLKNCYEALPENGKVIIADIILPEDPNSGPNSLRSSQMDVIMLANNTGGKERSEREFEALAKKAGFKQLIKVCSAFDIWIMELHK
>PAC4GC:21700257
MSAFEYPAKDSRFNRVFNQSMYEQSTIFMKKILEKYKGFEGLKSLVDVGGGIGASLKMIISKYPSIKGINFDLPHVIQNAPSYPGMEHISGDMFVSVPKADAIFMKWICHDWSDSHCEKLLKNCYEALPENGKVIIAETIMPEDPNSGLNSLRAAQGDVIMLAYNPGGKERSEREFETLAKKAGFKQLIKACSAFNIWIIEFHK
>PAC4GC:21700254
MDNKPDEEACLFAMHLTTSSVLPMILKTAIELDLLELIKKTGAKATASAAELAAQLPRNNPDGADIIDRILRLMVAHSVLVCGLKLLPDGGFFARNEDGLSVGTPCLKIQDGAWMEPW
>PAC4GC:21700255
MENKPYEDACLFAMQLTSGSVLPMVLKTVIELDLLELIKKAGPEAKASAAEIAAQLPTNNPGAAGMIDRILQLLTAHSVLVCELKLLPDGGGVERRYSLSPVGEFLTRNEDGVSVGPTCLMNQDRVFMEPWYHLKDAILEGGIPFNRTYGMSAFEYFAKDPRFSRIFNQSMHEESIIIMKKIVEEYKGFEGLKTLVDVGGGIGASLKMIISKYPSIKGINFDLPYVIQNAPSYPGVEHISGDMFDSVPKADAIFMKWICHDWSDSDCEKLLKNCYEALPENGKVIIAETVLPEKPNTRLNSLQAAHSDVMMLAYTPGGKERSKGEFEVLAKKAGFKQLTIVCSALKIWIMEFHK
>PAC4GC:21700256
MDNKPDEEAYLFALQLATGLALPMVLKTAVELDLLELIKKAGPEASASASELVAHLPTNNPDAADMIDRILRLLAANSVLVCSLKLLPDGGVERRYSLTPVGEFFTRNVDGASVGSTCLLIQDRVLMEP
>PAC4GC:21682788
MDYNKPAEEACLFAMQLTSGSVLQMVLKTAIELDLLELIKKAGPEATVSASELAVQLPTNNPDAVDMLDRILRLLAAHSVLVCGLKPLPDGGLERRYSLSPVGEFLTRNEDGVSGGTFCLMIQDRVLMEPWYHLKDAILEGGIPFDRAYGMSGFEYLAKDPRLSRIFDQAMYEESTIIMKKILEKYKGFETLKSLVDVGGGIGGTLKMIISKYPSIKGINFDLPHVIRNAPSYPGTFMDNYLNIP
>PAC4GC:21689920
MEIHDGPMTLSQLSVAVGCPADTLHRIMRFLTHNGIFKKELNLSKSQDPESLYYSQTALSRLLTRDKIGFFVLALAGNPGLNAKDLKSGKGSSVKSINASPEDIFWDMIKDDPVYKLFQEFLACHAKTATMAVINYCPKAFEGIRCLVDFGGHEGMAIGMLVKAFPWIRGINFDLPNVIAGASPIDGVEHVAGNMFESVPKADAVMLMWILHDWSDDLCIDILKKCKEAIPADTGKVIIVDAVIDEEGGDEYT
>PAC4GC:21690373
MSSSTKNFAASTMDSSEEESCLFAMQLASASVLPMVLKSAIELDLLELIKKSGAGAFVSPAELAAKLPTSNSEARVMLDRILRLLASYDVLACRLERLPDGGVERRYGLAPVCKFLTKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFDYHGTDPRFNKVFNNGMSNHSTIIMKKILETYDGFEGLKTVVDVGGGTGATLNMIVSKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYEALPQKGKVILAECILPEAPDNGLATKNVVHVDVIMLAHNPGGKERTEKEFQALAKGAGFNQLKKVCCAHNSWIMELYK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University