Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Handroanthus impetiginosus
Species name
Handroanthus impetiginosus is a species of eudicot in the family Bignoniaceae (trumpet creeper family).
Species info
Gene sequence info
Handroanthus_impetiginosus.4CL.fa
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>PAC4GC:21684733
MTEAGVLTMCLGFAKIPFKFKPGSCGTVIRNARLKIVDPLTGASLPRNQTGEICIKGGAVMKGYFNDPEATKRTIDKGGWLHSGDIGYVDDDDEVFIVDRLKELIKYKGFHVAPAELEALLIAHPSVSDAAVVSMKDEAAGEVPVAFVVRANGSNISEEEIKQYISKQANAISSDHTRTSSTT
>PAC4GC:21676455
MTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDIETGSSLGRNQSGEICIRGDQIMKGYLNDPKSTQTTIDKDGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPYISDAAIVPMKDEQAGEVPVAFVVRSNGSTITEDEIKQFVSKQVVFYKRINRVFFVDAIPKSPAGKILRKDLRARLAAGLSN
>PAC4GC:21680700
MEKSGYGRDGIYRSLRPPLYLPKDPNLSMISFLFRNAASFADKPALIDSHTGKTLTFIQLKSMVSRVSHGLLQLGIKKNDVVLIFSPNSIQFPICFFGIIAIGAIATTVNPIYTVAELSKQVKDSRSKLVITVEDLLPKVKDFGLPVIILGTEKNSVLPIGRLPKITLFSELVNNEGSVNLDSNEFGIKQDDTAVLLYSSGTTGTSKGVILSHRNFIAASLMITADQELAGELHNVFLCVLPMFHVFGLSVIMYAQLQRGNAIVSMSKFDLEMILKTVEKYRITYLWVVPPIILGMAKSSLVKKYNLSSLKQIGSGAAPLGKELMQECAKNFPQATVLQGYGMTETCGIVSLENQNAGPRHSGSTGTLAPGVECQIVSVDKLKPLPPGQLGEIWVRGPNMMQGYYNNPQATKLTIDKQGWVHTGDLGYFDEEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRASNSSLTEEDVKKFVADQVAPFKRLRRVTFINSVPKSASGKILRRELIDKVRSTSKL
>PAC4GC:21671460
MAALDKDGWLHTGDIVYFDKEGYLYVIDRLKEVIKFKGFQVAPADLEAVLISHPEVHDAAIIGERDEEAGEIPVAFVVRKDGSSVSQQALMNYVAKQVAPYKKVRRVYFCASIPRSAAGKILRRELRNLFASRL
>PAC4GC:21690146
MGTEIIFQSKYPPVEVPEDVTLPEFVLSNVEIYLDKVAFVDATTGKGYTYREVKRDIDRFSKALRSLGLRRGRVVVVVLPNVVEYAIIALGIMAAGGVFSGANPNGHASEIKKQVEAAEAKIIVTDGTSYDKVKNLGLPVILIGDDLVEGTINWDELLEAADKANIDAIDEKVQQTDICALPFSSGTTGLSKGVMLTHRNIVANLCSTLFSVGPELIGQISVLGLIPFFHIYGLTGICCATIKNKGKVVVMHRYELRLFLSALITHQITFAPIVPPIILCLVKNPIVDEFDLSKLKLRSIMTAAAPLAPEILNEFEKKFPGVDVQEAYGMTEHSCITLSHGDPNKGHVTAKRNSVGFILPNLEVKFVDPETGNSLPKNTPGEICVRSQCVMKGYYKNEYETTLTIDKDGWLHTGDIGYIDVDGDVFLVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVGLPDKEAGEIPAACVVINSKAKESEEDIMNYVASNVATYKRVRMLQFVDAIPKSPSGKIMRRIIKENMVKDL
>PAC4GC:21696950
MEKSGYGRDGIYRSLRPPLYLPKDPNLSMISFLFRNAASFADKPALIDSHTGKTLTFIQLKSMVSRVSHGLLQLGIKKNDVVLIFSPNSIQFPICFFGIIAIGAIATTVNPIYTVAELSKQVKDSRSKLVITVEDLLPKVKDFGLPVIILGTEKNSVLPIGRLPKITLFSELVNNEGSVNLDSNEFGIKQDDTAVLLYSSGTTGTSKGVILSHRNFIAASLMITADQELAGELHNVFLCVLPMFHVFGLSVIMYAQLQRGNAIVSMSKFDLEMILKTVEKYRITYLWVVPPIILGMAKSSLVKKYNLSSLKQIGSGAAPLGKELMQECAKNFPQATVLQGYGMTETCGIVSLENQNAGPRHSGSTGTLAPGVECQIVSVDKLKPLPPGQLGEIWVRGPNMMQGVLTSKNWIANLLI
>PAC4GC:21687266
MGTEIIFQSKYPPVEVPEDVTLPEFVLSNVEIYLDKVAFVDATTGKGYTYREVKRDIDRFSKALRSLGLRRGRVVVVVLPNVVEYAIIALGIMAAGGVFSGANPNGHASEIKKQVEAAEAKIIVTDGTSYDKVKNLGLPVILIGDDLVEGTINWDELLEAADKANIDAIDEKVQQTDICALPFSSGTTGLSKGVMLTHRNIVANLCSTLFSVGPELIGQISVLGLIPFFHIYGLTGICCATIKNKGKVVVMHRYELRLFLSALITHQITFAPIVPPIILRLVKNPIVDEFDLSKLKLRSIMTAAAPLAPEILNEFEKKFPGVDVQEAYGMTEHSCITLSHGDPNKGHVTAKRNSVGFILPNLEVKFVDPETGNSLPKNTPGEICVRSQCVMKGYYKNEYETTLTIDKDGWLHTGDIGLPDKEAGEIPAACVVINSKAKESEEDIMNYVASNVATYKRVRMLQFVEAIPKSPSGKIMRRIIKENMVRDL
MTEAGVLTMCLGFAKIPFKFKPGSCGTVIRNARLKIVDPLTGASLPRNQTGEICIKGGAVMKGYFNDPEATKRTIDKGGWLHSGDIGYVDDDDEVFIVDRLKELIKYKGFHVAPAELEALLIAHPSVSDAAVVSMKDEAAGEVPVAFVVRANGSNISEEEIKQYISKQANAISSDHTRTSSTT
>PAC4GC:21676455
MTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDIETGSSLGRNQSGEICIRGDQIMKGYLNDPKSTQTTIDKDGWLHTGDIGFIDADDELFIVDRLKEIIKYKGFQVAPAELEALLLNHPYISDAAIVPMKDEQAGEVPVAFVVRSNGSTITEDEIKQFVSKQVVFYKRINRVFFVDAIPKSPAGKILRKDLRARLAAGLSN
>PAC4GC:21680700
MEKSGYGRDGIYRSLRPPLYLPKDPNLSMISFLFRNAASFADKPALIDSHTGKTLTFIQLKSMVSRVSHGLLQLGIKKNDVVLIFSPNSIQFPICFFGIIAIGAIATTVNPIYTVAELSKQVKDSRSKLVITVEDLLPKVKDFGLPVIILGTEKNSVLPIGRLPKITLFSELVNNEGSVNLDSNEFGIKQDDTAVLLYSSGTTGTSKGVILSHRNFIAASLMITADQELAGELHNVFLCVLPMFHVFGLSVIMYAQLQRGNAIVSMSKFDLEMILKTVEKYRITYLWVVPPIILGMAKSSLVKKYNLSSLKQIGSGAAPLGKELMQECAKNFPQATVLQGYGMTETCGIVSLENQNAGPRHSGSTGTLAPGVECQIVSVDKLKPLPPGQLGEIWVRGPNMMQGYYNNPQATKLTIDKQGWVHTGDLGYFDEEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRASNSSLTEEDVKKFVADQVAPFKRLRRVTFINSVPKSASGKILRRELIDKVRSTSKL
>PAC4GC:21671460
MAALDKDGWLHTGDIVYFDKEGYLYVIDRLKEVIKFKGFQVAPADLEAVLISHPEVHDAAIIGERDEEAGEIPVAFVVRKDGSSVSQQALMNYVAKQVAPYKKVRRVYFCASIPRSAAGKILRRELRNLFASRL
>PAC4GC:21690146
MGTEIIFQSKYPPVEVPEDVTLPEFVLSNVEIYLDKVAFVDATTGKGYTYREVKRDIDRFSKALRSLGLRRGRVVVVVLPNVVEYAIIALGIMAAGGVFSGANPNGHASEIKKQVEAAEAKIIVTDGTSYDKVKNLGLPVILIGDDLVEGTINWDELLEAADKANIDAIDEKVQQTDICALPFSSGTTGLSKGVMLTHRNIVANLCSTLFSVGPELIGQISVLGLIPFFHIYGLTGICCATIKNKGKVVVMHRYELRLFLSALITHQITFAPIVPPIILCLVKNPIVDEFDLSKLKLRSIMTAAAPLAPEILNEFEKKFPGVDVQEAYGMTEHSCITLSHGDPNKGHVTAKRNSVGFILPNLEVKFVDPETGNSLPKNTPGEICVRSQCVMKGYYKNEYETTLTIDKDGWLHTGDIGYIDVDGDVFLVDRIKELIKYKGFQVAPAELEAILLTHPSVEDAAVVGLPDKEAGEIPAACVVINSKAKESEEDIMNYVASNVATYKRVRMLQFVDAIPKSPSGKIMRRIIKENMVKDL
>PAC4GC:21696950
MEKSGYGRDGIYRSLRPPLYLPKDPNLSMISFLFRNAASFADKPALIDSHTGKTLTFIQLKSMVSRVSHGLLQLGIKKNDVVLIFSPNSIQFPICFFGIIAIGAIATTVNPIYTVAELSKQVKDSRSKLVITVEDLLPKVKDFGLPVIILGTEKNSVLPIGRLPKITLFSELVNNEGSVNLDSNEFGIKQDDTAVLLYSSGTTGTSKGVILSHRNFIAASLMITADQELAGELHNVFLCVLPMFHVFGLSVIMYAQLQRGNAIVSMSKFDLEMILKTVEKYRITYLWVVPPIILGMAKSSLVKKYNLSSLKQIGSGAAPLGKELMQECAKNFPQATVLQGYGMTETCGIVSLENQNAGPRHSGSTGTLAPGVECQIVSVDKLKPLPPGQLGEIWVRGPNMMQGVLTSKNWIANLLI
>PAC4GC:21687266
MGTEIIFQSKYPPVEVPEDVTLPEFVLSNVEIYLDKVAFVDATTGKGYTYREVKRDIDRFSKALRSLGLRRGRVVVVVLPNVVEYAIIALGIMAAGGVFSGANPNGHASEIKKQVEAAEAKIIVTDGTSYDKVKNLGLPVILIGDDLVEGTINWDELLEAADKANIDAIDEKVQQTDICALPFSSGTTGLSKGVMLTHRNIVANLCSTLFSVGPELIGQISVLGLIPFFHIYGLTGICCATIKNKGKVVVMHRYELRLFLSALITHQITFAPIVPPIILRLVKNPIVDEFDLSKLKLRSIMTAAAPLAPEILNEFEKKFPGVDVQEAYGMTEHSCITLSHGDPNKGHVTAKRNSVGFILPNLEVKFVDPETGNSLPKNTPGEICVRSQCVMKGYYKNEYETTLTIDKDGWLHTGDIGLPDKEAGEIPAACVVINSKAKESEEDIMNYVASNVATYKRVRMLQFVEAIPKSPSGKIMRRIIKENMVRDL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University