Enzyme
The enzyme catalyses the 4'-methylation of naringenin. In vitro it catalyses the 4'-methylation of apigenin, quercetin, daidzein and genistein.
FOMT4
Enzyme
Flavonoid 4'-O-methyltransferase
Enzyme name
EC:2.1.1.231
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + a 4'-hydroxyflavanone = S-adenosyl-L-homocysteine + a 4'-methoxyflavanone [RN:R09792]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];4'-methoxyflavanone [CPD:C19895]
Product
Species information
Hamamelis virginiana
Species name
American witch-hazel (Hamamelis virginiana) is a species of eudicot in the family Hamamelidaceae (witch-hazel family).
Species info
Gene sequence info
Hamamelis_virginiana.FOMT4.fa
Download
>g53784.t1
MDGEPISEADRALFDEPQPAARVDIPPGDDPLSDEARGSDGANELLELVFHSISDEDCVKILKRCREAIPSKDKKGKVIIIDIVIDVMNDEHKLTETKLCFDMLMMALVTGREKSEKEWEKLFLEAGFSRYKITPMFGLRSLIEVYL
>g144941.t1
MRLLEHSGFFVQNHGQEGYLPASRLLLMDVPLSVLPLMISNISKPALPRPWELLSTWFQNTVDPTPFHTVHGKSFYDFLANEPSYGNMFNECMTNDTQLLTNVMIRECKGVFEGLKSLVDVGGGTGTVAKAIADAFPHLKCTVLDK
>g20310.t1
MDPAHCQGATEVFQAQFHIYKHVYNYIDSMALKCAVQLGIPDIIHKHNQPITLPELVSALQVPSTKTSYVQRLMRLLVHSGFFATRKIHENEEEEGYVLTTSSRLLLQDNITSLSTAVLALLDPALVTPWHFLGEWLHGGKLTAFETAHGIDLWDYANQNPEFSKTINGMMASDSQIISSVIQEYRAVFEGLGSLVDVGGGTGTIARAISEAFPHLKCTVLDLPRVVANLPKSENLDYVGGDMFQSIPSSDAVLIKSVLHNWSDEDCVKILKQCREAISSKNEGGKVIIIDMVIDDNKGDYDVAKTKLFNDMLMMVLVAGRERNEKEWEKLFLEAGFSHYKIMPTSGLMSLIEVYP
>g94013.t1
MLSLTCPRQSLDYVGGDMFQPIPSTDAVLIKCVLHMFSDEDCVKVLKRCREAIPSKNEGGKVIIIERMINEKKDEHELTKTKLSNDLMTMIVCDGRERNEKDWEKLFLEAGF
>g105006.t1
MDPAHCQGATEVFQAQFHIYKHVYNYIDSMALKCAVQLGIPDIIHKHNQPITLPELVSALQVPSTKTSYVQRLMRLLVHSGFFATRKIHENEEEEGYVLTTSSRLLLQDNITSLSTAVLALLDPALVTPWHFLGEWLHGGKLTAFETAHGIDLWDYANQNPEFSKTINGMMASDSQIISSVIQEYRAVFEGLGSLVDVGGGTGTIARAISEAFPHLKCTVLDLPHVVANLPKSENLDYVGGDMFQSIPSSDAVLIKSVLHNWSDEDCVKILKQCREAISSKNEGGKVIIIDMVIDDNKGDYDVAKTKLFNDMLMMVLVAGRERNEKEWEKLFLEAGFSHYKIMPTSGLMSLIEVYP
>g9861.t1
MLSLTCPRQSLDYVGGDMFQPIPSTDAVLIKCVLHMFSDEDCVKVLKRCREAIPSKNEGGKVIIIERMINEKKDEHELTKTKLSNDLMTMIVCDGRERNEKDWEKLFLEAGF
MDGEPISEADRALFDEPQPAARVDIPPGDDPLSDEARGSDGANELLELVFHSISDEDCVKILKRCREAIPSKDKKGKVIIIDIVIDVMNDEHKLTETKLCFDMLMMALVTGREKSEKEWEKLFLEAGFSRYKITPMFGLRSLIEVYL
>g144941.t1
MRLLEHSGFFVQNHGQEGYLPASRLLLMDVPLSVLPLMISNISKPALPRPWELLSTWFQNTVDPTPFHTVHGKSFYDFLANEPSYGNMFNECMTNDTQLLTNVMIRECKGVFEGLKSLVDVGGGTGTVAKAIADAFPHLKCTVLDK
>g20310.t1
MDPAHCQGATEVFQAQFHIYKHVYNYIDSMALKCAVQLGIPDIIHKHNQPITLPELVSALQVPSTKTSYVQRLMRLLVHSGFFATRKIHENEEEEGYVLTTSSRLLLQDNITSLSTAVLALLDPALVTPWHFLGEWLHGGKLTAFETAHGIDLWDYANQNPEFSKTINGMMASDSQIISSVIQEYRAVFEGLGSLVDVGGGTGTIARAISEAFPHLKCTVLDLPRVVANLPKSENLDYVGGDMFQSIPSSDAVLIKSVLHNWSDEDCVKILKQCREAISSKNEGGKVIIIDMVIDDNKGDYDVAKTKLFNDMLMMVLVAGRERNEKEWEKLFLEAGFSHYKIMPTSGLMSLIEVYP
>g94013.t1
MLSLTCPRQSLDYVGGDMFQPIPSTDAVLIKCVLHMFSDEDCVKVLKRCREAIPSKNEGGKVIIIERMINEKKDEHELTKTKLSNDLMTMIVCDGRERNEKDWEKLFLEAGF
>g105006.t1
MDPAHCQGATEVFQAQFHIYKHVYNYIDSMALKCAVQLGIPDIIHKHNQPITLPELVSALQVPSTKTSYVQRLMRLLVHSGFFATRKIHENEEEEGYVLTTSSRLLLQDNITSLSTAVLALLDPALVTPWHFLGEWLHGGKLTAFETAHGIDLWDYANQNPEFSKTINGMMASDSQIISSVIQEYRAVFEGLGSLVDVGGGTGTIARAISEAFPHLKCTVLDLPHVVANLPKSENLDYVGGDMFQSIPSSDAVLIKSVLHNWSDEDCVKILKQCREAISSKNEGGKVIIIDMVIDDNKGDYDVAKTKLFNDMLMMVLVAGRERNEKEWEKLFLEAGFSHYKIMPTSGLMSLIEVYP
>g9861.t1
MLSLTCPRQSLDYVGGDMFQPIPSTDAVLIKCVLHMFSDEDCVKVLKRCREAIPSKNEGGKVIIIERMINEKKDEHELTKTKLSNDLMTMIVCDGRERNEKDWEKLFLEAGF
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University