Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Gossypium australe
Species name
Gossypium australe is a species of eudicot in the family Malvaceae (mallow family).
Species info
Gene sequence info
Gossypium_australe.HIDH.fa
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>rna-gnl|WGS:SMMG|mrna.EPI10_004646
MESAASELLIDGAPFFRLYKDGRIKRLSGTENVPPGLDPKTNVESKDVLYSQEIAQSVRIYVPGTVVTSAQKLPLLVYFHGGGFCIESAFSPTYHNYLNALVAEAKIVAVSVNYRRSPEHPLPAAYDDSWTALKWVASHYIGTGPEQWLNHYVDFENVYLSGDSAGANISHHLAVKITNEKLDGMNLVGIILTHPFFWGKEPVGDEVKKPAIRAKMDGIWRLAYPTTSGSDDPWINPIDDQSFGRFLGCKKVLVCVAEKDVMRHRGWYYCEKLKNSEWGGEVEMMEAQGEDHVFHLNKPNCPKAVAMLKKVAEFINQVTKRRRASGGQSKL
>rna-gnl|WGS:SMMG|mrna.EPI10_004644
MASSSNPEIARVFLPSYPMFQLYKDGRVERLRQTVTVPPSDDPKTGVRSKDAPVPPLSSARIFLPKTSDPTAKLPLLIYIHGGAFCIESPFSPTYHNYLTSLVAKANVIAVSVQYRKAPEHNLPAAYDDAWDAINWIASHIERNGPEPWLNENADFDKVFLGGDSAGANIAHNMIMKSAGDDQVRLKFSGLFLMNPFFMNDEPDELISFIFPSSKGPNDPRLNPACIAIKELAAGLVCKRILVCVAEKDFLRERGVSYYETVKNSGWNGVIEMVEIEGEEHVFYLFKPDCEKAGELMDRVSSFLNL
>rna-gnl|WGS:SMMG|mrna.EPI10_011516
MSIVAEAPNYLQVFSDGSVKRFAPEIAPTSEESSGGYKSKDVIIDPSKAITGRIFLPDIPGPCTSSLPVLVYFHGGGFCIGSTTWLGYHHFLGDFAVVSHSIVLSVDYRLAPEHRLPIAYDDCYSSLEWLCSQVSNEPWLTQADISHVFLSGDSAGGNIVHQVAIKAMRNETLRVKVKGLLLIHPFFGSEERTEKERADGATGYVAMNDMFWKLSIPDGSNRDYFGCNFKKQEVSEAEWREFPAVTVYVAGLDFLKERGVMYAEFLQRKEVKRVKLVETENKSHVFHVFHPKSEATCSLQKQMSEFMKNN
>rna-gnl|WGS:SMMG|mrna.EPI10_017713
MGSNVKEIATEVLPYIRVYKDGSVDRLVDSPIVPPCNEDPETGVSSKDIVVSKNPPISARIYLPKHVEQSLKVPLLVYFHGGGFCFESAFSFVETKYMNRLAKQANAVVISIEYRLAPEHPLPIGYEDCWTGLQWVASHSIDGGLKDEPWLSTYVDFDRLYVGGDSSGANLAHNILLRAGSEGLNGVKIKGAFLTHPYFWGSKPIGSEIKNNEEREKLATCMIWHLVYPEAPGGIDNPMLNPVVEGGPSLAGLGCSRLLISTAEKDFVRDRAVSYYHAVKKSGWKGELMELVEVEGEDHAFHILAHESETSMNLIQKLASFIV
>rna-gnl|WGS:SMMG|mrna.EPI10_018468
MSDMAASASIITPPHEVDECRGVLRVYSDGSIWRSSKPSFNVPVNDDGSILWKDIVFDPVHDLQLRLYKPASPSSPKLPVFYYIHGGGFCIGSRAWPNCQNYCFRLASNLQAVVISPDYRLAPENRLPAAIEDGFMAMKWLQAQALANNPDPWLTDVADFSKVFISGDSAGGNIAHNLAVQLGAGSLDLAPVLVRGYVLLAPFFGGTVLTRSEAEGPKDAFLNLELIDRFWRLSVPMGESTDHPLINPFGPVSRRLEQVNLDPILVVVGGSDLLKDRGKEYAERLKNWGKKIEYVEFEGQQHGFFTIDPNSEPAKALMVIIKRFIVENSS
>rna-gnl|WGS:SMMG|mrna.EPI10_029656
MAFCGQVASHANGQGPEPWLNDNADPSRVFLGGESAGANIAHFVAVQAGATKLVGLKIRGMLIVHPYFGTREPSDNELDKYVCPMSTEFDNDPIVNPTADPKLKEMACERVIVLVAEEDEFRNRGEAYYETLAKSGWRGKVEFFETKGEGHCFHVFTDNHNTEVLKNKMVDFINEDI
MESAASELLIDGAPFFRLYKDGRIKRLSGTENVPPGLDPKTNVESKDVLYSQEIAQSVRIYVPGTVVTSAQKLPLLVYFHGGGFCIESAFSPTYHNYLNALVAEAKIVAVSVNYRRSPEHPLPAAYDDSWTALKWVASHYIGTGPEQWLNHYVDFENVYLSGDSAGANISHHLAVKITNEKLDGMNLVGIILTHPFFWGKEPVGDEVKKPAIRAKMDGIWRLAYPTTSGSDDPWINPIDDQSFGRFLGCKKVLVCVAEKDVMRHRGWYYCEKLKNSEWGGEVEMMEAQGEDHVFHLNKPNCPKAVAMLKKVAEFINQVTKRRRASGGQSKL
>rna-gnl|WGS:SMMG|mrna.EPI10_004644
MASSSNPEIARVFLPSYPMFQLYKDGRVERLRQTVTVPPSDDPKTGVRSKDAPVPPLSSARIFLPKTSDPTAKLPLLIYIHGGAFCIESPFSPTYHNYLTSLVAKANVIAVSVQYRKAPEHNLPAAYDDAWDAINWIASHIERNGPEPWLNENADFDKVFLGGDSAGANIAHNMIMKSAGDDQVRLKFSGLFLMNPFFMNDEPDELISFIFPSSKGPNDPRLNPACIAIKELAAGLVCKRILVCVAEKDFLRERGVSYYETVKNSGWNGVIEMVEIEGEEHVFYLFKPDCEKAGELMDRVSSFLNL
>rna-gnl|WGS:SMMG|mrna.EPI10_011516
MSIVAEAPNYLQVFSDGSVKRFAPEIAPTSEESSGGYKSKDVIIDPSKAITGRIFLPDIPGPCTSSLPVLVYFHGGGFCIGSTTWLGYHHFLGDFAVVSHSIVLSVDYRLAPEHRLPIAYDDCYSSLEWLCSQVSNEPWLTQADISHVFLSGDSAGGNIVHQVAIKAMRNETLRVKVKGLLLIHPFFGSEERTEKERADGATGYVAMNDMFWKLSIPDGSNRDYFGCNFKKQEVSEAEWREFPAVTVYVAGLDFLKERGVMYAEFLQRKEVKRVKLVETENKSHVFHVFHPKSEATCSLQKQMSEFMKNN
>rna-gnl|WGS:SMMG|mrna.EPI10_017713
MGSNVKEIATEVLPYIRVYKDGSVDRLVDSPIVPPCNEDPETGVSSKDIVVSKNPPISARIYLPKHVEQSLKVPLLVYFHGGGFCFESAFSFVETKYMNRLAKQANAVVISIEYRLAPEHPLPIGYEDCWTGLQWVASHSIDGGLKDEPWLSTYVDFDRLYVGGDSSGANLAHNILLRAGSEGLNGVKIKGAFLTHPYFWGSKPIGSEIKNNEEREKLATCMIWHLVYPEAPGGIDNPMLNPVVEGGPSLAGLGCSRLLISTAEKDFVRDRAVSYYHAVKKSGWKGELMELVEVEGEDHAFHILAHESETSMNLIQKLASFIV
>rna-gnl|WGS:SMMG|mrna.EPI10_018468
MSDMAASASIITPPHEVDECRGVLRVYSDGSIWRSSKPSFNVPVNDDGSILWKDIVFDPVHDLQLRLYKPASPSSPKLPVFYYIHGGGFCIGSRAWPNCQNYCFRLASNLQAVVISPDYRLAPENRLPAAIEDGFMAMKWLQAQALANNPDPWLTDVADFSKVFISGDSAGGNIAHNLAVQLGAGSLDLAPVLVRGYVLLAPFFGGTVLTRSEAEGPKDAFLNLELIDRFWRLSVPMGESTDHPLINPFGPVSRRLEQVNLDPILVVVGGSDLLKDRGKEYAERLKNWGKKIEYVEFEGQQHGFFTIDPNSEPAKALMVIIKRFIVENSS
>rna-gnl|WGS:SMMG|mrna.EPI10_029656
MAFCGQVASHANGQGPEPWLNDNADPSRVFLGGESAGANIAHFVAVQAGATKLVGLKIRGMLIVHPYFGTREPSDNELDKYVCPMSTEFDNDPIVNPTADPKLKEMACERVIVLVAEEDEFRNRGEAYYETLAKSGWRGKVEFFETKGEGHCFHVFTDNHNTEVLKNKMVDFINEDI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University