Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Gnetum montanum
Species name
Gnetum montanum is a species of seed plant in the family Gnetaceae.
Species info
Gene sequence info
Gnetum_montanum.CHS.fa
Download
>TnS000821187t01
MLWVAKDLVENSKGARVLIVCSGMPLTTFKGSKLDGKHVDNLAGENGLSCPILFYDPLKMSHFYT
>TnS000662845t02
MAEKGVAGAAKRVDAKAFHKEQRSDGVACVLAIGTAVPPNEVDQSTYPDYYFRVTRSEHMTELKQKFQKMCDKSQIKKRYMHLTEEILAEHPSMCEYMGQSLDERQDIVVAEVPRLGKEAAAKAIKEWGQPKSGITHLILCTTSGVDMPGGDYQLARLLGLRPGVKRVMLYQQGCFAGGTVLRLAKDLAENNRGARVLAVCSEITAITFRGPSETHLDNMVGQALFGDGAAAVIVGADPVPQRGERPAFEMLWAAQTILPDSHGAIDGHLKQVGLTFHLLKDVPGIISKNIEKALREAFSQFGVEDWNSLFWIAHPGGPAILDQVEAKLGLLPSKLKATRDVLRDYGNISSACVLFILDRMRKSSAADGALTTGEGLDLGVLFGFGPGLTVETVVLQSMPLCPSSDSDSDSNANGNGHICT
>TnS000002575t05
MVSVVTRLGMEAAEKGGMAKGTILRIAYDLIENNRGTRILIICSELILTTFYNPYLCSSSPHSTIPTPMGGTWKAKKILSELHSAIEGHLQEVGLTIHLMQSVANLVQHRSGSSKRRLVMNRNPEFMYPSIQKEND
>TnS000925063t02
MLNKYPSIGSYDEPSLDARQDLMVPAIPRLGMEAANKAIAEWGQDMNKITHLVFCSTAGVDMPGADYALIRLMGLNPSVKRVMLWHQ
>TnS000925063t03
MAPSAVDATNGHSNASSDIDLSEYRRKQRSDGSACVLAIGTANPPHVVEQKDYADWYFKVTRAEHLTEIKDKFKRICEKSQIGKRHIFLTEEMLNKYPSIGSYDEPSLDARQDLMVPAIPRLGMEAANKAIAEWGQDMNKITHLVFCSTAGVDMPGADYALIRLMGLNPSVKRVMLWHQGCMAGGTVLRVAKDLAENNKGARVLIVCSEITIITFRGPKPDGGHVDNLAGQALFGDGAAAVIVGADPTPEERPWFQLLWTAETLLPDSHGTIEGHLREVGLTFHLMKKVPAVVSGNIEKALREAFDQFNVGEWNSLFWAAHPGGPAILDAVEAELGLDKKRLRATRQVLWDKGNMSSVCVLFILDELRRYSIQNRLSTTGEGHDWGVLFGLGPGLSVETVVLKSFPLPTPEPEPEAAAA
>TnS000715941t01
DKSQIRKRHLTHTGEMLAKHPAMTEYMGQSFDERQSIVIREVPRLGAEAAERALAEWGRPRTEITHMVVCATNGIDMPGTDFALLKMLGLRPGVRRVMMYQQGCFAGGTALRVAKDMAENNGGARVLLVCSEVTAMIFRGPSEPDMSSMVGQAIFADGAAALIVGADPHTALGERAVFEVVHAAQTVLPDSNDAVGGQLTEAGLTFHLRKDLPALVGKHIEACLREAFAEGLGLEEAEMPEWNELFWAVHPGGPAILDGVEAQLGLHGDKLAATRHVLREYGNMSSACVLFILDELRRKSKNALAPRPRLGALLGFGPGLTVEAVLLRS
>TnS001031525t02
DKSQIRKRHLTHTGEMLAKHPAMTEYMGQSFDERQSIVIREVPRLGAEAAEKALAEWGRPRTEITHMVVCATNGIDMPGTDFALLKMLGLRPGVRRVMMYQQGCFAGGTALRVAKDMAENNGGARVLLVCSEVTAMIFRGPSEPDMSSMVGQAIFADGAAALIVGADPHTALGERAVFEVVHAAQTVLPDSNDAVGGQLTEAGLTFHLRKDLPALVGKHIEACLREAFAEGLGLEEAEMPEWNELFWAVHPGGPAILDGVEAQLGLHGDKLAATRHVLREYGNMSSACVLFILDELRGKSKNALAPRPRLGALLGFGPGLTVEAVLLRS
>TnS001031525t01
GAIEGLLSEAGIFFHAARSSGPATGASADADKALANAMKDAASLISGNVEAVLRKGFGKSGMRDWNELFWIVHPA
>TnS000164715t01
DKSQIRKRHLTHTGEMLAKHPAMTEYMGQSFDERQSIVIREVPRLGAEAAEKALAEWGRPRTEITH
>TnS000821171t01
MLAKHPAMTEYMGQSFDERQSIVIREVLRLGTEAAKKALAEWGRPTTEITHMV
>TnS000111469t01
VTSSQIRKRNLTHGEEMLAKHPAMPEYMGQSFDERQSIVIREVRPRRRWPSGNG
>TnS000003591t02
MEDLQQHLAQLDLQSYRSKQRADGNACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSLASYEEASLDARQAIMVPAVPRLGQEAAEKALAEWGRPRSNITHLIFCSTSGVDMPGADYALIKRMRLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLAEEGETPLFELLWTAETILPDSHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFGISDWNKLFWIAHPGGPAILDAVEQTLALEAKKLRATRHVLWENGNMSSACVLFILDEMRKWSAANACSTTGEGLEFGVLFGFGPGLSVETVVLKSCPLPRPVDVEA
>TnS000003591t01
MAPPAAVVDNGNVNVNANGEESVQQQLGKLDLGSYRSNQRADGSACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSMASYEEPSLDARQAIMVPAVPRLGQEAAEKALAEWGRPRSDITHLIFCSTSGVDMPGADYALIKLMRLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLVEEGETPLFELLWTAETILPESHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFSISDWNKLFWIAHPGGPAILDAVEQTLALEAKKLRATRHVLWENGNMSSACVLFILDEMRKWSVANACSTTGEGLEFGVLFGFGPGLSVETVVLKSCPLPRPVDVES
>TnS000667719t01
MASTNHANVNGEESVQQQLELGSYRSNQRADGSACVLAIGTANPPNVVPQSTYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSLASYEEASLDARQAIMVPAVPRLGQEAAEKALAEWGRPRSSITHLIFCSTSGVDMPGADYALIKMMGLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLPDEGETPLFELLWTAETILPDSHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFDISDWNKLFWIAHPGGPAILDAVEQKLALEAKKLRATRHVLWENGNMSSACVLFILDEMRKWSVANACSTTGEGLDFGVLFGFGPGLSVETVVLKSCPLPRPVVVEA
>TnS000100245t01
MAPSTVVDSANVKLDLGSYRSNQRADGSACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSLASYEKPSLYARQAIMVPAVPRLGQEAAEKALAEWGRPRSDITHLIFCSTSGVDMPGADYALIKMMGLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENTRGARVLVVCSELTVTTFRGPRSDGGHLDNLAGQALFGDGASSVVVGADPLAEEGEAPLFELLWTAETILPDSHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFGISDWNKLFWIAHPGGPAILDAVEQTLALEEKKLRATRHVLWENGNMSSACVLFILDEMRRWSAANACSTTGEGLEFGVLFGFGPGLSVETVVLKACPFTRTVEA
>TnS000731165t01
MARPQHYTQSHIHCLHCALCSQLSSNSIYFPSSVANYQALYNMAPSAVADNGNANVTVSADGEEALQQQLAQLELGSYRRNQRADGSACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKHPSLASYEEPSLDARQAIMVPAVPRLGQQAAEKALAEWGRPRSSITHLIFCSTSGVDMPGADYALIKMMGLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLPEEGENPLFELLWTAETILPESHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFAQFGISDWNKLFWIAHPGGPAILDAVEQTLELNAKKLRATRHVLWENGNMSSACVLFILDEMRKWSAANACSTTGEGLDFGVLFGFGPGLSVETVVLKACPLSRTVAA
>TnS000806943t02
MAKSMSNDHGRGNCNETRFKLDVESYQKAQRSDGVTSILAIGAVVPPNKIPQSTYPNYYFWSSFRWHRPRARA
>TnS000806943t01
WGLSFHLLKDVLGIISKNIQSTLHKVFQKFHVHHWNNIFWVAHLRGPTILDQVEDMLQLKPEKLSTTSEELPKHVQCLHALPPGLHAQLLDYFRC
>TnS000299239t02
MPDSEGAIDGHLRQVGLSFHLLKDVPGIISKNIESALHEAFQQFHVHDWNSVFWVAHPGGPAILDQVEDVNNPQRIYL
>TnS000299239t01
MRKSSAASGAETSGEGLELGVLFGFGPGLTVETVVLKSMPLSVTTAAQGL
>TnS000743537t01
MAESMSNGHGQGNCKGTGFKLNVESYRKAQRSDGVAAILAIGTAVPPNEVPQSTYPDYYFRVTASEHMTELKNKFRRMCDNSQINKRYMYLTEEILKEHPAMLDFRASSLDERQDMVVAEVPRLGKEAAAKAIKEWGQPKSSITHLVFCTTSGVDMPGADYQLARMLGLRRNVKRVMLYQQGCYAGGTVLRVAKDLAENNRGARVLVVCSEITAITFRGPSEAHLDSMVGQALFGDGAGALVVGADPEPELGERAVFELLWTAQSIMPDSEGAIDGHLRQVGLSFHLLKDVPGIISKNIESALHEAFQQFHVHDWNSVFWVAHPGGPAILDQVEDVLGLKAEKLSVTCDVLRNYGNMSSACVLFILDRMRKSSAASGAETSGEGLELGVLFGFGPGLTVETVVLKSMPFSATAAIAQ
MLWVAKDLVENSKGARVLIVCSGMPLTTFKGSKLDGKHVDNLAGENGLSCPILFYDPLKMSHFYT
>TnS000662845t02
MAEKGVAGAAKRVDAKAFHKEQRSDGVACVLAIGTAVPPNEVDQSTYPDYYFRVTRSEHMTELKQKFQKMCDKSQIKKRYMHLTEEILAEHPSMCEYMGQSLDERQDIVVAEVPRLGKEAAAKAIKEWGQPKSGITHLILCTTSGVDMPGGDYQLARLLGLRPGVKRVMLYQQGCFAGGTVLRLAKDLAENNRGARVLAVCSEITAITFRGPSETHLDNMVGQALFGDGAAAVIVGADPVPQRGERPAFEMLWAAQTILPDSHGAIDGHLKQVGLTFHLLKDVPGIISKNIEKALREAFSQFGVEDWNSLFWIAHPGGPAILDQVEAKLGLLPSKLKATRDVLRDYGNISSACVLFILDRMRKSSAADGALTTGEGLDLGVLFGFGPGLTVETVVLQSMPLCPSSDSDSDSNANGNGHICT
>TnS000002575t05
MVSVVTRLGMEAAEKGGMAKGTILRIAYDLIENNRGTRILIICSELILTTFYNPYLCSSSPHSTIPTPMGGTWKAKKILSELHSAIEGHLQEVGLTIHLMQSVANLVQHRSGSSKRRLVMNRNPEFMYPSIQKEND
>TnS000925063t02
MLNKYPSIGSYDEPSLDARQDLMVPAIPRLGMEAANKAIAEWGQDMNKITHLVFCSTAGVDMPGADYALIRLMGLNPSVKRVMLWHQ
>TnS000925063t03
MAPSAVDATNGHSNASSDIDLSEYRRKQRSDGSACVLAIGTANPPHVVEQKDYADWYFKVTRAEHLTEIKDKFKRICEKSQIGKRHIFLTEEMLNKYPSIGSYDEPSLDARQDLMVPAIPRLGMEAANKAIAEWGQDMNKITHLVFCSTAGVDMPGADYALIRLMGLNPSVKRVMLWHQGCMAGGTVLRVAKDLAENNKGARVLIVCSEITIITFRGPKPDGGHVDNLAGQALFGDGAAAVIVGADPTPEERPWFQLLWTAETLLPDSHGTIEGHLREVGLTFHLMKKVPAVVSGNIEKALREAFDQFNVGEWNSLFWAAHPGGPAILDAVEAELGLDKKRLRATRQVLWDKGNMSSVCVLFILDELRRYSIQNRLSTTGEGHDWGVLFGLGPGLSVETVVLKSFPLPTPEPEPEAAAA
>TnS000715941t01
DKSQIRKRHLTHTGEMLAKHPAMTEYMGQSFDERQSIVIREVPRLGAEAAERALAEWGRPRTEITHMVVCATNGIDMPGTDFALLKMLGLRPGVRRVMMYQQGCFAGGTALRVAKDMAENNGGARVLLVCSEVTAMIFRGPSEPDMSSMVGQAIFADGAAALIVGADPHTALGERAVFEVVHAAQTVLPDSNDAVGGQLTEAGLTFHLRKDLPALVGKHIEACLREAFAEGLGLEEAEMPEWNELFWAVHPGGPAILDGVEAQLGLHGDKLAATRHVLREYGNMSSACVLFILDELRRKSKNALAPRPRLGALLGFGPGLTVEAVLLRS
>TnS001031525t02
DKSQIRKRHLTHTGEMLAKHPAMTEYMGQSFDERQSIVIREVPRLGAEAAEKALAEWGRPRTEITHMVVCATNGIDMPGTDFALLKMLGLRPGVRRVMMYQQGCFAGGTALRVAKDMAENNGGARVLLVCSEVTAMIFRGPSEPDMSSMVGQAIFADGAAALIVGADPHTALGERAVFEVVHAAQTVLPDSNDAVGGQLTEAGLTFHLRKDLPALVGKHIEACLREAFAEGLGLEEAEMPEWNELFWAVHPGGPAILDGVEAQLGLHGDKLAATRHVLREYGNMSSACVLFILDELRGKSKNALAPRPRLGALLGFGPGLTVEAVLLRS
>TnS001031525t01
GAIEGLLSEAGIFFHAARSSGPATGASADADKALANAMKDAASLISGNVEAVLRKGFGKSGMRDWNELFWIVHPA
>TnS000164715t01
DKSQIRKRHLTHTGEMLAKHPAMTEYMGQSFDERQSIVIREVPRLGAEAAEKALAEWGRPRTEITH
>TnS000821171t01
MLAKHPAMTEYMGQSFDERQSIVIREVLRLGTEAAKKALAEWGRPTTEITHMV
>TnS000111469t01
VTSSQIRKRNLTHGEEMLAKHPAMPEYMGQSFDERQSIVIREVRPRRRWPSGNG
>TnS000003591t02
MEDLQQHLAQLDLQSYRSKQRADGNACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSLASYEEASLDARQAIMVPAVPRLGQEAAEKALAEWGRPRSNITHLIFCSTSGVDMPGADYALIKRMRLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLAEEGETPLFELLWTAETILPDSHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFGISDWNKLFWIAHPGGPAILDAVEQTLALEAKKLRATRHVLWENGNMSSACVLFILDEMRKWSAANACSTTGEGLEFGVLFGFGPGLSVETVVLKSCPLPRPVDVEA
>TnS000003591t01
MAPPAAVVDNGNVNVNANGEESVQQQLGKLDLGSYRSNQRADGSACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSMASYEEPSLDARQAIMVPAVPRLGQEAAEKALAEWGRPRSDITHLIFCSTSGVDMPGADYALIKLMRLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLVEEGETPLFELLWTAETILPESHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFSISDWNKLFWIAHPGGPAILDAVEQTLALEAKKLRATRHVLWENGNMSSACVLFILDEMRKWSVANACSTTGEGLEFGVLFGFGPGLSVETVVLKSCPLPRPVDVES
>TnS000667719t01
MASTNHANVNGEESVQQQLELGSYRSNQRADGSACVLAIGTANPPNVVPQSTYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSLASYEEASLDARQAIMVPAVPRLGQEAAEKALAEWGRPRSSITHLIFCSTSGVDMPGADYALIKMMGLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLPDEGETPLFELLWTAETILPDSHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFDISDWNKLFWIAHPGGPAILDAVEQKLALEAKKLRATRHVLWENGNMSSACVLFILDEMRKWSVANACSTTGEGLDFGVLFGFGPGLSVETVVLKSCPLPRPVVVEA
>TnS000100245t01
MAPSTVVDSANVKLDLGSYRSNQRADGSACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKYPSLASYEKPSLYARQAIMVPAVPRLGQEAAEKALAEWGRPRSDITHLIFCSTSGVDMPGADYALIKMMGLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENTRGARVLVVCSELTVTTFRGPRSDGGHLDNLAGQALFGDGASSVVVGADPLAEEGEAPLFELLWTAETILPDSHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFGQFGISDWNKLFWIAHPGGPAILDAVEQTLALEEKKLRATRHVLWENGNMSSACVLFILDEMRRWSAANACSTTGEGLEFGVLFGFGPGLSVETVVLKACPFTRTVEA
>TnS000731165t01
MARPQHYTQSHIHCLHCALCSQLSSNSIYFPSSVANYQALYNMAPSAVADNGNANVTVSADGEEALQQQLAQLELGSYRRNQRADGSACVLAIGTANPPNVVPQSSYPDFYFRVTKSEHMTELKDKFRRICDKSQIKQRHMLLTEELFDKHPSLASYEEPSLDARQAIMVPAVPRLGQQAAEKALAEWGRPRSSITHLIFCSTSGVDMPGADYALIKMMGLSPHVRRVMLYHQGCMAGGTVLRIAKDLAENNRGARVLVVCSELTVTTFRGPRPDGGHLDNLAGQALFGDGASSVVVGADPLPEEGENPLFELLWTAETILPESHGAIEGHLQEVGLTFHLMRNVASLISSNIGAALQKAFAQFGISDWNKLFWIAHPGGPAILDAVEQTLELNAKKLRATRHVLWENGNMSSACVLFILDEMRKWSAANACSTTGEGLDFGVLFGFGPGLSVETVVLKACPLSRTVAA
>TnS000806943t02
MAKSMSNDHGRGNCNETRFKLDVESYQKAQRSDGVTSILAIGAVVPPNKIPQSTYPNYYFWSSFRWHRPRARA
>TnS000806943t01
WGLSFHLLKDVLGIISKNIQSTLHKVFQKFHVHHWNNIFWVAHLRGPTILDQVEDMLQLKPEKLSTTSEELPKHVQCLHALPPGLHAQLLDYFRC
>TnS000299239t02
MPDSEGAIDGHLRQVGLSFHLLKDVPGIISKNIESALHEAFQQFHVHDWNSVFWVAHPGGPAILDQVEDVNNPQRIYL
>TnS000299239t01
MRKSSAASGAETSGEGLELGVLFGFGPGLTVETVVLKSMPLSVTTAAQGL
>TnS000743537t01
MAESMSNGHGQGNCKGTGFKLNVESYRKAQRSDGVAAILAIGTAVPPNEVPQSTYPDYYFRVTASEHMTELKNKFRRMCDNSQINKRYMYLTEEILKEHPAMLDFRASSLDERQDMVVAEVPRLGKEAAAKAIKEWGQPKSSITHLVFCTTSGVDMPGADYQLARMLGLRRNVKRVMLYQQGCYAGGTVLRVAKDLAENNRGARVLVVCSEITAITFRGPSEAHLDSMVGQALFGDGAGALVVGADPEPELGERAVFELLWTAQSIMPDSEGAIDGHLRQVGLSFHLLKDVPGIISKNIESALHEAFQQFHVHDWNSVFWVAHPGGPAILDQVEDVLGLKAEKLSVTCDVLRNYGNMSSACVLFILDRMRKSSAASGAETSGEGLELGVLFGFGPGLTVETVVLKSMPFSATAAIAQ
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University