Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Gillenia trifoliata
Species name
Bowman's root (Gillenia trifoliata) is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Gillenia_trifoliata.COMT.fa
Download
>Gt00027013
MEGQGSLENYISAWGLSNSICVQMALRAAIELNVLNIIAKSGPGAHLTAQEIVSQIPTSNPNAVESLERILRLLSVHSLLATSLRRPSSQNGETKLQEKAYGLTKVTLCLVPNEDGVSLAPIILIGSEMANVMSFSMLKNTVLDATAAGVSPFKKAHGVTIYEYLSKKPEQGLLFNETMRISSAVLFDDVLKVYRGFEDVEELMDVGGGVGSWLAKTISMHPHIHGINFDLPYIIAQAPQHQGVKHVRGDMFESIPSAKSIMLKWILHNWEDDKCKKLLRNCWEALPETGKVVVVELAFPEELGNTPETANIAVLDIVMMLNYGGRERTIAEFDNLAKAVGFVETKIFPISPVCFVLEFHK
>Gt00030104
MEGNTHVSHVTAGPSSSSSNEARLAILELANMISVPMSLNAVVRLNVPDAIWQGGSNTPLSAFDILARVLPNGGGDAENLQRILRMLTSYGVFAEHLSNPDEGSDDRKFSLTPIGQTLVTDQNGLSYGSYVLQHHQDALMVAWPMVHEAVVDSTVEPFVKVNGEPAYEYYGKKPEMNDLMQKAMSGVSVPFMKAILDGYDGFEGVERLVDVGGSAGDCLRMILQKHPNVREGINFDLPEVVAKAPTIAGMSHVGGDMFKSVPSGDCIFMKWVLSTWTDSECRLIMENCYKALPVGGKLIACEPVLPKKSDDSHRTRALLENDIFVMTIYRAKGKNRTEDELRQLGLSAGFSHFRPFYIDFFYTILEFRK
>Gt00006548
MASPVLEIETQPKLHLDPQTNEQDESYFTAVELTLSSLLPLTMKSAIELDVFNIIAKEGPNAKLSASEIAALIGTKNPDGPDMLDRILRLLASHSILSCLVVDKGDHKSLKRLYSLTPVSKHFVTNEIGVSFGPVMAMMQDKIFTESWSQMKDAIIEGGIPFERAHGSHAFKYAGYDQRFNQAFNTGLNNFTTMLVKKVLELYKGFENLKKVVDVGGGLGVAISLITATYPHIKGINYDLPHVVKDAPKYPGVEHVGGDMFASIPNADALFLKFVRSATIGGVERGAATNRGQSDLPPMEFDSVNIRNRSPDFTWVPHCFLFPHSLHSHSEYGILHDWFDEDCIKLLKNCYKALPVDGKVVVVEAVLPSIPDSSSATKSNSHLDAHMMAQSPGGKERSAEEFMDLATAAGFSGIRLACFATHLGVIEFYK
>Gt00020667
MASPVLELETQPKFHFDPQINEQDESYFTAVELTLSSLLPLTMKSAIELDVFNIIAKEGPNAKLSASEIAARIGTKNPDGPDMLDRILKLLASHSVLSCSVVDKGDHKSLKRLYGLTPVSKHFVTNEIGVSFGPVMAMMQDKIFTESWSQMKDAIIEGGIPFERVHGSHAFKYAGYDQRFNQAFNTGMNNYTTMLVKKVLELYKGFENLKKVVDVGGGLGVAISLITATYPHIKGINYDLPHVVKDAPKYPGVEHVGGDMFASIPNADAVFLKGILHDWFDEDCIKLLKNCYKALPVDGKVVVVEPVLPSIPDSSSATKSNSHLDVHMMAQTPGGKERSAEEFMDLATAAGFSGIRLACFATHIGVIEFYK
>Gt00020726
EDFTFDLPMVLKSALERNVIDIIWATECGAFLSPSDIAAGLPTKNSNSPVLLDQLLRLLASYKILKCSIRTEKDGKVNPSAVLDHEVGIPSYWHTYIMCDLLIPRFHFNDAVLEGGIPFNRAHGMTAFEYP
>Gt00036346
MFTINGEEEAHSQYAMQWASASVFPMVLKAAIELGVLDIIRRAGPGALLSPSQIASQLRSLHNPDAPSILNRMLHLLSAYSVLTCSTKQANGEVVRVYGLAPVSKYFIKNLDGVSLAPLLNLCHDEVILDSWYHLKDAVLEGGLPFSKAYGMNVVEYIERDERFGGGFKDSMKEFNPIFMKEILEIYTGFEGLSTLVDVGGGDGTILNMIISKHPAIKGINYDLPSVVEKSPSHPGIEHIAGDMFVRIPKGDAIFMKWMLHGWDDDRCLMLLKNCYEALPDNGKVIVVDMVIQEAPETSLSAKSLFQFDVYLMNTNVTGKERTERELQSLAKEVGFSDIRVACKSFYLFSRGAVKEYVVSGWICFVIVMHSRDK
>Gt00010695
MASKREPQYVSGEKLDQHKRRWELALEACPNVYSAAAFAPLHRAYILGNLESGEKGLPDAVCLWPRIRQEEYELHPVRMGGPPRASACQSSRDKEAIRSQFFKVDPEGDFSDHTAFGHFIKYYSPKVLSGPCSGACILSSILPKAPDISFSDTTVLAIQLKSSAAMNLPSGAYMYYFRECKTRTSEEWEVSVTRTYPLFTERDLSWGVGRASRHTYGVEVYHPNFLCRQFGFLQSIPKPLHQSLNDATSYRVKKPSDAEMVDARKSLFVVQKAWNKPDVFNVQCTPEFSVWWEDQFLARFPKDPIQANIRLFKSFNLGSSMNDHTRKSFIREMKIKNKKVLIVGVKPFNSNNTSELFEGDDSDDEVQQPSTAAAASTRLTKKGKEKVVYEVRTTHREDKSPAIIIPQKRKERSTAQEEREDDFTTAIAASPPKRISKKRRRNLVIGEEDEAEGEDLSQENPAPQVIRLTLIVLNPIIFPLLSSSLTIFHWMLHGWDDDRCLMLLKNCYKALPDNGKVIVVDMVIQEAPKTSLYAKSLFQFDVYLMNTNVTGKERTERELQGLAKEAGFSDIRVACSAFTFSVVELLKNM
>Gt00022653
MHNTNPMASLEEPKGLPNIPLDDEGRKEEESYCHALQLVVSSVLSFSMQSAIELGVFDIIAKEGPNAKLSSSEIAAHIGTKTPDGPMMLDRILAVLASNSVLDCTVVNGKVDKCFRRLYSLTPVSKHFVTNEDGVSLGPVLTMVQDEVFFKGWLQVKDAVIEGGIPFNRAHGMHHFQYPGVDLRFNKLFNKAMFNHSTIVMKRILDLYKGFEHLTQLVDIGGNLGGAISLITSKYPHIKGINFDLPHVIKHASSYPGVENIGGDMFESIPNGDAIFLKFILHDWLDVDCIKLLKNCYNAIPDDGKVIVVEALLPIKPENSLSVRTNAQLDLHMMTQTPGGMERSQEEFMALATGAGFSGIRYECFTANLWVMEFYK
>Gt00022899
MALQLEEEENFCYAMQLVFSSVLSMSMQSAIELGVFDIIAKAGPGATLSSSEIAAHIGSGTRNSEAPMMLDRILRLLASHSILSCSVVANEDGSDSQRLYSLGPVSNYFVTNEDGVSLGPLMALIQDKVFLDSWSQLKDAVVEGGIPFNRVHGTHAFEYPRLDPRFNQVFNTAMFNHTTIVIKKILHLYKGFEKLTQLVDVGGGLGVTLSLITSKHPHIKGINYDLPHVVKHAPSYPGVEHVGGDMFANVPSGDAIFMKWILHDWSDQHCLNLLKNCYNAIPHDGKVIIVEALLPVMPETSTAVTSTSQIDVLMMTQNPGGKERSREEFMALATGAGFIGISYECFVCNFWVMEFFK
>Gt00037015
MGSTGETQMTPTQVSDEEANLFAMQLASASVLPMVLKAALELDLLEIMVKAGPGAFVSPADLASQLPTKNPDAPVMLDRMLRLLASYSILTYSLRMLPDGKVERLYGLGPVCKFLTKNEDGVSIAPLCLMNQDKVLVESWYHLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMADHSTITMKKLLETYKGFEGLTSVVDVGGGTGAVVNMIVSKYPSIKGINFDLPHVIEDAPQYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYAALPDNGKVILAECILPVAPDSSLATKGVVHIDVVMLAHNPGGKERTEKEFEALAKGSGFRGFRVMCSAFNTYVIEFLKKN
>Gt00012237
MADHSTITMKKLLETYKGFEGLTSVVDVGGGTGAVVNMIVSKYPSIKGINFDLPHVIEDAPQYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYAALPDNGKVILAECILPVAPDSSLATKGVVHIDVVMLAHNPGGKERTEKEFEALAKGSGFRGFRVMCSAFNTYVIEFLKKN
MEGQGSLENYISAWGLSNSICVQMALRAAIELNVLNIIAKSGPGAHLTAQEIVSQIPTSNPNAVESLERILRLLSVHSLLATSLRRPSSQNGETKLQEKAYGLTKVTLCLVPNEDGVSLAPIILIGSEMANVMSFSMLKNTVLDATAAGVSPFKKAHGVTIYEYLSKKPEQGLLFNETMRISSAVLFDDVLKVYRGFEDVEELMDVGGGVGSWLAKTISMHPHIHGINFDLPYIIAQAPQHQGVKHVRGDMFESIPSAKSIMLKWILHNWEDDKCKKLLRNCWEALPETGKVVVVELAFPEELGNTPETANIAVLDIVMMLNYGGRERTIAEFDNLAKAVGFVETKIFPISPVCFVLEFHK
>Gt00030104
MEGNTHVSHVTAGPSSSSSNEARLAILELANMISVPMSLNAVVRLNVPDAIWQGGSNTPLSAFDILARVLPNGGGDAENLQRILRMLTSYGVFAEHLSNPDEGSDDRKFSLTPIGQTLVTDQNGLSYGSYVLQHHQDALMVAWPMVHEAVVDSTVEPFVKVNGEPAYEYYGKKPEMNDLMQKAMSGVSVPFMKAILDGYDGFEGVERLVDVGGSAGDCLRMILQKHPNVREGINFDLPEVVAKAPTIAGMSHVGGDMFKSVPSGDCIFMKWVLSTWTDSECRLIMENCYKALPVGGKLIACEPVLPKKSDDSHRTRALLENDIFVMTIYRAKGKNRTEDELRQLGLSAGFSHFRPFYIDFFYTILEFRK
>Gt00006548
MASPVLEIETQPKLHLDPQTNEQDESYFTAVELTLSSLLPLTMKSAIELDVFNIIAKEGPNAKLSASEIAALIGTKNPDGPDMLDRILRLLASHSILSCLVVDKGDHKSLKRLYSLTPVSKHFVTNEIGVSFGPVMAMMQDKIFTESWSQMKDAIIEGGIPFERAHGSHAFKYAGYDQRFNQAFNTGLNNFTTMLVKKVLELYKGFENLKKVVDVGGGLGVAISLITATYPHIKGINYDLPHVVKDAPKYPGVEHVGGDMFASIPNADALFLKFVRSATIGGVERGAATNRGQSDLPPMEFDSVNIRNRSPDFTWVPHCFLFPHSLHSHSEYGILHDWFDEDCIKLLKNCYKALPVDGKVVVVEAVLPSIPDSSSATKSNSHLDAHMMAQSPGGKERSAEEFMDLATAAGFSGIRLACFATHLGVIEFYK
>Gt00020667
MASPVLELETQPKFHFDPQINEQDESYFTAVELTLSSLLPLTMKSAIELDVFNIIAKEGPNAKLSASEIAARIGTKNPDGPDMLDRILKLLASHSVLSCSVVDKGDHKSLKRLYGLTPVSKHFVTNEIGVSFGPVMAMMQDKIFTESWSQMKDAIIEGGIPFERVHGSHAFKYAGYDQRFNQAFNTGMNNYTTMLVKKVLELYKGFENLKKVVDVGGGLGVAISLITATYPHIKGINYDLPHVVKDAPKYPGVEHVGGDMFASIPNADAVFLKGILHDWFDEDCIKLLKNCYKALPVDGKVVVVEPVLPSIPDSSSATKSNSHLDVHMMAQTPGGKERSAEEFMDLATAAGFSGIRLACFATHIGVIEFYK
>Gt00020726
EDFTFDLPMVLKSALERNVIDIIWATECGAFLSPSDIAAGLPTKNSNSPVLLDQLLRLLASYKILKCSIRTEKDGKVNPSAVLDHEVGIPSYWHTYIMCDLLIPRFHFNDAVLEGGIPFNRAHGMTAFEYP
>Gt00036346
MFTINGEEEAHSQYAMQWASASVFPMVLKAAIELGVLDIIRRAGPGALLSPSQIASQLRSLHNPDAPSILNRMLHLLSAYSVLTCSTKQANGEVVRVYGLAPVSKYFIKNLDGVSLAPLLNLCHDEVILDSWYHLKDAVLEGGLPFSKAYGMNVVEYIERDERFGGGFKDSMKEFNPIFMKEILEIYTGFEGLSTLVDVGGGDGTILNMIISKHPAIKGINYDLPSVVEKSPSHPGIEHIAGDMFVRIPKGDAIFMKWMLHGWDDDRCLMLLKNCYEALPDNGKVIVVDMVIQEAPETSLSAKSLFQFDVYLMNTNVTGKERTERELQSLAKEVGFSDIRVACKSFYLFSRGAVKEYVVSGWICFVIVMHSRDK
>Gt00010695
MASKREPQYVSGEKLDQHKRRWELALEACPNVYSAAAFAPLHRAYILGNLESGEKGLPDAVCLWPRIRQEEYELHPVRMGGPPRASACQSSRDKEAIRSQFFKVDPEGDFSDHTAFGHFIKYYSPKVLSGPCSGACILSSILPKAPDISFSDTTVLAIQLKSSAAMNLPSGAYMYYFRECKTRTSEEWEVSVTRTYPLFTERDLSWGVGRASRHTYGVEVYHPNFLCRQFGFLQSIPKPLHQSLNDATSYRVKKPSDAEMVDARKSLFVVQKAWNKPDVFNVQCTPEFSVWWEDQFLARFPKDPIQANIRLFKSFNLGSSMNDHTRKSFIREMKIKNKKVLIVGVKPFNSNNTSELFEGDDSDDEVQQPSTAAAASTRLTKKGKEKVVYEVRTTHREDKSPAIIIPQKRKERSTAQEEREDDFTTAIAASPPKRISKKRRRNLVIGEEDEAEGEDLSQENPAPQVIRLTLIVLNPIIFPLLSSSLTIFHWMLHGWDDDRCLMLLKNCYKALPDNGKVIVVDMVIQEAPKTSLYAKSLFQFDVYLMNTNVTGKERTERELQGLAKEAGFSDIRVACSAFTFSVVELLKNM
>Gt00022653
MHNTNPMASLEEPKGLPNIPLDDEGRKEEESYCHALQLVVSSVLSFSMQSAIELGVFDIIAKEGPNAKLSSSEIAAHIGTKTPDGPMMLDRILAVLASNSVLDCTVVNGKVDKCFRRLYSLTPVSKHFVTNEDGVSLGPVLTMVQDEVFFKGWLQVKDAVIEGGIPFNRAHGMHHFQYPGVDLRFNKLFNKAMFNHSTIVMKRILDLYKGFEHLTQLVDIGGNLGGAISLITSKYPHIKGINFDLPHVIKHASSYPGVENIGGDMFESIPNGDAIFLKFILHDWLDVDCIKLLKNCYNAIPDDGKVIVVEALLPIKPENSLSVRTNAQLDLHMMTQTPGGMERSQEEFMALATGAGFSGIRYECFTANLWVMEFYK
>Gt00022899
MALQLEEEENFCYAMQLVFSSVLSMSMQSAIELGVFDIIAKAGPGATLSSSEIAAHIGSGTRNSEAPMMLDRILRLLASHSILSCSVVANEDGSDSQRLYSLGPVSNYFVTNEDGVSLGPLMALIQDKVFLDSWSQLKDAVVEGGIPFNRVHGTHAFEYPRLDPRFNQVFNTAMFNHTTIVIKKILHLYKGFEKLTQLVDVGGGLGVTLSLITSKHPHIKGINYDLPHVVKHAPSYPGVEHVGGDMFANVPSGDAIFMKWILHDWSDQHCLNLLKNCYNAIPHDGKVIIVEALLPVMPETSTAVTSTSQIDVLMMTQNPGGKERSREEFMALATGAGFIGISYECFVCNFWVMEFFK
>Gt00037015
MGSTGETQMTPTQVSDEEANLFAMQLASASVLPMVLKAALELDLLEIMVKAGPGAFVSPADLASQLPTKNPDAPVMLDRMLRLLASYSILTYSLRMLPDGKVERLYGLGPVCKFLTKNEDGVSIAPLCLMNQDKVLVESWYHLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMADHSTITMKKLLETYKGFEGLTSVVDVGGGTGAVVNMIVSKYPSIKGINFDLPHVIEDAPQYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYAALPDNGKVILAECILPVAPDSSLATKGVVHIDVVMLAHNPGGKERTEKEFEALAKGSGFRGFRVMCSAFNTYVIEFLKKN
>Gt00012237
MADHSTITMKKLLETYKGFEGLTSVVDVGGGTGAVVNMIVSKYPSIKGINFDLPHVIEDAPQYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYAALPDNGKVILAECILPVAPDSSLATKGVVHIDVVMLAHNPGGKERTEKEFEALAKGSGFRGFRVMCSAFNTYVIEFLKKN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University