Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Gastrodia elata
Species name
Gastrodia elata is a species of monocot in the family Orchidaceae (orchid family).
Species info
Gene sequence info
Gastrodia_elata.HIDH.fa
Download
>GelC02G01446.1
MSSAADDEIIFELSSLIHVYRSGRVERFEPAEFVPASLDLATGVESKDVTVNPSTGLTTRLYLPSSAGRKLPLLLFFHGGGFCVHRAASANYHAYLNHVANRSRVLILSIDYRLAPEHPIPIPYDDCWEALLWASDSSNAEPWISEWGDRSRVFLAGDSSGGNIAHELGMRLGAKGEKVEGLVLLNPYFWGKEKLPAELRQEEERTAMAKACESLWPFLCPRSAAGNDDPRVNPWADGAGSLAGLGCRRVLVTAGDADLISHRARVYCEKLRGSGWEGEVEFLLLEGEDHGFFLSYPGNNKAEAFMDRFAKFCGN
>GelC04G00922.1
MVAIDDSSSSSPDDEVIFQLSNWIKVYRSGRAERFCGTGTIPAGLDPNTGVVSRDVVIDSSNGVSARLYLPTTATGKLPVIVYFHGGAFFLESPFSPIYHPHLNKLSSLAPLLGVSVDYRLAPEHPLPIAYEDSWAALQWVLSWADPWIAKHGDHERVYIAGDSAGGNIAQQMAVRAGEDGVTGIKGMALIHPYFFGKEPVGCEPRDSTFRSDMERSWRFTLPGTSGLDDPIRWRRRPRAWRSWGATKCSWLWQGRISSTAEGRFITII
>GelC06G00731.1
MASPAADAEEIELEIPGFFRLHKTGRFERLVGTDKIPASFDPQTGVDSKDVEIDPITGVSARLYLPPSTGEQRIPLVVYFHGGAFCLESSASPIYHRFLNSLCSLAPLLVVSVDYRLAPEHPLPAAYDDSWTALRWALSRSDPWLADRADLTRVFLAGDSAGANIAHNMALRAAEAGVAIKGSALIHPYFWGSDPVGSESFDLAFRSNIIKIWEFLCPDTTGPDDHRLNPIAAGAPMPAVGRVLVTVAERDVLKHRGKAYFEKIVAGEDWAGEAELVETPDADHVFHLFHPDTEQAKAKIKLLADFFSRV
>GelC11G00957.1
MSSPSDEVDLELFGRIRFYKSGLFERLGVLPILPACERDAATGVGSRDVVIDPSAPVSARLYLPPLPSSSAKIPLIVYFHGGAFCIESAFSFTYHPYLNSLCALAGALIVSVEYRLAPEHPIPVAYDDSWAALRWAVAASDPWIANHADLNRVFLAGDSAGANIAHRMAVRAGAEGGVRVEGLAMIHPYFSTGEKKAGSLGDKLWRLVCPGTVGGTADPWLNPAAEQEGALKGMAGRRAVVFVAEKDMLVDCGKAYYEVLSGSGWEGVAELVQTDEVGHVFHLVRPECDAALEFMNTLAAFFRCDGGDQACWTPKLIHDISQSYY
>GelC11G00707.1
MPEETKKMSSLAASSSPDDVVLELPGIIRFYRSGRADRLFLLELVPPSLNPLTGVQCRDVLINPSTGLSSRLYLPPFPLSSENKKIPILVTFHGGGFCIQRAISSIYHSFIDALTFKSRILAISVDYRLAPESPLPAAYDDCWEALQWVLSNADPWISEFGDLERVFLEGESAGANIAHDLGMRLGRTEGRKLEGIVMAHPMFWGKARIGDEVSGRVPMKAEDVDALWSIVCPGTTGLDDPRLNPVADGAPSLAILGCRRVLVCLAGVDVFRERGMAYYEELRRCGREGEAELFDSVSEEHGFFLFNTDGSKAVEFMDRLVRFFNTHK
>GelC12G00201.1
MAAVAPTAAVTVTIPSAVADEDELEYEIPRYLRYYRSGRVDRLSGTVTVPASLDPATGVDSRDVVVDPVTGVSARLYLPISLPSRLPILLYFHGGGFCIESAASPAYHHHLNSLSALAPLLAVSLNYRLAPEHRLPAAYKDAWAGLLWVLSRADPWVARYGDPSRVFVAGDSAGANIAHHVGMRAGPGVIKGVALVHPFFWGSAPVGSEPADLEFRAGMNRRWWFTFPGAEGLDDPRWNPTGEAAPSLKGLGCERVLVAVAEQDFLKHRGRHYYEKLVGCGWEGAAELVETPAQGHVFHLQDPDSNASVKMNQILANFFACDP
>GelC14G00341.1
MMDEEQKRKHWMESQIDLDVSVEAEIPGFVRKYKSGRIERLLPFDFTEASKDQTTGVSSKDVGIPSGLSARLYLPEGRRRWARLPVLIYFHGGAFVAGSAFSSAYHRLLNSLVSKIGFLGVSVEYRLAPEHPQPAAYNDAWAAVRWVREAGKGEPWLAENADLGSVFLAGDSTGANIAHNMGMRAGKEGEKVEGVVLVQPFFWGKERMGREEVEREGAVVLARQIDEACLRLVFLGKGLDDPWLNPMASGELALLGCRSALVCVAEYDLLRERGRAYYEKLRESGWEGEAEFFETKRKGHGFQLRQPESQKAAQLMHRVVSFLLDKAAARNRSRQLEETWQEVIQEIQGEYVEP
>GelC18G00122.1
MPPPTVSGLVEVENCRNVLRIFSDGSILRDATPSFLIPVDDDGSIEWSDVVFDEARGLRLRLYRPRCRLHAHSANLPIFYYFHGGGFCIGSRTWPNVHNYCLRLSADLGVIVVSPDYRLAPESRLPAALEDSIESVLWLRSEARSPNPNPLLESADFKLLFISGDSAGGTIAHHLAVRFGLDANRLALEPVVIRGYVQLMPFFGGIQRTRSEEDCPSDAFLDLELNDRFWRLSLPAGSTADDPISNPFGPGGPDLSPVRFEPTLVVVGGKDLLRDRAVEYGERLKGFGNPVQVLDFEGQQHGFFTIQPRSEPAGMLMQRIRGFMAENGCKFG
MSSAADDEIIFELSSLIHVYRSGRVERFEPAEFVPASLDLATGVESKDVTVNPSTGLTTRLYLPSSAGRKLPLLLFFHGGGFCVHRAASANYHAYLNHVANRSRVLILSIDYRLAPEHPIPIPYDDCWEALLWASDSSNAEPWISEWGDRSRVFLAGDSSGGNIAHELGMRLGAKGEKVEGLVLLNPYFWGKEKLPAELRQEEERTAMAKACESLWPFLCPRSAAGNDDPRVNPWADGAGSLAGLGCRRVLVTAGDADLISHRARVYCEKLRGSGWEGEVEFLLLEGEDHGFFLSYPGNNKAEAFMDRFAKFCGN
>GelC04G00922.1
MVAIDDSSSSSPDDEVIFQLSNWIKVYRSGRAERFCGTGTIPAGLDPNTGVVSRDVVIDSSNGVSARLYLPTTATGKLPVIVYFHGGAFFLESPFSPIYHPHLNKLSSLAPLLGVSVDYRLAPEHPLPIAYEDSWAALQWVLSWADPWIAKHGDHERVYIAGDSAGGNIAQQMAVRAGEDGVTGIKGMALIHPYFFGKEPVGCEPRDSTFRSDMERSWRFTLPGTSGLDDPIRWRRRPRAWRSWGATKCSWLWQGRISSTAEGRFITII
>GelC06G00731.1
MASPAADAEEIELEIPGFFRLHKTGRFERLVGTDKIPASFDPQTGVDSKDVEIDPITGVSARLYLPPSTGEQRIPLVVYFHGGAFCLESSASPIYHRFLNSLCSLAPLLVVSVDYRLAPEHPLPAAYDDSWTALRWALSRSDPWLADRADLTRVFLAGDSAGANIAHNMALRAAEAGVAIKGSALIHPYFWGSDPVGSESFDLAFRSNIIKIWEFLCPDTTGPDDHRLNPIAAGAPMPAVGRVLVTVAERDVLKHRGKAYFEKIVAGEDWAGEAELVETPDADHVFHLFHPDTEQAKAKIKLLADFFSRV
>GelC11G00957.1
MSSPSDEVDLELFGRIRFYKSGLFERLGVLPILPACERDAATGVGSRDVVIDPSAPVSARLYLPPLPSSSAKIPLIVYFHGGAFCIESAFSFTYHPYLNSLCALAGALIVSVEYRLAPEHPIPVAYDDSWAALRWAVAASDPWIANHADLNRVFLAGDSAGANIAHRMAVRAGAEGGVRVEGLAMIHPYFSTGEKKAGSLGDKLWRLVCPGTVGGTADPWLNPAAEQEGALKGMAGRRAVVFVAEKDMLVDCGKAYYEVLSGSGWEGVAELVQTDEVGHVFHLVRPECDAALEFMNTLAAFFRCDGGDQACWTPKLIHDISQSYY
>GelC11G00707.1
MPEETKKMSSLAASSSPDDVVLELPGIIRFYRSGRADRLFLLELVPPSLNPLTGVQCRDVLINPSTGLSSRLYLPPFPLSSENKKIPILVTFHGGGFCIQRAISSIYHSFIDALTFKSRILAISVDYRLAPESPLPAAYDDCWEALQWVLSNADPWISEFGDLERVFLEGESAGANIAHDLGMRLGRTEGRKLEGIVMAHPMFWGKARIGDEVSGRVPMKAEDVDALWSIVCPGTTGLDDPRLNPVADGAPSLAILGCRRVLVCLAGVDVFRERGMAYYEELRRCGREGEAELFDSVSEEHGFFLFNTDGSKAVEFMDRLVRFFNTHK
>GelC12G00201.1
MAAVAPTAAVTVTIPSAVADEDELEYEIPRYLRYYRSGRVDRLSGTVTVPASLDPATGVDSRDVVVDPVTGVSARLYLPISLPSRLPILLYFHGGGFCIESAASPAYHHHLNSLSALAPLLAVSLNYRLAPEHRLPAAYKDAWAGLLWVLSRADPWVARYGDPSRVFVAGDSAGANIAHHVGMRAGPGVIKGVALVHPFFWGSAPVGSEPADLEFRAGMNRRWWFTFPGAEGLDDPRWNPTGEAAPSLKGLGCERVLVAVAEQDFLKHRGRHYYEKLVGCGWEGAAELVETPAQGHVFHLQDPDSNASVKMNQILANFFACDP
>GelC14G00341.1
MMDEEQKRKHWMESQIDLDVSVEAEIPGFVRKYKSGRIERLLPFDFTEASKDQTTGVSSKDVGIPSGLSARLYLPEGRRRWARLPVLIYFHGGAFVAGSAFSSAYHRLLNSLVSKIGFLGVSVEYRLAPEHPQPAAYNDAWAAVRWVREAGKGEPWLAENADLGSVFLAGDSTGANIAHNMGMRAGKEGEKVEGVVLVQPFFWGKERMGREEVEREGAVVLARQIDEACLRLVFLGKGLDDPWLNPMASGELALLGCRSALVCVAEYDLLRERGRAYYEKLRESGWEGEAEFFETKRKGHGFQLRQPESQKAAQLMHRVVSFLLDKAAARNRSRQLEETWQEVIQEIQGEYVEP
>GelC18G00122.1
MPPPTVSGLVEVENCRNVLRIFSDGSILRDATPSFLIPVDDDGSIEWSDVVFDEARGLRLRLYRPRCRLHAHSANLPIFYYFHGGGFCIGSRTWPNVHNYCLRLSADLGVIVVSPDYRLAPESRLPAALEDSIESVLWLRSEARSPNPNPLLESADFKLLFISGDSAGGTIAHHLAVRFGLDANRLALEPVVIRGYVQLMPFFGGIQRTRSEEDCPSDAFLDLELNDRFWRLSLPAGSTADDPISNPFGPGGPDLSPVRFEPTLVVVGGKDLLRDRAVEYGERLKGFGNPVQVLDFEGQQHGFFTIQPRSEPAGMLMQRIRGFMAENGCKFG
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University