Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Fragaria vesca
Species name
Wild strawberry (Fragaria vesca) is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Fragaria_vesca.4CL.fa
Download
>rna-XM_004291597.2
MEKSGYGRDGVFRSLRPPLVLPRDPNFTMVSFLFNNSSSYPNKPALIDAESSETLSFSQLKSMVIKVAHGLVHLGVKKNDVVLIFAPNSIQFPVCFLGIIAIGAIATTSNPLYTVSELSKQVKDSNPKLVITVPELWEKVKGLNLPAVILGPEGSCSQIESTSKMVGFHDLVKLCGTVSDFPSVNVKQTDTAVLLYSSGTTGLSKGVVLTHRNFIASSVMVTHDQELTGEMHRVFLCVLPIFHVFGLAIITYAQLRKGNAVVSMSRFNLEKILMTVEKYKVTHLWVVPPIILALSKDSVVKKYNLSSLKQIGSGAAPLGKELMEECAKVFPQGLVVQGYGMTETCGIVSVENTLVGPRHSGSAGTLVSGVECQIVSVDTLKPLPPKQLGEIWVRGPNMMIGYFNNPQATQQTIDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGYQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNTSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRRELIEKVRSKI
>rna-XM_004303164.2
MAIDTPQSDIIYRSKLPDIPIPNHLPLHSYIFQNKSHLSSKPCIINGTTGHIYTYADVELTARKVASGLNKLGIKQGDVVMLLLPNTPEFVFTFLGASFRGAMTTAANPFFTPAEIAKQAKASKAKLIITLASYYDKVKDLSSDEVKLMCIDSPPPDSSCLHFSELTQSNEDDVPDVDISPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYSSDDVVLCVLPLFHIYSLNSVLLCGLRAGAAILMMQKFEIVSLLELMQKHRVSVAPIVPPIVLAIAKFPDLDKYDLGSLRVLKSGGAPLGKELEDTVRAKFPNVTLGQGYGMTEAGPVLTMSLAFAKEPFEVKPGGCGTVVRNAELKIVDPETGASLPRNQPGEICIRGHQIMKGYLNDPEATSTTIDKEGWLHTGDIGFIDDDEELFIVDRLKELIKYKGFQVAPAELEALLVTHPHISDAAVVPMKDDAAGEVPVAFVVRSNGTQITEDEIKQFISKQVVFYKRINRVFFIEAIPKSPSGKILRKELRAKLAAGFAN
>rna-XM_004304414.2
MAKSFDSETGTYTSPRPPVHFPENPNLSLTSFLFQSSSSTPHSLALADADSGETLTFLQLKTLVSRLARALIQLHINKDDVVLILSPNSIHFPACFLSVVAIGAIATSCNPVYTVYELSDQIKDCNPKLVITVPELWHKIESFNIPTKYFSDLIRTSDSIADLPAVSVRQSDVAALLYSSGTTGKSKGVILTHRNFITASLMITSDQDRFGEPKHVFLCFVPMFHIMGMSVILYSQLRRGNAVVSMPKFDIDKALKAVEEYRVTQLFVVPPVMIALAKQSVVNKYDLSTVKLIVSGAAPLGKELMEDTAKNIPQAAIVQGYGMTEACGIVSLENPREGSPFSGSTGILAPGIESRIISLDTSTLKALPPNELGEIWVRGPNMMQGYYNNPEATKLTIDKQGWVHTGDLGYFDEEGRLYVVDRLKELIKSYGYQVAPAELEGLLLSHPEILDAVVIPFPDAKAGEVPIAYVVRVPNSLLTEQDILKFVEKLVAPFKRLRSITFVTSVPKSASGKILRRELIQKVRSNM
>rna-XM_004307816.2
MLSIASNTNNTSVVVETADISPTLISASPEKQHPATSTTLHDHHVFKSKLPDLPNISNHLPLHTYCFENVSDFSERPCLIVGSTGKTYSFSETHLISQKTGAGLSKLGITKGDVIMILLQNCAEFVFAFMGASMIGAVTTTANPFYTASEIFKQFKASNAKLIITQSIYVDKLRHSGPDSDQYPKLGEHFQVVTIDDPPENCLHFSVLSGANESELPEVSIDPEDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLVMHKFEIGTLLELIQRYRVCGSCGATAGDSAGEESMVADYDLSSIRVVLSGAAPLGKELEEALRSRVPQAVLGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIEPETGRSLGYNQPGEICIRGSQIMKGYLNDDAATATTVDVEGWLHTGDVGYVDDDGEVFIVDRVKELIKFKGFQVPPAELESLLVSHQSIADAAVVPQKDDAAGEVPVAFVVRSNGNELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAAATPNV
>rna-XM_004309901.2
MENKQDNHEFIFRSKLPDIYIPNHLPLHTYCFENISQFHDRPCLINGNTGQTFTYADVELTSRRVAAGLDKLGIQQGDVVMLLLQNCPEFAFAFLGASYIGAIITTANPFYTPAEVAKQATASKAKLIITQTAYVEKVKDFAKLNNVKVMSVDEASSCDKDVLHFSELTSADESDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKEDVILCVLPLFHIYSLNSVFLCGLRVGATILIMQKFEINKLLELVEKEKVTIAPFVPPIVLNIAKSPDLHQYDLSSIRMVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPYPIKSGACGTVVRNAEMKIIDPDTNESLPRNQSGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDEELFIVDRLKELIKYKGFQVAPAELEAMLISHPNLSDAAVVPMKDEAAGEVPIAFVVRSNGSKISEDDIKQYVSKQVVFYKRISRVFFTDKIPKAPSGKILRKDLRARLAAGVPN
>rna-XM_004310171.2
MGTFVQSSAQDVQEHIFRSQMPAVQVPDNLTLPEFVLKDAELYADNVAFVEAVTGKKITYREVVRDTGRFAKALRSLGLRKGHVVIVVLPNVAEYAIVALGIMAAGGVFSGANPTGHASEIKKQVVAADAKLIVTNGASYEKVKAFGVPVIAIGEETIEGATNWYKLLEAADRAGTNHYQEKVQQTDLCALPFSSGTTGLSKGVMLTHRNLVANLSSTLFGVTREMLGKVTVLGLIPFFHIYGITGICCATLRNKGKVVVMGRYELRTFLNALISEEITFAPIVPPIILNLVKHPVVDEFDLSKLKLQAVMTAAAPLAPDLLKAFESKFPGVQVQEAYGLTEHSCITLTHAGQGFKAKRNSVGFILPNMEVKFIDPETGRSLPRNTPGEICVLSQCTMQGYYNNEEETMRTIDKNGWLHTGDVGYIDDDDNVFIVDRIKELIKFKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAACVVKAAGAKESEEDIINYVASNVAHYKKVRVVHFVDTIPKSPSGKIMRRLVKDTMIEKIKASKLSSN
MEKSGYGRDGVFRSLRPPLVLPRDPNFTMVSFLFNNSSSYPNKPALIDAESSETLSFSQLKSMVIKVAHGLVHLGVKKNDVVLIFAPNSIQFPVCFLGIIAIGAIATTSNPLYTVSELSKQVKDSNPKLVITVPELWEKVKGLNLPAVILGPEGSCSQIESTSKMVGFHDLVKLCGTVSDFPSVNVKQTDTAVLLYSSGTTGLSKGVVLTHRNFIASSVMVTHDQELTGEMHRVFLCVLPIFHVFGLAIITYAQLRKGNAVVSMSRFNLEKILMTVEKYKVTHLWVVPPIILALSKDSVVKKYNLSSLKQIGSGAAPLGKELMEECAKVFPQGLVVQGYGMTETCGIVSVENTLVGPRHSGSAGTLVSGVECQIVSVDTLKPLPPKQLGEIWVRGPNMMIGYFNNPQATQQTIDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGYQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNTSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRRELIEKVRSKI
>rna-XM_004303164.2
MAIDTPQSDIIYRSKLPDIPIPNHLPLHSYIFQNKSHLSSKPCIINGTTGHIYTYADVELTARKVASGLNKLGIKQGDVVMLLLPNTPEFVFTFLGASFRGAMTTAANPFFTPAEIAKQAKASKAKLIITLASYYDKVKDLSSDEVKLMCIDSPPPDSSCLHFSELTQSNEDDVPDVDISPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYSSDDVVLCVLPLFHIYSLNSVLLCGLRAGAAILMMQKFEIVSLLELMQKHRVSVAPIVPPIVLAIAKFPDLDKYDLGSLRVLKSGGAPLGKELEDTVRAKFPNVTLGQGYGMTEAGPVLTMSLAFAKEPFEVKPGGCGTVVRNAELKIVDPETGASLPRNQPGEICIRGHQIMKGYLNDPEATSTTIDKEGWLHTGDIGFIDDDEELFIVDRLKELIKYKGFQVAPAELEALLVTHPHISDAAVVPMKDDAAGEVPVAFVVRSNGTQITEDEIKQFISKQVVFYKRINRVFFIEAIPKSPSGKILRKELRAKLAAGFAN
>rna-XM_004304414.2
MAKSFDSETGTYTSPRPPVHFPENPNLSLTSFLFQSSSSTPHSLALADADSGETLTFLQLKTLVSRLARALIQLHINKDDVVLILSPNSIHFPACFLSVVAIGAIATSCNPVYTVYELSDQIKDCNPKLVITVPELWHKIESFNIPTKYFSDLIRTSDSIADLPAVSVRQSDVAALLYSSGTTGKSKGVILTHRNFITASLMITSDQDRFGEPKHVFLCFVPMFHIMGMSVILYSQLRRGNAVVSMPKFDIDKALKAVEEYRVTQLFVVPPVMIALAKQSVVNKYDLSTVKLIVSGAAPLGKELMEDTAKNIPQAAIVQGYGMTEACGIVSLENPREGSPFSGSTGILAPGIESRIISLDTSTLKALPPNELGEIWVRGPNMMQGYYNNPEATKLTIDKQGWVHTGDLGYFDEEGRLYVVDRLKELIKSYGYQVAPAELEGLLLSHPEILDAVVIPFPDAKAGEVPIAYVVRVPNSLLTEQDILKFVEKLVAPFKRLRSITFVTSVPKSASGKILRRELIQKVRSNM
>rna-XM_004307816.2
MLSIASNTNNTSVVVETADISPTLISASPEKQHPATSTTLHDHHVFKSKLPDLPNISNHLPLHTYCFENVSDFSERPCLIVGSTGKTYSFSETHLISQKTGAGLSKLGITKGDVIMILLQNCAEFVFAFMGASMIGAVTTTANPFYTASEIFKQFKASNAKLIITQSIYVDKLRHSGPDSDQYPKLGEHFQVVTIDDPPENCLHFSVLSGANESELPEVSIDPEDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLVMHKFEIGTLLELIQRYRVCGSCGATAGDSAGEESMVADYDLSSIRVVLSGAAPLGKELEEALRSRVPQAVLGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIEPETGRSLGYNQPGEICIRGSQIMKGYLNDDAATATTVDVEGWLHTGDVGYVDDDGEVFIVDRVKELIKFKGFQVPPAELESLLVSHQSIADAAVVPQKDDAAGEVPVAFVVRSNGNELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAAATPNV
>rna-XM_004309901.2
MENKQDNHEFIFRSKLPDIYIPNHLPLHTYCFENISQFHDRPCLINGNTGQTFTYADVELTSRRVAAGLDKLGIQQGDVVMLLLQNCPEFAFAFLGASYIGAIITTANPFYTPAEVAKQATASKAKLIITQTAYVEKVKDFAKLNNVKVMSVDEASSCDKDVLHFSELTSADESDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKEDVILCVLPLFHIYSLNSVFLCGLRVGATILIMQKFEINKLLELVEKEKVTIAPFVPPIVLNIAKSPDLHQYDLSSIRMVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPYPIKSGACGTVVRNAEMKIIDPDTNESLPRNQSGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDEELFIVDRLKELIKYKGFQVAPAELEAMLISHPNLSDAAVVPMKDEAAGEVPIAFVVRSNGSKISEDDIKQYVSKQVVFYKRISRVFFTDKIPKAPSGKILRKDLRARLAAGVPN
>rna-XM_004310171.2
MGTFVQSSAQDVQEHIFRSQMPAVQVPDNLTLPEFVLKDAELYADNVAFVEAVTGKKITYREVVRDTGRFAKALRSLGLRKGHVVIVVLPNVAEYAIVALGIMAAGGVFSGANPTGHASEIKKQVVAADAKLIVTNGASYEKVKAFGVPVIAIGEETIEGATNWYKLLEAADRAGTNHYQEKVQQTDLCALPFSSGTTGLSKGVMLTHRNLVANLSSTLFGVTREMLGKVTVLGLIPFFHIYGITGICCATLRNKGKVVVMGRYELRTFLNALISEEITFAPIVPPIILNLVKHPVVDEFDLSKLKLQAVMTAAAPLAPDLLKAFESKFPGVQVQEAYGLTEHSCITLTHAGQGFKAKRNSVGFILPNMEVKFIDPETGRSLPRNTPGEICVLSQCTMQGYYNNEEETMRTIDKNGWLHTGDVGYIDDDDNVFIVDRIKELIKFKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAACVVKAAGAKESEEDIINYVASNVAHYKKVRVVHFVDTIPKSPSGKIMRRLVKDTMIEKIKASKLSSN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University