Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Fagopyrum esculentum
Species name
Common buckwheat (Fagopyrum esculentum) is a species of eudicot in the family Polygonaceae (buckwheat family).
Species info
Gene sequence info
Fagopyrum_esculentum.ROMT.fa
Download
>gene:Fes_sc0000112.1.g000023.aua.1
MSQEQANETLNANAHFANHLYSFITSMSLKCAVELEIPDAIHTHGKAMTLSDLSVSISIHPEKAKFLPQLMRILTHSGYFTYTKIPDSEEDNVYGYSLTIASQILLKDHPFSMKPYLLFILDSLLINPWLDLSEWFKTKDAITPFESSNGMTLWESTTHRAELNSVLNDTMASDSKMVASMNEMMVASVLMSNLPLAKALFGGVNTLVDVGGGVGEMARAVAHAFPEMKCMVLDLPHVVDGIEGTHNLRFVAGDMFEVIPPTNAILLKWILHDWSDEYYSVKILKQCRRAIGSKECEEGERKVIIIDIVIDEDEKEENYKKRETQLLYDMEMMALVGGKERTKREWEKLFLDSGFTGGFKIFPLLGFRSVIEVEFGFRFVGSVSHVGSTFDNSNHRRRAPTKARARAGARQACAVHLALETCSSLWRLQRSKVERDGCRRDEGKGREARGLWGMEFPLTMEVRGREWRQEKTEKEDEENGAEKEDETYPDVPNYRLTMEVRGREWRRGWSSSYSRSRQEARENREGRMKVTLDTRVSTKCPSQDTRVQPYWCVSACLCPIPNTSPLSRIGATELEGGCRGAWQAGESEEEGDGTKETINKMIKMLEVGGAELERRRFLWSFQQPTPTKLQMNPNVVLEKSQELRWCRCRGEDVLVWCQVVSRGGLSKGMPKR
>gene:Fes_sc0000112.1.g000004.aua.1
MNPVISKVMSKEKANELLEANIKVSNHIHNFINSMSLKCAVELGIIEAIHSHGKPMSIEDLSSALAINSKKARFLNQLMKFLAQEGYFREHELGYTLTLASELLLANHPYSLRPGLLVVLDPSLVKPWSCLETWFRNEDSTAFSTANGMDLWQYARDEPRFNHEFNESMATDSRVTADISVRSREWAPLFDGLGSLVDVGGGTGEMARTVAEMYPHIQCSVLDLPHVVNGLQGAHNLSYVAGDMFEAIPSADAVLLRHILHDWTDEDSVKILKQCRKAVTRSSNGRRGKVMIIDTVLDNENTNSRARERQHFWSMEMMVLLGGKERNEVEWAKLFEDAGFTGGYKIHPELGLRSLIEVYP
>gene:Fes_sc0000112.1.g000014.aua.1
MDLTADEANEVLIAKGQWLNDVHSFIPSMSLKCAVELGIADAIHNHGKPMTLFDLAASLPIRPQKVEFLPQLMRILVYLGYFSYEKILDDENGQYGYALKLPSHFLLENHPFTVKPYILLILDPHLMKMWLDLNLWFQNDDLSSFQTANGLPIWEYIGDQPELNKVANDTMAGDSKLLASVLLASPQAGEIFEGVKCLVDVAGGLGGMSRAIAHAYPHIKCTVLDLPHVVQGLQGTDNLSYVAGDMFEAIPPTDAILLKWILHDWGDEHSLKILKNCKKAITSNESEGHGKLIIVDIAMEDECEDEDDNDKRETQLLYDMEVMTLYGSKERTKSEWEKLLLGAGFTGGYKIFPLLGFRSVIEVYP
>gene:Fes_sc0000112.1.g000001.aua.1
MNPVTSNGMSKEKAKELLEANIKVCNHIYNFINSMSLKCAVQLGIFEAIHSHGKPMSIEDLSSALAINSQKARYLHQLMKFLAQEGYFREHELGYTLTPASEMLLLNHPYSLRPYLLVVLDPSLVKPWSCLETWFRNEDSTAFSTANGMDLWQYARDEPRFNHEFNESMAIDSRLSADISVRNREWAPLFDGLGSLVDVGGGTGEMARAVAEMYPHIKCSVLDLPHVVNGLQGDHNLTYVAGDMFEAIPSADAVLLKHILHDWTDEDSVKILKQCRKAVMSSGSGRRGKVMIIDRVLGIENTDSKAREIQHFWSMEMMVMLGGKERNEVEWGKLFEDAGFTCGYKIHPELGLRSLIEHLAANPVFYERTKHLRIDCHFVRDEAQKGFLTTAHVPSFLQLADIFTKVLGEQQHLFYLASLACVVLSIGAQAHYCTSQLALTFSRLSSSCSREIPTGHLITSPTATGGGDWRLRAAGDSRPDTPYCFGGPSKSISVRL
>gene:Fes_sc0000112.1.g000017.aua.1
MSLKCAVELGIADAIHNHGKPMTLLDLAASLPIHPQKAEFLPQLMRILVHLGYFSYEKILDDENGGYGYALKLPSQLLLEDHPFCVKPYILLVLNPFLVNPWLDLSVWFQNDEPTSFYTSNRMPFWDYTSFEPALNKIMKDTMASDSKLLASVLMASHRAHEIFEGVNSLVDVGGGLGEMARAIVDAYPHIKCIVLDLPHVIEGLEGSVNLSYVAGDMFEAIPPTDAILLKWIMHDWSDECSVKILKHCKKAITSNEFEGQGKVIIIDIVIDEDCQNEEEYNKRQTQLLYDMEMMALFTGKERTKGEFEKLFLDAGFTGGFKIFPLLGFRSVIEVYP
>gene:Fes_sc0000112.1.g000012.aua.1
MGSAEHTITGDEANELLKANAHFARHLYGFIIPMSLKCAVQLGIPDAINRHGKPMTLAELCKALPIHPQKTQFLPQLMRILAHAGHFSKHRLPGSEETAYGLTPVSQFLLDDHPFTGKPHLLFAIGHKFMDSWLGLSRWFQSGTDQTPFHTAHGMSLWDCTKQDHELNRNINDAMAGDSRMVASVLVAKDEELGRALFGGVRSLVDVGGGVGGLIQPIAAAYPEMKCTVLDLPQVVEASKETENLKFVAGDMFVHVPPADAVLLKWLLHDWDDEDSVRILKQCRKAVTSNGGRGKVIIIEVVLNNEDDGDDKLRRTQLLYDMQMMGILAGKERSEKEWKKIFDDAGFAGGYKIYPVLGFRSVIEVYP
>gene:Fes_sc0000112.1.g000025.aua.1
MDPTQLSKDQANEVLNAKTHFTNHLYSFIISMSLRCAVELGIADAIHSHGKPITLSDLADSIPIHPQKAAFLPQIMRILTHSGFFAYSTDENVYSLTLVSQLLLKDHPFSVKPYILLILDPLLMNPWIDLSDWFKNDVGTPFHSCNGIEFWECTSHKPEFGEIMNDTMAGDSRMVAKALLANPLSQDLFAGIESLVDVGGGIGEMAKAISIAFPLVKCMVLDLPHVVEGLEGTHNLSFIAGDMFVDIPSTNAILLKWILHDWSDECSVKILKQCKKAITSNESNEGKGKVIIIEIVMEEDEDEEDYKTKETQLFFDMEMMTVVAGKERSRKQWEKLFLDAGYMGGFKVYPLSGFRSIIELYP
>gene:Fes_sc0003074.1.g000011.aua.1
MNSSRMSQEQANETLNANAHFANHLYSFITSMSLKCAVELEIADAIHSHGKPMTLSDLAVSIPIHPEKAKFLPQIMRILTHSGYFTYTKIPDSENDNAYGYSLTIASQILLRDHPFSMKPYLQFILDSLLINPWLDLSEWFKTKDAITPFESSNGMTLWECTSHRAELNNVFNSTMASDSKMVASVLMSNRPLAKDLFGGVNRLVDVGGGVGEMARAVANDFPEMKCMVLDLPHVVDGVQGTHNLSFVAGDMFEVIPPTNAILLKWILHDWSDEYSVKILKQCKKAITGKECEGERKVIIIDIVIDEDEKDYKKRETQLFYDMEMMALVRGKERTKREWEKLFLDAGFTGGFKIFPLLGFRSVIEVYP
>gene:Fes_sc0007262.1.g000002.aua.1
MDSADHISGGGEVSELLNANAHFARHLYGFIMPMSLKCAVQLGIPDAINRHGKPMTLAELCKALTIHPQKTRFLPQLMRILSHAGHFSKHRLPGSEEETAYGLTPVSQFLLQDHPFTVKPHLLFAIGHKLMDSWLGLSRWFQSGTDQTPFHTVHGMSFWECMKHDHELNRNFNDAMVGDSRMVASVLVANDELSRALFGGVRSLVDVGGGIGGLVRPIAAAYPEMKCTVLDLPQVVEASEETENLKFVAGDMFLHVPSADAVLIKWVLHDWDDEDSVRILKQCRNAVTGNGGRGKVIIIEVVINNEDDGDDKLQRTQLLFDMQMMGIVAGKERSEKEWKKIFDDAGFAGGYKIYPVLGIRSVIENKLDSREFDHRIECLEEEDALLLTKALGNQSVFVTFDWFIQVSFDTENRLTSDKIRDDGFPVMRRARSVGMSGWHINREGNGEGEAAKSRRVGRVICGDSGDYGQTSFGGETAKGKFSSFKKTCLEIVNS
MSQEQANETLNANAHFANHLYSFITSMSLKCAVELEIPDAIHTHGKAMTLSDLSVSISIHPEKAKFLPQLMRILTHSGYFTYTKIPDSEEDNVYGYSLTIASQILLKDHPFSMKPYLLFILDSLLINPWLDLSEWFKTKDAITPFESSNGMTLWESTTHRAELNSVLNDTMASDSKMVASMNEMMVASVLMSNLPLAKALFGGVNTLVDVGGGVGEMARAVAHAFPEMKCMVLDLPHVVDGIEGTHNLRFVAGDMFEVIPPTNAILLKWILHDWSDEYYSVKILKQCRRAIGSKECEEGERKVIIIDIVIDEDEKEENYKKRETQLLYDMEMMALVGGKERTKREWEKLFLDSGFTGGFKIFPLLGFRSVIEVEFGFRFVGSVSHVGSTFDNSNHRRRAPTKARARAGARQACAVHLALETCSSLWRLQRSKVERDGCRRDEGKGREARGLWGMEFPLTMEVRGREWRQEKTEKEDEENGAEKEDETYPDVPNYRLTMEVRGREWRRGWSSSYSRSRQEARENREGRMKVTLDTRVSTKCPSQDTRVQPYWCVSACLCPIPNTSPLSRIGATELEGGCRGAWQAGESEEEGDGTKETINKMIKMLEVGGAELERRRFLWSFQQPTPTKLQMNPNVVLEKSQELRWCRCRGEDVLVWCQVVSRGGLSKGMPKR
>gene:Fes_sc0000112.1.g000004.aua.1
MNPVISKVMSKEKANELLEANIKVSNHIHNFINSMSLKCAVELGIIEAIHSHGKPMSIEDLSSALAINSKKARFLNQLMKFLAQEGYFREHELGYTLTLASELLLANHPYSLRPGLLVVLDPSLVKPWSCLETWFRNEDSTAFSTANGMDLWQYARDEPRFNHEFNESMATDSRVTADISVRSREWAPLFDGLGSLVDVGGGTGEMARTVAEMYPHIQCSVLDLPHVVNGLQGAHNLSYVAGDMFEAIPSADAVLLRHILHDWTDEDSVKILKQCRKAVTRSSNGRRGKVMIIDTVLDNENTNSRARERQHFWSMEMMVLLGGKERNEVEWAKLFEDAGFTGGYKIHPELGLRSLIEVYP
>gene:Fes_sc0000112.1.g000014.aua.1
MDLTADEANEVLIAKGQWLNDVHSFIPSMSLKCAVELGIADAIHNHGKPMTLFDLAASLPIRPQKVEFLPQLMRILVYLGYFSYEKILDDENGQYGYALKLPSHFLLENHPFTVKPYILLILDPHLMKMWLDLNLWFQNDDLSSFQTANGLPIWEYIGDQPELNKVANDTMAGDSKLLASVLLASPQAGEIFEGVKCLVDVAGGLGGMSRAIAHAYPHIKCTVLDLPHVVQGLQGTDNLSYVAGDMFEAIPPTDAILLKWILHDWGDEHSLKILKNCKKAITSNESEGHGKLIIVDIAMEDECEDEDDNDKRETQLLYDMEVMTLYGSKERTKSEWEKLLLGAGFTGGYKIFPLLGFRSVIEVYP
>gene:Fes_sc0000112.1.g000001.aua.1
MNPVTSNGMSKEKAKELLEANIKVCNHIYNFINSMSLKCAVQLGIFEAIHSHGKPMSIEDLSSALAINSQKARYLHQLMKFLAQEGYFREHELGYTLTPASEMLLLNHPYSLRPYLLVVLDPSLVKPWSCLETWFRNEDSTAFSTANGMDLWQYARDEPRFNHEFNESMAIDSRLSADISVRNREWAPLFDGLGSLVDVGGGTGEMARAVAEMYPHIKCSVLDLPHVVNGLQGDHNLTYVAGDMFEAIPSADAVLLKHILHDWTDEDSVKILKQCRKAVMSSGSGRRGKVMIIDRVLGIENTDSKAREIQHFWSMEMMVMLGGKERNEVEWGKLFEDAGFTCGYKIHPELGLRSLIEHLAANPVFYERTKHLRIDCHFVRDEAQKGFLTTAHVPSFLQLADIFTKVLGEQQHLFYLASLACVVLSIGAQAHYCTSQLALTFSRLSSSCSREIPTGHLITSPTATGGGDWRLRAAGDSRPDTPYCFGGPSKSISVRL
>gene:Fes_sc0000112.1.g000017.aua.1
MSLKCAVELGIADAIHNHGKPMTLLDLAASLPIHPQKAEFLPQLMRILVHLGYFSYEKILDDENGGYGYALKLPSQLLLEDHPFCVKPYILLVLNPFLVNPWLDLSVWFQNDEPTSFYTSNRMPFWDYTSFEPALNKIMKDTMASDSKLLASVLMASHRAHEIFEGVNSLVDVGGGLGEMARAIVDAYPHIKCIVLDLPHVIEGLEGSVNLSYVAGDMFEAIPPTDAILLKWIMHDWSDECSVKILKHCKKAITSNEFEGQGKVIIIDIVIDEDCQNEEEYNKRQTQLLYDMEMMALFTGKERTKGEFEKLFLDAGFTGGFKIFPLLGFRSVIEVYP
>gene:Fes_sc0000112.1.g000012.aua.1
MGSAEHTITGDEANELLKANAHFARHLYGFIIPMSLKCAVQLGIPDAINRHGKPMTLAELCKALPIHPQKTQFLPQLMRILAHAGHFSKHRLPGSEETAYGLTPVSQFLLDDHPFTGKPHLLFAIGHKFMDSWLGLSRWFQSGTDQTPFHTAHGMSLWDCTKQDHELNRNINDAMAGDSRMVASVLVAKDEELGRALFGGVRSLVDVGGGVGGLIQPIAAAYPEMKCTVLDLPQVVEASKETENLKFVAGDMFVHVPPADAVLLKWLLHDWDDEDSVRILKQCRKAVTSNGGRGKVIIIEVVLNNEDDGDDKLRRTQLLYDMQMMGILAGKERSEKEWKKIFDDAGFAGGYKIYPVLGFRSVIEVYP
>gene:Fes_sc0000112.1.g000025.aua.1
MDPTQLSKDQANEVLNAKTHFTNHLYSFIISMSLRCAVELGIADAIHSHGKPITLSDLADSIPIHPQKAAFLPQIMRILTHSGFFAYSTDENVYSLTLVSQLLLKDHPFSVKPYILLILDPLLMNPWIDLSDWFKNDVGTPFHSCNGIEFWECTSHKPEFGEIMNDTMAGDSRMVAKALLANPLSQDLFAGIESLVDVGGGIGEMAKAISIAFPLVKCMVLDLPHVVEGLEGTHNLSFIAGDMFVDIPSTNAILLKWILHDWSDECSVKILKQCKKAITSNESNEGKGKVIIIEIVMEEDEDEEDYKTKETQLFFDMEMMTVVAGKERSRKQWEKLFLDAGYMGGFKVYPLSGFRSIIELYP
>gene:Fes_sc0003074.1.g000011.aua.1
MNSSRMSQEQANETLNANAHFANHLYSFITSMSLKCAVELEIADAIHSHGKPMTLSDLAVSIPIHPEKAKFLPQIMRILTHSGYFTYTKIPDSENDNAYGYSLTIASQILLRDHPFSMKPYLQFILDSLLINPWLDLSEWFKTKDAITPFESSNGMTLWECTSHRAELNNVFNSTMASDSKMVASVLMSNRPLAKDLFGGVNRLVDVGGGVGEMARAVANDFPEMKCMVLDLPHVVDGVQGTHNLSFVAGDMFEVIPPTNAILLKWILHDWSDEYSVKILKQCKKAITGKECEGERKVIIIDIVIDEDEKDYKKRETQLFYDMEMMALVRGKERTKREWEKLFLDAGFTGGFKIFPLLGFRSVIEVYP
>gene:Fes_sc0007262.1.g000002.aua.1
MDSADHISGGGEVSELLNANAHFARHLYGFIMPMSLKCAVQLGIPDAINRHGKPMTLAELCKALTIHPQKTRFLPQLMRILSHAGHFSKHRLPGSEEETAYGLTPVSQFLLQDHPFTVKPHLLFAIGHKLMDSWLGLSRWFQSGTDQTPFHTVHGMSFWECMKHDHELNRNFNDAMVGDSRMVASVLVANDELSRALFGGVRSLVDVGGGIGGLVRPIAAAYPEMKCTVLDLPQVVEASEETENLKFVAGDMFLHVPSADAVLIKWVLHDWDDEDSVRILKQCRNAVTGNGGRGKVIIIEVVINNEDDGDDKLQRTQLLFDMQMMGIVAGKERSEKEWKKIFDDAGFAGGYKIYPVLGIRSVIENKLDSREFDHRIECLEEEDALLLTKALGNQSVFVTFDWFIQVSFDTENRLTSDKIRDDGFPVMRRARSVGMSGWHINREGNGEGEAAKSRRVGRVICGDSGDYGQTSFGGETAKGKFSSFKKTCLEIVNS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University