Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Fagopyrum esculentum
Species name
Common buckwheat (Fagopyrum esculentum) is a species of eudicot in the family Polygonaceae (buckwheat family).
Species info
Gene sequence info
Fagopyrum_esculentum.4CL.fa
Download
>gene:Fes_sc0000639.1.g000012.aua.1
MTTVSVDAQPQLPELRTVSVDAQPQLPELSVAPAVIPVASTDPTHEHIFKSKLPPISIPNHLPLHTYCFENLAEIGDRPCLIVGSTGKIYSFSETYVICRKTAAGLLKLGIGKGDAIMLLLHNNAEFAFSFFAASMIGAVVTTANPYYTSSEIAKQLSASKTKLIVTHGQYVDKLRDHHPAGLKVGDQGFTVVTVDDPPENCLHFSILSDADDKDLKLKETVEEGFESNEAVALPFSSGTTGLPKGVVLTHKSLITSIAQQVDGENPNLYMTPEDVVLCLLPLFHIYSLNSVLLCAMRAGSAVLLVQKFEIATLLELLQRHRVTVAAVVPPLVLALAKNPMVEKFDLGAIRAVLSGAAPLGKELEDALRSRLPQAVLGQGYGMTEAGPVLAMCLAFAKEPFPTKAGSCGTVVRNADLKVIDPETGLSLGFNQPGEICIRGDQIMKGYLNDDAATAATIDAQGWLHTGDIGYVDDDNEVFIVDRVKEIIKFKGFQVAPAELEALLVSHPSIADAAVVPQKDDVNGEVPVAFVVRSEGFDLTEDSVKEFIAKQVVFYKKLHKVYFVHAIPKSPSGKILRKDLRAKLAAAAIESPAP
>gene:Fes_sc0001279.1.g000009.aua.1
MGTQATHQEHIFGSKYGPVSVPSDITLPDFVLQDAELYSDKVAFVEAVTGKEYTYGQVAKDTRRFAKALLSLGIRKGNVIVVVLPNVAEYAIVALGIMAAGAVFSGVNPASHASEIKKQADAADAKLVVTNGSIYEKVKDLKLPVIVIGEEQVPTAMNWNSVLEASEKANINSIIAPINQTDLCALPFSSGTTGVSKGVMLTHRNLVANLSSTLYGVGPDMVGKVTTLGLMPFFHIYGITGICCATLRNKGKVVVMSRFDLRTFMNALITHEVTFAPVVPPILLQLVKSPVVDEFDLTRLKLQAVMTAAAPLAPELLNAFETKFPGVQVQEAYGLTEHSCITLTHSSQGQTPAKRNSVGFILPNIELKFIDPDSGRSLPSNTPGELCVRSQCVMQGYYKNEEETGHTIDKEGWLHTGDVGYIDEDGSVFVVDRIKELIKYKGFQVAPAELEAVLLAHPSVEDAAVIPLPDEDAGEIPAACVVLSQRGKDTTEEDIMEFVGSNVATYKRVRQVHFMEMIPKSASGKIMRRLLKDKILMKKKKITNLLL
>gene:Fes_sc0010201.1.g000004.aua.1
MAADLTNHHNQTQKTPNPNKNYPPWYSPQTGVYNSKFSPIKLPTDPNLDVVSFIFSQKHFGKSALVDSSSGSFISYNELFPLVNSLAFGLYELGVSKGDVVLILLPNSIFYPVILLGVLYLGAIVAPLNPLSSFSEVKKQTLDSHAKWAFTTNSLLEKIKELDVRAIEVPHDVGSISEITKSSIFHTLISSDLKNSSSFRDGIVISQDDTAAIMCSSGTTGASKCVVISHRNLISMVELFVRFEASQYHDEISWCNVYLAVVPMYHIYGLALYAMGLISLGTCIVVMKKFDIDDMVKAIDKYGVTHFPVVPPLLRALTLKAKSLNDGNCALRSLRQVSCGAAATSPLLIDDFVRTFPHVDFIQVPLTFDHLHLNKLSFHFSVVKLNSCCHGYGMTESTAVGARGFNTATVRNYTSAGLLAPNTQAKVVDCITGSCVPPGKAGELWLRGPGTMQGYLNNKEATSTAIEEDGWLHTGDLVYIDHDGYLYILDRLKDMIKYKGFQIAPADLEAILMTHPEILDASVIGVADERVGEVPVAYVVRKPDSKLSSNEVMKYVEMQVAPYKKVRKVVFVHSIPKSPAGKVLRRHLRTMLPSNI
>gene:Fes_sc0029600.1.g000002.aua.1
MPCDLCKYDRAGADGEELLVDSVAVDTGHTIDKEGWIHTGDVVYIDEDGSAFVVNRIKEIINCKGFIILLAHPSVEDAAVILLLDEDAGAIPAACVGLSQRGKATTETANSG
>gene:Fes_sc0060999.1.g000001.aua.1
MPKFDIKAMCELVQKYKVTIAPFVPPIVLAITKSPDVESYDLSSIRLIMSGAAPVGKDLEDAFRAKLPNAVLGQGYGMTEAGPVLAMCLAFAKEPMEVKSGACGTVVRNAELKIVDPETGASLPRNEPGEICIRGSQIMKGYLNDPEATKNTIDEEGWLHTGDIGLVDDNDEIFIVDRLKELIKYKGFQVAPAELEGLLINHPNISDAAVVGMKDEAAGEVPVAFIVKSNGTLITEDDIKKYISDQ
MTTVSVDAQPQLPELRTVSVDAQPQLPELSVAPAVIPVASTDPTHEHIFKSKLPPISIPNHLPLHTYCFENLAEIGDRPCLIVGSTGKIYSFSETYVICRKTAAGLLKLGIGKGDAIMLLLHNNAEFAFSFFAASMIGAVVTTANPYYTSSEIAKQLSASKTKLIVTHGQYVDKLRDHHPAGLKVGDQGFTVVTVDDPPENCLHFSILSDADDKDLKLKETVEEGFESNEAVALPFSSGTTGLPKGVVLTHKSLITSIAQQVDGENPNLYMTPEDVVLCLLPLFHIYSLNSVLLCAMRAGSAVLLVQKFEIATLLELLQRHRVTVAAVVPPLVLALAKNPMVEKFDLGAIRAVLSGAAPLGKELEDALRSRLPQAVLGQGYGMTEAGPVLAMCLAFAKEPFPTKAGSCGTVVRNADLKVIDPETGLSLGFNQPGEICIRGDQIMKGYLNDDAATAATIDAQGWLHTGDIGYVDDDNEVFIVDRVKEIIKFKGFQVAPAELEALLVSHPSIADAAVVPQKDDVNGEVPVAFVVRSEGFDLTEDSVKEFIAKQVVFYKKLHKVYFVHAIPKSPSGKILRKDLRAKLAAAAIESPAP
>gene:Fes_sc0001279.1.g000009.aua.1
MGTQATHQEHIFGSKYGPVSVPSDITLPDFVLQDAELYSDKVAFVEAVTGKEYTYGQVAKDTRRFAKALLSLGIRKGNVIVVVLPNVAEYAIVALGIMAAGAVFSGVNPASHASEIKKQADAADAKLVVTNGSIYEKVKDLKLPVIVIGEEQVPTAMNWNSVLEASEKANINSIIAPINQTDLCALPFSSGTTGVSKGVMLTHRNLVANLSSTLYGVGPDMVGKVTTLGLMPFFHIYGITGICCATLRNKGKVVVMSRFDLRTFMNALITHEVTFAPVVPPILLQLVKSPVVDEFDLTRLKLQAVMTAAAPLAPELLNAFETKFPGVQVQEAYGLTEHSCITLTHSSQGQTPAKRNSVGFILPNIELKFIDPDSGRSLPSNTPGELCVRSQCVMQGYYKNEEETGHTIDKEGWLHTGDVGYIDEDGSVFVVDRIKELIKYKGFQVAPAELEAVLLAHPSVEDAAVIPLPDEDAGEIPAACVVLSQRGKDTTEEDIMEFVGSNVATYKRVRQVHFMEMIPKSASGKIMRRLLKDKILMKKKKITNLLL
>gene:Fes_sc0010201.1.g000004.aua.1
MAADLTNHHNQTQKTPNPNKNYPPWYSPQTGVYNSKFSPIKLPTDPNLDVVSFIFSQKHFGKSALVDSSSGSFISYNELFPLVNSLAFGLYELGVSKGDVVLILLPNSIFYPVILLGVLYLGAIVAPLNPLSSFSEVKKQTLDSHAKWAFTTNSLLEKIKELDVRAIEVPHDVGSISEITKSSIFHTLISSDLKNSSSFRDGIVISQDDTAAIMCSSGTTGASKCVVISHRNLISMVELFVRFEASQYHDEISWCNVYLAVVPMYHIYGLALYAMGLISLGTCIVVMKKFDIDDMVKAIDKYGVTHFPVVPPLLRALTLKAKSLNDGNCALRSLRQVSCGAAATSPLLIDDFVRTFPHVDFIQVPLTFDHLHLNKLSFHFSVVKLNSCCHGYGMTESTAVGARGFNTATVRNYTSAGLLAPNTQAKVVDCITGSCVPPGKAGELWLRGPGTMQGYLNNKEATSTAIEEDGWLHTGDLVYIDHDGYLYILDRLKDMIKYKGFQIAPADLEAILMTHPEILDASVIGVADERVGEVPVAYVVRKPDSKLSSNEVMKYVEMQVAPYKKVRKVVFVHSIPKSPAGKVLRRHLRTMLPSNI
>gene:Fes_sc0029600.1.g000002.aua.1
MPCDLCKYDRAGADGEELLVDSVAVDTGHTIDKEGWIHTGDVVYIDEDGSAFVVNRIKEIINCKGFIILLAHPSVEDAAVILLLDEDAGAIPAACVGLSQRGKATTETANSG
>gene:Fes_sc0060999.1.g000001.aua.1
MPKFDIKAMCELVQKYKVTIAPFVPPIVLAITKSPDVESYDLSSIRLIMSGAAPVGKDLEDAFRAKLPNAVLGQGYGMTEAGPVLAMCLAFAKEPMEVKSGACGTVVRNAELKIVDPETGASLPRNEPGEICIRGSQIMKGYLNDPEATKNTIDEEGWLHTGDIGLVDDNDEIFIVDRLKELIKYKGFQVAPAELEGLLINHPNISDAAVVGMKDEAAGEVPVAFIVKSNGTLITEDDIKKYISDQ
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University