Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Eutrema salsugineum
Species name
Saltwater cress (Eutrema salsugineum) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Eutrema_salsugineum.HIDH.fa
Download
>Thhalv10013981m.v1.0
MAAISFSLNHQSSDNRRGGSHHHHRHGPVVEEIEGLIRVFNDGCVERPPIVPTVSPTVHPSAKVTAFDIKLCNDTWTRVYIPDVAASSPSFTLPLLVYFHGGGFCVGSASWSCYHDFLTSLAVKARCVVVSVDYRLAPEHRLPAAYDDGVSVVSWVLKQHHVSNGGYSSWVSKCNLSNVFLAGDSAGANIAYQVAVRITASGKSVNNLNLKGVILIHPFFGGESRTSSEKKQQQHSKSSALTLSASDTYWRLALPRGASRDHPWCNPLVSSSVGFLREARLPATMVFMAEFDILKDRNLEMCRVMRSLGKRVEGIVHGGVGHAFHILDNSLVSRDRIHDMMCRLRNFIHP
>Thhalv10004622m.v1.0
MDSEIVFDNSPGYRVYKNGRIERLIGETIVPPSLNPQNGVVSKDTLYSPGNNLSVRIYLPEKTSETGEKLPVLVYFHGGGFIIESAFSPTYHNFLTSAVAAADCLAISVDYRRAPEFPIPIPYEDSWNSLKWVFSHIDGSGPENWINKHADFGKVLLAGDSAGGNIAHHLAIRARKEKLESLISGIILIHPYFWGKTPIDEMETRDETKRKRIERSWGIASPNSENGADDPLINVVGSESSDLSGLGCGRVLVIVAGDDAFVRQGLVYAAKVEKSGWEGEVEVMEIKEEGHVHHLKNPFTDNARLVVEKLAEFVNK
>Thhalv10012081m.v1.0
LAPEHPLPTAYEDSWNALQAIQAGNEPWINDYVDFHRFFLVGDSAGANISHHLAFRTKQSDHMTLKIKGIGMIHPYFWGTKPIGSEVTDEARKQMVDGWWRFVCPSEKGSDDPWINPFADGSPDLEGLGCERVMVTVAEKDILRERGKMYYERLVKSEWRGEAEIMETKGKDHVFHIFEPDCDEAMDMLRRLALRDLYITSSVLSYDDSNYSL
>Thhalv10011983m.v1.0
MDSTTKQVSLELFPWLIVHSDGRLERLAGTEVCPPGLDPETGVVSKDIIIDHKTGLSARIYRPDLIQPGQKLPLVLYFHGGAFLIASASFPSYHTSVNKLVDQANIIAVSVNYR
>Thhalv10011580m.v1.0
MLRIFTCSSALRSPSPFFRFLRQFPRSYSSPTSVTISGRNLRRKPTQTTLRLICSHSSSDLVSEHPPFVKIYKDGRIERLSGTETVPASLNPQNGVVSKDVVYSPELNLSVRLFLPQKATELAAGDKIPLLIYIHGGAWIIGSPFSPTYHNFLTEVVKSANCLAVSIQYRRAPEDPIPAAYEDSWSAIQWVFSHSHGSGPVDWINEVADFDRVFLAGDSAGANMSHHMAIRAGKEKLNPRIKGTAIVHPAFWGKDPVDEHDVQDREARRRIAEVWEKLASPNSVDGVDDPLFNVIGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAAKLMKSGWKGDVEVMEEEDEDHCFHLLNPDSENAPKFMKKFVEFIAS
>Thhalv10012216m.v1.0
MNSDLTTDHLPFIRIHENGSVERLSGNDIVPASLNPQNNLPLLIYFHGGAYIVESPFSPVYHNYLTEVVKTSNCLAASVQYRRAPENPIPAAYDDSWSAIQWIFSHSNGSGEEDWINEFADFDRVFVAGDSAGANISHHMAIRAGKEKIKPRIKGVVMKDVQDEGIRRGIKEIWEKIVSPNSVDGVDDPWLNVVGSGSDISGLGCERVLVAVAGKDVFGRQGLAYAAKLEKSGWEGDLEVVEEEGEGHCFHLRNLNCENALKLMKTFREFIIYR
>Thhalv10011663m.v1.0
MESEIASEHLPFIRIYKDGRVERLSGTEIIPPSLDAATNDVVSKDVVYSPEHNLSVRIFLPHKSTAGENKKKLPLLIYIHGGAWIIESPFSPIYHNFLTEIVKSGNFLAVSVQYRRAPENPIPAAYDDSWSAVKWVFSHSDGSGPEDWVNEFADFGKVFIAGDSAGGNMSHHMAIRAGKEKLEPRIKGIAIVHPAFWGRDPVDEKDVQDREMRNGIAEVWEKIASPNSVDGTDDPLFNVVGSGSDFSELACEKVLVAVAGKDVFVRQGLGYAAKLEKSGWVGDVEVVVEEDEGHVFHLQNPNSKNAEKFLKKLVGFIIG
>Thhalv10019529m.v1.0
MGATTLTHETTINPNNTNIDHGPVVDELDGLIRVYTDGHVERPQFEPCVGPSLPLELGVACSDVHIDKLTNVWARLYVPMLTKTSVSKLPLLVYFHGGGFCIGSASWSCYHQFLARLSASSRCLVMSVNYRLAPENPLPAAYEDGVNAVLWLNKTRNDNLWSKLCDFGKIFLAGDSAGGNIANHVAARLAASDDLIKPLKIEGTILIQPFFGGEARTESERRVENNMKSSVLTLEGSDAWWRLALPRGANREHPYCKPVKTMIKMVRTLVCVAEMDVLMDREMEMCDGNEEVIKRVVYKGVGHAFQILGKSQLAHTMTLQMLCHIDAFIHHYHPFN
>Thhalv10028289m.v1.0
MSINPVDEHDLQDREARRRIAVAGKDVFVRQGLGYAVKLMKSGWKGDVEVMEEEDEDHCFHFLNSDSENAPKF
>Thhalv10010541m.v1.0
MDSEIAVDVSPVFKIYKSGRIERLMGETTVPPSSDPENGVVSKDVVYSPDDNLSVRIYLPEKAAAESGEKLPLLVYFHGGGFVIETAFSPTYHTFLTAATSASDCVAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGSGSEDWLNKHADFGKVFLAGDSAGANIAHHMATRAAKEKLCSDLDGGDSGISGIILVHPYFWSRTPIDDKETRDATMRSKIEAFWMMASPNNKDGADDPWINVVKSESVDLSGLGCGKVLVMVAEKDALVRQGLGYAAKLEKSGWKGRVELVESEGEDHVFHLMKPDCDKALEAMQRFSGFIKGDDK
MAAISFSLNHQSSDNRRGGSHHHHRHGPVVEEIEGLIRVFNDGCVERPPIVPTVSPTVHPSAKVTAFDIKLCNDTWTRVYIPDVAASSPSFTLPLLVYFHGGGFCVGSASWSCYHDFLTSLAVKARCVVVSVDYRLAPEHRLPAAYDDGVSVVSWVLKQHHVSNGGYSSWVSKCNLSNVFLAGDSAGANIAYQVAVRITASGKSVNNLNLKGVILIHPFFGGESRTSSEKKQQQHSKSSALTLSASDTYWRLALPRGASRDHPWCNPLVSSSVGFLREARLPATMVFMAEFDILKDRNLEMCRVMRSLGKRVEGIVHGGVGHAFHILDNSLVSRDRIHDMMCRLRNFIHP
>Thhalv10004622m.v1.0
MDSEIVFDNSPGYRVYKNGRIERLIGETIVPPSLNPQNGVVSKDTLYSPGNNLSVRIYLPEKTSETGEKLPVLVYFHGGGFIIESAFSPTYHNFLTSAVAAADCLAISVDYRRAPEFPIPIPYEDSWNSLKWVFSHIDGSGPENWINKHADFGKVLLAGDSAGGNIAHHLAIRARKEKLESLISGIILIHPYFWGKTPIDEMETRDETKRKRIERSWGIASPNSENGADDPLINVVGSESSDLSGLGCGRVLVIVAGDDAFVRQGLVYAAKVEKSGWEGEVEVMEIKEEGHVHHLKNPFTDNARLVVEKLAEFVNK
>Thhalv10012081m.v1.0
LAPEHPLPTAYEDSWNALQAIQAGNEPWINDYVDFHRFFLVGDSAGANISHHLAFRTKQSDHMTLKIKGIGMIHPYFWGTKPIGSEVTDEARKQMVDGWWRFVCPSEKGSDDPWINPFADGSPDLEGLGCERVMVTVAEKDILRERGKMYYERLVKSEWRGEAEIMETKGKDHVFHIFEPDCDEAMDMLRRLALRDLYITSSVLSYDDSNYSL
>Thhalv10011983m.v1.0
MDSTTKQVSLELFPWLIVHSDGRLERLAGTEVCPPGLDPETGVVSKDIIIDHKTGLSARIYRPDLIQPGQKLPLVLYFHGGAFLIASASFPSYHTSVNKLVDQANIIAVSVNYR
>Thhalv10011580m.v1.0
MLRIFTCSSALRSPSPFFRFLRQFPRSYSSPTSVTISGRNLRRKPTQTTLRLICSHSSSDLVSEHPPFVKIYKDGRIERLSGTETVPASLNPQNGVVSKDVVYSPELNLSVRLFLPQKATELAAGDKIPLLIYIHGGAWIIGSPFSPTYHNFLTEVVKSANCLAVSIQYRRAPEDPIPAAYEDSWSAIQWVFSHSHGSGPVDWINEVADFDRVFLAGDSAGANMSHHMAIRAGKEKLNPRIKGTAIVHPAFWGKDPVDEHDVQDREARRRIAEVWEKLASPNSVDGVDDPLFNVIGSGSDFSEMGCEKVLVAVAGKDVFVRQGLGYAAKLMKSGWKGDVEVMEEEDEDHCFHLLNPDSENAPKFMKKFVEFIAS
>Thhalv10012216m.v1.0
MNSDLTTDHLPFIRIHENGSVERLSGNDIVPASLNPQNNLPLLIYFHGGAYIVESPFSPVYHNYLTEVVKTSNCLAASVQYRRAPENPIPAAYDDSWSAIQWIFSHSNGSGEEDWINEFADFDRVFVAGDSAGANISHHMAIRAGKEKIKPRIKGVVMKDVQDEGIRRGIKEIWEKIVSPNSVDGVDDPWLNVVGSGSDISGLGCERVLVAVAGKDVFGRQGLAYAAKLEKSGWEGDLEVVEEEGEGHCFHLRNLNCENALKLMKTFREFIIYR
>Thhalv10011663m.v1.0
MESEIASEHLPFIRIYKDGRVERLSGTEIIPPSLDAATNDVVSKDVVYSPEHNLSVRIFLPHKSTAGENKKKLPLLIYIHGGAWIIESPFSPIYHNFLTEIVKSGNFLAVSVQYRRAPENPIPAAYDDSWSAVKWVFSHSDGSGPEDWVNEFADFGKVFIAGDSAGGNMSHHMAIRAGKEKLEPRIKGIAIVHPAFWGRDPVDEKDVQDREMRNGIAEVWEKIASPNSVDGTDDPLFNVVGSGSDFSELACEKVLVAVAGKDVFVRQGLGYAAKLEKSGWVGDVEVVVEEDEGHVFHLQNPNSKNAEKFLKKLVGFIIG
>Thhalv10019529m.v1.0
MGATTLTHETTINPNNTNIDHGPVVDELDGLIRVYTDGHVERPQFEPCVGPSLPLELGVACSDVHIDKLTNVWARLYVPMLTKTSVSKLPLLVYFHGGGFCIGSASWSCYHQFLARLSASSRCLVMSVNYRLAPENPLPAAYEDGVNAVLWLNKTRNDNLWSKLCDFGKIFLAGDSAGGNIANHVAARLAASDDLIKPLKIEGTILIQPFFGGEARTESERRVENNMKSSVLTLEGSDAWWRLALPRGANREHPYCKPVKTMIKMVRTLVCVAEMDVLMDREMEMCDGNEEVIKRVVYKGVGHAFQILGKSQLAHTMTLQMLCHIDAFIHHYHPFN
>Thhalv10028289m.v1.0
MSINPVDEHDLQDREARRRIAVAGKDVFVRQGLGYAVKLMKSGWKGDVEVMEEEDEDHCFHFLNSDSENAPKF
>Thhalv10010541m.v1.0
MDSEIAVDVSPVFKIYKSGRIERLMGETTVPPSSDPENGVVSKDVVYSPDDNLSVRIYLPEKAAAESGEKLPLLVYFHGGGFVIETAFSPTYHTFLTAATSASDCVAVSVDYRRAPEHPIPISYDDSWTALKWVFSHIAGSGSEDWLNKHADFGKVFLAGDSAGANIAHHMATRAAKEKLCSDLDGGDSGISGIILVHPYFWSRTPIDDKETRDATMRSKIEAFWMMASPNNKDGADDPWINVVKSESVDLSGLGCGKVLVMVAEKDALVRQGLGYAAKLEKSGWKGRVELVESEGEDHVFHLMKPDCDKALEAMQRFSGFIKGDDK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University