Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Euphorbia lathyris
Species name
Euphorbia lathyris is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Euphorbia_lathyris.OMT.fa
Download
>Casp15573.t1
MNQEEAQAEVEKWKYIFGFANMAAVKCAIELKIAEAIENHKTPIPLSTLSSTLNCNPSFLYRIMRFLIHQNIFKQTTLGYEHTPLSLKLLGPGENTFKAFVLLESSPVMIAPWHYLSSRVLVNGTPPFKAAHGGDDLWKYTEGNPGHSKMFDEAMASNARVTVRSVIEKCGEVFDGVGSLVDVGGGNVAKEFHGVSHVGGDMFQSVPNADAASLLWVLHDWNDEECIEILKKCKEVVPKGKGKVIIIEAVVSEEKTDDELEMARLLLDMVMMAHTNTGKERTAKEWEFVIEKAGFSSHSITSIGAVQSIIQCFA
>Casp17371.t1
MKEEEKEEEAQAEVEKWKYIFGFTNMAVVKCAIELGISDAIQNHKSPIPLSDLSSILNCNPSYLHRIMRFLVHQKIFREKPSINGSTGYEQTPLSRKLLGPGENSLKPLFLLESSPVMLAPWHFLSSRVLLNGTGAFEGAHGDDVWKYAEENPGLTTMINEAMASNARLAVRSVIEKCPEIFDGVKSLVDVGGGNEFEGVTNVGGDMFQNVPNADAASLMWVLHDWNDEECIEILKKCKEAIPKENGKVIIIEAVVGEDKIDDKLEIARLLLDMTIMAHTKTGKERTSKEWGFVIQKAGFSSHSISHISSIQSIIQCFP
>Casp17372.t1
MKEEEKEEEAQAEVEKWKYIFGFTNMAVVKCAIELGIADAIENHKSPIPLSDLSSTLNCNPSYLHRIMRFLVHQKIFREKPSINGSTGYEQTPLSRMLLGPGENTLKPLFLLESSPVMLAPWHFLRSRVLLNGTGAFEGAHGDDLWKYWEENPGHSQLFNEAMASNARFAVKSVIQKCPEVFDGVRSLVDVGGGNGTFVSLLVKEFPWINGINFDLPHVVSVNPEFEGVTHVGGDMFQNVPNADAASVMWVLHDWNDEECIAILKKCKEAVPKEKGKVIIIEAIVGENKTDDELEIARLLLDMVIMAHTKTGKERTSKEWEFVIHQAGFSSHSITHISALQSIIQCFP
>Casp17373.t1
MKEEDKEEEAQAEVEKWKYIFGFTNMAVVKCAIELGIADAIENHKSPIPLSDLSSTLNCNPSYLHRIMRFLVHQKIFREKPSINGSTGYEQTPLSRTLLGPGENTLKPMFLLESSPVMLAPWHFLRSRVLLSGSASFKGAHGDDLWKYGEENPDHSQLFNEAMASNARFTVRSLIGKCPEVFDGVKSLVDVGGGNGTSLSLLVEAFPWIDGINFDLPHVVSVAPEFDGVIHVGGDMFQSIPNADAASLMWVLHDWNDEDCIKILKKCKEAIPKENGKVIIIDAVISEEKKDDEMEIARLLMDMVMMAHTNTGKERTSKEWEFVIKKAGFSSHSITFIAALHSVIQCFP
>Casp21121.t1
MTLSELQAALPSKPQHLHRLMRILVDSGFFSLSKTGENRYILTPESLLLLKDHPLSARPYILAVLDPILTEPWQFLSAWFRDEGADSTTAFSMANGNKTMWEMAGSEERFNRVFNGAMESDSWLIGEVLIGKCREVFDGVVDVVDVGGGTGTLGKIVVGAFPRLNCTVLDLPHVVAGLEDSENLRFLAGDMFEFIPPADVIMFKVCVFF
>Casp21124.t1
MVTENQKGDYEATETQLFFDMLMMVVVAGKERDENEWAKLFSDTGFSHYKIIPFLGLRSIIEVYP
>Casp21126.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHSHPKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWNFGSTWFLNDDLTPFDTAHGMSLWDYAGGYPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTAAKAIAKAFPQMECIVLDLPHVVDGIHDTPNLKFVAGNMFHAVPPADAIMLKWILHDWSDQECSKILEQCKKAIKERKGGKVIVIDMVRDNKKGDNEAIETQLFYDMLMMVLVTGKERNEKEWAKLFFDAGFSGYKIIPIMGLRSIIEVYP
>Casp21128.t1
MNNSKNNNSELLKAQAHIWNHIFNFINSMSLKCAVELGIPDIINSHGKPITISELSSALSIHRTKSHCLPRLMRLLIHSGFFALSKTKEQQEEGYVLTNSSQLLLKDNPFSIIPYLQAMLDPVFTKPWNFTSSWFQNDVPSPFEAVHGKALWDYAGCDPKINDLFNNCMDSETRLITSVLINQGKEVFDGLNSVVDVGGGIGTVAKAIAEAFPHIECTVLDLPHVVAGHRDTDNLKYVAGDMFEAVPPADAILIKSTLHDWSDEDCLKILQQCKSAIEERKGGKVIIIDMVIENQKEDNVATETQLFFDMLMMVLVTGKERNEKEWAKLFSAAGFSGYKIVPILGLRSIIEVYP
>Casp21129.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHPKPITISELNAALSIHPSKAHCLPRLMRVLIHSGIFALAKINTKKDEQGEEEEEGYVLTNSSQLLLKDNPFSILPYLLAMLDPICIKPWDFSSTWFLNEDPSPFQTAHGMGFWDYAGRDSKLNNLFNEGMAGDSRLVTSILIDQGKEVFHGLNSIVDVGGGTGTVAKAIAQAFPHIQCTVLDLPQVVDGLHNTPNLKFVAGNMFDSVPPADAILLKWILHDWSVEECLKILDQCKKAIKERGGGKVIIIDMVKENQKEDNVTTETQLFFDMLMMVLVTGKERNEKEWSKLFFAAGFSSYKIIPVMGLRSIIEVYP
>Casp21130.t1
MKVAGKRESVKEGGRLPPEQNRDSRRLLHISGFMEAVAYFEKAGGEVGEGEKEEKRGSRKEERMGKEGQNLFTLGNGSELLEAQAHLWNQIFNFMNSMCLKCAVELGIPDIINSHGKPITISELNSALSIHPTKAHCLPRLMRVLIHSGIFSLAKINTQIDEQGEEEEGYVLTNSSQLLLKDNPFSIIPYLTLMLDPFFIKPWHSTSNWFLNDDPTPFQTAHGMPTWEYTGRDPKLNNEFNDCMTGETRLLMSVLVEKGKEVFDGLNSIVDVAGGVGTAAKVIAEAFPQIECTVLDLPHVVAGHCDTGNLKFVGGNMFEAVPPADAVMIKIKLNWYGTVEIMSSQ
>Casp21131.t1
MNNSKNNSCELLKAQAHIWNHIFNFMNSMCLKCAVELGIPDIINNHGKPITISELNSALYIHPTKAHCLPRLMRLLIHSGFFALSKLNDDDKEEEKEEEGYVLTNSSQLLLKDHPFSLAPLLLLNLDPILAKPWHFTSSWFLNHDPTTFHTSQGMAFWDYVGHDPKINNLFNKAMANDSGLLTNILVDEGKEVFDGLNSVVDVGGGTGTTSKAIAQAFPHIQCTVLDLPQVVDGLHDTPNLKFVAGNMFEAVPPADAVMLKWILHDWSDQECLKILEQCKEAIKGRKGGKVIIIDMVKEIEKGDNEAIETQLFFDMLMMVFFCGKERHEKEWAKLFSTAGYSGYKIIPILD
>Casp21132.t1
MEMVSVENIDELIKAQTQIWSTSLCFIKSMCLKCAVELGIPDIINSHGQPISLSDLVASLPIQSTKTDHVFRLMRILVHSGFFSVETSAEKNNQEEYRLTPASRLLLESTSLGYGEFVSLVLDPVIMQPFEHMSTWLKSDDLNPFITVNGKTLWEKASHEPRLNNLFNDCMAADSGLVAKMVMIKCKEVFEGIDSLVDVAGGTGNMARAIAENFPDMSCTVLDLAQVVNADLETRNNLDFVIGDMFQAVPPADAILLKWILHDWSDQECVKILKNCKDAIAKRKGKQGKIIIIEVVMRNKTWDDNDWSEAQMLFDMEMMGCMVGKERTEKEWAKLFFDSGFIQYKIHPILGPRALIELFP
>Casp21135.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHDKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWHFGSTWFLNDDLTPFHTAHGMSFWDYAGGDPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTADKHSQSISSY
>Casp21403.t1
MRGQAEIWKFMFGFADSMVLKAAVELAIPDIINSHSHPISLSQIASGIDSSSVDMAYLARIMRYLVHKKIFTSHHPPSSSGEIETLYGLTQTSKWILKNSDLTLNPMVIMQNHPSLITPWHYLSQSVKEGETPFKKAHGCEVWDFAAKNSEFNTLFNDALGCTAKIVIKAVLGEESLKCFDGVMSLVDVGGGTGEHLVEILKVKPEIKGVNFDLIHVVSTAPEFEGIVHVGGDMFDVIPKGDAIFMKWILHDWGDENCVKILRNCRKAIPEKTGKLILVEIVLEEDGDNQFGEMGLVFDLLMFAHTSGGKERTEVEWKKLLEDGGFPRYKIIKIPALPSIIEAYPL
>Casp22399.t1
MEFQANIDELFQAQSHIYKHMYHYMESMSLKCAVHLGIPDIIQKHKNPVTLLDLASQLHIPSSKTNSLERVMRILVHSGFFNTTKLNKNQEEEGYVLTPSSALLLKDSNPTLVQTMLDPALVSPCFSLSEWFRSKELTPFETYHGKSFWEYGNDNPEFMNSLNDMMASDSKFTSLIVKEHKEIFQGFSTLVDVGGGTGTLARTISDSYPHIQCTVLDLPQVVANLPGTKNLKFVAGDMFHSVPCADAVLIKSVLHNWSDAACVKILKRCREAIGSSEEGGKLIIIEMVIRNDKKDENGVAETKFFLDLEMMLLSCGKERNEQEWKKLFMEAGFSHYKITATSGLNSIIEVYP
>Casp22400.t1
MRILVFSGFFSTVKIPNNQEQDQDQDQEQEQEAYVLTTSSKLLVTENPNCLTPFVNSLLKLDFVSPGHMLGDWFVGEEVTVFEKAHGMAFWEYNERNPEFNELFNGAMACDSKMMNLVIRDCKPIFKGVNSMVDVGGGNGSLARIISESFPSMKCTVLELPQVISNLQGTKNLEFLGGDMFQHIPSADCVLLKLIMHGWSDEECVKILKKCKEAIGKGGKVIVIDLVINEKKDTHESTETKLLFDMLMMFVATGKERSVKEWENLFLKAGFSHYKFNPLLGLRSLIEVYP
MNQEEAQAEVEKWKYIFGFANMAAVKCAIELKIAEAIENHKTPIPLSTLSSTLNCNPSFLYRIMRFLIHQNIFKQTTLGYEHTPLSLKLLGPGENTFKAFVLLESSPVMIAPWHYLSSRVLVNGTPPFKAAHGGDDLWKYTEGNPGHSKMFDEAMASNARVTVRSVIEKCGEVFDGVGSLVDVGGGNVAKEFHGVSHVGGDMFQSVPNADAASLLWVLHDWNDEECIEILKKCKEVVPKGKGKVIIIEAVVSEEKTDDELEMARLLLDMVMMAHTNTGKERTAKEWEFVIEKAGFSSHSITSIGAVQSIIQCFA
>Casp17371.t1
MKEEEKEEEAQAEVEKWKYIFGFTNMAVVKCAIELGISDAIQNHKSPIPLSDLSSILNCNPSYLHRIMRFLVHQKIFREKPSINGSTGYEQTPLSRKLLGPGENSLKPLFLLESSPVMLAPWHFLSSRVLLNGTGAFEGAHGDDVWKYAEENPGLTTMINEAMASNARLAVRSVIEKCPEIFDGVKSLVDVGGGNEFEGVTNVGGDMFQNVPNADAASLMWVLHDWNDEECIEILKKCKEAIPKENGKVIIIEAVVGEDKIDDKLEIARLLLDMTIMAHTKTGKERTSKEWGFVIQKAGFSSHSISHISSIQSIIQCFP
>Casp17372.t1
MKEEEKEEEAQAEVEKWKYIFGFTNMAVVKCAIELGIADAIENHKSPIPLSDLSSTLNCNPSYLHRIMRFLVHQKIFREKPSINGSTGYEQTPLSRMLLGPGENTLKPLFLLESSPVMLAPWHFLRSRVLLNGTGAFEGAHGDDLWKYWEENPGHSQLFNEAMASNARFAVKSVIQKCPEVFDGVRSLVDVGGGNGTFVSLLVKEFPWINGINFDLPHVVSVNPEFEGVTHVGGDMFQNVPNADAASVMWVLHDWNDEECIAILKKCKEAVPKEKGKVIIIEAIVGENKTDDELEIARLLLDMVIMAHTKTGKERTSKEWEFVIHQAGFSSHSITHISALQSIIQCFP
>Casp17373.t1
MKEEDKEEEAQAEVEKWKYIFGFTNMAVVKCAIELGIADAIENHKSPIPLSDLSSTLNCNPSYLHRIMRFLVHQKIFREKPSINGSTGYEQTPLSRTLLGPGENTLKPMFLLESSPVMLAPWHFLRSRVLLSGSASFKGAHGDDLWKYGEENPDHSQLFNEAMASNARFTVRSLIGKCPEVFDGVKSLVDVGGGNGTSLSLLVEAFPWIDGINFDLPHVVSVAPEFDGVIHVGGDMFQSIPNADAASLMWVLHDWNDEDCIKILKKCKEAIPKENGKVIIIDAVISEEKKDDEMEIARLLMDMVMMAHTNTGKERTSKEWEFVIKKAGFSSHSITFIAALHSVIQCFP
>Casp21121.t1
MTLSELQAALPSKPQHLHRLMRILVDSGFFSLSKTGENRYILTPESLLLLKDHPLSARPYILAVLDPILTEPWQFLSAWFRDEGADSTTAFSMANGNKTMWEMAGSEERFNRVFNGAMESDSWLIGEVLIGKCREVFDGVVDVVDVGGGTGTLGKIVVGAFPRLNCTVLDLPHVVAGLEDSENLRFLAGDMFEFIPPADVIMFKVCVFF
>Casp21124.t1
MVTENQKGDYEATETQLFFDMLMMVVVAGKERDENEWAKLFSDTGFSHYKIIPFLGLRSIIEVYP
>Casp21126.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHSHPKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWNFGSTWFLNDDLTPFDTAHGMSLWDYAGGYPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTAAKAIAKAFPQMECIVLDLPHVVDGIHDTPNLKFVAGNMFHAVPPADAIMLKWILHDWSDQECSKILEQCKKAIKERKGGKVIVIDMVRDNKKGDNEAIETQLFYDMLMMVLVTGKERNEKEWAKLFFDAGFSGYKIIPIMGLRSIIEVYP
>Casp21128.t1
MNNSKNNNSELLKAQAHIWNHIFNFINSMSLKCAVELGIPDIINSHGKPITISELSSALSIHRTKSHCLPRLMRLLIHSGFFALSKTKEQQEEGYVLTNSSQLLLKDNPFSIIPYLQAMLDPVFTKPWNFTSSWFQNDVPSPFEAVHGKALWDYAGCDPKINDLFNNCMDSETRLITSVLINQGKEVFDGLNSVVDVGGGIGTVAKAIAEAFPHIECTVLDLPHVVAGHRDTDNLKYVAGDMFEAVPPADAILIKSTLHDWSDEDCLKILQQCKSAIEERKGGKVIIIDMVIENQKEDNVATETQLFFDMLMMVLVTGKERNEKEWAKLFSAAGFSGYKIVPILGLRSIIEVYP
>Casp21129.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHPKPITISELNAALSIHPSKAHCLPRLMRVLIHSGIFALAKINTKKDEQGEEEEEGYVLTNSSQLLLKDNPFSILPYLLAMLDPICIKPWDFSSTWFLNEDPSPFQTAHGMGFWDYAGRDSKLNNLFNEGMAGDSRLVTSILIDQGKEVFHGLNSIVDVGGGTGTVAKAIAQAFPHIQCTVLDLPQVVDGLHNTPNLKFVAGNMFDSVPPADAILLKWILHDWSVEECLKILDQCKKAIKERGGGKVIIIDMVKENQKEDNVTTETQLFFDMLMMVLVTGKERNEKEWSKLFFAAGFSSYKIIPVMGLRSIIEVYP
>Casp21130.t1
MKVAGKRESVKEGGRLPPEQNRDSRRLLHISGFMEAVAYFEKAGGEVGEGEKEEKRGSRKEERMGKEGQNLFTLGNGSELLEAQAHLWNQIFNFMNSMCLKCAVELGIPDIINSHGKPITISELNSALSIHPTKAHCLPRLMRVLIHSGIFSLAKINTQIDEQGEEEEGYVLTNSSQLLLKDNPFSIIPYLTLMLDPFFIKPWHSTSNWFLNDDPTPFQTAHGMPTWEYTGRDPKLNNEFNDCMTGETRLLMSVLVEKGKEVFDGLNSIVDVAGGVGTAAKVIAEAFPQIECTVLDLPHVVAGHCDTGNLKFVGGNMFEAVPPADAVMIKIKLNWYGTVEIMSSQ
>Casp21131.t1
MNNSKNNSCELLKAQAHIWNHIFNFMNSMCLKCAVELGIPDIINNHGKPITISELNSALYIHPTKAHCLPRLMRLLIHSGFFALSKLNDDDKEEEKEEEGYVLTNSSQLLLKDHPFSLAPLLLLNLDPILAKPWHFTSSWFLNHDPTTFHTSQGMAFWDYVGHDPKINNLFNKAMANDSGLLTNILVDEGKEVFDGLNSVVDVGGGTGTTSKAIAQAFPHIQCTVLDLPQVVDGLHDTPNLKFVAGNMFEAVPPADAVMLKWILHDWSDQECLKILEQCKEAIKGRKGGKVIIIDMVKEIEKGDNEAIETQLFFDMLMMVFFCGKERHEKEWAKLFSTAGYSGYKIIPILD
>Casp21132.t1
MEMVSVENIDELIKAQTQIWSTSLCFIKSMCLKCAVELGIPDIINSHGQPISLSDLVASLPIQSTKTDHVFRLMRILVHSGFFSVETSAEKNNQEEYRLTPASRLLLESTSLGYGEFVSLVLDPVIMQPFEHMSTWLKSDDLNPFITVNGKTLWEKASHEPRLNNLFNDCMAADSGLVAKMVMIKCKEVFEGIDSLVDVAGGTGNMARAIAENFPDMSCTVLDLAQVVNADLETRNNLDFVIGDMFQAVPPADAILLKWILHDWSDQECVKILKNCKDAIAKRKGKQGKIIIIEVVMRNKTWDDNDWSEAQMLFDMEMMGCMVGKERTEKEWAKLFFDSGFIQYKIHPILGPRALIELFP
>Casp21135.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHDKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWHFGSTWFLNDDLTPFHTAHGMSFWDYAGGDPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTADKHSQSISSY
>Casp21403.t1
MRGQAEIWKFMFGFADSMVLKAAVELAIPDIINSHSHPISLSQIASGIDSSSVDMAYLARIMRYLVHKKIFTSHHPPSSSGEIETLYGLTQTSKWILKNSDLTLNPMVIMQNHPSLITPWHYLSQSVKEGETPFKKAHGCEVWDFAAKNSEFNTLFNDALGCTAKIVIKAVLGEESLKCFDGVMSLVDVGGGTGEHLVEILKVKPEIKGVNFDLIHVVSTAPEFEGIVHVGGDMFDVIPKGDAIFMKWILHDWGDENCVKILRNCRKAIPEKTGKLILVEIVLEEDGDNQFGEMGLVFDLLMFAHTSGGKERTEVEWKKLLEDGGFPRYKIIKIPALPSIIEAYPL
>Casp22399.t1
MEFQANIDELFQAQSHIYKHMYHYMESMSLKCAVHLGIPDIIQKHKNPVTLLDLASQLHIPSSKTNSLERVMRILVHSGFFNTTKLNKNQEEEGYVLTPSSALLLKDSNPTLVQTMLDPALVSPCFSLSEWFRSKELTPFETYHGKSFWEYGNDNPEFMNSLNDMMASDSKFTSLIVKEHKEIFQGFSTLVDVGGGTGTLARTISDSYPHIQCTVLDLPQVVANLPGTKNLKFVAGDMFHSVPCADAVLIKSVLHNWSDAACVKILKRCREAIGSSEEGGKLIIIEMVIRNDKKDENGVAETKFFLDLEMMLLSCGKERNEQEWKKLFMEAGFSHYKITATSGLNSIIEVYP
>Casp22400.t1
MRILVFSGFFSTVKIPNNQEQDQDQDQEQEQEAYVLTTSSKLLVTENPNCLTPFVNSLLKLDFVSPGHMLGDWFVGEEVTVFEKAHGMAFWEYNERNPEFNELFNGAMACDSKMMNLVIRDCKPIFKGVNSMVDVGGGNGSLARIISESFPSMKCTVLELPQVISNLQGTKNLEFLGGDMFQHIPSADCVLLKLIMHGWSDEECVKILKKCKEAIGKGGKVIVIDLVINEKKDTHESTETKLLFDMLMMFVATGKERSVKEWENLFLKAGFSHYKFNPLLGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University