Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Euphorbia lathyris
Species name
Euphorbia lathyris is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Euphorbia_lathyris.ROMT.fa
Download
>Casp21121.t1
MTLSELQAALPSKPQHLHRLMRILVDSGFFSLSKTGENRYILTPESLLLLKDHPLSARPYILAVLDPILTEPWQFLSAWFRDEGADSTTAFSMANGNKTMWEMAGSEERFNRVFNGAMESDSWLIGEVLIGKCREVFDGVVDVVDVGGGTGTLGKIVVGAFPRLNCTVLDLPHVVAGLEDSENLRFLAGDMFEFIPPADVIMFKVCVFF
>Casp21124.t1
MVTENQKGDYEATETQLFFDMLMMVVVAGKERDENEWAKLFSDTGFSHYKIIPFLGLRSIIEVYP
>Casp21126.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHSHPKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWNFGSTWFLNDDLTPFDTAHGMSLWDYAGGYPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTAAKAIAKAFPQMECIVLDLPHVVDGIHDTPNLKFVAGNMFHAVPPADAIMLKWILHDWSDQECSKILEQCKKAIKERKGGKVIVIDMVRDNKKGDNEAIETQLFYDMLMMVLVTGKERNEKEWAKLFFDAGFSGYKIIPIMGLRSIIEVYP
>Casp21128.t1
MNNSKNNNSELLKAQAHIWNHIFNFINSMSLKCAVELGIPDIINSHGKPITISELSSALSIHRTKSHCLPRLMRLLIHSGFFALSKTKEQQEEGYVLTNSSQLLLKDNPFSIIPYLQAMLDPVFTKPWNFTSSWFQNDVPSPFEAVHGKALWDYAGCDPKINDLFNNCMDSETRLITSVLINQGKEVFDGLNSVVDVGGGIGTVAKAIAEAFPHIECTVLDLPHVVAGHRDTDNLKYVAGDMFEAVPPADAILIKSTLHDWSDEDCLKILQQCKSAIEERKGGKVIIIDMVIENQKEDNVATETQLFFDMLMMVLVTGKERNEKEWAKLFSAAGFSGYKIVPILGLRSIIEVYP
>Casp21129.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHPKPITISELNAALSIHPSKAHCLPRLMRVLIHSGIFALAKINTKKDEQGEEEEEGYVLTNSSQLLLKDNPFSILPYLLAMLDPICIKPWDFSSTWFLNEDPSPFQTAHGMGFWDYAGRDSKLNNLFNEGMAGDSRLVTSILIDQGKEVFHGLNSIVDVGGGTGTVAKAIAQAFPHIQCTVLDLPQVVDGLHNTPNLKFVAGNMFDSVPPADAILLKWILHDWSVEECLKILDQCKKAIKERGGGKVIIIDMVKENQKEDNVTTETQLFFDMLMMVLVTGKERNEKEWSKLFFAAGFSSYKIIPVMGLRSIIEVYP
>Casp21130.t1
MKVAGKRESVKEGGRLPPEQNRDSRRLLHISGFMEAVAYFEKAGGEVGEGEKEEKRGSRKEERMGKEGQNLFTLGNGSELLEAQAHLWNQIFNFMNSMCLKCAVELGIPDIINSHGKPITISELNSALSIHPTKAHCLPRLMRVLIHSGIFSLAKINTQIDEQGEEEEGYVLTNSSQLLLKDNPFSIIPYLTLMLDPFFIKPWHSTSNWFLNDDPTPFQTAHGMPTWEYTGRDPKLNNEFNDCMTGETRLLMSVLVEKGKEVFDGLNSIVDVAGGVGTAAKVIAEAFPQIECTVLDLPHVVAGHCDTGNLKFVGGNMFEAVPPADAVMIKIKLNWYGTVEIMSSQ
>Casp21131.t1
MNNSKNNSCELLKAQAHIWNHIFNFMNSMCLKCAVELGIPDIINNHGKPITISELNSALYIHPTKAHCLPRLMRLLIHSGFFALSKLNDDDKEEEKEEEGYVLTNSSQLLLKDHPFSLAPLLLLNLDPILAKPWHFTSSWFLNHDPTTFHTSQGMAFWDYVGHDPKINNLFNKAMANDSGLLTNILVDEGKEVFDGLNSVVDVGGGTGTTSKAIAQAFPHIQCTVLDLPQVVDGLHDTPNLKFVAGNMFEAVPPADAVMLKWILHDWSDQECLKILEQCKEAIKGRKGGKVIIIDMVKEIEKGDNEAIETQLFFDMLMMVFFCGKERHEKEWAKLFSTAGYSGYKIIPILD
>Casp21132.t1
MEMVSVENIDELIKAQTQIWSTSLCFIKSMCLKCAVELGIPDIINSHGQPISLSDLVASLPIQSTKTDHVFRLMRILVHSGFFSVETSAEKNNQEEYRLTPASRLLLESTSLGYGEFVSLVLDPVIMQPFEHMSTWLKSDDLNPFITVNGKTLWEKASHEPRLNNLFNDCMAADSGLVAKMVMIKCKEVFEGIDSLVDVAGGTGNMARAIAENFPDMSCTVLDLAQVVNADLETRNNLDFVIGDMFQAVPPADAILLKWILHDWSDQECVKILKNCKDAIAKRKGKQGKIIIIEVVMRNKTWDDNDWSEAQMLFDMEMMGCMVGKERTEKEWAKLFFDSGFIQYKIHPILGPRALIELFP
>Casp21135.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHDKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWHFGSTWFLNDDLTPFHTAHGMSFWDYAGGDPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTADKHSQSISSY
>Casp22399.t1
MEFQANIDELFQAQSHIYKHMYHYMESMSLKCAVHLGIPDIIQKHKNPVTLLDLASQLHIPSSKTNSLERVMRILVHSGFFNTTKLNKNQEEEGYVLTPSSALLLKDSNPTLVQTMLDPALVSPCFSLSEWFRSKELTPFETYHGKSFWEYGNDNPEFMNSLNDMMASDSKFTSLIVKEHKEIFQGFSTLVDVGGGTGTLARTISDSYPHIQCTVLDLPQVVANLPGTKNLKFVAGDMFHSVPCADAVLIKSVLHNWSDAACVKILKRCREAIGSSEEGGKLIIIEMVIRNDKKDENGVAETKFFLDLEMMLLSCGKERNEQEWKKLFMEAGFSHYKITATSGLNSIIEVYP
MTLSELQAALPSKPQHLHRLMRILVDSGFFSLSKTGENRYILTPESLLLLKDHPLSARPYILAVLDPILTEPWQFLSAWFRDEGADSTTAFSMANGNKTMWEMAGSEERFNRVFNGAMESDSWLIGEVLIGKCREVFDGVVDVVDVGGGTGTLGKIVVGAFPRLNCTVLDLPHVVAGLEDSENLRFLAGDMFEFIPPADVIMFKVCVFF
>Casp21124.t1
MVTENQKGDYEATETQLFFDMLMMVVVAGKERDENEWAKLFSDTGFSHYKIIPFLGLRSIIEVYP
>Casp21126.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHSHPKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWNFGSTWFLNDDLTPFDTAHGMSLWDYAGGYPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTAAKAIAKAFPQMECIVLDLPHVVDGIHDTPNLKFVAGNMFHAVPPADAIMLKWILHDWSDQECSKILEQCKKAIKERKGGKVIVIDMVRDNKKGDNEAIETQLFYDMLMMVLVTGKERNEKEWAKLFFDAGFSGYKIIPIMGLRSIIEVYP
>Casp21128.t1
MNNSKNNNSELLKAQAHIWNHIFNFINSMSLKCAVELGIPDIINSHGKPITISELSSALSIHRTKSHCLPRLMRLLIHSGFFALSKTKEQQEEGYVLTNSSQLLLKDNPFSIIPYLQAMLDPVFTKPWNFTSSWFQNDVPSPFEAVHGKALWDYAGCDPKINDLFNNCMDSETRLITSVLINQGKEVFDGLNSVVDVGGGIGTVAKAIAEAFPHIECTVLDLPHVVAGHRDTDNLKYVAGDMFEAVPPADAILIKSTLHDWSDEDCLKILQQCKSAIEERKGGKVIIIDMVIENQKEDNVATETQLFFDMLMMVLVTGKERNEKEWAKLFSAAGFSGYKIVPILGLRSIIEVYP
>Casp21129.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHPKPITISELNAALSIHPSKAHCLPRLMRVLIHSGIFALAKINTKKDEQGEEEEEGYVLTNSSQLLLKDNPFSILPYLLAMLDPICIKPWDFSSTWFLNEDPSPFQTAHGMGFWDYAGRDSKLNNLFNEGMAGDSRLVTSILIDQGKEVFHGLNSIVDVGGGTGTVAKAIAQAFPHIQCTVLDLPQVVDGLHNTPNLKFVAGNMFDSVPPADAILLKWILHDWSVEECLKILDQCKKAIKERGGGKVIIIDMVKENQKEDNVTTETQLFFDMLMMVLVTGKERNEKEWSKLFFAAGFSSYKIIPVMGLRSIIEVYP
>Casp21130.t1
MKVAGKRESVKEGGRLPPEQNRDSRRLLHISGFMEAVAYFEKAGGEVGEGEKEEKRGSRKEERMGKEGQNLFTLGNGSELLEAQAHLWNQIFNFMNSMCLKCAVELGIPDIINSHGKPITISELNSALSIHPTKAHCLPRLMRVLIHSGIFSLAKINTQIDEQGEEEEGYVLTNSSQLLLKDNPFSIIPYLTLMLDPFFIKPWHSTSNWFLNDDPTPFQTAHGMPTWEYTGRDPKLNNEFNDCMTGETRLLMSVLVEKGKEVFDGLNSIVDVAGGVGTAAKVIAEAFPQIECTVLDLPHVVAGHCDTGNLKFVGGNMFEAVPPADAVMIKIKLNWYGTVEIMSSQ
>Casp21131.t1
MNNSKNNSCELLKAQAHIWNHIFNFMNSMCLKCAVELGIPDIINNHGKPITISELNSALYIHPTKAHCLPRLMRLLIHSGFFALSKLNDDDKEEEKEEEGYVLTNSSQLLLKDHPFSLAPLLLLNLDPILAKPWHFTSSWFLNHDPTTFHTSQGMAFWDYVGHDPKINNLFNKAMANDSGLLTNILVDEGKEVFDGLNSVVDVGGGTGTTSKAIAQAFPHIQCTVLDLPQVVDGLHDTPNLKFVAGNMFEAVPPADAVMLKWILHDWSDQECLKILEQCKEAIKGRKGGKVIIIDMVKEIEKGDNEAIETQLFFDMLMMVFFCGKERHEKEWAKLFSTAGYSGYKIIPILD
>Casp21132.t1
MEMVSVENIDELIKAQTQIWSTSLCFIKSMCLKCAVELGIPDIINSHGQPISLSDLVASLPIQSTKTDHVFRLMRILVHSGFFSVETSAEKNNQEEYRLTPASRLLLESTSLGYGEFVSLVLDPVIMQPFEHMSTWLKSDDLNPFITVNGKTLWEKASHEPRLNNLFNDCMAADSGLVAKMVMIKCKEVFEGIDSLVDVAGGTGNMARAIAENFPDMSCTVLDLAQVVNADLETRNNLDFVIGDMFQAVPPADAILLKWILHDWSDQECVKILKNCKDAIAKRKGKQGKIIIIEVVMRNKTWDDNDWSEAQMLFDMEMMGCMVGKERTEKEWAKLFFDSGFIQYKIHPILGPRALIELFP
>Casp21135.t1
MVNLSDSKNKSCELLEAQAHIWNHIFNFINSMSLKCAVELGIPEIIHTHDKPITISELNAALSIHPTKAHCLPRLMRLLIHSGFFALAKTNNQNDDNEEEEGYVLTNSSKLLLNDNPFSVKPFLLAMLDPVLTKPWHFGSTWFLNDDLTPFHTAHGMSFWDYAGGDPKINNFFNEAMASDSRLLSSILIGEGKEVFDGLNSVVDVGGGTGTADKHSQSISSY
>Casp22399.t1
MEFQANIDELFQAQSHIYKHMYHYMESMSLKCAVHLGIPDIIQKHKNPVTLLDLASQLHIPSSKTNSLERVMRILVHSGFFNTTKLNKNQEEEGYVLTPSSALLLKDSNPTLVQTMLDPALVSPCFSLSEWFRSKELTPFETYHGKSFWEYGNDNPEFMNSLNDMMASDSKFTSLIVKEHKEIFQGFSTLVDVGGGTGTLARTISDSYPHIQCTVLDLPQVVANLPGTKNLKFVAGDMFHSVPCADAVLIKSVLHNWSDAACVKILKRCREAIGSSEEGGKLIIIEMVIRNDKKDENGVAETKFFLDLEMMLLSCGKERNEQEWKKLFMEAGFSHYKITATSGLNSIIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University