Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Euphorbia lathyris
Species name
Euphorbia lathyris is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Euphorbia_lathyris.4CL.fa
Download
>Casp12098.t1
MEKSGYGRDGIYRSLRPTPSLPKDTNLSLVSFLFRNSNSYPHKPALIDADLSLTLSFSQLKSISVKVSHGLHHLGISKNDVVLIFAPNSYQFPICFFAITSIGAIATTVNPLYTITEISKQIKDSQPKLIITVPELWDKVKGFNLPIVFLGTKESLSSKPNSKIKTFHDLVELGGSNSEFPVCNLMQSDIAALLYSSGTTGVSKGVILTHRNFIAASLMVTMDQEIAGELHNVFLCFLPMFHIFGLAIITISQLQRGNAVVSMGKFDFEAVLKTVAKYRVTHMWVVPPVVLALAKQSLVKKYDLSSLKQIGSGAAPLGKELMEDCSRSIPNAVIVQGYGMTETTGIVSVENPSIGARNTGSAGMLAAGVEAQIVSVDTLKPLPPNQSGEIWVRGPNMMRGYFNNPKATKETIDKKGWVHTGDLGYFNDEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNTSLTEEDVKQFIANQVAPFKRLRRVSFINIVPKSAAGKILRREMIEKAKSKM
>Casp12827.t1
METKQEEIIFRSKLPDIYIPNHLPLHSYIFQNIANHSSNTCLINGATGQIYTYAEVELTSRRVASGLHKFGIKQGQVIMLLLHNCPEFVLAFLGASFRGAIATAANPLFTPAEIAKQAIASNTKLIITQAAYAEKVKDLENVKIICIDSAPDGCFHFSELENSDESELPSVEFSPDDVVALPYSSGTTGLPKGVMLTHKGLVSSVGQQVDGENPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAAIMIMPKFDINSLLQLIQKYKVTVLPIVPPVVLNIAKSPEAEKYDLSSIRMLKSGAAPLGKELEDTVRSKFPRAVLGQGYGMTEAGPVLAMCLAFAKEPFEIKAGACGTVVRNAEMKIVDPETGLSLPRNQAGEICIRGDQIMKGYLNDPEATTRTIDKQGWLHTGDIGFIDDDDELFIVDRLKELIKFKGYQVAPAELEAMLLAHPQISDAAVVAMKDESAGEVPVAFVVRSEESSITEDEIKQYISKQVVFYKRIKSVFFTQDNICLHNEADDNIDNFHDNTSLNDDAPEVSIEHNTIDEEEGRSDVDTSDPTSDNSDPLQIMLNSPSFNSSIEIPSVSTSINTETSSPNDQDLQNSTSIAPNPSILPRVSSRTSKKPNWLSDFVTNRAADDQCCCSKKQGVPAFIKSYFSAAKGKQEGENQTATDMDLYAMILANKVSQWSHDIDALSVRWDGKEMYIPVDGEAEWGNERKVQVERTDDRNSITVKVEGLVERDIKVRPIGKWENIVHKYELPENDAFAHLETQFKFNNLSNLVEGILGKTYRRDYVSPAKTGVPMPVMGGEDKYQTPSLFSPRCRACRFQTKPALAAI
>Casp18284.t1
MATSPLISSIHTPQEQEHIFRSRYPPVLVPENVTIPQFVLENAELYANNVAFVDSLTGKSYTYGEFTRETKRFAKALRSIGLRKGHVVVVALPNIAEYAIVALGIMAAGGVFSGTNPAGHVSEIKKQAEAADAKLIVTDDTHYGKVKAIELPVIVLGETCNGNAMNWTELLNAADRSTDNYPSEKIEQTDLCALPFSSGTTGLSKGVKLTHRNLVANLCSTLFSVGPEMIGQVTTLGLIPFFHIYGITGICFATLRNKGKVVVMNRFELRLFMNALITHEINFAPIVPPIILALVKNPIVEEFDLSKLKLRAVMTAAAPLAPDLLTAFEVKFPGVQVQEAYGLTEHSCITLSHGDPSKGHGNSKKNSVGYILPNLEIKFVHPETNKSLPVNTHGELCVRSQCVMQGYYKNEEETARTIDIDGWLHTGDIGYIDDEGDIFIVDRIKELIKFKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAACVVINKKAKLSEEDVMNFVAKNVATYKKIRVVQFVDSIPKSPSGKIMRRLLKDKMIEKMKMKNPNSSSSS
>Casp24046.t1
MASGLHRIGIKQGDVVLLLLPNSIYFPILFLGVLYLGAIVTTMNPLSSVSEIHKQIIDCNPCIVFSVLENANKLQSLGIPVIYVPENSTLIKGKKEFEFYKLLYGDSDLGFKPVIRQEDTAAILYSSGTTGSSKGVVLTHRNFISMVEHFVRFEATQYEYSSSENVYLAVLPMFHVYGLSLFVLGMLSLGSSIVIMRRFDANDMVKVIDKYGITHFPVVPPILQALTKKVKDVGGISLKSLKQVSSGAAPLYAKTIQDFVETFPQVDFIQGYGMTESTAVGTRGFNTENLQKYSSIGLLAPNMEAKIVDWVTGRFLPPGSSGELWIRGPAVMKEYLNNSKATALTIDEDGWLHTGDIVYIDCDGYLYIVDRLKEVIKYKGFQIAPADLEAVLLCHPDIVDAAVTAATDKECGEIPVAFVVKRQGSTVTQEAIMHYVAKQVTPYKKVRKVMFVESIPKSAAGKILRRELRRSIASRL
>Casp27015.t1
MELRNHNQEFIFRSKLPDIDIPNHLPLHSYCFQNISQFKDNPCLINGITGDIYTYADVELTSRKVAAGLHKLGVKQGEVIMLLLQNSPEFVFAFLGASYIGAMCTTANPFYTPAEIKKQAVASKAKVIITQGVYAEKVKEFARENDIEIITTDLEDEFCRHFSELTKGDENEIPSVKISADDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNEKDVILCVLPLFHIYSLNSVLMCGLRVGAAILIMQKYDIVSLMELIQKYKVTIAPFVPPIVLAIAKNPMIDKYDLSSVRMVLSGAAPMGKELEDTVRAKLVNAVLGQGYGMTEAGPVLAMCLAFAKEPYEIKSGACGTVVRNAEMKIVDPETGDSLPRNQPGEICIRGDQIMKGYLNDPESTESAIDKEGWLHTGDVGYIDDDDELFIVDRLKELIKYNGFQVAPAELEAMLITHPNISDAAVVPMKDEAAGEIPVAFVVKSNGSKITEDEIQKYISKQVIYYKRIRKVFFTKSIPKAPSGKILRKDLRARLAAATPN
>Casp29177.t1
MISIAPLEPPKQQVSSPQNHKSSSQTHVFRSKLPDIPISNHLPLHDYCFQYLPNFSDRPCLISGSTGKIYTFSETHLLSRKAASGLSNLGIKKGDVIMILLQNCPEFVYSFMAASMIGAVTTTANPFYTRNEILKQFSSSGAKLIITQSLYVDKLRDVQGLDFTIITIDAPPENCVHFSTLISESEIPNVVNFEEDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGINPNLYLKQEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMHKFEIGTLLELIQRHKVSVAAVVPPLVLALAKNPMVAAYDLSSIRVVLSGAAPLGKDLEDALRNRVPQAIIGQGYGMTEAGPVVSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGTSLSYNQPGEICIRGHQIMKGYLNDQEATANTVDVQGWLHTGDIGYVDDDDEVFIVDRLKEIIKFKGFQVPPAELEALLLHHQSIADAAVVPQKDEAAGEVPVAFVVPSNGFHLTEHAVKEYIANQVVFYKRLHRVYFVHAIPKSPSGKILRKDLKTKLATPSSLSS
>Casp34592.t1
MELRNHNQEFIFRSKLPDIDIPNHLPLHSYCFQNISQFKDNPCLINGATGDIYTYADVELTSRKVAAGLHKLGVKQGAVIMLLLQNSPEFVFAFLGASYIGAMCTTANPFYTLAEIKKTSGSVEGESYNCGWKIQNFRRPEFLEIFRILEISRNSGKFLEFLESKF
>Casp35430.t1
MVRSYNPQTQVYSSPRPTINLPTDPNLSLTSFLFQSTLSFPHSVALIDADSGETFTFHQLRVQVSRLAHALIKLNIAKNDVVLILAPNSIHFPICFLAIVSSGAIASTCNPAYTSAELAKQIKDCNPKLIVTVPELIHKVKQFDLPLILLNSHNSDDSLSNSKTWSYFDLLKLPGEVSDLPRNDVKQNDIAALFYSSGTTGTSKGVILTHRNFIASSLMVTADQDRYKEPKSVFLCFLPMFHIMGFVVTTYSQLRRGNTAVCMEKFELSKMLRSIEKYRVTHVYVVPPVMIALAKQNAVKNFDLSSLQVLGSGAAPLGKDVMEECSKNLPHVNIMQGYGMTETCGIISLENPREGTYLSGSTGVLVPGVESQIVSVNTSKPLPPNQLGEICLRGANMMQGYFNNPQATKLTIDEQGWMHTGDLGYFNDEGQLFVVDRIKELIKCNGFQVAPAELEGLLLSHSEILDAVAIPFPDAKAGEVPIAYVVRSPNSSLTEEDIKKFIEPQVAPYKRLRRVTFINSVPKSAAGKILRRELIEKARSKM
MEKSGYGRDGIYRSLRPTPSLPKDTNLSLVSFLFRNSNSYPHKPALIDADLSLTLSFSQLKSISVKVSHGLHHLGISKNDVVLIFAPNSYQFPICFFAITSIGAIATTVNPLYTITEISKQIKDSQPKLIITVPELWDKVKGFNLPIVFLGTKESLSSKPNSKIKTFHDLVELGGSNSEFPVCNLMQSDIAALLYSSGTTGVSKGVILTHRNFIAASLMVTMDQEIAGELHNVFLCFLPMFHIFGLAIITISQLQRGNAVVSMGKFDFEAVLKTVAKYRVTHMWVVPPVVLALAKQSLVKKYDLSSLKQIGSGAAPLGKELMEDCSRSIPNAVIVQGYGMTETTGIVSVENPSIGARNTGSAGMLAAGVEAQIVSVDTLKPLPPNQSGEIWVRGPNMMRGYFNNPKATKETIDKKGWVHTGDLGYFNDEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNTSLTEEDVKQFIANQVAPFKRLRRVSFINIVPKSAAGKILRREMIEKAKSKM
>Casp12827.t1
METKQEEIIFRSKLPDIYIPNHLPLHSYIFQNIANHSSNTCLINGATGQIYTYAEVELTSRRVASGLHKFGIKQGQVIMLLLHNCPEFVLAFLGASFRGAIATAANPLFTPAEIAKQAIASNTKLIITQAAYAEKVKDLENVKIICIDSAPDGCFHFSELENSDESELPSVEFSPDDVVALPYSSGTTGLPKGVMLTHKGLVSSVGQQVDGENPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAAIMIMPKFDINSLLQLIQKYKVTVLPIVPPVVLNIAKSPEAEKYDLSSIRMLKSGAAPLGKELEDTVRSKFPRAVLGQGYGMTEAGPVLAMCLAFAKEPFEIKAGACGTVVRNAEMKIVDPETGLSLPRNQAGEICIRGDQIMKGYLNDPEATTRTIDKQGWLHTGDIGFIDDDDELFIVDRLKELIKFKGYQVAPAELEAMLLAHPQISDAAVVAMKDESAGEVPVAFVVRSEESSITEDEIKQYISKQVVFYKRIKSVFFTQDNICLHNEADDNIDNFHDNTSLNDDAPEVSIEHNTIDEEEGRSDVDTSDPTSDNSDPLQIMLNSPSFNSSIEIPSVSTSINTETSSPNDQDLQNSTSIAPNPSILPRVSSRTSKKPNWLSDFVTNRAADDQCCCSKKQGVPAFIKSYFSAAKGKQEGENQTATDMDLYAMILANKVSQWSHDIDALSVRWDGKEMYIPVDGEAEWGNERKVQVERTDDRNSITVKVEGLVERDIKVRPIGKWENIVHKYELPENDAFAHLETQFKFNNLSNLVEGILGKTYRRDYVSPAKTGVPMPVMGGEDKYQTPSLFSPRCRACRFQTKPALAAI
>Casp18284.t1
MATSPLISSIHTPQEQEHIFRSRYPPVLVPENVTIPQFVLENAELYANNVAFVDSLTGKSYTYGEFTRETKRFAKALRSIGLRKGHVVVVALPNIAEYAIVALGIMAAGGVFSGTNPAGHVSEIKKQAEAADAKLIVTDDTHYGKVKAIELPVIVLGETCNGNAMNWTELLNAADRSTDNYPSEKIEQTDLCALPFSSGTTGLSKGVKLTHRNLVANLCSTLFSVGPEMIGQVTTLGLIPFFHIYGITGICFATLRNKGKVVVMNRFELRLFMNALITHEINFAPIVPPIILALVKNPIVEEFDLSKLKLRAVMTAAAPLAPDLLTAFEVKFPGVQVQEAYGLTEHSCITLSHGDPSKGHGNSKKNSVGYILPNLEIKFVHPETNKSLPVNTHGELCVRSQCVMQGYYKNEEETARTIDIDGWLHTGDIGYIDDEGDIFIVDRIKELIKFKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPAACVVINKKAKLSEEDVMNFVAKNVATYKKIRVVQFVDSIPKSPSGKIMRRLLKDKMIEKMKMKNPNSSSSS
>Casp24046.t1
MASGLHRIGIKQGDVVLLLLPNSIYFPILFLGVLYLGAIVTTMNPLSSVSEIHKQIIDCNPCIVFSVLENANKLQSLGIPVIYVPENSTLIKGKKEFEFYKLLYGDSDLGFKPVIRQEDTAAILYSSGTTGSSKGVVLTHRNFISMVEHFVRFEATQYEYSSSENVYLAVLPMFHVYGLSLFVLGMLSLGSSIVIMRRFDANDMVKVIDKYGITHFPVVPPILQALTKKVKDVGGISLKSLKQVSSGAAPLYAKTIQDFVETFPQVDFIQGYGMTESTAVGTRGFNTENLQKYSSIGLLAPNMEAKIVDWVTGRFLPPGSSGELWIRGPAVMKEYLNNSKATALTIDEDGWLHTGDIVYIDCDGYLYIVDRLKEVIKYKGFQIAPADLEAVLLCHPDIVDAAVTAATDKECGEIPVAFVVKRQGSTVTQEAIMHYVAKQVTPYKKVRKVMFVESIPKSAAGKILRRELRRSIASRL
>Casp27015.t1
MELRNHNQEFIFRSKLPDIDIPNHLPLHSYCFQNISQFKDNPCLINGITGDIYTYADVELTSRKVAAGLHKLGVKQGEVIMLLLQNSPEFVFAFLGASYIGAMCTTANPFYTPAEIKKQAVASKAKVIITQGVYAEKVKEFARENDIEIITTDLEDEFCRHFSELTKGDENEIPSVKISADDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNEKDVILCVLPLFHIYSLNSVLMCGLRVGAAILIMQKYDIVSLMELIQKYKVTIAPFVPPIVLAIAKNPMIDKYDLSSVRMVLSGAAPMGKELEDTVRAKLVNAVLGQGYGMTEAGPVLAMCLAFAKEPYEIKSGACGTVVRNAEMKIVDPETGDSLPRNQPGEICIRGDQIMKGYLNDPESTESAIDKEGWLHTGDVGYIDDDDELFIVDRLKELIKYNGFQVAPAELEAMLITHPNISDAAVVPMKDEAAGEIPVAFVVKSNGSKITEDEIQKYISKQVIYYKRIRKVFFTKSIPKAPSGKILRKDLRARLAAATPN
>Casp29177.t1
MISIAPLEPPKQQVSSPQNHKSSSQTHVFRSKLPDIPISNHLPLHDYCFQYLPNFSDRPCLISGSTGKIYTFSETHLLSRKAASGLSNLGIKKGDVIMILLQNCPEFVYSFMAASMIGAVTTTANPFYTRNEILKQFSSSGAKLIITQSLYVDKLRDVQGLDFTIITIDAPPENCVHFSTLISESEIPNVVNFEEDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGINPNLYLKQEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMHKFEIGTLLELIQRHKVSVAAVVPPLVLALAKNPMVAAYDLSSIRVVLSGAAPLGKDLEDALRNRVPQAIIGQGYGMTEAGPVVSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGTSLSYNQPGEICIRGHQIMKGYLNDQEATANTVDVQGWLHTGDIGYVDDDDEVFIVDRLKEIIKFKGFQVPPAELEALLLHHQSIADAAVVPQKDEAAGEVPVAFVVPSNGFHLTEHAVKEYIANQVVFYKRLHRVYFVHAIPKSPSGKILRKDLKTKLATPSSLSS
>Casp34592.t1
MELRNHNQEFIFRSKLPDIDIPNHLPLHSYCFQNISQFKDNPCLINGATGDIYTYADVELTSRKVAAGLHKLGVKQGAVIMLLLQNSPEFVFAFLGASYIGAMCTTANPFYTLAEIKKTSGSVEGESYNCGWKIQNFRRPEFLEIFRILEISRNSGKFLEFLESKF
>Casp35430.t1
MVRSYNPQTQVYSSPRPTINLPTDPNLSLTSFLFQSTLSFPHSVALIDADSGETFTFHQLRVQVSRLAHALIKLNIAKNDVVLILAPNSIHFPICFLAIVSSGAIASTCNPAYTSAELAKQIKDCNPKLIVTVPELIHKVKQFDLPLILLNSHNSDDSLSNSKTWSYFDLLKLPGEVSDLPRNDVKQNDIAALFYSSGTTGTSKGVILTHRNFIASSLMVTADQDRYKEPKSVFLCFLPMFHIMGFVVTTYSQLRRGNTAVCMEKFELSKMLRSIEKYRVTHVYVVPPVMIALAKQNAVKNFDLSSLQVLGSGAAPLGKDVMEECSKNLPHVNIMQGYGMTETCGIISLENPREGTYLSGSTGVLVPGVESQIVSVNTSKPLPPNQLGEICLRGANMMQGYFNNPQATKLTIDEQGWMHTGDLGYFNDEGQLFVVDRIKELIKCNGFQVAPAELEGLLLSHSEILDAVAIPFPDAKAGEVPIAYVVRSPNSSLTEEDIKKFIEPQVAPYKRLRRVTFINSVPKSAAGKILRRELIEKARSKM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University