Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Eucommia ulmoides
Species name
Eucommia ulmoides is a species of eudicot in the family Eucommiaceae.
Species info
Gene sequence info
Eucommia_ulmoides.COMT.fa
Download
>EUC20646-RA
MNSFTNHDVPPSFDQEAFIHALQLSNSSIFPMVLNTAVELGLFEIIARAGPGERLSARDIASLLPIRENENAPAMLDHVLHLLACNSLLTCTLRAVEDGEVEGMYGMAPAGNFFVRETDGGSVAPLVVLSNGQNSKETWYGK
>EUC20647-RA
MKWVCHNWNDKQCLTLLQNCQKALPQQGKVLILEFLMPLLPDTSVATKIVSDVDNVMLAVYGAKERTKKEFEALSVASGFSKFELVCNIYSNTWLMELTN
>EUC05189-RA
MGTSGVDKLNRRLISTTDHAQGNRPEVQNHMSHAMELVNSLVLPMVLNTTIQLGVLQMIADAGPGAQLSTSDIASRFPANNPDASSMLDRMLRLLASYSVLTCSVVDGGDGRLHRLYGLAPVAKYFVRNQDGASLGDLMALVQDKVYLDSWYVCST
>EUC05188-RA
METSGVDKLNRRLISTTDNAQGNHPEVQNHMPHAMESVSSLVLPMVLNTTIQLGVLQMIADAGPGAQLSSSDIASRFPANNPDAPSMLDRMLRLLASYYIITCSAFDGGDGRLRRL
>EUC05187-RA
MINHTTIVIKELLESYKGFEHLTRLVDVGGGLGITLGMITSKYPSIKGINFDLPHVIRHASAYPGVEHIGGDMFVSVSSGDAIFMKWILHDWSDDQCLKLLKNCYKSLPEEGKVIVVEVVLPEIPDTGSIFRSTSEIDLMMMTQYTGGKERTKQEFLDLAKLAGFQGIRFECFVCNFWVMEFYK
>EUC16188-RA
MGSAIDQSKATPSMAVDEDEAFLFAMQLASASVLPMVMKSAIELDLLESIAKAGPGALVSPADLAAKLPTQNADAPVMLDRILRLLASYSVLSCSLRELPDGKVERLYGLKPVSKFLIKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFDYHGTDPRFNRVFNQGMSNHSTMTMKKILQTYTGFDGLKSVVDVGGGTGATLNMIVSKHPSIKGINFDLPHVIHDAPSYPGVEHVGGDMFASVPKGDAIFMKWICHDWSDEHCLKFLKNCYTALPDAGKVIVAECILPEVPDTKLSTQNVVHIDVIMLAHNPGGKERTEKEFEALAKGAGFNGFRKMCCAYNTWVMEFLKEEA
>EUC06547-RA
MNSWANEEEDEHRQYAMQLASASVLPMVLRGAIELGVLDIIEKAGPDAHISASQILSQLPLAEDNPNAPLLLDRILCLLSTHSILTCSPHKHTNVHLYGLAPVSKYFIPNQDGVSLAPLFQLIQDKTMVNMWYHMKDSVMEGQLPFNRAYGMSASEYISKDGTHLQGLFKNSMRDYNLMFMTRVLETYKGFEGIRSIVDVGGGDGTILNIIVSKYPTIKEAINFDLPPIIENSPAYSGVEYVAGNMFESIPKGEVIFMKWMLHSWDDENCMKILRNCYEALPEKGKVIVVELVIPEAPETSVSVKSTLQFDLFMMNMNPAGKERMEREFETLGKETGFTRVYVACSAFNFSLVEFYKEN
MNSFTNHDVPPSFDQEAFIHALQLSNSSIFPMVLNTAVELGLFEIIARAGPGERLSARDIASLLPIRENENAPAMLDHVLHLLACNSLLTCTLRAVEDGEVEGMYGMAPAGNFFVRETDGGSVAPLVVLSNGQNSKETWYGK
>EUC20647-RA
MKWVCHNWNDKQCLTLLQNCQKALPQQGKVLILEFLMPLLPDTSVATKIVSDVDNVMLAVYGAKERTKKEFEALSVASGFSKFELVCNIYSNTWLMELTN
>EUC05189-RA
MGTSGVDKLNRRLISTTDHAQGNRPEVQNHMSHAMELVNSLVLPMVLNTTIQLGVLQMIADAGPGAQLSTSDIASRFPANNPDASSMLDRMLRLLASYSVLTCSVVDGGDGRLHRLYGLAPVAKYFVRNQDGASLGDLMALVQDKVYLDSWYVCST
>EUC05188-RA
METSGVDKLNRRLISTTDNAQGNHPEVQNHMPHAMESVSSLVLPMVLNTTIQLGVLQMIADAGPGAQLSSSDIASRFPANNPDAPSMLDRMLRLLASYYIITCSAFDGGDGRLRRL
>EUC05187-RA
MINHTTIVIKELLESYKGFEHLTRLVDVGGGLGITLGMITSKYPSIKGINFDLPHVIRHASAYPGVEHIGGDMFVSVSSGDAIFMKWILHDWSDDQCLKLLKNCYKSLPEEGKVIVVEVVLPEIPDTGSIFRSTSEIDLMMMTQYTGGKERTKQEFLDLAKLAGFQGIRFECFVCNFWVMEFYK
>EUC16188-RA
MGSAIDQSKATPSMAVDEDEAFLFAMQLASASVLPMVMKSAIELDLLESIAKAGPGALVSPADLAAKLPTQNADAPVMLDRILRLLASYSVLSCSLRELPDGKVERLYGLKPVSKFLIKNDDGVSMAPLLLMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFDYHGTDPRFNRVFNQGMSNHSTMTMKKILQTYTGFDGLKSVVDVGGGTGATLNMIVSKHPSIKGINFDLPHVIHDAPSYPGVEHVGGDMFASVPKGDAIFMKWICHDWSDEHCLKFLKNCYTALPDAGKVIVAECILPEVPDTKLSTQNVVHIDVIMLAHNPGGKERTEKEFEALAKGAGFNGFRKMCCAYNTWVMEFLKEEA
>EUC06547-RA
MNSWANEEEDEHRQYAMQLASASVLPMVLRGAIELGVLDIIEKAGPDAHISASQILSQLPLAEDNPNAPLLLDRILCLLSTHSILTCSPHKHTNVHLYGLAPVSKYFIPNQDGVSLAPLFQLIQDKTMVNMWYHMKDSVMEGQLPFNRAYGMSASEYISKDGTHLQGLFKNSMRDYNLMFMTRVLETYKGFEGIRSIVDVGGGDGTILNIIVSKYPTIKEAINFDLPPIIENSPAYSGVEYVAGNMFESIPKGEVIFMKWMLHSWDDENCMKILRNCYEALPEKGKVIVVELVIPEAPETSVSVKSTLQFDLFMMNMNPAGKERMEREFETLGKETGFTRVYVACSAFNFSLVEFYKEN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University