Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Eucommia ulmoides
Species name
Eucommia ulmoides is a species of eudicot in the family Eucommiaceae.
Species info
Gene sequence info
Eucommia_ulmoides.ROMT.fa
Download
>EUC05988-RA
MANTETTTDEELLKTQAHVWNQIFNYINSASLKCAVQLGIPEIIHSHNKPISLSNLIASLHINTSKTPFVYRLMRILVHSKFFIQQNNDQLEPEYSLTLASRLLLKDEPFNARSLLLFQLDPILTKPLDFMSQWFQNDNPTAFDTAYGMSFWDYGTKEPMLGEFFNEAMARDSELVRKVLIGEGRGVFEGLKSVVDVGGGSGLVARAIAGAFPDMKCKVLDLPHVVAGLEGTENLEFIGGNMFKEVPSANAVLLKWILHDWSDEEGVKILKKCKAAIPRDGKVIIIDIVMESQKQDHESVETQLFFDLLMMVMVTGKERNEKEWEKLFLGAGFRSYKIIPMLGLRSIIEVYP
>EUC02688-RA
MHDWSNEKCVKILKKCKEAIPSRQNDGKVIIIDMTVQSNNVKSGADKSFETQLFCDMFTMVLYDGREWSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC02690-RA
MANKNFKEDEELLKAQAHVWNQTFNFINSGSLKCAVELGIPDIIHSYGKPMPLSNLISALAINPSKAGCVRRLMRVLAHSGFFLRQKMSKAKEEDEESYGYSLTPSSRLLLKDEPLSVRPLLLAGLDPVLTKPWHFLSGWLEDTGDDDSAAFDMAHGMGFWEYNEKDPRLGVVFNEAMASDSRLVTKVLVNECRYVFEGLTSLVDVGGGTGSVARAIAGMLPRMKCTVLDLPPVVAGLKGTENLDFVAGDMFVEVPKANAVLLKWILHDWNDEDCVKILKKCKEAIPSKENGGKIIIIDMTMENQKQDDESIEAQLFFDMMMMVLFSSKERNEKEWKKLFVGAGLSSYKITPVLGLRSIIEVYP
>EUC02689-RA
MHEEDDELLHSQAHIWNHIFNFVNSMSLKCAIQLGIPDAVHRHGRPITLPVLIAALPVHPPKARCVHRLMRILTHSGFFIKHTLKNDAVMEEDDDSSAATAYSLAPAARLLLKDEPMSATPFLLAMLDPILINPWHDLGRWFQNDEPTAFETAHGRAIWEFAGTEPRLNHFFNDAMASDSRLVAEVVIRDYPEVFDRVGSLVDVGGGTGTVAKAISDAFPEMDCTVIDLPHVVADLTASKNLKYWIMHDWSDEKCVKILKKCKEASPSRQNGGKVIIIDVVVQNNNVKGGADKSFETQLFCDMVTMVLYDGRERSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC02687-RA
MTVQNNNVKGGGTSIGGPDKSFETQLFFDMLMMVVVTGRERSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC21679-RA
MSVTPFLLAMLDPILINPWHDLGRWFQNDDPTPFDTAHGRTLWDFAGTEPQLNLFFNDAMASDARLVAGVVIRNYPEVFDGVGSLVDVGGGTGTVAKAIADAFPKMDCTVLDLPHVVADLNGSKNLKYWILHDWNDEECVKILKKCKEAIPSRQNGGKVIIIDMTVQNNNVKGGTTSIGGPDESFETQLFFDMLMMVLVTGCERSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC20796-RA
MDNIMTTYTDQEILKTQAHIWNHIFNFINSASLKCAVQLGIPEVIHSHAKPMSLSDLVAALPINPSKGRFVYRLMRILVHSGFFLQQKLDQEPEYSLTLASRLLLKDEPFSARSLLLVELDPILTKPWDFLSEWFQNNDPTAFDTAHGIAFWDYNAKEPRLGDFFNEAMASDSRLVIKVLIEECRGVFEGLKSLVDVGGGTGSVARAIAGTFPDMKCTVLDLPNVVAGLEGTENLEFVGGDMFKAVPSANAVLLKWILHDWSDEECVEILKKCKEAIPSRDKGGKVIIIDMLMENKKQDDESVEAQLFFDMLMMVVLTGKERNEKEWKKLFVGAGFKDYKLIPMLGLRSIIEVYP
>EUC20797-RA
MANNEIPTELMHKAKAHIWNQIFSFINSASLKCAVQLGIPDIIHKNGKPMILSELVSKLQINPSESLSLSRLMLVLVRSGIFFYDQEHGYSLTLASRLLLKDEPHNARSFLLVVLDPILTMPFRFLTEWFGNDDPAAFDTAHGLTFWEYHAKEPRLGDLFNDAMASDSGLIAKVLVGECREVFEGLESIVDVGGGTGTAAMAVAEAFPGLKCTVLDLPHVVANLEGTKNLEFVGGDMFQAIPSANAVLLK
>EUC06137-RA
MNVHHEEDDELLHSQAHIWNQIFNFINSMSLKCAIQLGIPDAVHRHGRPITLPELIAALPVHPPKARCVHRLMRILTHSGFFIKHTLKNDAVTEEDDDSFAATAYSLAPASRLLLKDEPMSVTPFLLAMLDPILINPWHDLGRWFQNDDPTPFDTAHGRXTRWRATRGWWRGWSSETTRRCSMGWGRWWTWAAGLGRWPRRSPTLFQRWTVRCSICRTWWRISMGVRT
>EUC06475-RA
MANTEIAIDQELFKAQAQIWNQMFNFVNSASLKCAVQLGIADIIHSHGKPMSLSDLATALHIKPSKAPFLYRLMRILVHSGFFIQQKTGKDDQEQEYSLTLASRLLLKDQNLSARSLVLLELDPVLTKPWAFLSEWFHNDDETAFDTAHGGNIWDYGAKEQRLGDLFNEAMAGDSQLVTKVLTDECRGVFEGLESLVDIGGGTGTVAGAIAKTFPSTNCKVLDLPHVVAGLEKTDNLEFVGGDMFKAVPSANAVLLKWVLHDWSDEECVEILKKCKEAIPSRDKGGKVIIIDMIVESQKQDHKSVETQLFFDLVMMVAVTGKERTEKEWENIFLRAGFRDYKIISTLGLRSLIEVYP
>EUC06474-RA
MANNEIPTELMHKAKAHIWNQIFSFINSASLKCAVQLGIPDIIHKNGKPMILSELVSKLQINPSESLSLSRLMLVLVRSGIFFYDQEHGYSLTLASRLLLKDEPHNARSFLLVVLDPILTMPFRFLTEWFGNDDPAAFDTAHGLTFWEYHAKEPRLGDLFNDAMASDSGLIAKVLVGECREVFEGLESIVDVGGGTGTAAMAVAEAFPGLKCTVLDLPHVVANLEGTKNLEFVGGDMFQAIPSANAVLLKWILHDWNDEECLKILKKCKEAIPNKEGGGKVIIIDMVLENQKQDDEAVEAQLFYDMMMMVLVTGKERNEKDWEKLFLDAGFRAYKVTPVLGLRSLIEVYP
>EUC06478-RA
MANTDTATDQELLKAQAHVWNQVLNFINSGTLKCAVQLGIPDIIHRHGKPMCLSELAAALPVNPSKAPSLHRLMQALVHSGFFIQQNNEQLEPEYSLTLASRLLLKDGNLPFHLRPFLLIHSDPILRKPWDFLSQWFRNDDPTVFDTAHGMPFWDYCSNKESRFGDLFNETMASDSQLMKKVLIDECRGVFEGLDSLVDVGGGSGTVARAIAETFPGMKCTVLELPHVVAGLEGTENLEFVGGDMFKAVPSANAVFLKWILHNWNDDECMTILKKCREAIPSRDKGGKIIIVDMVIDSQKQDHESVETQFFFDLLMMLVLTGKERNEKEWEKLFVGADFKEYKIIPMLGLRSIIEVYP
>EUC06473-RA
MDNIMTTYTDQEILKTQAHIWNHIFNFINSASLKCAVQLGIPEVIHSHAKPMSLSDLVAALPINPSKGRFVYRLMRILVHSGFFLQQKLDQEPEYSLTLASRLLLKDEPFSARSLLLVELDPILTKPWDFLSEWFQNNDPTAFDTAHGIAFWDYNAKEPRLGDFFNEAMASDSRLVIKVLIEECRGVFEGLKSLVDVGGGTGSVARAIAGTFPDMKCTVLDLPNVVAGLEGTENLEFVGGDMFKAVPSANAVLLKWILHDWSDEECVEILKKCKEAIPSRDKGGKVIIIDMLMENKKQDDESVEAQLFFDMLMMVVLTGKERNEKEWKKLFVGAGFKDYKLIPMLGLRSIIEVYP
>EUC06476-RA
MANTDTATDQELLKAQAHVWNQILNYINSSSLKCAVQLGIPDIIHRHGKPMPLSDLITALPITHSKALFIHRLMRVLVHSGFFLQQNNDQSEPEFSLTLASSLLLKDGRFSTRPLSLVLLDPILTKPWDFLSQWFQNDDPTAFDTAHGMPFWDYCANKEPKFGELFNEAMARDSQLVEKVILGECRGVFEGLKSLVDVGGGTGTMARAIAETIPGMKCSVLDLPHVVAGVEGTENLEFVGGDMFKAVPSANAVFLKWILHDWNDEDCVKILKKCKEAIPYKDKGGKIIIVDIVMESQKQDHKSVETQFFFDLLMMMAVTGKERNENEWENLFLGAGFRDYKIIPVLGLRSIIEVYP
MANTETTTDEELLKTQAHVWNQIFNYINSASLKCAVQLGIPEIIHSHNKPISLSNLIASLHINTSKTPFVYRLMRILVHSKFFIQQNNDQLEPEYSLTLASRLLLKDEPFNARSLLLFQLDPILTKPLDFMSQWFQNDNPTAFDTAYGMSFWDYGTKEPMLGEFFNEAMARDSELVRKVLIGEGRGVFEGLKSVVDVGGGSGLVARAIAGAFPDMKCKVLDLPHVVAGLEGTENLEFIGGNMFKEVPSANAVLLKWILHDWSDEEGVKILKKCKAAIPRDGKVIIIDIVMESQKQDHESVETQLFFDLLMMVMVTGKERNEKEWEKLFLGAGFRSYKIIPMLGLRSIIEVYP
>EUC02688-RA
MHDWSNEKCVKILKKCKEAIPSRQNDGKVIIIDMTVQSNNVKSGADKSFETQLFCDMFTMVLYDGREWSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC02690-RA
MANKNFKEDEELLKAQAHVWNQTFNFINSGSLKCAVELGIPDIIHSYGKPMPLSNLISALAINPSKAGCVRRLMRVLAHSGFFLRQKMSKAKEEDEESYGYSLTPSSRLLLKDEPLSVRPLLLAGLDPVLTKPWHFLSGWLEDTGDDDSAAFDMAHGMGFWEYNEKDPRLGVVFNEAMASDSRLVTKVLVNECRYVFEGLTSLVDVGGGTGSVARAIAGMLPRMKCTVLDLPPVVAGLKGTENLDFVAGDMFVEVPKANAVLLKWILHDWNDEDCVKILKKCKEAIPSKENGGKIIIIDMTMENQKQDDESIEAQLFFDMMMMVLFSSKERNEKEWKKLFVGAGLSSYKITPVLGLRSIIEVYP
>EUC02689-RA
MHEEDDELLHSQAHIWNHIFNFVNSMSLKCAIQLGIPDAVHRHGRPITLPVLIAALPVHPPKARCVHRLMRILTHSGFFIKHTLKNDAVMEEDDDSSAATAYSLAPAARLLLKDEPMSATPFLLAMLDPILINPWHDLGRWFQNDEPTAFETAHGRAIWEFAGTEPRLNHFFNDAMASDSRLVAEVVIRDYPEVFDRVGSLVDVGGGTGTVAKAISDAFPEMDCTVIDLPHVVADLTASKNLKYWIMHDWSDEKCVKILKKCKEASPSRQNGGKVIIIDVVVQNNNVKGGADKSFETQLFCDMVTMVLYDGRERSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC02687-RA
MTVQNNNVKGGGTSIGGPDKSFETQLFFDMLMMVVVTGRERSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC21679-RA
MSVTPFLLAMLDPILINPWHDLGRWFQNDDPTPFDTAHGRTLWDFAGTEPQLNLFFNDAMASDARLVAGVVIRNYPEVFDGVGSLVDVGGGTGTVAKAIADAFPKMDCTVLDLPHVVADLNGSKNLKYWILHDWNDEECVKILKKCKEAIPSRQNGGKVIIIDMTVQNNNVKGGTTSIGGPDESFETQLFFDMLMMVLVTGCERSRKDWAKLFSDAGFSDYKITPILGLRSLIEVYP
>EUC20796-RA
MDNIMTTYTDQEILKTQAHIWNHIFNFINSASLKCAVQLGIPEVIHSHAKPMSLSDLVAALPINPSKGRFVYRLMRILVHSGFFLQQKLDQEPEYSLTLASRLLLKDEPFSARSLLLVELDPILTKPWDFLSEWFQNNDPTAFDTAHGIAFWDYNAKEPRLGDFFNEAMASDSRLVIKVLIEECRGVFEGLKSLVDVGGGTGSVARAIAGTFPDMKCTVLDLPNVVAGLEGTENLEFVGGDMFKAVPSANAVLLKWILHDWSDEECVEILKKCKEAIPSRDKGGKVIIIDMLMENKKQDDESVEAQLFFDMLMMVVLTGKERNEKEWKKLFVGAGFKDYKLIPMLGLRSIIEVYP
>EUC20797-RA
MANNEIPTELMHKAKAHIWNQIFSFINSASLKCAVQLGIPDIIHKNGKPMILSELVSKLQINPSESLSLSRLMLVLVRSGIFFYDQEHGYSLTLASRLLLKDEPHNARSFLLVVLDPILTMPFRFLTEWFGNDDPAAFDTAHGLTFWEYHAKEPRLGDLFNDAMASDSGLIAKVLVGECREVFEGLESIVDVGGGTGTAAMAVAEAFPGLKCTVLDLPHVVANLEGTKNLEFVGGDMFQAIPSANAVLLK
>EUC06137-RA
MNVHHEEDDELLHSQAHIWNQIFNFINSMSLKCAIQLGIPDAVHRHGRPITLPELIAALPVHPPKARCVHRLMRILTHSGFFIKHTLKNDAVTEEDDDSFAATAYSLAPASRLLLKDEPMSVTPFLLAMLDPILINPWHDLGRWFQNDDPTPFDTAHGRXTRWRATRGWWRGWSSETTRRCSMGWGRWWTWAAGLGRWPRRSPTLFQRWTVRCSICRTWWRISMGVRT
>EUC06475-RA
MANTEIAIDQELFKAQAQIWNQMFNFVNSASLKCAVQLGIADIIHSHGKPMSLSDLATALHIKPSKAPFLYRLMRILVHSGFFIQQKTGKDDQEQEYSLTLASRLLLKDQNLSARSLVLLELDPVLTKPWAFLSEWFHNDDETAFDTAHGGNIWDYGAKEQRLGDLFNEAMAGDSQLVTKVLTDECRGVFEGLESLVDIGGGTGTVAGAIAKTFPSTNCKVLDLPHVVAGLEKTDNLEFVGGDMFKAVPSANAVLLKWVLHDWSDEECVEILKKCKEAIPSRDKGGKVIIIDMIVESQKQDHKSVETQLFFDLVMMVAVTGKERTEKEWENIFLRAGFRDYKIISTLGLRSLIEVYP
>EUC06474-RA
MANNEIPTELMHKAKAHIWNQIFSFINSASLKCAVQLGIPDIIHKNGKPMILSELVSKLQINPSESLSLSRLMLVLVRSGIFFYDQEHGYSLTLASRLLLKDEPHNARSFLLVVLDPILTMPFRFLTEWFGNDDPAAFDTAHGLTFWEYHAKEPRLGDLFNDAMASDSGLIAKVLVGECREVFEGLESIVDVGGGTGTAAMAVAEAFPGLKCTVLDLPHVVANLEGTKNLEFVGGDMFQAIPSANAVLLKWILHDWNDEECLKILKKCKEAIPNKEGGGKVIIIDMVLENQKQDDEAVEAQLFYDMMMMVLVTGKERNEKDWEKLFLDAGFRAYKVTPVLGLRSLIEVYP
>EUC06478-RA
MANTDTATDQELLKAQAHVWNQVLNFINSGTLKCAVQLGIPDIIHRHGKPMCLSELAAALPVNPSKAPSLHRLMQALVHSGFFIQQNNEQLEPEYSLTLASRLLLKDGNLPFHLRPFLLIHSDPILRKPWDFLSQWFRNDDPTVFDTAHGMPFWDYCSNKESRFGDLFNETMASDSQLMKKVLIDECRGVFEGLDSLVDVGGGSGTVARAIAETFPGMKCTVLELPHVVAGLEGTENLEFVGGDMFKAVPSANAVFLKWILHNWNDDECMTILKKCREAIPSRDKGGKIIIVDMVIDSQKQDHESVETQFFFDLLMMLVLTGKERNEKEWEKLFVGADFKEYKIIPMLGLRSIIEVYP
>EUC06473-RA
MDNIMTTYTDQEILKTQAHIWNHIFNFINSASLKCAVQLGIPEVIHSHAKPMSLSDLVAALPINPSKGRFVYRLMRILVHSGFFLQQKLDQEPEYSLTLASRLLLKDEPFSARSLLLVELDPILTKPWDFLSEWFQNNDPTAFDTAHGIAFWDYNAKEPRLGDFFNEAMASDSRLVIKVLIEECRGVFEGLKSLVDVGGGTGSVARAIAGTFPDMKCTVLDLPNVVAGLEGTENLEFVGGDMFKAVPSANAVLLKWILHDWSDEECVEILKKCKEAIPSRDKGGKVIIIDMLMENKKQDDESVEAQLFFDMLMMVVLTGKERNEKEWKKLFVGAGFKDYKLIPMLGLRSIIEVYP
>EUC06476-RA
MANTDTATDQELLKAQAHVWNQILNYINSSSLKCAVQLGIPDIIHRHGKPMPLSDLITALPITHSKALFIHRLMRVLVHSGFFLQQNNDQSEPEFSLTLASSLLLKDGRFSTRPLSLVLLDPILTKPWDFLSQWFQNDDPTAFDTAHGMPFWDYCANKEPKFGELFNEAMARDSQLVEKVILGECRGVFEGLKSLVDVGGGTGTMARAIAETIPGMKCSVLDLPHVVAGVEGTENLEFVGGDMFKAVPSANAVFLKWILHDWNDEDCVKILKKCKEAIPYKDKGGKIIIVDIVMESQKQDHKSVETQFFFDLLMMMAVTGKERNENEWENLFLGAGFRDYKIIPVLGLRSIIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University